CZ301184B6 - Glykopeptidový derivát a farmaceutické prostredky, které jej obsahují - Google Patents

Glykopeptidový derivát a farmaceutické prostredky, které jej obsahují Download PDF

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Publication number
CZ301184B6
CZ301184B6 CZ20010022A CZ200122A CZ301184B6 CZ 301184 B6 CZ301184 B6 CZ 301184B6 CZ 20010022 A CZ20010022 A CZ 20010022A CZ 200122 A CZ200122 A CZ 200122A CZ 301184 B6 CZ301184 B6 CZ 301184B6
Authority
CZ
Czechia
Prior art keywords
substituted
mmol
alkyl
group
groups
Prior art date
Application number
CZ20010022A
Other languages
Czech (cs)
English (en)
Other versions
CZ200122A3 (en
Inventor
Kevin Judice@J.
Ross Fatheree@Paul
M. T. Lam@Bernice
Leadbetter@Michael
Sheringham Linsell@Martin
Mu@YongQi
Gary Trapp@Sean
Yang@Guang
Zhu@Yan
Original Assignee
Theravance, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theravance, Inc. filed Critical Theravance, Inc.
Publication of CZ200122A3 publication Critical patent/CZ200122A3/cs
Publication of CZ301184B6 publication Critical patent/CZ301184B6/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CZ20010022A 1998-12-23 1999-12-22 Glykopeptidový derivát a farmaceutické prostredky, které jej obsahují CZ301184B6 (cs)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11372898P 1998-12-23 1998-12-23
US12931399P 1999-04-14 1999-04-14
US16402499P 1999-11-04 1999-11-04
US16997899P 1999-12-10 1999-12-10

Publications (2)

Publication Number Publication Date
CZ200122A3 CZ200122A3 (en) 2001-06-13
CZ301184B6 true CZ301184B6 (cs) 2009-12-02

Family

ID=27493926

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ20010022A CZ301184B6 (cs) 1998-12-23 1999-12-22 Glykopeptidový derivát a farmaceutické prostredky, které jej obsahují

Country Status (23)

Country Link
US (9) US6392012B1 (https=)
EP (1) EP1140993B1 (https=)
JP (1) JP4362017B2 (https=)
KR (1) KR100665204B1 (https=)
CN (1) CN1249081C (https=)
AT (1) ATE242783T1 (https=)
AU (1) AU768204B2 (https=)
BR (1) BRPI9914221B8 (https=)
CA (1) CA2336445C (https=)
CZ (1) CZ301184B6 (https=)
DE (1) DE69908819T2 (https=)
DK (1) DK1140993T3 (https=)
ES (1) ES2201825T3 (https=)
HK (1) HK1040721B (https=)
HU (1) HU230190B1 (https=)
IL (2) IL140093A0 (https=)
NO (1) NO326066B1 (https=)
NZ (1) NZ508594A (https=)
PL (1) PL198311B1 (https=)
PT (1) PT1140993E (https=)
SI (1) SI1140993T1 (https=)
WO (1) WO2000039156A1 (https=)
ZA (1) ZA200007222B (https=)

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PT1140993E (pt) * 1998-12-23 2003-10-31 Theravance Inc Derivados de glicopeptidos e composicoes farmaceuticas contendo os mesmos
US6518243B1 (en) * 1999-04-02 2003-02-11 Trustees Of Princeton University Desleucyl glycopeptide antibiotics and methods of making same
US6699836B2 (en) * 1999-04-02 2004-03-02 The Trustees Of Princeton University Vancomycin analogs
AU2001238020A1 (en) * 2000-02-04 2001-08-14 Advanced Medicine, Inc. Glycopeptide derivatives having antibiotic activity
CA2726789A1 (en) 2000-02-05 2001-11-08 Theravance, Inc. Cyclodextrin containing glycopeptide antibiotic compositions
AU2001259298A1 (en) 2000-05-02 2001-11-12 Advanced Medicine, Inc. Polyacid glycopeptide derivatives
JP4713810B2 (ja) 2000-05-02 2011-06-29 セラヴァンス， インコーポレーテッド グリコペプチドに対する還元的アルキル化プロセス
ES2302733T3 (es) * 2000-06-22 2008-08-01 Theravance, Inc. Derivados carboxi-sacaridos de glucopeptido.
WO2001098329A1 (en) * 2000-06-22 2001-12-27 Theravance, Inc. Polyhydroxy glycopeptide derivatives
UA75083C2 (uk) 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів
US6872804B2 (en) 2000-06-22 2005-03-29 Theravance, Inc. Glycopeptide disulfide and thioester derivatives
US6905669B2 (en) * 2001-04-24 2005-06-14 Supergen, Inc. Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
TWI275594B (en) * 2001-08-24 2007-03-11 Theravance Inc Process for preparing vancomycin phosphonate derivatives
TWI312785B (en) * 2001-08-24 2009-08-01 Theravance Inc Process for preparing vancomycin derivatives
ATE322975T1 (de) 2001-09-19 2006-04-15 Procter & Gamble Farbbedruckte mehrschichtstruktur, ein damit hergestellter absorbierender artikel und verfahren zu deren herstellung
TWI335332B (en) 2001-10-12 2011-01-01 Theravance Inc Cross-linked vancomycin-cephalosporin antibiotics
CN101404986B (zh) 2002-05-17 2011-09-28 赛奎拉公司 用于诊断和治疗感染性疾病的组合物和制药方法
US20040033986A1 (en) 2002-05-17 2004-02-19 Protopopova Marina Nikolaevna Anti tubercular drug: compositions and methods
TWI325323B (en) * 2002-05-24 2010-06-01 Theravance Inc Cross-linked glycopeptide-cephalosporin antibiotics
AU2003243574A1 (en) 2002-06-17 2003-12-31 Theravance, Inc. PROCESS FOR PREPARING N-PROTECTED Beta-AMINO ALDEHYDE COMPOUNDS
BRPI0312654A2 (pt) * 2002-07-09 2017-05-02 Fasgen Llc métodos de tratar infecções microbianas em seres humanos e animais
MXPA05005338A (es) * 2002-11-18 2005-12-14 Vicuron Pharm Inc Metodos para administrar dalbavancin para el tratamiento de infecciones bacterianas.
US20060074014A1 (en) * 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
JP2007500222A (ja) 2003-05-23 2007-01-11 セラヴァンス インコーポレーテッド 架橋グリコペプチド−セファロスポリン抗生物質
DE602004012269T2 (de) * 2003-07-11 2009-04-30 Theravance, Inc., South San Francisco Quervernetzte glycopeptid-cephalosporin-antibiotika
DE102004055582A1 (de) 2004-11-18 2006-05-24 Bayer Cropscience Ag N-Heterocyclyl-phthalsäurediamide
US8778874B2 (en) 2004-11-29 2014-07-15 National University Corporation Nagoya University Glycopeptide antibiotic monomer derivatives
US8304597B2 (en) 2004-12-15 2012-11-06 The Procter And Gamble Company Method of using an absorbent article having a functional enhancement indicator
US7632918B2 (en) * 2005-02-28 2009-12-15 Novartis Vaccines And Diagnostics, Inc. Semi-synthetic glycopeptides with antibiotic activity
US7368422B2 (en) * 2005-02-28 2008-05-06 Novartis Vaccines And Diagnostics Inc. Semi-synthetic rearranged vancomycin/desmethyl-vancomycin-based glycopeptides with antibiotic activity
US20070185015A1 (en) * 2005-02-28 2007-08-09 Chiron Corporation and North China Pharmaceutical Corporation Semi-synthetic desmethyl-vancomycin-based glycopeptides with antibiotic activity
JP5178520B2 (ja) 2005-09-22 2013-04-10 メディバス エルエルシー 固体ポリマー送達組成物およびその使用法
CA2623198C (en) 2005-09-22 2014-08-05 Medivas, Llc Bis-(a-amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use
WO2007084507A2 (en) * 2006-01-13 2007-07-26 The Scripps Research Institute [ψ[CH2NH]PG4] GLYCOPEPTIDE ANTIBIOTIC ANALOGS
TW200808818A (en) * 2006-05-26 2008-02-16 Shionogi & Co Glycopeptide antibiotic derivatives
CA2710602A1 (en) * 2007-12-26 2009-07-09 Lead Therapeutics, Inc. Novel semi-synthetic glycopeptides as antibacterial agents
CN101959900A (zh) 2007-12-26 2011-01-26 盐野义制药株式会社 糖肽类抗生素糖基化衍生物
EP2260060A4 (en) 2008-04-01 2013-01-16 Univ Cornell ORGANIC SOLUBLE CHITOSA SALT AND CHITOSAN DERIVED BIOMATERIALS MANUFACTURED THEREFROM
GB2465863A (en) * 2008-12-05 2010-06-09 Lead Therapeutics Inc Semi-synthetic heptapeptidic glycopeptides for the treatment of bacterial infections
CN101928330B (zh) * 2009-06-26 2013-10-16 上海来益生物药物研究开发中心有限责任公司 一种新的化合物及其应用
WO2012129493A1 (en) * 2011-03-24 2012-09-27 Seachaid Pharmaceuticals, Inc. Vancomycin derivatives
KR102237887B1 (ko) 2013-03-15 2021-04-07 멜린타 서브시디어리 코프. 항생제를 사용하여 과체중 및 비만 환자에서 감염을 치료하는 방법
AU2014322817A1 (en) * 2013-09-23 2016-04-21 Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) Vancomycin-sugar conjugates and uses thereof
WO2016103284A1 (en) * 2014-12-25 2016-06-30 Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) Glycopeptides and uses thereof
CA3011208A1 (en) * 2016-01-15 2017-07-20 Universitat Hamburg Methods for the production of rhamnosylated flavonoids
US10696698B2 (en) * 2016-01-28 2020-06-30 ACatechol, Inc. Surface primer compositions and methods of use
CN107325159A (zh) * 2016-04-29 2017-11-07 中国科学院上海药物研究所 一类万古霉素衍生物、其制备方法、药物组合物和用途
IL270685B (en) * 2017-05-22 2022-09-01 Insmed Inc Cleavable derivatives of lipoglycopeptide and their uses
CN107987131B (zh) * 2017-11-16 2021-03-09 上海来益生物药物研究开发中心有限责任公司 一组具有抗耐药性细菌活性的化合物、其制备方法和应用
CN108409837B (zh) 2018-03-06 2021-09-24 上海来益生物药物研究开发中心有限责任公司 一组具有抗耐药性细菌活性的糖肽类化合物、其制备方法和应用
NL2023883B1 (en) * 2019-09-24 2021-04-26 Univ Leiden Antibiotic compounds
CN111620931B (zh) * 2020-06-12 2021-12-17 苏州博源医疗科技有限公司 万古霉素衍生物及其制备方法和应用
CN114213284B (zh) * 2022-01-04 2023-08-01 丽珠集团福州福兴医药有限公司 (9h-芴-9-基)-癸基(2-氧代乙基)氨基甲酸甲酯及其合成方法
CN121270649A (zh) * 2024-07-03 2026-01-06 烟台新药创制山东省实验室 一类万古霉素衍生物、其制备方法、药物组合物和用途

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Also Published As

Publication number Publication date
US7723470B2 (en) 2010-05-25
CA2336445A1 (en) 2000-07-06
NO20006323D0 (no) 2000-12-12
WO2000039156A1 (en) 2000-07-06
EP1140993A1 (en) 2001-10-10
ES2201825T3 (es) 2004-03-16
US6444786B1 (en) 2002-09-03
IL140093A (en) 2006-06-11
BR9914221B1 (pt) 2013-12-31
US20090215982A1 (en) 2009-08-27
BR9914221A (pt) 2001-06-26
CN1249081C (zh) 2006-04-05
US20040204346A1 (en) 2004-10-14
NO20006323L (no) 2001-02-12
IL140093A0 (en) 2002-02-10
BRPI9914221B8 (pt) 2021-05-25
US6962970B2 (en) 2005-11-08
DE69908819D1 (de) 2003-07-17
US20080103292A1 (en) 2008-05-01
US20060241024A1 (en) 2006-10-26
HUP0400887A3 (en) 2012-09-28
HU230190B1 (hu) 2015-09-28
US20050239690A1 (en) 2005-10-27
ATE242783T1 (de) 2003-06-15
US6392012B1 (en) 2002-05-21
DK1140993T3 (da) 2003-10-06
SI1140993T1 (en) 2003-12-31
US8030445B2 (en) 2011-10-04
CN1315961A (zh) 2001-10-03
PL198311B1 (pl) 2008-06-30
US20030060598A1 (en) 2003-03-27
HUP0400887A2 (hu) 2004-08-30
CZ200122A3 (en) 2001-06-13
AU3127300A (en) 2000-07-31
US6455669B1 (en) 2002-09-24
EP1140993B1 (en) 2003-06-11
US7101964B2 (en) 2006-09-05
ZA200007222B (en) 2002-03-06
AU768204B2 (en) 2003-12-04
HK1040721B (en) 2003-10-17
JP4362017B2 (ja) 2009-11-11
US6949681B2 (en) 2005-09-27
NO326066B1 (no) 2008-09-08
NZ508594A (en) 2003-05-30
HK1040721A1 (en) 2002-06-21
PL348451A1 (en) 2002-05-20
CA2336445C (en) 2011-07-19
PT1140993E (pt) 2003-10-31
US7351791B2 (en) 2008-04-01
KR20010085857A (ko) 2001-09-07
JP2002533472A (ja) 2002-10-08
DE69908819T2 (de) 2004-05-06
KR100665204B1 (ko) 2007-01-04

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