KR101098481B1 - 3-치환-2(아릴알킬)-1-아자바이시클로알칸 및 그 사용방법 - Google Patents

3-치환-2(아릴알킬)-1-아자바이시클로알칸 및 그 사용방법 Download PDF

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KR101098481B1
KR101098481B1 KR1020057015424A KR20057015424A KR101098481B1 KR 101098481 B1 KR101098481 B1 KR 101098481B1 KR 1020057015424 A KR1020057015424 A KR 1020057015424A KR 20057015424 A KR20057015424 A KR 20057015424A KR 101098481 B1 KR101098481 B1 KR 101098481B1
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pyridinyl
azabicyclo
methyl
oct
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KR20060002770A (ko
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안나톨리 에이. 마주로프
조제프 크루시크
란 미아오
안젤라 에스. 시먼스
테레사 영피터 필립스
제프리 다니엘 슈미트
크레이그 해리슨 밀러
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타가셉트 인코포레이티드
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    • C07—ORGANIC CHEMISTRY
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
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    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

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KR1020057015424A 2003-02-21 2004-02-20 3-치환-2(아릴알킬)-1-아자바이시클로알칸 및 그 사용방법 Expired - Fee Related KR101098481B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/372,642 US6953855B2 (en) 1998-12-11 2003-02-21 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof
US10/372,642 2003-02-21

Related Child Applications (2)

Application Number Title Priority Date Filing Date
KR1020107026477A Division KR101098480B1 (ko) 2003-02-21 2004-02-20 3­치환­2（아릴알킬）­1­아자바이시클로알칸 및 그 사용방법
KR1020107026476A Division KR101098490B1 (ko) 2003-02-21 2004-02-20 3­치환­2（아릴알킬）­1­아자바이시클로알칸 및 그 사용방법

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KR20060002770A KR20060002770A (ko) 2006-01-09
KR101098481B1 true KR101098481B1 (ko) 2011-12-26

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KR1020057015424A Expired - Fee Related KR101098481B1 (ko) 2003-02-21 2004-02-20 3-치환-2(아릴알킬)-1-아자바이시클로알칸 및 그 사용방법
KR1020107026476A Expired - Fee Related KR101098490B1 (ko) 2003-02-21 2004-02-20 3­치환­2（아릴알킬）­1­아자바이시클로알칸 및 그 사용방법
KR1020107026477A Expired - Fee Related KR101098480B1 (ko) 2003-02-21 2004-02-20 3­치환­2（아릴알킬）­1­아자바이시클로알칸 및 그 사용방법

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KR1020107026476A Expired - Fee Related KR101098490B1 (ko) 2003-02-21 2004-02-20 3­치환­2（아릴알킬）­1­아자바이시클로알칸 및 그 사용방법
KR1020107026477A Expired - Fee Related KR101098480B1 (ko) 2003-02-21 2004-02-20 3­치환­2（아릴알킬）­1­아자바이시클로알칸 및 그 사용방법

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US (11) US6953855B2 (enExample)
EP (1) EP1594869B9 (enExample)
JP (3) JP4828407B2 (enExample)
KR (3) KR101098481B1 (enExample)
CN (2) CN1751041B (enExample)
AT (1) ATE381563T1 (enExample)
AU (1) AU2004215386B2 (enExample)
BR (1) BRPI0407708A (enExample)
CA (1) CA2514135C (enExample)
CY (1) CY1107175T1 (enExample)
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NZ (3) NZ541794A (enExample)
PL (3) PL395717A1 (enExample)
PT (1) PT1594869E (enExample)
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US6953855B2 (en) * 1998-12-11 2005-10-11 Targacept, Inc. 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
GB0220581D0 (en) 2002-09-04 2002-10-09 Novartis Ag Organic Compound
MXPA05003317A (es) * 2002-09-25 2005-07-05 Memory Pharm Corp Indazoles, benzotiazoles y benzoisotiazoles asi como preparacion y usos de los mismos.
US7750022B2 (en) 2003-08-13 2010-07-06 Neurosearch A/S Quinuclidine derivatives and their pharmaceutical use
JP4824578B2 (ja) * 2003-12-22 2011-11-30 メモリー・ファーマシューティカルズ・コーポレイション インドール類、１，２−ベンズイソオキサゾール類、および１，２−ベンゾイソチアゾール類、ならびにそれらの製造と使用
SE0400708D0 (sv) * 2004-03-22 2004-03-22 Aprea Ab New compounds and use thereof
RU2417225C2 (ru) 2004-03-25 2011-04-27 Мемори Фармасьютиклз Корпорейшн Индазолы, бензотиазолы, бензоизотиазолы, бензизоксазолы и их получение и применение
WO2006001894A1 (en) * 2004-04-22 2006-01-05 Memory Pharmaceutical Corporation Indoles, 1h-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof
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AR049401A1 (es) 2004-06-18 2006-07-26 Novartis Ag Aza-biciclononanos
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
CN101124224A (zh) * 2004-12-22 2008-02-13 记忆药物公司 烟碱性α-7受体配体及其制备和用途
EP1910328A1 (en) * 2005-06-29 2008-04-16 AstraZeneca AB Thiophene-2-carboxamide derivatives as alpha 7 nicotinic receptor modulators
US20070082939A1 (en) * 2005-07-26 2007-04-12 Lippa Arnold S Methods and compositions for the treatment of neuropathies and related disorders
JP2009506037A (ja) 2005-08-22 2009-02-12 ターガセプト，インコーポレイテッド ヘテロアリール置換ジアザトリシクロアルカン、その調製方法およびその使用方法
US8106066B2 (en) * 2005-09-23 2012-01-31 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
JP2009510090A (ja) * 2005-09-27 2009-03-12 ミリアド ジェネティックス インコーポレーティッド 治療化合物としてのピロール誘導体
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