CY1112412T1 - Διεργασια για την παρασκευη του αλατος ασβεστιου της ροσουβαστατινης - Google Patents

Διεργασια για την παρασκευη του αλατος ασβεστιου της ροσουβαστατινης

Info

Publication number
CY1112412T1
CY1112412T1 CY20111100442T CY111100442T CY1112412T1 CY 1112412 T1 CY1112412 T1 CY 1112412T1 CY 20111100442 T CY20111100442 T CY 20111100442T CY 111100442 T CY111100442 T CY 111100442T CY 1112412 T1 CY1112412 T1 CY 1112412T1
Authority
CY
Cyprus
Prior art keywords
preparation
calcium salt
rosuvastatin calcium
useful
dihydroxyept
Prior art date
Application number
CY20111100442T
Other languages
English (en)
Inventor
John Horbury
Nigel Philip Taylor
Original Assignee
Astrazeneca Uk Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9942204&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1112412(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Uk Limited filed Critical Astrazeneca Uk Limited
Publication of CY1112412T1 publication Critical patent/CY1112412T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Περιγράφεται μία βελτιωμένη διεργασία για την παρασκευή άλατος ασβεστίου (Ε)-7-[4-(4-φθοροφαινυλ)-6-ισοπροπυλ-2-[μεθυλ(μεθυλσουλφονυλ)αμινο]πυριμιδιν-5-υλ](3R,5S)-3,5-διυδροξυεπτ-6-ενοϊκού οξέος, το οποίο είναι χρήσιμο για την παραγωγή ενός φαρμακευτικού προϊόντος χρήσιμου στη θεραπεία, μεταξύ άλλων, της υπερχοληστερολαιμίας, της υπερλιποπρωτεϊναιμίας και της αθηροσκλήρωσης.
CY20111100442T 2002-08-13 2011-05-09 Διεργασια για την παρασκευη του αλατος ασβεστιου της ροσουβαστατινης CY1112412T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0218781.3A GB0218781D0 (en) 2002-08-13 2002-08-13 Chemical process
EP03784274A EP1539711B1 (en) 2002-08-13 2003-08-07 Process for preparing the calcium salt of rosuvastatin

Publications (1)

Publication Number Publication Date
CY1112412T1 true CY1112412T1 (el) 2015-12-09

Family

ID=9942204

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111100442T CY1112412T1 (el) 2002-08-13 2011-05-09 Διεργασια για την παρασκευη του αλατος ασβεστιου της ροσουβαστατινης

Country Status (30)

Country Link
US (2) US7511140B2 (el)
EP (1) EP1539711B1 (el)
JP (1) JP4588446B2 (el)
KR (1) KR101325827B1 (el)
CN (1) CN100361979C (el)
AR (1) AR040868A1 (el)
AT (1) ATE501125T1 (el)
AU (1) AU2003251369B2 (el)
BR (1) BR0313394A (el)
CA (1) CA2495296C (el)
CY (1) CY1112412T1 (el)
DE (1) DE60336326D1 (el)
DK (1) DK1539711T3 (el)
ES (1) ES2361009T3 (el)
GB (1) GB0218781D0 (el)
HK (1) HK1082735A1 (el)
IL (1) IL166626A (el)
IS (1) IS7728A (el)
MX (1) MXPA05001582A (el)
MY (1) MY135301A (el)
NO (1) NO329439B1 (el)
NZ (1) NZ538070A (el)
PL (1) PL375296A1 (el)
PT (1) PT1539711E (el)
RU (1) RU2326871C2 (el)
SI (1) SI1539711T1 (el)
TW (1) TWI316058B (el)
UA (1) UA83805C2 (el)
WO (1) WO2004014872A1 (el)
ZA (1) ZA200500745B (el)

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