KR101141464B1 - 중성구 엘라스타제 억제제로서의 2-피리돈 유도체 및 그의용도 - Google Patents
중성구 엘라스타제 억제제로서의 2-피리돈 유도체 및 그의용도 Download PDFInfo
- Publication number
- KR101141464B1 KR101141464B1 KR1020067005456A KR20067005456A KR101141464B1 KR 101141464 B1 KR101141464 B1 KR 101141464B1 KR 1020067005456 A KR1020067005456 A KR 1020067005456A KR 20067005456 A KR20067005456 A KR 20067005456A KR 101141464 B1 KR101141464 B1 KR 101141464B1
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- South Korea
- Prior art keywords
- methyl
- phenyl
- oxo
- trifluoromethyl
- mmol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
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- C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
- C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
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- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Ceramic Engineering (AREA)
- Manufacturing & Machinery (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Structural Engineering (AREA)
- Materials Engineering (AREA)
- Inorganic Chemistry (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0302486-6 | 2003-09-18 | ||
| SE0302486A SE0302486D0 (sv) | 2003-09-18 | 2003-09-18 | Novel compounds |
| PCT/SE2004/001335 WO2005026123A1 (en) | 2003-09-18 | 2004-09-15 | 2-pyridone derivatives as neutrophil elastase inhibitors and their use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20060087569A KR20060087569A (ko) | 2006-08-02 |
| KR101141464B1 true KR101141464B1 (ko) | 2012-05-24 |
Family
ID=29212488
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020067005456A Expired - Lifetime KR101141464B1 (ko) | 2003-09-18 | 2004-09-15 | 중성구 엘라스타제 억제제로서의 2-피리돈 유도체 및 그의용도 |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US8063073B2 (enExample) |
| EP (1) | EP1663973B3 (enExample) |
| JP (1) | JP4515455B2 (enExample) |
| KR (1) | KR101141464B1 (enExample) |
| CN (1) | CN1882542B (enExample) |
| AR (1) | AR045761A1 (enExample) |
| AU (1) | AU2004272484C1 (enExample) |
| BR (1) | BRPI0414548B8 (enExample) |
| CA (1) | CA2538405C (enExample) |
| CO (1) | CO5670358A2 (enExample) |
| ES (1) | ES2448465T7 (enExample) |
| IL (1) | IL173990A (enExample) |
| IS (1) | IS8381A (enExample) |
| MX (1) | MXPA06002724A (enExample) |
| MY (1) | MY143400A (enExample) |
| NO (1) | NO20061660L (enExample) |
| NZ (1) | NZ545963A (enExample) |
| RU (1) | RU2353616C2 (enExample) |
| SA (1) | SA04250299B1 (enExample) |
| SE (1) | SE0302486D0 (enExample) |
| TW (1) | TWI354665B (enExample) |
| UY (1) | UY28514A1 (enExample) |
| WO (1) | WO2005026123A1 (enExample) |
| ZA (1) | ZA200602261B (enExample) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200500341A (en) * | 2002-11-12 | 2005-01-01 | Astrazeneca Ab | Novel compounds |
| SE0302487D0 (sv) * | 2003-09-18 | 2003-09-18 | Astrazeneca Ab | Novel compounds |
| SE0302486D0 (sv) * | 2003-09-18 | 2003-09-18 | Astrazeneca Ab | Novel compounds |
| TW200700392A (en) * | 2005-03-16 | 2007-01-01 | Astrazeneca Ab | Novel compounds |
| PT1928454E (pt) | 2005-05-10 | 2014-12-04 | Intermune Inc | Derivativos da piridona para modulação do sistema de proteína quinase ativada pelo stress |
| GB0516313D0 (en) | 2005-08-08 | 2005-09-14 | Argenta Discovery Ltd | Azole derivatives and their uses |
| RU2442771C2 (ru) | 2005-08-08 | 2012-02-20 | Арджента Дискавери Лтд | Производные бицикло[2,2,1]гепт-7-иламина и их применения |
| GB0605469D0 (en) * | 2006-03-17 | 2006-04-26 | Argenta Discovery Ltd | Multimers of heterocyclic compounds and their use |
| TW200808771A (en) * | 2006-05-08 | 2008-02-16 | Astrazeneca Ab | Novel compounds II |
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