MXPA05013128A - Produccion mejorada de sal calcica de rosuvastatina. - Google Patents

Produccion mejorada de sal calcica de rosuvastatina.

Info

Publication number
MXPA05013128A
MXPA05013128A MXPA05013128A MXPA05013128A MXPA05013128A MX PA05013128 A MXPA05013128 A MX PA05013128A MX PA05013128 A MXPA05013128 A MX PA05013128A MX PA05013128 A MXPA05013128 A MX PA05013128A MX PA05013128 A MXPA05013128 A MX PA05013128A
Authority
MX
Mexico
Prior art keywords
calcium salt
improved production
rosuvastatin calcium
useful
production
Prior art date
Application number
MXPA05013128A
Other languages
English (en)
Inventor
Nigel Phillip Taylor
Original Assignee
Astrazeneca Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33512687&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MXPA05013128(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd
Publication of MXPA05013128A publication Critical patent/MXPA05013128A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invencion se refiere a un proceso mejorado para la manufactura de la sal calcica del acido (E)-7-[4- (4-fluorofenil)-6 -isopropil-2 -[metil(metilsulfonil) amino]pirimidin- 5-il](3R, 5S)-3, 5-dihidroxihept -6-enoico, Formula (1), el cual es util para la produccion de una sustancia farmaceutica util en el tratamiento de, inter alia, hipercolesterolemia, hiperlipoproteinemia y aterosclerosis.
MXPA05013128A 2003-06-05 2004-06-03 Produccion mejorada de sal calcica de rosuvastatina. MXPA05013128A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0312896.4A GB0312896D0 (en) 2003-06-05 2003-06-05 Chemical process
GBGB0324793.9A GB0324793D0 (en) 2003-06-05 2003-10-24 Chemical process
PCT/GB2004/002373 WO2004108691A1 (en) 2003-06-05 2004-06-03 Improved production of rosuvastatin calcium salt

Publications (1)

Publication Number Publication Date
MXPA05013128A true MXPA05013128A (es) 2006-03-16

Family

ID=33512687

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05013128A MXPA05013128A (es) 2003-06-05 2004-06-03 Produccion mejorada de sal calcica de rosuvastatina.

Country Status (26)

Country Link
US (1) US8063213B2 (es)
EP (1) EP1633727B1 (es)
JP (1) JP4651615B2 (es)
KR (1) KR101099934B1 (es)
CN (1) CN100422157C (es)
AR (1) AR044773A1 (es)
AT (1) ATE464297T1 (es)
AU (1) AU2004245291B2 (es)
BR (1) BRPI0410922B8 (es)
CA (1) CA2527314C (es)
CO (1) CO5640116A2 (es)
DE (1) DE602004026576D1 (es)
ES (1) ES2341858T3 (es)
GB (2) GB0312896D0 (es)
HK (1) HK1087405A1 (es)
IL (1) IL172075A (es)
IS (1) IS2751B (es)
MX (1) MXPA05013128A (es)
MY (1) MY140820A (es)
NO (1) NO332971B1 (es)
NZ (1) NZ543962A (es)
RU (1) RU2361864C2 (es)
SA (1) SA04250223B1 (es)
TW (1) TWI341310B (es)
UY (1) UY28341A1 (es)
WO (1) WO2004108691A1 (es)

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Also Published As

Publication number Publication date
EP1633727B1 (en) 2010-04-14
TW200510337A (en) 2005-03-16
RU2005138370A (ru) 2006-07-10
KR20060017848A (ko) 2006-02-27
DE602004026576D1 (de) 2010-05-27
US20080221323A1 (en) 2008-09-11
AU2004245291A1 (en) 2004-12-16
AU2004245291B2 (en) 2008-02-14
GB0324793D0 (en) 2003-11-26
US8063213B2 (en) 2011-11-22
IS8217A (is) 2006-01-02
JP4651615B2 (ja) 2011-03-16
CA2527314C (en) 2012-02-21
CN100422157C (zh) 2008-10-01
NO20055730L (no) 2005-12-27
TWI341310B (en) 2011-05-01
JP2006526602A (ja) 2006-11-24
NO20055730D0 (no) 2005-12-05
IS2751B (is) 2011-09-15
WO2004108691A1 (en) 2004-12-16
MY140820A (en) 2010-01-29
CO5640116A2 (es) 2006-05-31
GB0312896D0 (en) 2003-07-09
NZ543962A (en) 2008-09-26
IL172075A (en) 2011-06-30
BRPI0410922B1 (pt) 2016-02-23
RU2361864C2 (ru) 2009-07-20
HK1087405A1 (en) 2006-10-13
KR101099934B1 (ko) 2011-12-28
BRPI0410922B8 (pt) 2021-05-25
ES2341858T3 (es) 2010-06-29
EP1633727A1 (en) 2006-03-15
CA2527314A1 (en) 2004-12-16
CN1798741A (zh) 2006-07-05
NO332971B1 (no) 2013-02-11
BRPI0410922A (pt) 2006-06-27
UY28341A1 (es) 2005-01-31
AR044773A1 (es) 2005-10-05
ATE464297T1 (de) 2010-04-15
SA04250223B1 (ar) 2008-12-23

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