SE9802333D0 - Novel combination - Google Patents
Novel combinationInfo
- Publication number
- SE9802333D0 SE9802333D0 SE9802333A SE9802333A SE9802333D0 SE 9802333 D0 SE9802333 D0 SE 9802333D0 SE 9802333 A SE9802333 A SE 9802333A SE 9802333 A SE9802333 A SE 9802333A SE 9802333 D0 SE9802333 D0 SE 9802333D0
- Authority
- SE
- Sweden
- Prior art keywords
- novel combination
- inhibitor
- cyclooxygenase
- inflammation
- administration
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 abstract 2
- 102000010907 Cyclooxygenase 2 Human genes 0.000 abstract 1
- 108010037462 Cyclooxygenase 2 Proteins 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 102000008299 Nitric Oxide Synthase Human genes 0.000 abstract 1
- 108010021487 Nitric Oxide Synthase Proteins 0.000 abstract 1
- 238000011260 co-administration Methods 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (22)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9802333A SE9802333D0 (sv) | 1998-06-29 | 1998-06-29 | Novel combination |
| TR2000/03808T TR200003808T2 (tr) | 1998-06-29 | 1999-06-23 | Bir cox-2 inhibitörü içeren farmasötik kombinasyon |
| AU49447/99A AU4944799A (en) | 1998-06-29 | 1999-06-23 | A pharmaceutical combination comprising a cox-2 inhibitor and a inos inhibitor |
| IL14002299A IL140022A0 (en) | 1998-06-29 | 1999-06-23 | A pharmaceutical combination comprising a cox-2 inhibitor and a inos inhibitor |
| EP99933384A EP1100505A1 (en) | 1998-06-29 | 1999-06-23 | A PHARMACEUTICAL COMBINATION COMPRISING A COX-2 INHIBITOR AND A iNOS INHIBITOR |
| EEP200000766A EE200000766A (et) | 1998-06-29 | 1999-06-23 | Ravimkoostis, mis sisaldab COX-2 inhibiitorit ja iNOS inhibiitorit |
| SK1848-2000A SK18482000A3 (sk) | 1998-06-29 | 1999-06-23 | Farmaceutická kombinácia obsahujúca inhibítor cox-2 a inhibítor inos |
| JP2000556785A JP2002519324A (ja) | 1998-06-29 | 1999-06-23 | ＣＯＸ−２阻害剤およびｉＮＯＳ阻害剤を含んでなる薬学的組合わせ |
| CZ20004896A CZ20004896A3 (en) | 1998-06-29 | 1999-06-23 | Pharmaceutical preparation containing inhibitor COX-2 and inhibitor iNOS |
| KR1020007014933A KR20010053252A (ko) | 1998-06-29 | 1999-06-23 | ＣＯＸ-2 억제제 및 ｉＮＯＳ 억제제를 포함하는 제약 제제 |
| MXPA00012162 MXPA00012162A (es) | 1998-06-29 | 1999-06-23 | Combinacion farmaceutica que comprende un inhibidor del cox-2 y un inhibidor del i |
| US09/380,379 US6248745B1 (en) | 1998-06-29 | 1999-06-23 | Pharmaceutical combination comprising a COX-2 inhibitor and a iNOS inhibitor |
| IDW20002691A ID27394A (id) | 1998-06-29 | 1999-06-23 | Kombinasi farmasi yang mengandung inhibitor cox-2 dan inhibitor inos |
| PCT/SE1999/001144 WO2000000200A1 (en) | 1998-06-29 | 1999-06-23 | A PHARMACEUTICAL COMBINATION COMPRISING A COX-2 INHIBITOR AND A iNOS INHIBITOR |
| BR9911666-9A BR9911666A (pt) | 1998-06-29 | 1999-06-23 | Combinação farmacêutica, uso da combinação, processo para tratamento de uma doença inflamatória em uma pessoa sofrendo de ou susceptìvel a tal doença, e, composição farmacêutica |
| PL99345028A PL345028A1 (en) | 1998-06-29 | 1999-06-23 | A pharmaceutical combination comprising a cox-2 inhibitor and a inos inhibitor |
| CN99810007A CN1313769A (zh) | 1998-06-29 | 1999-06-23 | 含有COX－2抑制剂和iNOS抑制剂的药物组合 |
| CA002334515A CA2334515A1 (en) | 1998-06-29 | 1999-06-23 | A pharmaceutical combination comprising a cox-2 inhibitor and a inos inhibitor |
| IN721MU2000 IN2000MU00721A (enExample) | 1998-06-29 | 2000-08-01 | |
| ZA200007076A ZA200007076B (en) | 1998-06-29 | 2000-11-30 | A pharmaceutical combination comprising a COX-2 inhibitor and iNOS inhibitor. |
| NO20006559A NO20006559L (no) | 1998-06-29 | 2000-12-21 | Farmasöytisk kombinasjon omfattende en cox-2-inhibitor og en iNOS-inhibitor |
| IS5794A IS5794A (is) | 1998-06-29 | 2000-12-27 | Lyfjasamsetning sem inniheldur COX-2-hemil og iNOS-hemil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9802333A SE9802333D0 (sv) | 1998-06-29 | 1998-06-29 | Novel combination |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE9802333D0 true SE9802333D0 (sv) | 1998-06-29 |
Family
ID=20411898
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE9802333A SE9802333D0 (sv) | 1998-06-29 | 1998-06-29 | Novel combination |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6248745B1 (enExample) |
| EP (1) | EP1100505A1 (enExample) |
| JP (1) | JP2002519324A (enExample) |
| KR (1) | KR20010053252A (enExample) |
| CN (1) | CN1313769A (enExample) |
| AU (1) | AU4944799A (enExample) |
| BR (1) | BR9911666A (enExample) |
| CA (1) | CA2334515A1 (enExample) |
| CZ (1) | CZ20004896A3 (enExample) |
| EE (1) | EE200000766A (enExample) |
| ID (1) | ID27394A (enExample) |
| IL (1) | IL140022A0 (enExample) |
| IN (1) | IN2000MU00721A (enExample) |
| IS (1) | IS5794A (enExample) |
| MX (1) | MXPA00012162A (enExample) |
| NO (1) | NO20006559L (enExample) |
| PL (1) | PL345028A1 (enExample) |
| SE (1) | SE9802333D0 (enExample) |
| SK (1) | SK18482000A3 (enExample) |
| TR (1) | TR200003808T2 (enExample) |
| WO (1) | WO2000000200A1 (enExample) |
| ZA (1) | ZA200007076B (enExample) |
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| US6706724B2 (en) * | 2000-12-21 | 2004-03-16 | Nitromed, Inc. | Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use |
| US7012098B2 (en) * | 2001-03-23 | 2006-03-14 | Pharmacia Corporation | Inhibitors of inducible nitric oxide synthase for chemoprevention and treatment of cancers |
| AU2003207453A1 (en) * | 2002-01-07 | 2003-07-24 | Pharmacia Corp | Treatment of pain, inflammation, and inflammation-related disorders with a combination of a cyclooxygenase-2 selective inhibitor and aspirin |
| CA2487414A1 (en) | 2002-06-11 | 2003-12-18 | Nitromed, Inc. | Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use |
| US20040077691A1 (en) * | 2002-06-21 | 2004-04-22 | Medinox, Inc. | Hydroxamate derivatives of non-steroidal anti-inflammatory drugs |
| EP1539729A4 (en) | 2002-07-03 | 2008-02-20 | Nitromed Inc | NITROSED NON-TESTED OXIDE COMPOUNDS, COMPOSITIONS, AND APPLICATION METHODS |
| JP2005538110A (ja) * | 2002-07-29 | 2005-12-15 | ニトロメッド インコーポレーティッド | シクロオキシゲナーゼ−２選択的阻害剤、組成物、および使用方法 |
| AU2003260033A1 (en) * | 2002-08-29 | 2004-03-19 | Schering Aktiengesellschaft | Methods of treating acute respiratory distress syndrome |
| ATE342722T1 (de) | 2003-05-07 | 2006-11-15 | Osteologix As | Behandlung von knorpel/knochen-erkrankungen mit wasserlöslichen strontiumsalzen |
| AU2006307314C1 (en) | 2005-10-25 | 2011-08-25 | Shionogi & Co., Ltd. | Aminodihydrothiazine derivative |
| JP2007275193A (ja) * | 2006-04-04 | 2007-10-25 | Fujifilm Corp | 光プローブおよび光断層画像化装置 |
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| US20100111858A1 (en) * | 2007-01-19 | 2010-05-06 | Howard Carol P | Diangostic and Therapeutic Cyclooxygenase-2 Binding Ligands |
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| CA2716628A1 (en) * | 2008-03-24 | 2009-10-01 | Carolus Therapeutics, Inc. | Methods and compositions for treating atherosclerosis and related conditions |
| AU2009258496B8 (en) | 2008-06-13 | 2014-06-26 | Shionogi & Co., Ltd. | Sulfur-containing heterocyclic derivative having beta-secretase-inhibiting activity |
| WO2010047372A1 (ja) | 2008-10-22 | 2010-04-29 | 塩野義製薬株式会社 | Ｂａｃｅ１阻害活性を有する２－アミノピリミジン－４－オンおよび２－アミノピリジン誘導体 |
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| MY145791A (en) * | 2009-05-25 | 2012-04-30 | Liang Woon San | A method for producing a nutraceutical composition and the nutraceutical produced by the method |
| UA110467C2 (uk) | 2009-12-11 | 2016-01-12 | Шионогі Енд Ко., Лтд. | Похідні оксазину |
| WO2011077726A1 (ja) * | 2009-12-24 | 2011-06-30 | 塩野義製薬株式会社 | ４－アミノ－１，３－チアジンまたはオキサジン誘導体 |
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| CN108832306B (zh) * | 2018-06-13 | 2023-11-03 | 中国科学院国家天文台 | 一种fast反射面中心孔柔性封堵结构 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5883102A (en) | 1995-10-17 | 1999-03-16 | Astra Pharmaceuticals Limited | Pharmaceutically active compounds |
-
1998
- 1998-06-29 SE SE9802333A patent/SE9802333D0/xx unknown
-
1999
- 1999-06-23 US US09/380,379 patent/US6248745B1/en not_active Expired - Fee Related
- 1999-06-23 ID IDW20002691A patent/ID27394A/id unknown
- 1999-06-23 PL PL99345028A patent/PL345028A1/xx not_active Application Discontinuation
- 1999-06-23 SK SK1848-2000A patent/SK18482000A3/sk unknown
- 1999-06-23 MX MXPA00012162 patent/MXPA00012162A/es unknown
- 1999-06-23 BR BR9911666-9A patent/BR9911666A/pt not_active Application Discontinuation
- 1999-06-23 IL IL14002299A patent/IL140022A0/xx unknown
- 1999-06-23 EP EP99933384A patent/EP1100505A1/en not_active Withdrawn
- 1999-06-23 WO PCT/SE1999/001144 patent/WO2000000200A1/en not_active Ceased
- 1999-06-23 AU AU49447/99A patent/AU4944799A/en not_active Abandoned
- 1999-06-23 EE EEP200000766A patent/EE200000766A/xx unknown
- 1999-06-23 JP JP2000556785A patent/JP2002519324A/ja active Pending
- 1999-06-23 KR KR1020007014933A patent/KR20010053252A/ko not_active Withdrawn
- 1999-06-23 CZ CZ20004896A patent/CZ20004896A3/cs unknown
- 1999-06-23 CA CA002334515A patent/CA2334515A1/en not_active Abandoned
- 1999-06-23 CN CN99810007A patent/CN1313769A/zh active Pending
- 1999-06-23 TR TR2000/03808T patent/TR200003808T2/xx unknown
-
2000
- 2000-08-01 IN IN721MU2000 patent/IN2000MU00721A/en unknown
- 2000-11-30 ZA ZA200007076A patent/ZA200007076B/en unknown
- 2000-12-21 NO NO20006559A patent/NO20006559L/no not_active Application Discontinuation
- 2000-12-27 IS IS5794A patent/IS5794A/is unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1100505A1 (en) | 2001-05-23 |
| ZA200007076B (en) | 2002-02-28 |
| CA2334515A1 (en) | 2000-01-06 |
| BR9911666A (pt) | 2001-03-20 |
| ID27394A (id) | 2001-04-05 |
| WO2000000200A1 (en) | 2000-01-06 |
| IN2000MU00721A (enExample) | 2005-03-18 |
| NO20006559D0 (no) | 2000-12-21 |
| IS5794A (is) | 2000-12-27 |
| EE200000766A (et) | 2002-06-17 |
| CN1313769A (zh) | 2001-09-19 |
| KR20010053252A (ko) | 2001-06-25 |
| SK18482000A3 (sk) | 2001-07-10 |
| US6248745B1 (en) | 2001-06-19 |
| AU4944799A (en) | 2000-01-17 |
| PL345028A1 (en) | 2001-11-19 |
| JP2002519324A (ja) | 2002-07-02 |
| MXPA00012162A (es) | 2001-05-01 |
| IL140022A0 (en) | 2002-02-10 |
| TR200003808T2 (tr) | 2001-06-21 |
| CZ20004896A3 (en) | 2001-06-13 |
| NO20006559L (no) | 2001-02-28 |
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