AU2003247327A1 - Process for the preparation of amortphous atorvastatin calcium without interconversion of any crystalline form - Google Patents

Process for the preparation of amortphous atorvastatin calcium without interconversion of any crystalline form

Info

Publication number
AU2003247327A1
AU2003247327A1 AU2003247327A AU2003247327A AU2003247327A1 AU 2003247327 A1 AU2003247327 A1 AU 2003247327A1 AU 2003247327 A AU2003247327 A AU 2003247327A AU 2003247327 A AU2003247327 A AU 2003247327A AU 2003247327 A1 AU2003247327 A1 AU 2003247327A1
Authority
AU
Australia
Prior art keywords
amortphous
interconversion
preparation
crystalline form
atorvastatin calcium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003247327A
Inventor
Kadir Dabak
Hulya Keskin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zentiva Kinyasal Urunleri Sanayi ve Ticaret AS
Original Assignee
EOS Eczacibasi Ozgun Kimyasal Urunler Sanayi ve Ticaret AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EOS Eczacibasi Ozgun Kimyasal Urunler Sanayi ve Ticaret AS filed Critical EOS Eczacibasi Ozgun Kimyasal Urunler Sanayi ve Ticaret AS
Publication of AU2003247327A1 publication Critical patent/AU2003247327A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
AU2003247327A 2003-07-15 2003-07-15 Process for the preparation of amortphous atorvastatin calcium without interconversion of any crystalline form Abandoned AU2003247327A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/TR2003/000062 WO2005005384A1 (en) 2003-07-15 2003-07-15 Process for the preparation of amortphous atorvastatin calcium without interconversion of any crystalline form

Publications (1)

Publication Number Publication Date
AU2003247327A1 true AU2003247327A1 (en) 2005-01-28

Family

ID=34057109

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003247327A Abandoned AU2003247327A1 (en) 2003-07-15 2003-07-15 Process for the preparation of amortphous atorvastatin calcium without interconversion of any crystalline form

Country Status (2)

Country Link
AU (1) AU2003247327A1 (en)
WO (1) WO2005005384A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0218781D0 (en) 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
GB0312896D0 (en) 2003-06-05 2003-07-09 Astrazeneca Ab Chemical process
GB0324791D0 (en) 2003-10-24 2003-11-26 Astrazeneca Ab Chemical process
WO2006011155A1 (en) * 2004-07-26 2006-02-02 Apollo International Limited One pot process for amorphous atorvastain calcium
ES2272206T1 (en) * 2004-10-18 2007-05-01 Teva Pharmaceutical Industries Ltd. PROCEDURE FOR THE PREPARATION OF HEMICALCID ATORVASTATIN AMORPHY BY DISSOLVING SALT IN AN ORGANIC SOLVENT WHICH IS A MIXTURE OF A SPIRIT, AND A KETONE AND / OR AN ESTER AND ELIMINATION OF THE SOLVENT.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6087511A (en) * 1996-07-16 2000-07-11 Warner-Lambert Company Process for the production of amorphous [R-(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl )-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid) calcium salt (2:1)
SI20814A (en) * 2001-01-23 2002-08-31 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Preparation of amorphous atorvastatin
IN190564B (en) * 2001-04-11 2003-08-09 Cadila Heathcare Ltd
CZ296967B6 (en) * 2002-02-01 2006-08-16 Zentiva, A.S. Process for preparing amorphous form of hemicalcium salt of (3R,5R)7-[3-phenyl-phenylcarbamoyl-2-(4-fluorophenyl)-5-isopropylpyrrol-l-yl]-3,5-dihydroxyheptanoic acid (atorvastatin)

Also Published As

Publication number Publication date
WO2005005384A1 (en) 2005-01-20

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase