KR101063585B1 - 피리딜 비방향족 질소 함유 헤테로환-1-카르복실산에스테르 유도체 - Google Patents

피리딜 비방향족 질소 함유 헤테로환-1-카르복실산에스테르 유도체 Download PDF

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KR101063585B1
KR101063585B1 KR1020097011570A KR20097011570A KR101063585B1 KR 101063585 B1 KR101063585 B1 KR 101063585B1 KR 1020097011570 A KR1020097011570 A KR 1020097011570A KR 20097011570 A KR20097011570 A KR 20097011570A KR 101063585 B1 KR101063585 B1 KR 101063585B1
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leu
gly
ser
ala
val
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KR20090078841A (ko
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다까히로 이시이
다까시 수가네
준 마에다
후미에 나라자끼
아끼오 가께후다
겐따로 사또
다쯔히사 다까하시
다까또시 가나야마
치까시 사이또
조따로 스즈끼
치사또 가나이
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아스텔라스세이야쿠 가부시키가이샤
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • A—HUMAN NECESSITIES
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Neurosurgery (AREA)
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  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
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  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Otolaryngology (AREA)
  • Nutrition Science (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
KR1020097011570A 2005-02-17 2006-02-16 피리딜 비방향족 질소 함유 헤테로환-1-카르복실산에스테르 유도체 Expired - Fee Related KR101063585B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2005040197 2005-02-17
JPJP-P-2005-040197 2005-02-17
JPJP-P-2005-303065 2005-10-18
JP2005303065 2005-10-18
PCT/JP2006/302698 WO2006088075A1 (ja) 2005-02-17 2006-02-16 ピリジル 非芳香族含窒素ヘテロ環－１－カルボン酸エステル誘導体

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KR1020077020924A Division KR101063663B1 (ko) 2005-02-17 2006-02-16 피리딜 비방향족 질소 함유 헤테로환-1-카르복실산에스테르유도체

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KR20090078841A KR20090078841A (ko) 2009-07-20
KR101063585B1 true KR101063585B1 (ko) 2011-09-07

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KR1020097011570A Expired - Fee Related KR101063585B1 (ko) 2005-02-17 2006-02-16 피리딜 비방향족 질소 함유 헤테로환-1-카르복실산에스테르 유도체
KR1020077020924A Active KR101063663B1 (ko) 2005-02-17 2006-02-16 피리딜 비방향족 질소 함유 헤테로환-1-카르복실산에스테르유도체
KR1020097011569A Expired - Fee Related KR101065979B1 (ko) 2005-02-17 2006-02-16 피리딜 비방향족 질소 함유 헤테로환-1-카르복실산에스테르 유도체

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KR1020097011569A Expired - Fee Related KR101065979B1 (ko) 2005-02-17 2006-02-16 피리딜 비방향족 질소 함유 헤테로환-1-카르복실산에스테르 유도체

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US (3) US7919495B2 (enExample)
EP (2) EP1849773B1 (enExample)
JP (1) JP4702361B2 (enExample)
KR (3) KR101063585B1 (enExample)
CN (1) CN101160287B (enExample)
AU (3) AU2006215080B2 (enExample)
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EP2065369A4 (en) 2006-08-23 2011-12-28 Astellas Pharma Inc UREA CONNECTION OR SALT THEREOF
SI2076508T1 (sl) 2006-10-18 2011-04-29 Pfizer Prod Inc Spojine biaril eter sečnine
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CN102056900A (zh) * 2008-04-07 2011-05-11 Irm责任有限公司 作为gpr119活性调节剂的化合物和组合物
WO2009143404A1 (en) * 2008-05-23 2009-11-26 Wyeth Piperazine metabotropic glutamate receptor 5 (mglur5) negative allosteric modulators for anxiety/depression
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BRPI0921692A2 (pt) 2008-11-06 2018-06-26 Astellas Pharma Inc composto carbamato ou o sal do mesmo
CN102256963B (zh) 2008-12-19 2014-06-11 贝林格尔.英格海姆国际有限公司 作为ccr2受体拮抗剂用于治疗炎症、哮喘和copd的环状嘧啶-4-甲酰胺
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PL2513093T3 (pl) 2009-12-17 2015-03-31 Centrexion Therapeutics Corp Nowi antagoniści receptora CCR2 i ich zastosowanie
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