ATE242783T1 - Glycopeptid-derivate und pharmazeutische zusammensetzungen, die sie enthalten - Google Patents

Glycopeptid-derivate und pharmazeutische zusammensetzungen, die sie enthalten

Info

Publication number
ATE242783T1
ATE242783T1 AT99965331T AT99965331T ATE242783T1 AT E242783 T1 ATE242783 T1 AT E242783T1 AT 99965331 T AT99965331 T AT 99965331T AT 99965331 T AT99965331 T AT 99965331T AT E242783 T1 ATE242783 T1 AT E242783T1
Authority
AT
Austria
Prior art keywords
pharmaceutical compositions
compositions containing
derivatives
glycopeptide
glycopeptide derivatives
Prior art date
Application number
AT99965331T
Other languages
English (en)
Inventor
J Kevin Judice
Paul Ross Fatheree
Bernice M T Lam
Michael Leadbetter
Martin Sheringham Linsell
Yongqi Mu
Sean Gary Trapp
Guang Yang
Yan Zhu
Original Assignee
Theravance Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theravance Inc filed Critical Theravance Inc
Application granted granted Critical
Publication of ATE242783T1 publication Critical patent/ATE242783T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT99965331T 1998-12-23 1999-12-22 Glycopeptid-derivate und pharmazeutische zusammensetzungen, die sie enthalten ATE242783T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11372898P 1998-12-23 1998-12-23
US12931399P 1999-04-14 1999-04-14
US16402499P 1999-11-04 1999-11-04
US16997899P 1999-12-10 1999-12-10
PCT/US1999/030543 WO2000039156A1 (en) 1998-12-23 1999-12-22 Glycopeptide derivatives and pharmaceutical compositions containing the same

Publications (1)

Publication Number Publication Date
ATE242783T1 true ATE242783T1 (de) 2003-06-15

Family

ID=27493926

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99965331T ATE242783T1 (de) 1998-12-23 1999-12-22 Glycopeptid-derivate und pharmazeutische zusammensetzungen, die sie enthalten

Country Status (23)

Country Link
US (9) US6392012B1 (de)
EP (1) EP1140993B1 (de)
JP (1) JP4362017B2 (de)
KR (1) KR100665204B1 (de)
CN (1) CN1249081C (de)
AT (1) ATE242783T1 (de)
AU (1) AU768204B2 (de)
BR (1) BRPI9914221B8 (de)
CA (1) CA2336445C (de)
CZ (1) CZ301184B6 (de)
DE (1) DE69908819T2 (de)
DK (1) DK1140993T3 (de)
ES (1) ES2201825T3 (de)
HK (1) HK1040721B (de)
HU (1) HU230190B1 (de)
IL (2) IL140093A0 (de)
NO (1) NO326066B1 (de)
NZ (1) NZ508594A (de)
PL (1) PL198311B1 (de)
PT (1) PT1140993E (de)
SI (1) SI1140993T1 (de)
WO (1) WO2000039156A1 (de)
ZA (1) ZA200007222B (de)

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ATE242783T1 (de) * 1998-12-23 2003-06-15 Theravance Inc Glycopeptid-derivate und pharmazeutische zusammensetzungen, die sie enthalten
US6699836B2 (en) * 1999-04-02 2004-03-02 The Trustees Of Princeton University Vancomycin analogs
US6518243B1 (en) * 1999-04-02 2003-02-11 Trustees Of Princeton University Desleucyl glycopeptide antibiotics and methods of making same
AU2001238020A1 (en) * 2000-02-04 2001-08-14 Advanced Medicine, Inc. Glycopeptide derivatives having antibiotic activity
JP4713810B2 (ja) 2000-05-02 2011-06-29 セラヴァンス, インコーポレーテッド グリコペプチドに対する還元的アルキル化プロセス
US6770621B2 (en) * 2000-05-02 2004-08-03 Theravance, Inc. Polyacid glycopeptide derivatives
EP1278549B1 (de) 2000-05-02 2008-12-10 Theravance, Inc. Zusammensetzung die eine zyklodextrin und ein glykopeptid-antibiotikum enthält
US6872804B2 (en) 2000-06-22 2005-03-29 Theravance, Inc. Glycopeptide disulfide and thioester derivatives
US6828299B2 (en) 2000-06-22 2004-12-07 Theravance, Inc. Polyhydroxy glycopeptide derivatives
UA75083C2 (uk) * 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів
ATE388960T1 (de) * 2000-06-22 2008-03-15 Theravance Inc Glykopeptidderivate mit carboxysacchariden
US6905669B2 (en) * 2001-04-24 2005-06-14 Supergen, Inc. Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
TWI312785B (en) 2001-08-24 2009-08-01 Theravance Inc Process for preparing vancomycin derivatives
TWI275594B (en) * 2001-08-24 2007-03-11 Theravance Inc Process for preparing vancomycin phosphonate derivatives
DE60118737T2 (de) 2001-09-19 2006-10-19 The Procter & Gamble Company, Cincinnati Farbbedruckte Mehrschichtstruktur, ein damit hergestellter absorbierender Artikel und Verfahren zu deren Herstellung
TWI335332B (en) 2001-10-12 2011-01-01 Theravance Inc Cross-linked vancomycin-cephalosporin antibiotics
US20040033986A1 (en) 2002-05-17 2004-02-19 Protopopova Marina Nikolaevna Anti tubercular drug: compositions and methods
CN101404986B (zh) 2002-05-17 2011-09-28 赛奎拉公司 用于诊断和治疗感染性疾病的组合物和制药方法
WO2003099858A1 (en) 2002-05-24 2003-12-04 Theravance, Inc. Cross-linked glycopeptide-cephalosporin antibiotics
WO2003106399A2 (en) 2002-06-17 2003-12-24 Theravance, Inc. PROCESS FOR PREPARING N-PROTECTED β-AMINO ALDEHYDE COMPOUNDS
KR20050047519A (ko) * 2002-07-09 2005-05-20 파스젠, 엘엘씨. 사람 및 동물에서의 미생물 감염의 치료방법
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US20060074014A1 (en) * 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
DE602004024393D1 (de) 2003-05-23 2010-01-14 Theravance Inc Quervernetzte glycopeptid-cephalosporin-antibiotika
US7067482B2 (en) 2003-07-11 2006-06-27 Theravance, Inc. Cross-linked glycopeptide-cephalosporin antibiotics
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US8778874B2 (en) 2004-11-29 2014-07-15 National University Corporation Nagoya University Glycopeptide antibiotic monomer derivatives
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US7632918B2 (en) * 2005-02-28 2009-12-15 Novartis Vaccines And Diagnostics, Inc. Semi-synthetic glycopeptides with antibiotic activity
US7368422B2 (en) * 2005-02-28 2008-05-06 Novartis Vaccines And Diagnostics Inc. Semi-synthetic rearranged vancomycin/desmethyl-vancomycin-based glycopeptides with antibiotic activity
US20070185015A1 (en) * 2005-02-28 2007-08-09 Chiron Corporation and North China Pharmaceutical Corporation Semi-synthetic desmethyl-vancomycin-based glycopeptides with antibiotic activity
JP5178520B2 (ja) 2005-09-22 2013-04-10 メディバス エルエルシー 固体ポリマー送達組成物およびその使用法
EP1926780B1 (de) 2005-09-22 2013-08-14 Medivas, LLC Bis-( -amino)-diol-diester-haltige poly(esteramid) und poly(esterurethan)-zusammensetzungen und verwendungsverfahren
WO2007084507A2 (en) * 2006-01-13 2007-07-26 The Scripps Research Institute [ψ[CH2NH]PG4] GLYCOPEPTIDE ANTIBIOTIC ANALOGS
TW200808818A (en) 2006-05-26 2008-02-16 Shionogi & Co Glycopeptide antibiotic derivatives
KR20100109936A (ko) * 2007-12-26 2010-10-11 리드 테라퓨틱스, 인크. 항박테리아제로서의 신규한 반(半)-합성 글리코펩티드
KR20100109934A (ko) 2007-12-26 2010-10-11 시오노기세야쿠 가부시키가이샤 글리코펩티드 항생 물질 배당화 유도체
US8841440B2 (en) 2008-04-01 2014-09-23 Cornell University Organo-soluble chitosan salts and chitosan-derived biomaterials prepared thereof
GB2465863A (en) * 2008-12-05 2010-06-09 Lead Therapeutics Inc Semi-synthetic heptapeptidic glycopeptides for the treatment of bacterial infections
CN101928330B (zh) * 2009-06-26 2013-10-16 上海来益生物药物研究开发中心有限责任公司 一种新的化合物及其应用
EP2688580A4 (de) * 2011-03-24 2015-03-25 Seachaid Pharmaceuticals Inc Vancomycinderivate
EP2969004B1 (de) 2013-03-15 2026-02-25 Melinta Subsidiary Corp. Delafloxacin zur verwending in der behandlung von infektionen bei adipösen patienten
CA2925005A1 (en) * 2013-09-23 2015-03-26 Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) Vancomycin-sugar conjugates and uses thereof
US20170342110A1 (en) * 2014-12-25 2017-11-30 Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) Glycopeptides and uses thereof
CN109072271A (zh) * 2016-01-15 2018-12-21 汉堡大学 用于制备鼠李糖基化类黄酮的方法
WO2017132484A1 (en) * 2016-01-28 2017-08-03 ACatechol, Inc. Photo-cleavable primer compositions and methods of use
CN107325159A (zh) * 2016-04-29 2017-11-07 中国科学院上海药物研究所 一类万古霉素衍生物、其制备方法、药物组合物和用途
IL270685B (en) 2017-05-22 2022-09-01 Insmed Inc Cleavable derivatives of lipoglycopeptide and their uses
CN107987131B (zh) * 2017-11-16 2021-03-09 上海来益生物药物研究开发中心有限责任公司 一组具有抗耐药性细菌活性的化合物、其制备方法和应用
CN108409837B (zh) 2018-03-06 2021-09-24 上海来益生物药物研究开发中心有限责任公司 一组具有抗耐药性细菌活性的糖肽类化合物、其制备方法和应用
NL2023883B1 (en) * 2019-09-24 2021-04-26 Univ Leiden Antibiotic compounds
CN111620931B (zh) * 2020-06-12 2021-12-17 苏州博源医疗科技有限公司 万古霉素衍生物及其制备方法和应用
CN114213284B (zh) * 2022-01-04 2023-08-01 丽珠集团福州福兴医药有限公司 (9h-芴-9-基)-癸基(2-氧代乙基)氨基甲酸甲酯及其合成方法

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Also Published As

Publication number Publication date
NO326066B1 (no) 2008-09-08
KR100665204B1 (ko) 2007-01-04
HUP0400887A2 (hu) 2004-08-30
US6455669B1 (en) 2002-09-24
NO20006323D0 (no) 2000-12-12
WO2000039156A1 (en) 2000-07-06
CN1315961A (zh) 2001-10-03
PT1140993E (pt) 2003-10-31
CZ301184B6 (cs) 2009-12-02
ES2201825T3 (es) 2004-03-16
BRPI9914221B8 (pt) 2021-05-25
JP4362017B2 (ja) 2009-11-11
EP1140993B1 (de) 2003-06-11
BR9914221B1 (pt) 2013-12-31
KR20010085857A (ko) 2001-09-07
US20060241024A1 (en) 2006-10-26
PL198311B1 (pl) 2008-06-30
CZ200122A3 (en) 2001-06-13
CA2336445A1 (en) 2000-07-06
DE69908819T2 (de) 2004-05-06
EP1140993A1 (de) 2001-10-10
HUP0400887A3 (en) 2012-09-28
US20040204346A1 (en) 2004-10-14
US6444786B1 (en) 2002-09-03
IL140093A0 (en) 2002-02-10
HK1040721A1 (en) 2002-06-21
HK1040721B (en) 2003-10-17
AU768204B2 (en) 2003-12-04
US20030060598A1 (en) 2003-03-27
NZ508594A (en) 2003-05-30
US7351791B2 (en) 2008-04-01
US6949681B2 (en) 2005-09-27
US20090215982A1 (en) 2009-08-27
HU230190B1 (hu) 2015-09-28
NO20006323L (no) 2001-02-12
AU3127300A (en) 2000-07-31
IL140093A (en) 2006-06-11
JP2002533472A (ja) 2002-10-08
CN1249081C (zh) 2006-04-05
US7723470B2 (en) 2010-05-25
CA2336445C (en) 2011-07-19
US20080103292A1 (en) 2008-05-01
DK1140993T3 (da) 2003-10-06
US7101964B2 (en) 2006-09-05
ZA200007222B (en) 2002-03-06
SI1140993T1 (en) 2003-12-31
US6392012B1 (en) 2002-05-21
US20050239690A1 (en) 2005-10-27
BR9914221A (pt) 2001-06-26
US6962970B2 (en) 2005-11-08
US8030445B2 (en) 2011-10-04
PL348451A1 (en) 2002-05-20
DE69908819D1 (de) 2003-07-17

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