KR100665204B1 - 글리코펩티드 유도체 및 그를 포함하는 약학적 조성물 - Google Patents

글리코펩티드 유도체 및 그를 포함하는 약학적 조성물 Download PDF

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Publication number
KR100665204B1
KR100665204B1 KR1020017003918A KR20017003918A KR100665204B1 KR 100665204 B1 KR100665204 B1 KR 100665204B1 KR 1020017003918 A KR1020017003918 A KR 1020017003918A KR 20017003918 A KR20017003918 A KR 20017003918A KR 100665204 B1 KR100665204 B1 KR 100665204B1
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KR
South Korea
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alkyl
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aryl
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Expired - Lifetime
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KR1020017003918A
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English (en)
Korean (ko)
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KR20010085857A (ko
Inventor
주디스제이.케빈
파더리폴로스
램버니스엠.티.
레드베터마이클
린셀마틴세링햄
무용키
트랩션게리
양구앙
주얀
Original Assignee
세라밴스 인코포레이티드
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Publication of KR20010085857A publication Critical patent/KR20010085857A/ko
Application granted granted Critical
Publication of KR100665204B1 publication Critical patent/KR100665204B1/ko
Assigned to 세라밴스 바이오파마 안티바이오틱스 아이피, 엘엘씨 reassignment 세라밴스 바이오파마 안티바이오틱스 아이피, 엘엘씨 권리의 전부이전등록 Assignors: 세라밴스 인코포레이티드
Assigned to 큠버랜드 파마슈티컬즈 인코포레이티드 reassignment 큠버랜드 파마슈티컬즈 인코포레이티드 권리의 전부이전등록 Assignors: 세라밴스 바이오파마 안티바이오틱스 아이피, 엘엘씨
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020017003918A 1998-12-23 1999-12-22 글리코펩티드 유도체 및 그를 포함하는 약학적 조성물 Expired - Lifetime KR100665204B1 (ko)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US11372898P 1998-12-23 1998-12-23
US60/113,728 1998-12-23
US12931399P 1999-04-14 1999-04-14
US60/129,313 1999-04-14
US16402499P 1999-11-04 1999-11-04
US60/164,024 1999-11-04
US16997899P 1999-12-10 1999-12-10
US60/169,978 1999-12-10

Publications (2)

Publication Number Publication Date
KR20010085857A KR20010085857A (ko) 2001-09-07
KR100665204B1 true KR100665204B1 (ko) 2007-01-04

Family

ID=27493926

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020017003918A Expired - Lifetime KR100665204B1 (ko) 1998-12-23 1999-12-22 글리코펩티드 유도체 및 그를 포함하는 약학적 조성물

Country Status (23)

Country Link
US (9) US6392012B1 (https=)
EP (1) EP1140993B1 (https=)
JP (1) JP4362017B2 (https=)
KR (1) KR100665204B1 (https=)
CN (1) CN1249081C (https=)
AT (1) ATE242783T1 (https=)
AU (1) AU768204B2 (https=)
BR (1) BRPI9914221B8 (https=)
CA (1) CA2336445C (https=)
CZ (1) CZ301184B6 (https=)
DE (1) DE69908819T2 (https=)
DK (1) DK1140993T3 (https=)
ES (1) ES2201825T3 (https=)
HK (1) HK1040721B (https=)
HU (1) HU230190B1 (https=)
IL (2) IL140093A0 (https=)
NO (1) NO326066B1 (https=)
NZ (1) NZ508594A (https=)
PL (1) PL198311B1 (https=)
PT (1) PT1140993E (https=)
SI (1) SI1140993T1 (https=)
WO (1) WO2000039156A1 (https=)
ZA (1) ZA200007222B (https=)

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US6518243B1 (en) * 1999-04-02 2003-02-11 Trustees Of Princeton University Desleucyl glycopeptide antibiotics and methods of making same
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CA2726789A1 (en) 2000-02-05 2001-11-08 Theravance, Inc. Cyclodextrin containing glycopeptide antibiotic compositions
AU2001259298A1 (en) 2000-05-02 2001-11-12 Advanced Medicine, Inc. Polyacid glycopeptide derivatives
JP4713810B2 (ja) 2000-05-02 2011-06-29 セラヴァンス， インコーポレーテッド グリコペプチドに対する還元的アルキル化プロセス
ES2302733T3 (es) * 2000-06-22 2008-08-01 Theravance, Inc. Derivados carboxi-sacaridos de glucopeptido.
WO2001098329A1 (en) * 2000-06-22 2001-12-27 Theravance, Inc. Polyhydroxy glycopeptide derivatives
UA75083C2 (uk) 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів
US6872804B2 (en) 2000-06-22 2005-03-29 Theravance, Inc. Glycopeptide disulfide and thioester derivatives
US6905669B2 (en) * 2001-04-24 2005-06-14 Supergen, Inc. Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
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TWI312785B (en) * 2001-08-24 2009-08-01 Theravance Inc Process for preparing vancomycin derivatives
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TWI335332B (en) 2001-10-12 2011-01-01 Theravance Inc Cross-linked vancomycin-cephalosporin antibiotics
CN101404986B (zh) 2002-05-17 2011-09-28 赛奎拉公司 用于诊断和治疗感染性疾病的组合物和制药方法
US20040033986A1 (en) 2002-05-17 2004-02-19 Protopopova Marina Nikolaevna Anti tubercular drug: compositions and methods
TWI325323B (en) * 2002-05-24 2010-06-01 Theravance Inc Cross-linked glycopeptide-cephalosporin antibiotics
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BRPI0312654A2 (pt) * 2002-07-09 2017-05-02 Fasgen Llc métodos de tratar infecções microbianas em seres humanos e animais
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US20060074014A1 (en) * 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
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US7368422B2 (en) * 2005-02-28 2008-05-06 Novartis Vaccines And Diagnostics Inc. Semi-synthetic rearranged vancomycin/desmethyl-vancomycin-based glycopeptides with antibiotic activity
US20070185015A1 (en) * 2005-02-28 2007-08-09 Chiron Corporation and North China Pharmaceutical Corporation Semi-synthetic desmethyl-vancomycin-based glycopeptides with antibiotic activity
JP5178520B2 (ja) 2005-09-22 2013-04-10 メディバス エルエルシー 固体ポリマー送達組成物およびその使用法
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KR102237887B1 (ko) 2013-03-15 2021-04-07 멜린타 서브시디어리 코프. 항생제를 사용하여 과체중 및 비만 환자에서 감염을 치료하는 방법
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CN107325159A (zh) * 2016-04-29 2017-11-07 中国科学院上海药物研究所 一类万古霉素衍生物、其制备方法、药物组合物和用途
IL270685B (en) * 2017-05-22 2022-09-01 Insmed Inc Cleavable derivatives of lipoglycopeptide and their uses
CN107987131B (zh) * 2017-11-16 2021-03-09 上海来益生物药物研究开发中心有限责任公司 一组具有抗耐药性细菌活性的化合物、其制备方法和应用
CN108409837B (zh) 2018-03-06 2021-09-24 上海来益生物药物研究开发中心有限责任公司 一组具有抗耐药性细菌活性的糖肽类化合物、其制备方法和应用
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CN114213284B (zh) * 2022-01-04 2023-08-01 丽珠集团福州福兴医药有限公司 (9h-芴-9-基)-癸基(2-氧代乙基)氨基甲酸甲酯及其合成方法
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Also Published As

Publication number Publication date
US7723470B2 (en) 2010-05-25
CA2336445A1 (en) 2000-07-06
NO20006323D0 (no) 2000-12-12
WO2000039156A1 (en) 2000-07-06
EP1140993A1 (en) 2001-10-10
ES2201825T3 (es) 2004-03-16
US6444786B1 (en) 2002-09-03
IL140093A (en) 2006-06-11
BR9914221B1 (pt) 2013-12-31
US20090215982A1 (en) 2009-08-27
BR9914221A (pt) 2001-06-26
CN1249081C (zh) 2006-04-05
US20040204346A1 (en) 2004-10-14
NO20006323L (no) 2001-02-12
IL140093A0 (en) 2002-02-10
BRPI9914221B8 (pt) 2021-05-25
US6962970B2 (en) 2005-11-08
DE69908819D1 (de) 2003-07-17
US20080103292A1 (en) 2008-05-01
US20060241024A1 (en) 2006-10-26
HUP0400887A3 (en) 2012-09-28
HU230190B1 (hu) 2015-09-28
US20050239690A1 (en) 2005-10-27
CZ301184B6 (cs) 2009-12-02
ATE242783T1 (de) 2003-06-15
US6392012B1 (en) 2002-05-21
DK1140993T3 (da) 2003-10-06
SI1140993T1 (en) 2003-12-31
US8030445B2 (en) 2011-10-04
CN1315961A (zh) 2001-10-03
PL198311B1 (pl) 2008-06-30
US20030060598A1 (en) 2003-03-27
HUP0400887A2 (hu) 2004-08-30
CZ200122A3 (en) 2001-06-13
AU3127300A (en) 2000-07-31
US6455669B1 (en) 2002-09-24
EP1140993B1 (en) 2003-06-11
US7101964B2 (en) 2006-09-05
ZA200007222B (en) 2002-03-06
AU768204B2 (en) 2003-12-04
HK1040721B (en) 2003-10-17
JP4362017B2 (ja) 2009-11-11
US6949681B2 (en) 2005-09-27
NO326066B1 (no) 2008-09-08
NZ508594A (en) 2003-05-30
HK1040721A1 (en) 2002-06-21
PL348451A1 (en) 2002-05-20
CA2336445C (en) 2011-07-19
PT1140993E (pt) 2003-10-31
US7351791B2 (en) 2008-04-01
KR20010085857A (ko) 2001-09-07
JP2002533472A (ja) 2002-10-08
DE69908819T2 (de) 2004-05-06

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