NO20006323L - Glykopeptid-derivater og farmasöytiske sammensetninger som inneholder disse - Google Patents

Glykopeptid-derivater og farmasöytiske sammensetninger som inneholder disse

Info

Publication number
NO20006323L
NO20006323L NO20006323A NO20006323A NO20006323L NO 20006323 L NO20006323 L NO 20006323L NO 20006323 A NO20006323 A NO 20006323A NO 20006323 A NO20006323 A NO 20006323A NO 20006323 L NO20006323 L NO 20006323L
Authority
NO
Norway
Prior art keywords
pharmaceutical compositions
compositions containing
derivatives
glycopeptide
glycopeptide derivatives
Prior art date
Application number
NO20006323A
Other languages
English (en)
Other versions
NO326066B1 (no
NO20006323D0 (no
Inventor
J Kevin Judice
Paul Ross Fatheree
Bernice M T Lam
Michael R Leadbetter
Martin Sheringham Linsell
Yongqi Mu
Sean Gary Trapp
Guang Yang
Yan Zhu
Original Assignee
Advanced Medicine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Medicine Inc filed Critical Advanced Medicine Inc
Publication of NO20006323D0 publication Critical patent/NO20006323D0/no
Publication of NO20006323L publication Critical patent/NO20006323L/no
Publication of NO326066B1 publication Critical patent/NO326066B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20006323A 1998-12-23 2000-12-12 Glykopeptid-derivater, farmasøytiske sammensetninger samt anvendelser derav. NO326066B1 (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11372898P 1998-12-23 1998-12-23
US12931399P 1999-04-14 1999-04-14
US16402499P 1999-11-04 1999-11-04
US16997899P 1999-12-10 1999-12-10
PCT/US1999/030543 WO2000039156A1 (en) 1998-12-23 1999-12-22 Glycopeptide derivatives and pharmaceutical compositions containing the same

Publications (3)

Publication Number Publication Date
NO20006323D0 NO20006323D0 (no) 2000-12-12
NO20006323L true NO20006323L (no) 2001-02-12
NO326066B1 NO326066B1 (no) 2008-09-08

Family

ID=27493926

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20006323A NO326066B1 (no) 1998-12-23 2000-12-12 Glykopeptid-derivater, farmasøytiske sammensetninger samt anvendelser derav.

Country Status (23)

Country Link
US (9) US6392012B1 (no)
EP (1) EP1140993B1 (no)
JP (1) JP4362017B2 (no)
KR (1) KR100665204B1 (no)
CN (1) CN1249081C (no)
AT (1) ATE242783T1 (no)
AU (1) AU768204B2 (no)
BR (1) BRPI9914221B8 (no)
CA (1) CA2336445C (no)
CZ (1) CZ301184B6 (no)
DE (1) DE69908819T2 (no)
DK (1) DK1140993T3 (no)
ES (1) ES2201825T3 (no)
HK (1) HK1040721B (no)
HU (1) HU230190B1 (no)
IL (2) IL140093A0 (no)
NO (1) NO326066B1 (no)
NZ (1) NZ508594A (no)
PL (1) PL198311B1 (no)
PT (1) PT1140993E (no)
SI (1) SI1140993T1 (no)
WO (1) WO2000039156A1 (no)
ZA (1) ZA200007222B (no)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4362017B2 (ja) * 1998-12-23 2009-11-11 セラヴァンス, インコーポレーテッド グリコペプチド誘導体およびそれを含有する薬学的組成物
WO2000059528A1 (en) * 1999-04-02 2000-10-12 The Trustees Of Princeton University Desleucyl glycopeptide antibiotics and methods of making same
US6699836B2 (en) * 1999-04-02 2004-03-02 The Trustees Of Princeton University Vancomycin analogs
AU2001238020A1 (en) * 2000-02-04 2001-08-14 Advanced Medicine, Inc. Glycopeptide derivatives having antibiotic activity
CN100532392C (zh) 2000-05-02 2009-08-26 施万制药 还原性烷基化方法
AU2001259306A1 (en) 2000-05-02 2001-11-12 Advanced Medicine, Inc. Pharmaceutical compositions containing a glycopeptide antibiotic and a cyclodextrin
WO2001083520A2 (en) * 2000-05-02 2001-11-08 Theravance,Inc Polyacid glycopeptide derivatives
US6872804B2 (en) 2000-06-22 2005-03-29 Theravance, Inc. Glycopeptide disulfide and thioester derivatives
WO2001098329A1 (en) * 2000-06-22 2001-12-27 Theravance, Inc. Polyhydroxy glycopeptide derivatives
WO2001098327A2 (en) * 2000-06-22 2001-12-27 Theravance, Inc. Glycopeptide carboxy-saccharide derivatives
UA75083C2 (uk) 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів
US6905669B2 (en) * 2001-04-24 2005-06-14 Supergen, Inc. Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
TWI275594B (en) * 2001-08-24 2007-03-11 Theravance Inc Process for preparing vancomycin phosphonate derivatives
TWI312785B (en) * 2001-08-24 2009-08-01 Theravance Inc Process for preparing vancomycin derivatives
DE60118737T2 (de) 2001-09-19 2006-10-19 The Procter & Gamble Company, Cincinnati Farbbedruckte Mehrschichtstruktur, ein damit hergestellter absorbierender Artikel und Verfahren zu deren Herstellung
TWI335332B (en) 2001-10-12 2011-01-01 Theravance Inc Cross-linked vancomycin-cephalosporin antibiotics
CN101404986B (zh) 2002-05-17 2011-09-28 赛奎拉公司 用于诊断和治疗感染性疾病的组合物和制药方法
US20040033986A1 (en) * 2002-05-17 2004-02-19 Protopopova Marina Nikolaevna Anti tubercular drug: compositions and methods
WO2003099858A1 (en) 2002-05-24 2003-12-04 Theravance, Inc. Cross-linked glycopeptide-cephalosporin antibiotics
WO2003106399A2 (en) 2002-06-17 2003-12-24 Theravance, Inc. PROCESS FOR PREPARING N-PROTECTED β-AMINO ALDEHYDE COMPOUNDS
CA2491573A1 (en) * 2002-07-09 2004-01-15 Fasgen, Llc Methods of treating microbial infections in humans and animals
US20060074014A1 (en) * 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
KR101173310B1 (ko) * 2002-11-18 2012-08-10 비큐론 파마세티컬스 인코포레이티드 박테리아 감염 치료를 위한 달바반신 투여 방법
EP1633759B1 (en) 2003-05-23 2009-12-02 Theravance, Inc. Cross-linked glycopeptide-cephalosporin antibiotics
EP1644382B1 (en) * 2003-07-11 2008-03-05 Theravance, Inc. Cross-linked glycopeptide-cephalosporin antibiotics
DE102004055582A1 (de) * 2004-11-18 2006-05-24 Bayer Cropscience Ag N-Heterocyclyl-phthalsäurediamide
TW200626616A (en) 2004-11-29 2006-08-01 Univ Nagoya Nat Univ Corp Monomer derivatives of glycopeptide antibiotics
US8304597B2 (en) 2004-12-15 2012-11-06 The Procter And Gamble Company Method of using an absorbent article having a functional enhancement indicator
US7368422B2 (en) * 2005-02-28 2008-05-06 Novartis Vaccines And Diagnostics Inc. Semi-synthetic rearranged vancomycin/desmethyl-vancomycin-based glycopeptides with antibiotic activity
US20070185015A1 (en) * 2005-02-28 2007-08-09 Chiron Corporation and North China Pharmaceutical Corporation Semi-synthetic desmethyl-vancomycin-based glycopeptides with antibiotic activity
US7632918B2 (en) * 2005-02-28 2009-12-15 Novartis Vaccines And Diagnostics, Inc. Semi-synthetic glycopeptides with antibiotic activity
EP1926780B1 (en) 2005-09-22 2013-08-14 Medivas, LLC Bis-( -amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use
US8652504B2 (en) 2005-09-22 2014-02-18 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
US20070173438A1 (en) * 2006-01-13 2007-07-26 The Scripps Research Institute [PSI[CH2NH]PG4] glycopeptide antibiotic analogs
TW200808818A (en) * 2006-05-26 2008-02-16 Shionogi & Co Glycopeptide antibiotic derivatives
CN101959849A (zh) * 2007-12-26 2011-01-26 利德治疗公司 作为抗菌剂的新型半合成糖肽
US8481696B2 (en) 2007-12-26 2013-07-09 Shionogi & Co., Ltd. Glycosylated glycopeptide antibiotic derivatives
EP2260060A4 (en) 2008-04-01 2013-01-16 Univ Cornell ORGANIC SOLUBLE CHITOSA SALT AND CHITOSAN DERIVED BIOMATERIALS MANUFACTURED THEREFROM
GB2465863A (en) * 2008-12-05 2010-06-09 Lead Therapeutics Inc Semi-synthetic heptapeptidic glycopeptides for the treatment of bacterial infections
CN101928330B (zh) * 2009-06-26 2013-10-16 上海来益生物药物研究开发中心有限责任公司 一种新的化合物及其应用
WO2012129493A1 (en) * 2011-03-24 2012-09-27 Seachaid Pharmaceuticals, Inc. Vancomycin derivatives
WO2014152332A1 (en) 2013-03-15 2014-09-25 Melinta Therapeutics, Inc. Methods of treating infections in overweight and obese patients using antibiotics
CA2925005A1 (en) * 2013-09-23 2015-03-26 Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) Vancomycin-sugar conjugates and uses thereof
EP3240574A1 (en) * 2014-12-25 2017-11-08 Jawaharlal Nehru Centre For Advanced Scientific Research Glycopeptides and uses thereof
WO2017121863A1 (en) * 2016-01-15 2017-07-20 Universität Hamburg Methods for the production of rhamnosylated flavonoids
US10696698B2 (en) * 2016-01-28 2020-06-30 ACatechol, Inc. Surface primer compositions and methods of use
CN107325159A (zh) * 2016-04-29 2017-11-07 中国科学院上海药物研究所 一类万古霉素衍生物、其制备方法、药物组合物和用途
AU2018273887B2 (en) * 2017-05-22 2022-09-08 Insmed Incorporated Lipo-glycopeptide cleavable derivatives and uses thereof
CN107987131B (zh) * 2017-11-16 2021-03-09 上海来益生物药物研究开发中心有限责任公司 一组具有抗耐药性细菌活性的化合物、其制备方法和应用
CN108409837B (zh) 2018-03-06 2021-09-24 上海来益生物药物研究开发中心有限责任公司 一组具有抗耐药性细菌活性的糖肽类化合物、其制备方法和应用
NL2023883B1 (en) * 2019-09-24 2021-04-26 Univ Leiden Antibiotic compounds
CN111620931B (zh) * 2020-06-12 2021-12-17 苏州博源医疗科技有限公司 万古霉素衍生物及其制备方法和应用
CN114213284B (zh) * 2022-01-04 2023-08-01 丽珠集团福州福兴医药有限公司 (9h-芴-9-基)-癸基(2-氧代乙基)氨基甲酸甲酯及其合成方法

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4497802A (en) 1983-10-21 1985-02-05 Eli Lilly And Company N-Acyl glycopeptide derivatives
US4914187A (en) 1984-11-13 1990-04-03 Gruppo Lepetit S.P.A Ester derivatives of antibiotic L 17046
GB8428619D0 (en) 1984-11-13 1984-12-19 Lepetit Spa Derivatives of antibiotic l 17046
US4698327A (en) 1985-04-25 1987-10-06 Eli Lilly And Company Novel glycopeptide derivatives
US4643987A (en) 1985-08-14 1987-02-17 Eli Lilly And Company Modified glycopeptides
US4639433A (en) 1985-08-14 1987-01-27 Eli Lilly And Company Glycopeptide derivatives
GB8704847D0 (en) * 1987-03-02 1987-04-08 Lepetit Spa Substituted alkylamides of teicoplanin compounds
FR2632185B1 (fr) * 1988-06-01 1992-05-22 Rhone Poulenc Chimie Silice pour compositions dentifrices compatible notamment avec le zinc
GB8817397D0 (en) * 1988-07-21 1988-08-24 Lepetit Spa N15-alkyl & n15 n15-di-alkyl derivatives of teicoplanin antibiotics carrying functional groups on alkyl side chain
US5534420A (en) 1988-07-28 1996-07-09 Eli Lilly And Company Biotransformation of glycopeptide antibiotics
DE68925806T2 (de) * 1988-12-27 1996-09-26 Lepetit Spa C63-Amidderivate von 34-de(acetylglucosaminyl)-34-deoxy-teicoplaninen
IE64155B1 (en) 1989-03-29 1995-07-12 Lepetit Spa New substituted alkylamide derivatives of teicoplanin
NZ236393A (en) 1989-12-13 1992-05-26 Lilly Co Eli N-alkylated glycopeptide derivatives prepared from antibiotics a82846 series and pa-42867-a; pharmaceutical compositions
AU647122B2 (en) 1990-05-28 1994-03-17 Gruppo Lepetit S.P.A. C63-amide derivatives of 34-de(acetylglucosaminyl)-34-deoxy- teicoplanin and their use as medicaments against bacteria resistant to glycopeptide antibiotics
WO1992017456A1 (en) 1991-03-26 1992-10-15 Fujisawa Pharmaceutical Co., Ltd. Amino acid derivative and salt thereof
US5750509A (en) 1991-07-29 1998-05-12 Gruppo Lepetit S.P.A. Amide derivatives of antibiotic A 40926
EP0596929B1 (en) 1991-07-29 1995-07-26 GRUPPO LEPETIT S.p.A. Amide derivatives of antibiotic a 40926
RU2145609C1 (ru) 1994-01-28 2000-02-20 Эли Лилли Энд Компани Производные гликопептида или их соли, способ получения, фармацевтическая композиция
US5840684A (en) * 1994-01-28 1998-11-24 Eli Lilly And Company Glycopeptide antibiotic derivatives
IT1282586B1 (it) 1996-02-08 1998-03-31 Chemical And Biolog Ind Composizioni farmaceutiche per il trattamento biologico delle infezioni dovute a ceppi di enterococcus faecium resistenti agli
JP2000507246A (ja) 1996-03-21 2000-06-13 トランセル テクノロジーズ インク. 固体相のリポグリコペプチドライブラリー、組成物及び方法
AU2609297A (en) 1996-04-12 1997-11-07 Eli Lilly And Company Glycopeptide compounds
WO1997038702A1 (en) 1996-04-12 1997-10-23 Eli Lilly And Company Covalently-linked glycopeptide dimers
ES2165047T3 (es) 1996-04-23 2002-03-01 Biosearch Italia Spa Procedimiento quimico mejorado para preparar derivados de amida del antibiotico a 40926.
US5919756A (en) * 1996-06-28 1999-07-06 Eli Lilly And Company Amides
US5939382A (en) 1996-11-21 1999-08-17 Eli Lilly And Company Reducing agent for reductive alkylation of glycopeptide antibiotics
US5952466A (en) 1997-11-12 1999-09-14 Eli Lilly And Company Reductive alkylation of glycopeptide antibiotics
US5916873A (en) 1997-04-17 1999-06-29 Eli Lilly And Company Teicoplanin derivatives
US5977063A (en) 1997-05-20 1999-11-02 Eli Lilly And Company Alkylated hexapeptides
US5952310A (en) 1997-05-20 1999-09-14 Eli Lilly And Company Glycopeptide hexapeptides
US5919771A (en) 1997-05-20 1999-07-06 Eli Lilly And Company Urea and thiourea derivatives of glycopeptides
EP1060189A1 (en) 1998-02-20 2000-12-20 Advanced Medicine, Inc. Derivatives of glycopeptide antibacterial agents
US6518242B1 (en) 1998-02-20 2003-02-11 Theravance, Inc. Derivatives of glycopeptide antibacterial agents
CA2330619A1 (en) 1998-05-01 1999-11-11 Eli Lilly And Company N1-modified glycopeptides
WO2000004044A1 (en) 1998-07-14 2000-01-27 Princeton University Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same
JP4362017B2 (ja) * 1998-12-23 2009-11-11 セラヴァンス, インコーポレーテッド グリコペプチド誘導体およびそれを含有する薬学的組成物
UA75083C2 (uk) 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів
WO2003099858A1 (en) 2002-05-24 2003-12-04 Theravance, Inc. Cross-linked glycopeptide-cephalosporin antibiotics
EP1644382B1 (en) 2003-07-11 2008-03-05 Theravance, Inc. Cross-linked glycopeptide-cephalosporin antibiotics

Also Published As

Publication number Publication date
US6444786B1 (en) 2002-09-03
HUP0400887A3 (en) 2012-09-28
NO326066B1 (no) 2008-09-08
ES2201825T3 (es) 2004-03-16
US20090215982A1 (en) 2009-08-27
US20060241024A1 (en) 2006-10-26
CN1315961A (zh) 2001-10-03
US7351791B2 (en) 2008-04-01
PT1140993E (pt) 2003-10-31
DK1140993T3 (da) 2003-10-06
HUP0400887A2 (hu) 2004-08-30
DE69908819D1 (de) 2003-07-17
DE69908819T2 (de) 2004-05-06
IL140093A0 (en) 2002-02-10
BRPI9914221B8 (pt) 2021-05-25
US6949681B2 (en) 2005-09-27
PL198311B1 (pl) 2008-06-30
CA2336445C (en) 2011-07-19
US20080103292A1 (en) 2008-05-01
AU768204B2 (en) 2003-12-04
NZ508594A (en) 2003-05-30
HK1040721A1 (en) 2002-06-21
KR20010085857A (ko) 2001-09-07
BR9914221B1 (pt) 2013-12-31
US6962970B2 (en) 2005-11-08
US6392012B1 (en) 2002-05-21
CZ200122A3 (en) 2001-06-13
ATE242783T1 (de) 2003-06-15
NO20006323D0 (no) 2000-12-12
US20040204346A1 (en) 2004-10-14
HK1040721B (zh) 2003-10-17
US6455669B1 (en) 2002-09-24
EP1140993A1 (en) 2001-10-10
JP2002533472A (ja) 2002-10-08
WO2000039156A1 (en) 2000-07-06
JP4362017B2 (ja) 2009-11-11
SI1140993T1 (en) 2003-12-31
CZ301184B6 (cs) 2009-12-02
AU3127300A (en) 2000-07-31
CA2336445A1 (en) 2000-07-06
US20030060598A1 (en) 2003-03-27
HU230190B1 (hu) 2015-09-28
US8030445B2 (en) 2011-10-04
CN1249081C (zh) 2006-04-05
US7101964B2 (en) 2006-09-05
ZA200007222B (en) 2002-03-06
US7723470B2 (en) 2010-05-25
KR100665204B1 (ko) 2007-01-04
IL140093A (en) 2006-06-11
US20050239690A1 (en) 2005-10-27
BR9914221A (pt) 2001-06-26
EP1140993B1 (en) 2003-06-11
PL348451A1 (en) 2002-05-20

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Owner name: THERAVANCE BIOPHARMA R&D IP, US

CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: THERAVANCE BIOPHARMA ANTIBIOTICS IP, US

CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: CUMBERLAND PHARMACEUTICALS INC., US

MK1K Patent expired