KR101325827B1 - 로수바스타틴 칼슘염의 제조 방법 - Google Patents

로수바스타틴 칼슘염의 제조 방법 Download PDF

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Publication number
KR101325827B1
KR101325827B1 KR1020057002408A KR20057002408A KR101325827B1 KR 101325827 B1 KR101325827 B1 KR 101325827B1 KR 1020057002408 A KR1020057002408 A KR 1020057002408A KR 20057002408 A KR20057002408 A KR 20057002408A KR 101325827 B1 KR101325827 B1 KR 101325827B1
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South Korea
Prior art keywords
fluorophenyl
isopropyl
methyl
methylsulfonyl
amino
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Expired - Lifetime
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KR1020057002408A
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Korean (ko)
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KR20050036968A (ko
Inventor
죤 호버리
니겔 필립 테일러
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아스트라제네카 유케이 리미티드
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020057002408A 2002-08-13 2003-08-07 로수바스타틴 칼슘염의 제조 방법 Expired - Lifetime KR101325827B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0218781.3 2002-08-13
GBGB0218781.3A GB0218781D0 (en) 2002-08-13 2002-08-13 Chemical process
PCT/GB2003/003463 WO2004014872A1 (en) 2002-08-13 2003-08-07 Process for preparing the calcium salt of rosuvastatin

Publications (2)

Publication Number Publication Date
KR20050036968A KR20050036968A (ko) 2005-04-20
KR101325827B1 true KR101325827B1 (ko) 2013-11-05

Family

ID=9942204

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KR1020057002408A Expired - Lifetime KR101325827B1 (ko) 2002-08-13 2003-08-07 로수바스타틴 칼슘염의 제조 방법

Country Status (29)

Country Link
US (2) US7511140B2 (enExample)
EP (1) EP1539711B1 (enExample)
JP (1) JP4588446B2 (enExample)
KR (1) KR101325827B1 (enExample)
CN (1) CN100361979C (enExample)
AR (1) AR040868A1 (enExample)
AT (1) ATE501125T1 (enExample)
AU (1) AU2003251369B2 (enExample)
BR (1) BR0313394A (enExample)
CA (1) CA2495296C (enExample)
CY (1) CY1112412T1 (enExample)
DE (1) DE60336326D1 (enExample)
DK (1) DK1539711T3 (enExample)
ES (1) ES2361009T3 (enExample)
GB (1) GB0218781D0 (enExample)
IL (1) IL166626A (enExample)
IS (1) IS7728A (enExample)
MX (1) MXPA05001582A (enExample)
MY (1) MY135301A (enExample)
NO (1) NO329439B1 (enExample)
NZ (1) NZ538070A (enExample)
PL (1) PL375296A1 (enExample)
PT (1) PT1539711E (enExample)
RU (1) RU2326871C2 (enExample)
SI (1) SI1539711T1 (enExample)
TW (1) TWI316058B (enExample)
UA (1) UA83805C2 (enExample)
WO (1) WO2004014872A1 (enExample)
ZA (1) ZA200500745B (enExample)

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