PT907639E - Compostos polimorficos - Google Patents
Compostos polimorficosInfo
- Publication number
- PT907639E PT907639E PT97929654T PT97929654T PT907639E PT 907639 E PT907639 E PT 907639E PT 97929654 T PT97929654 T PT 97929654T PT 97929654 T PT97929654 T PT 97929654T PT 907639 E PT907639 E PT 907639E
- Authority
- PT
- Portugal
- Prior art keywords
- pct
- fluvastatin sodium
- fluvastatin
- sodium form
- sec
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9602477A SE9602477D0 (sv) | 1996-06-24 | 1996-06-24 | Polymorphic compounds |
SE9700751A SE9700751D0 (sv) | 1997-03-03 | 1997-03-03 | Polymorphic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
PT907639E true PT907639E (pt) | 2003-06-30 |
Family
ID=26662685
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT97929654T PT907639E (pt) | 1996-06-24 | 1997-06-18 | Compostos polimorficos |
Country Status (11)
Country | Link |
---|---|
US (1) | US6124340A (pt) |
EP (1) | EP0907639B1 (pt) |
JP (2) | JP4282092B2 (pt) |
AT (1) | ATE234282T1 (pt) |
AU (1) | AU3366297A (pt) |
CY (1) | CY2461B1 (pt) |
DE (1) | DE69719755T2 (pt) |
DK (1) | DK0907639T3 (pt) |
ES (1) | ES2194202T3 (pt) |
PT (1) | PT907639E (pt) |
WO (1) | WO1997049681A1 (pt) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9902202D0 (sv) * | 1999-06-10 | 1999-06-10 | Astra Ab | Production of aggregates |
US6242003B1 (en) | 2000-04-13 | 2001-06-05 | Novartis Ag | Organic compounds |
CN1210260C (zh) | 2000-10-31 | 2005-07-13 | 西巴特殊化学品控股有限公司 | 氟伐他汀钠的晶形 |
US20060127474A1 (en) | 2001-04-11 | 2006-06-15 | Oskar Kalb | Pharmaceutical compositions comprising fluvastatin |
JP4681808B2 (ja) * | 2001-08-03 | 2011-05-11 | チバ ホールディング インコーポレーテッド | 結晶形 |
GB0218781D0 (en) * | 2002-08-13 | 2002-09-18 | Astrazeneca Ab | Chemical process |
DE10316087A1 (de) * | 2003-04-08 | 2004-11-11 | Ratiopharm Gmbh | Polymorphstabilisierung von Fluvastatin-Natrium in Pharmazeutischen Formulierungen |
WO2004096765A2 (en) * | 2003-05-01 | 2004-11-11 | Morepen Laboratories Ltd. | A novel crystalline polymorph of fluvastatin sodium and a process for preparing it |
GB0312896D0 (en) | 2003-06-05 | 2003-07-09 | Astrazeneca Ab | Chemical process |
US7368581B2 (en) * | 2003-06-18 | 2008-05-06 | Teva Pharmaceutical Industries Ltd. | Process for the preparation of fluvastatin sodium crystal from XIV |
US7368468B2 (en) * | 2003-06-18 | 2008-05-06 | Teva Pharmaceutical Industries Ltd. | Fluvastatin sodium crystal forms XIV, LXXIII, LXXIX, LXXX and LXXXVII, processes for preparing them, compositions containing them and methods of using them |
JP2007524619A (ja) * | 2003-06-18 | 2007-08-30 | テバ ファーマシューティカル インダストリーズ リミティド | フルバスタチンナトリウム結晶型、その調製方法、これを含有する組成物、およびその使用法 |
UY28501A1 (es) | 2003-09-10 | 2005-04-29 | Astrazeneca Uk Ltd | Compuestos químicos |
WO2005037787A1 (en) * | 2003-10-16 | 2005-04-28 | Ciba Specialty Chemicals Holding Inc. | Crystalline form of fluvastatin sodium |
GB0324791D0 (en) | 2003-10-24 | 2003-11-26 | Astrazeneca Ab | Chemical process |
US7851624B2 (en) * | 2003-12-24 | 2010-12-14 | Teva Pharamaceutical Industries Ltd. | Triol form of rosuvastatin and synthesis of rosuvastatin |
US20070179166A1 (en) * | 2003-12-24 | 2007-08-02 | Valerie Niddam-Hildesheim | Process for preparation of statins with high syn to anti ratio |
US7241800B2 (en) | 2004-03-17 | 2007-07-10 | Mai De Ltd. | Anhydrous amorphous form of fluvastatin sodium |
EP1784504A2 (en) * | 2004-07-21 | 2007-05-16 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Oatp-c gene c463a polymorphism underlies variable response of statin therapy |
US7371906B2 (en) * | 2004-08-24 | 2008-05-13 | Eastman Kodak Company | Process for photo-oxidative stability improvements |
WO2006021967A1 (en) * | 2004-08-26 | 2006-03-02 | Biocon Limited | Process for the preparation of fluvastatin sodium form a. |
WO2006030304A2 (en) * | 2004-09-17 | 2006-03-23 | Ranbaxy Laboratories Limited | Novel forms of fluvastatin sodium, processes for preparation and pharmaceutical compositions thereof |
WO2006038219A1 (en) * | 2004-10-05 | 2006-04-13 | Biocon Limited | Process for the preparation of amorphous fluvastatin sodium |
US7795451B2 (en) * | 2005-02-11 | 2010-09-14 | Jubilant Organosys Limited | Polymorphic forms of fluvastatin sodium and process for preparing the same |
WO2006109147A1 (en) * | 2005-04-12 | 2006-10-19 | Glenmark Pharmaceuticals Limited | Substantially pure amorphous fluvastatin, processes for its preparation and pharmaceutical compositions containing same |
CA2642180A1 (en) * | 2006-02-27 | 2007-09-07 | Teva Pharmaceutical Industries Ltd. | Fluvastatin sodium novel forms and preparation therof |
ES2327668T3 (es) | 2006-04-20 | 2009-11-02 | F.I.S. Fabbrica Italiana Sintetici S.P.A. | Procedimiento para la preparacion de sal sodica de fluvastatina. |
CN101250153B (zh) * | 2008-02-26 | 2013-09-18 | 深圳信立泰药业股份有限公司 | 一种制备氟伐他汀钠晶型的工艺 |
EP2419407B1 (en) * | 2009-04-15 | 2012-11-14 | Pharmathen S.A. | Improved process for the preparation of fluvastatin and salts thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4739073A (en) * | 1983-11-04 | 1988-04-19 | Sandoz Pharmaceuticals Corp. | Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof |
AU570021B2 (en) * | 1982-11-22 | 1988-03-03 | Novartis Ag | Analogs of mevalolactone |
HU9203780D0 (en) * | 1991-12-12 | 1993-03-29 | Sandoz Ag | Stabilized pharmaceutical products of hmg-coa reductase inhibitor and method for producing them |
-
1997
- 1997-06-18 ES ES97929654T patent/ES2194202T3/es not_active Expired - Lifetime
- 1997-06-18 JP JP50282198A patent/JP4282092B2/ja not_active Expired - Lifetime
- 1997-06-18 EP EP97929654A patent/EP0907639B1/en not_active Expired - Lifetime
- 1997-06-18 AU AU33662/97A patent/AU3366297A/en not_active Abandoned
- 1997-06-18 WO PCT/SE1997/001097 patent/WO1997049681A1/en active IP Right Grant
- 1997-06-18 DE DE69719755T patent/DE69719755T2/de not_active Expired - Lifetime
- 1997-06-18 AT AT97929654T patent/ATE234282T1/de active
- 1997-06-18 US US08/875,203 patent/US6124340A/en not_active Expired - Lifetime
- 1997-06-18 PT PT97929654T patent/PT907639E/pt unknown
- 1997-06-18 DK DK97929654T patent/DK0907639T3/da active
-
2004
- 2004-06-17 CY CY0400049A patent/CY2461B1/xx unknown
-
2009
- 2009-01-09 JP JP2009003704A patent/JP2009149654A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
WO1997049681A1 (en) | 1997-12-31 |
AU3366297A (en) | 1998-01-14 |
ATE234282T1 (de) | 2003-03-15 |
CY2461B1 (en) | 2005-06-03 |
JP2000512992A (ja) | 2000-10-03 |
EP0907639B1 (en) | 2003-03-12 |
DE69719755T2 (de) | 2003-11-20 |
ES2194202T3 (es) | 2003-11-16 |
DK0907639T3 (da) | 2003-06-23 |
JP2009149654A (ja) | 2009-07-09 |
DE69719755D1 (de) | 2003-04-17 |
EP0907639A1 (en) | 1999-04-14 |
US6124340A (en) | 2000-09-26 |
JP4282092B2 (ja) | 2009-06-17 |
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