KR101979035B1 - 열 보조 탈착 이온화 시스템들을 위한 장치 및 방법 - Google Patents
열 보조 탈착 이온화 시스템들을 위한 장치 및 방법 Download PDFInfo
- Publication number
- KR101979035B1 KR101979035B1 KR1020137008108A KR20137008108A KR101979035B1 KR 101979035 B1 KR101979035 B1 KR 101979035B1 KR 1020137008108 A KR1020137008108 A KR 1020137008108A KR 20137008108 A KR20137008108 A KR 20137008108A KR 101979035 B1 KR101979035 B1 KR 101979035B1
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- mesh
- sample
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- ionization
- atmospheric pressure
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
- H01J49/0468—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample
- H01J49/049—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample with means for applying heat to desorb the sample; Evaporation
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
- G01N27/626—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode using heat to ionise a gas
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
- G01N27/64—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode using wave or particle radiation to ionise a gas, e.g. in an ionisation chamber
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J27/00—Ion beam tubes
- H01J27/02—Ion sources; Ion guns
- H01J27/26—Ion sources; Ion guns using surface ionisation, e.g. field effect ion sources, thermionic ion sources
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
- H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/10—Ion sources; Ion guns
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/10—Ion sources; Ion guns
- H01J49/12—Ion sources; Ion guns using an arc discharge, e.g. of the duoplasmatron type
- H01J49/126—Other arc discharge ion sources using an applied magnetic field
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/10—Ion sources; Ion guns
- H01J49/14—Ion sources; Ion guns using particle bombardment, e.g. ionisation chambers
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/24—Vacuum systems, e.g. maintaining desired pressures
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
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- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Plasma & Fusion (AREA)
- Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Electrochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Combustion & Propulsion (AREA)
- Toxicology (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Electron Tubes For Measurement (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161439866P | 2011-02-05 | 2011-02-05 | |
| US61/439,866 | 2011-02-05 | ||
| US201161582204P | 2011-12-30 | 2011-12-30 | |
| US61/582,204 | 2011-12-30 | ||
| US13/364,322 | 2012-01-02 | ||
| US201261587218P | 2012-01-17 | 2012-01-17 | |
| US61/587,218 | 2012-01-17 | ||
| US13/364,322 US8822949B2 (en) | 2011-02-05 | 2012-02-02 | Apparatus and method for thermal assisted desorption ionization systems |
| PCT/US2012/000061 WO2012106054A2 (en) | 2011-02-05 | 2012-02-06 | Apparatus and method for thermal assisted desorption ionization systems |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20140030093A KR20140030093A (ko) | 2014-03-11 |
| KR101979035B1 true KR101979035B1 (ko) | 2019-05-15 |
Family
ID=46600027
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020137008108A Active KR101979035B1 (ko) | 2011-02-05 | 2012-02-06 | 열 보조 탈착 이온화 시스템들을 위한 장치 및 방법 |
Country Status (6)
| Country | Link |
|---|---|
| US (10) | US8822949B2 (enExample) |
| EP (1) | EP2671244B1 (enExample) |
| JP (1) | JP2014508927A (enExample) |
| KR (1) | KR101979035B1 (enExample) |
| CN (1) | CN103443898A (enExample) |
| WO (1) | WO2012106054A2 (enExample) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US9870907B2 (en) * | 2002-03-11 | 2018-01-16 | Jp Scientific Limited | Probe for extraction of molecules of interest from a sample |
| US20090026122A1 (en) | 2002-03-11 | 2009-01-29 | Janusz | Biocompatible solid-phase microextraction coatings and methods for their preparation |
| US7700913B2 (en) | 2006-03-03 | 2010-04-20 | Ionsense, Inc. | Sampling system for use with surface ionization spectroscopy |
| US8026477B2 (en) | 2006-03-03 | 2011-09-27 | Ionsense, Inc. | Sampling system for use with surface ionization spectroscopy |
| US8704167B2 (en) * | 2009-04-30 | 2014-04-22 | Purdue Research Foundation | Mass spectrometry analysis of microorganisms in samples |
| US9500572B2 (en) | 2009-04-30 | 2016-11-22 | Purdue Research Foundation | Sample dispenser including an internal standard and methods of use thereof |
| US8207497B2 (en) | 2009-05-08 | 2012-06-26 | Ionsense, Inc. | Sampling of confined spaces |
| US8932875B2 (en) * | 2011-01-05 | 2015-01-13 | Purdue Research Foundation | Systems and methods for sample analysis |
| US8822949B2 (en) * | 2011-02-05 | 2014-09-02 | Ionsense Inc. | Apparatus and method for thermal assisted desorption ionization systems |
| US8901488B1 (en) | 2011-04-18 | 2014-12-02 | Ionsense, Inc. | Robust, rapid, secure sample manipulation before during and after ionization for a spectroscopy system |
| CN102931046B (zh) * | 2011-08-09 | 2015-12-16 | 中国科学院大连化学物理研究所 | 一种空间聚焦离子门组件及空间聚焦离子迁移管 |
| US9134208B2 (en) * | 2012-07-31 | 2015-09-15 | Smiths Detection Montreal Inc. | Solid phase micro extraction (SPME) vacuum inlet |
| JP2016511396A (ja) * | 2013-01-31 | 2016-04-14 | スミスズ ディテクション モントリオール インコーポレイティド | 表面イオン化源 |
| WO2014120411A1 (en) | 2013-01-31 | 2014-08-07 | Purdue Research Foundation | Systems and methods for analyzing an extracted sample |
| CA2888351A1 (en) | 2013-01-31 | 2014-08-07 | Purdue Research Foundation | Methods of analyzing crude oil |
| WO2014209474A1 (en) | 2013-06-25 | 2014-12-31 | Purdue Research Foundation | Mass spectrometry analysis of microorganisms in samples |
| US9551079B2 (en) * | 2013-09-13 | 2017-01-24 | Purdue Research Foundation | Systems and methods for producing metal clusters; functionalized surfaces; and droplets including solvated metal ions |
| WO2015102053A1 (ja) * | 2014-01-06 | 2015-07-09 | 株式会社島津製作所 | 質量分析装置 |
| US9539622B2 (en) * | 2014-03-18 | 2017-01-10 | Asml Netherlands B.V. | Apparatus for and method of active cleaning of EUV optic with RF plasma field |
| US9297828B2 (en) | 2014-03-27 | 2016-03-29 | Ut-Battelle, Llc | High heating rate thermal desorption for molecular surface sampling |
| EP3130002A4 (en) * | 2014-04-11 | 2017-11-22 | The University of Hong Kong | Method and system of atmospheric pressure megavolt electrostatic field ionization desorption (apme-fid) |
| CN105021718B (zh) * | 2014-04-28 | 2017-06-30 | 南京工业大学 | 一种液相色谱与敞开式离子化质谱在线联用接口和检测方法 |
| US9681557B2 (en) * | 2014-05-30 | 2017-06-13 | Elwha Llc | Metastable gas heating |
| EP3155636B1 (en) * | 2014-06-13 | 2023-11-22 | JP Scientific Limited | A probe for extraction of molecules of interest from a sample |
| US9337007B2 (en) * | 2014-06-15 | 2016-05-10 | Ionsense, Inc. | Apparatus and method for generating chemical signatures using differential desorption |
| US10090139B2 (en) * | 2014-10-15 | 2018-10-02 | Shimadzu Corporation | Mass analysis device |
| US9786478B2 (en) | 2014-12-05 | 2017-10-10 | Purdue Research Foundation | Zero voltage mass spectrometry probes and systems |
| CN107960130A (zh) | 2015-02-06 | 2018-04-24 | 普度研究基金会 | 探针、系统、盒及其使用方法 |
| US9892898B2 (en) * | 2015-11-03 | 2018-02-13 | Joseph J. Bango | Method of improved paper based mass spectrometry and novel wick support structures |
| US9899196B1 (en) | 2016-01-12 | 2018-02-20 | Jeol Usa, Inc. | Dopant-assisted direct analysis in real time mass spectrometry |
| JP6930978B2 (ja) | 2016-03-02 | 2021-09-01 | ジェイ・ピィ・サイエンティフィック・リミテッドJp Scientific Limited | 固相マイクロ抽出用コーティング |
| CN105758930B (zh) * | 2016-03-31 | 2018-08-21 | 东华理工大学 | 一种气热辅助表面解吸常压化学电离源及质谱分析方法 |
| JP6803400B2 (ja) | 2016-05-10 | 2020-12-23 | ジェイ・ピィ・サイエンティフィック・リミテッドJp Scientific Limited | 固相マイクロ抽出装置上に吸着された分析物を脱着および検出するためのシステムおよび方法 |
| CN106483186A (zh) * | 2016-10-11 | 2017-03-08 | 清华大学 | 一种离子化质谱检测装置及其应用 |
| CN106601586B (zh) * | 2016-12-02 | 2019-06-21 | 上海裕达实业有限公司 | 基于电喷雾电离源去溶剂化的加热电离装置 |
| CN106960777B (zh) | 2016-12-31 | 2019-08-20 | 宁波华仪宁创智能科技有限公司 | 质谱分析系统及其工作方法 |
| JP2019002779A (ja) * | 2017-06-14 | 2019-01-10 | 株式会社日立ハイテクソリューションズ | 分析装置 |
| US10636640B2 (en) | 2017-07-06 | 2020-04-28 | Ionsense, Inc. | Apparatus and method for chemical phase sampling analysis |
| CN108364848A (zh) * | 2017-12-31 | 2018-08-03 | 宁波大学 | 便携式离子源及其工作方法 |
| WO2019155740A1 (ja) * | 2018-02-09 | 2019-08-15 | 浜松ホトニクス株式会社 | 試料支持体、及び試料支持体の製造方法 |
| CN110391129B (zh) * | 2018-04-20 | 2020-10-02 | 岛津分析技术研发(上海)有限公司 | 离子化装置、质谱仪、离子迁移谱仪及离子化方法 |
| US10825673B2 (en) | 2018-06-01 | 2020-11-03 | Ionsense Inc. | Apparatus and method for reducing matrix effects |
| CN109243964B (zh) * | 2018-10-18 | 2021-02-09 | 株式会社岛津制作所 | 介质阻挡放电离子源、分析仪器及电离方法 |
| TWI696832B (zh) * | 2018-10-26 | 2020-06-21 | 國立中山大學 | 檢測生物胺的質譜分析方法 |
| JP7705845B2 (ja) | 2019-10-28 | 2025-07-10 | イオンセンス インコーポレイテッド | 大気リアルタイムイオン化 |
| US11569079B2 (en) | 2020-04-13 | 2023-01-31 | Inficon, Inc. | Gas analyzer and membranes therefor |
| US11913861B2 (en) | 2020-05-26 | 2024-02-27 | Bruker Scientific Llc | Electrostatic loading of powder samples for ionization |
| CN112490108B (zh) * | 2020-11-24 | 2021-07-27 | 中国科学院大连化学物理研究所 | 一种自动富集离子的离子门控制方法 |
| TWI816159B (zh) * | 2021-08-02 | 2023-09-21 | 國立臺灣大學 | 用於檢測生物樣品中之短鏈脂肪酸的方法 |
| CN113783093B (zh) * | 2021-09-09 | 2022-04-12 | 中国人民解放军国防科技大学 | 一种基于介质阻挡放电的泵浦约束型DPRGLs系统 |
| AU2022358410A1 (en) * | 2021-10-01 | 2024-04-11 | Shine Technologies, Llc | Ion production system with fibrous lattice for ion collection |
| DE102022100728B4 (de) | 2022-01-13 | 2023-08-24 | Bruker Optics Gmbh & Co. Kg | Desorber für ein Spektrometer |
| US12230490B2 (en) * | 2022-03-31 | 2025-02-18 | Ecole Polytechnique Federale De Lausanne (Epfl) | Device, system, and method for ion fragmentation by use of an ion mobility device and messenger tagging |
| CN115753963A (zh) * | 2022-11-25 | 2023-03-07 | 云南锡业矿冶检测中心有限公司 | 一种高纯镓中锡含量的分析检测方法 |
| US12385818B2 (en) | 2023-02-14 | 2025-08-12 | Saudi Arabian Oil Company | Modeling gas desorption in a subsurface reservoir |
| CN119170482B (zh) * | 2024-08-20 | 2025-10-10 | 湖南大学 | 一种用于微塑料质谱分析的大气压激光解离-二次电喷雾离子源 |
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| JP2007525677A (ja) * | 2004-02-26 | 2007-09-06 | ブリガム・ヤング・ユニバーシティ | 生物由来物質からのバイオマーカーの触媒的生成 |
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