NO20012727D0 - 3,4,5-trisubstituerte arylnitronforbindelser og farmasöytiske sammensetninger som inneholder samme - Google Patents

3,4,5-trisubstituerte arylnitronforbindelser og farmasöytiske sammensetninger som inneholder samme

Info

Publication number
NO20012727D0
NO20012727D0 NO20012727A NO20012727A NO20012727D0 NO 20012727 D0 NO20012727 D0 NO 20012727D0 NO 20012727 A NO20012727 A NO 20012727A NO 20012727 A NO20012727 A NO 20012727A NO 20012727 D0 NO20012727 D0 NO 20012727D0
Authority
NO
Norway
Prior art keywords
arylnitron
trisubstituted
compounds
same
pharmaceutical compositions
Prior art date
Application number
NO20012727A
Other languages
English (en)
Other versions
NO20012727L (no
Inventor
L David Waterbury
Allan Lee Wilcox
John Michael Carney
Farah Mavandadi
Albert Danielzadeh
Original Assignee
Centaur Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centaur Pharmaceuticals Inc filed Critical Centaur Pharmaceuticals Inc
Publication of NO20012727D0 publication Critical patent/NO20012727D0/no
Publication of NO20012727L publication Critical patent/NO20012727L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C291/00Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
    • C07C291/02Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
NO20012727A 1998-12-02 2001-06-01 3,4,5-trisubstituerte arylnitronforbindelser og farmasöytiske sammensetninger som inneholder samme NO20012727L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11054198P 1998-12-02 1998-12-02
PCT/US1999/028479 WO2000032567A1 (en) 1998-12-02 1999-12-01 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing the same

Publications (2)

Publication Number Publication Date
NO20012727D0 true NO20012727D0 (no) 2001-06-01
NO20012727L NO20012727L (no) 2001-07-26

Family

ID=22333591

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20012727A NO20012727L (no) 1998-12-02 2001-06-01 3,4,5-trisubstituerte arylnitronforbindelser og farmasöytiske sammensetninger som inneholder samme

Country Status (21)

Country Link
US (1) US6342523B1 (no)
EP (1) EP1135367A1 (no)
JP (1) JP2002531435A (no)
KR (1) KR20010087407A (no)
CN (1) CN1334800A (no)
AU (1) AU773343B2 (no)
BR (1) BR9915886A (no)
CA (1) CA2353402A1 (no)
CZ (1) CZ20011830A3 (no)
EA (1) EA004931B1 (no)
HK (1) HK1044147A1 (no)
HU (1) HUP0104576A3 (no)
IL (1) IL143506A0 (no)
IS (1) IS5958A (no)
NO (1) NO20012727L (no)
NZ (1) NZ512032A (no)
PL (1) PL349916A1 (no)
SK (1) SK7502001A3 (no)
UA (1) UA66401C2 (no)
WO (1) WO2000032567A1 (no)
ZA (1) ZA200104378B (no)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050107366A1 (en) * 1991-06-18 2005-05-19 Carney John M. Spin trapping pharmaceutical compositions and methods for use thereof
US6730700B2 (en) 1998-12-02 2004-05-04 Renovis, Inc. 3,4,5,-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing the same
AU2002253857A1 (en) * 2001-01-08 2002-09-04 Centaur Pharmaceuticals, Inc. Use of aryl nitrone compounds in methods for treating neuropathic pain
US20030045461A1 (en) * 2001-09-06 2003-03-06 Jen-Chang Hsia Composition and methods of esterified nitroxides gated with carboxylic acids
TW200404069A (en) * 2002-06-28 2004-03-16 Upjohn Co Difluorothioacetamides of oxazolidinones with a glycoloylpiperazine substituent
TW200403240A (en) * 2002-06-28 2004-03-01 Upjohn Co Difluorothioacetamides of oxazolidinones as antibacterial agents
US7115666B2 (en) * 2002-10-15 2006-10-03 Renovis, Inc. Nitrone compounds, pharmaceutical compositions containing the same and methods for treating inflammation and neuropathic pain
US20050059638A1 (en) * 2003-08-04 2005-03-17 Kelly Michael G. Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders
US20050182060A1 (en) * 2004-02-13 2005-08-18 Kelly Michael G. 2-Substituted and 4-substituted aryl nitrone compounds
WO2005087214A1 (en) * 2004-03-09 2005-09-22 Renovis, Inc. Methods for treating multiple sclerosis and pharmaceutical compositions therefor
AU2009214727B2 (en) 2008-02-12 2014-12-11 Tosk, Incorporated Doxorubicin adjuvants to reduce toxicity and methods for using the same
CN101468970B (zh) * 2008-04-25 2011-05-11 暨南大学 一种硝酮类化合物及其制备方法和在制药中的应用
CN102311396B (zh) * 2010-07-05 2015-01-07 暨南大学 一种吡嗪类衍生物和其制备方法及在制药中的应用
US9156862B2 (en) 2011-11-01 2015-10-13 The Florida International University Board Of Trustees Silylated azulenyl nitrone spin traps as chromotropic superoxide detectors
CN104803880B (zh) * 2014-01-23 2017-11-21 广州喜鹊医药有限公司 一种具有神经保护作用的化合物及其制备方法和应用
CN109438288B (zh) * 2018-10-22 2021-05-07 河南中医药大学 一种n-硝酮取代芳香酰胺衍生物及其制备方法
CA3209491A1 (en) 2021-03-15 2022-09-22 Saul Yedgar Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory disease

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4224340A (en) 1977-10-06 1980-09-23 William H. Rorer, Inc. Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds
GB2137619A (en) 1983-03-30 1984-10-10 Gerald Scott Nitrone compounds and stabilised rubber compositions containing them
GB8813339D0 (en) * 1988-06-06 1988-07-13 Sandoz Ltd Improvements in/relating to organic compounds
FI93954C (fi) 1988-11-29 1995-06-26 Warner Lambert Co Menetelmä lääkeaineina käyttökelpoisten 3,5-di-tert-butyyli-4-hydroksifenyylisubstituoitujen 1,2,4- ja 1,3,4-tiadiatsolien sekä oksadiatsolien ja triatsolien valmistamiseksi
US5025032A (en) * 1989-10-17 1991-06-18 Oklahoma Medical Research Foundation Phenyl butyl nitrone compositions and methods for treatment of oxidative tissue damage
US5622994A (en) 1989-10-17 1997-04-22 Oklahoma Medical Research Foundation Spin trapping pharmaceutical compositions and methods for use thereof
US5036097A (en) 1989-10-17 1991-07-30 Oklahoma Medical Research Foundation Phenylbutyl nitrone compositions and methods for prevention of gastric ulceration
DK0496796T3 (da) 1989-10-17 1994-10-03 Oklahoma Med Res Found Fremgangsmåde og præparater til inhibering af sygdomme i forbindelse med oxidativ beskadigelse
US5143928A (en) 1990-03-27 1992-09-01 Warner-Lambert Company 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents
US6002001A (en) 1991-06-18 1999-12-14 Oklahoma Medical Research Foundation Spin trapping pharmaceutical compositions and methods for use thereof
US5270319A (en) 1991-09-09 1993-12-14 Warner-Lambert Company 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinflammatory agents
US5215986A (en) 1992-06-01 1993-06-01 Warner-Lambert Company 5-hydroxy-2-pyrimidinylmethylene oxaza heterocycles
US5840746A (en) 1993-06-24 1998-11-24 Merck Frosst Canada, Inc. Use of inhibitors of cyclooxygenase in the treatment of neurodegenerative diseases
US5455272A (en) * 1993-10-22 1995-10-03 Oklahoma Medical Research Foundation Spin trap nitronyl hindered phenols
US5488145A (en) 1993-12-23 1996-01-30 Oklahoma Medical Research Foundation 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps
TW450952B (en) 1996-04-23 2001-08-21 Centaur Pharmaceuticals Inc Ophthalmic pharmaceutical compositions comprising a nitrone compound
CA2260825A1 (en) 1996-07-19 1998-01-29 Centaur Pharmaceuticals, Inc. Furan nitrone compounds
TW429241B (en) * 1996-09-26 2001-04-11 Sumitomo Pharma Nitrone derivatives
US5994396A (en) 1997-08-18 1999-11-30 Centaur Pharmaceuticals, Inc. Furansulfonic acid derivatives and pharmaceutical compositions containing the same
US6046232A (en) 1997-10-17 2000-04-04 Centaur Pharmaceuticals, Inc. α-aryl-N-alkylnitrones and pharmaceutical compositions containing the same
US6015831A (en) 1998-01-16 2000-01-18 Centaur Pharmaceuticals, Inc. Thiophene nitrone compounds
WO1999036415A1 (en) 1998-01-16 1999-07-22 Centaur Pharmaceuticals, Inc. Thioether furan nitrone compounds
US6255353B1 (en) 1998-03-13 2001-07-03 Centaur Pharmaceuticals, Inc. Inhibition of angiogenesis
PT1077694E (pt) 1998-05-19 2004-12-31 Renovis Inc Produtos terapeuticos de arilnitrona para o tratamento da doenca inflamatoria dointestino

Also Published As

Publication number Publication date
UA66401C2 (en) 2004-05-17
HUP0104576A2 (hu) 2002-05-29
EA004931B1 (ru) 2004-10-28
NO20012727L (no) 2001-07-26
PL349916A1 (en) 2002-10-07
WO2000032567A1 (en) 2000-06-08
CA2353402A1 (en) 2000-06-08
KR20010087407A (ko) 2001-09-15
US6342523B1 (en) 2002-01-29
HK1044147A1 (zh) 2002-10-11
EP1135367A1 (en) 2001-09-26
AU773343B2 (en) 2004-05-20
NZ512032A (en) 2004-02-27
CN1334800A (zh) 2002-02-06
IS5958A (is) 2001-05-31
JP2002531435A (ja) 2002-09-24
CZ20011830A3 (cs) 2001-10-17
IL143506A0 (en) 2002-04-21
AU1929800A (en) 2000-06-19
HUP0104576A3 (en) 2002-11-28
ZA200104378B (en) 2002-08-28
SK7502001A3 (en) 2002-02-05
BR9915886A (pt) 2001-08-21
EA200100607A1 (ru) 2001-12-24

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application