BR9914221B1 - Derivados de glicopeptídeos e composições farmacêuticas contendo os mesmos - Google Patents
Derivados de glicopeptídeos e composições farmacêuticas contendo os mesmosInfo
- Publication number
- BR9914221B1 BR9914221B1 BRPI9914221-0B1A BR9914221A BR9914221B1 BR 9914221 B1 BR9914221 B1 BR 9914221B1 BR 9914221 A BR9914221 A BR 9914221A BR 9914221 B1 BR9914221 B1 BR 9914221B1
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- same
- derivatives
- glycopeptide derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11372898P | 1998-12-23 | 1998-12-23 | |
US12931399P | 1999-04-14 | 1999-04-14 | |
US16402499P | 1999-11-04 | 1999-11-04 | |
US16997899P | 1999-12-10 | 1999-12-10 | |
PCT/US1999/030543 WO2000039156A1 (en) | 1998-12-23 | 1999-12-22 | Glycopeptide derivatives and pharmaceutical compositions containing the same |
Publications (3)
Publication Number | Publication Date |
---|---|
BR9914221A BR9914221A (pt) | 2001-06-26 |
BR9914221B1 true BR9914221B1 (pt) | 2013-12-31 |
BRPI9914221B8 BRPI9914221B8 (pt) | 2021-05-25 |
Family
ID=27493926
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI9914221A BRPI9914221B8 (pt) | 1998-12-23 | 1999-12-22 | derivados de glicopeptídeos e composições farmacêuticas contendo os mesmos |
Country Status (23)
Country | Link |
---|---|
US (9) | US6392012B1 (pt) |
EP (1) | EP1140993B1 (pt) |
JP (1) | JP4362017B2 (pt) |
KR (1) | KR100665204B1 (pt) |
CN (1) | CN1249081C (pt) |
AT (1) | ATE242783T1 (pt) |
AU (1) | AU768204B2 (pt) |
BR (1) | BRPI9914221B8 (pt) |
CA (1) | CA2336445C (pt) |
CZ (1) | CZ301184B6 (pt) |
DE (1) | DE69908819T2 (pt) |
DK (1) | DK1140993T3 (pt) |
ES (1) | ES2201825T3 (pt) |
HK (1) | HK1040721B (pt) |
HU (1) | HU230190B1 (pt) |
IL (2) | IL140093A0 (pt) |
NO (1) | NO326066B1 (pt) |
NZ (1) | NZ508594A (pt) |
PL (1) | PL198311B1 (pt) |
PT (1) | PT1140993E (pt) |
SI (1) | SI1140993T1 (pt) |
WO (1) | WO2000039156A1 (pt) |
ZA (1) | ZA200007222B (pt) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU230190B1 (hu) * | 1998-12-23 | 2015-09-28 | Theravance, Inc | Glikopeptidszármazékok és ezeket tartalmazó gyógyászati kompozíciók |
AU4054900A (en) * | 1999-04-02 | 2000-10-23 | Advanced Medicine East, Inc. | Desleucyl glycopeptide antibiotics and methods of making same |
US6699836B2 (en) | 1999-04-02 | 2004-03-02 | The Trustees Of Princeton University | Vancomycin analogs |
AU2001238020A1 (en) * | 2000-02-04 | 2001-08-14 | Advanced Medicine, Inc. | Glycopeptide derivatives having antibiotic activity |
SI1278549T1 (sl) * | 2000-05-02 | 2009-04-30 | Theravance Inc | Sestavek, ki vsebuje ciklodekstrin in glikopeptidni antibiotik |
DE60135102D1 (de) | 2000-05-02 | 2008-09-11 | Theravance Inc | Verfahren zur reduktiven alkylierung von glykopeptiden |
AU2001259298A1 (en) * | 2000-05-02 | 2001-11-12 | Advanced Medicine, Inc. | Polyacid glycopeptide derivatives |
US6872804B2 (en) | 2000-06-22 | 2005-03-29 | Theravance, Inc. | Glycopeptide disulfide and thioester derivatives |
WO2001098329A1 (en) * | 2000-06-22 | 2001-12-27 | Theravance, Inc. | Polyhydroxy glycopeptide derivatives |
UA75083C2 (uk) | 2000-06-22 | 2006-03-15 | Тераванс, Інк. | Похідні глікопептидфосфонатів |
WO2001098327A2 (en) * | 2000-06-22 | 2001-12-27 | Theravance, Inc. | Glycopeptide carboxy-saccharide derivatives |
US6905669B2 (en) * | 2001-04-24 | 2005-06-14 | Supergen, Inc. | Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase |
TWI275594B (en) * | 2001-08-24 | 2007-03-11 | Theravance Inc | Process for preparing vancomycin phosphonate derivatives |
TWI312785B (en) * | 2001-08-24 | 2009-08-01 | Theravance Inc | Process for preparing vancomycin derivatives |
DE60118737T2 (de) | 2001-09-19 | 2006-10-19 | The Procter & Gamble Company, Cincinnati | Farbbedruckte Mehrschichtstruktur, ein damit hergestellter absorbierender Artikel und Verfahren zu deren Herstellung |
TWI335332B (en) | 2001-10-12 | 2011-01-01 | Theravance Inc | Cross-linked vancomycin-cephalosporin antibiotics |
CN101404986B (zh) | 2002-05-17 | 2011-09-28 | 赛奎拉公司 | 用于诊断和治疗感染性疾病的组合物和制药方法 |
US20040033986A1 (en) | 2002-05-17 | 2004-02-19 | Protopopova Marina Nikolaevna | Anti tubercular drug: compositions and methods |
WO2003099858A1 (en) | 2002-05-24 | 2003-12-04 | Theravance, Inc. | Cross-linked glycopeptide-cephalosporin antibiotics |
US6951963B2 (en) | 2002-06-17 | 2005-10-04 | Theravance, Inc. | Process for preparing N-protected β-amino aldehyde compounds |
BRPI0312654A2 (pt) * | 2002-07-09 | 2017-05-02 | Fasgen Llc | métodos de tratar infecções microbianas em seres humanos e animais |
HUE041133T2 (hu) * | 2002-11-18 | 2019-05-28 | Vicuron Pharmaceuticals Llc | Dalbavancin adagolási módszer bakteriális fertõzések kezelésére |
US20060074014A1 (en) * | 2002-11-18 | 2006-04-06 | Vicuron Pharmaceuticals Inc. | Dalbavancin compositions for treatment of bacterial infections |
WO2004113350A1 (en) | 2003-05-23 | 2004-12-29 | Theravance, Inc. | Cross-linked glycopeptide - cephalosporin antibiotics |
JP4555823B2 (ja) | 2003-07-11 | 2010-10-06 | セラヴァンス, インコーポレーテッド | 架橋されたグリコペプチド−セファロスポリン抗生物質 |
DE102004055582A1 (de) | 2004-11-18 | 2006-05-24 | Bayer Cropscience Ag | N-Heterocyclyl-phthalsäurediamide |
TW200626616A (en) | 2004-11-29 | 2006-08-01 | Univ Nagoya Nat Univ Corp | Monomer derivatives of glycopeptide antibiotics |
US8304597B2 (en) | 2004-12-15 | 2012-11-06 | The Procter And Gamble Company | Method of using an absorbent article having a functional enhancement indicator |
US20070185015A1 (en) * | 2005-02-28 | 2007-08-09 | Chiron Corporation and North China Pharmaceutical Corporation | Semi-synthetic desmethyl-vancomycin-based glycopeptides with antibiotic activity |
US7632918B2 (en) * | 2005-02-28 | 2009-12-15 | Novartis Vaccines And Diagnostics, Inc. | Semi-synthetic glycopeptides with antibiotic activity |
US7368422B2 (en) * | 2005-02-28 | 2008-05-06 | Novartis Vaccines And Diagnostics Inc. | Semi-synthetic rearranged vancomycin/desmethyl-vancomycin-based glycopeptides with antibiotic activity |
US8652504B2 (en) | 2005-09-22 | 2014-02-18 | Medivas, Llc | Solid polymer delivery compositions and methods for use thereof |
CA2623198C (en) | 2005-09-22 | 2014-08-05 | Medivas, Llc | Bis-(a-amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use |
US20070173438A1 (en) * | 2006-01-13 | 2007-07-26 | The Scripps Research Institute | [PSI[CH2NH]PG4] glycopeptide antibiotic analogs |
TW200808818A (en) * | 2006-05-26 | 2008-02-16 | Shionogi & Co | Glycopeptide antibiotic derivatives |
KR20100109936A (ko) * | 2007-12-26 | 2010-10-11 | 리드 테라퓨틱스, 인크. | 항박테리아제로서의 신규한 반(半)-합성 글리코펩티드 |
CN101959900A (zh) | 2007-12-26 | 2011-01-26 | 盐野义制药株式会社 | 糖肽类抗生素糖基化衍生物 |
EP2260060A4 (en) | 2008-04-01 | 2013-01-16 | Univ Cornell | ORGANIC SOLUBLE CHITOSA SALT AND CHITOSAN DERIVED BIOMATERIALS MANUFACTURED THEREFROM |
GB2465863A (en) * | 2008-12-05 | 2010-06-09 | Lead Therapeutics Inc | Semi-synthetic heptapeptidic glycopeptides for the treatment of bacterial infections |
CN101928330B (zh) * | 2009-06-26 | 2013-10-16 | 上海来益生物药物研究开发中心有限责任公司 | 一种新的化合物及其应用 |
EP2688580A4 (en) * | 2011-03-24 | 2015-03-25 | Seachaid Pharmaceuticals Inc | DERIVATIVES OF VANCOMYCIN |
TWI641372B (zh) | 2013-03-15 | 2018-11-21 | 美商梅琳塔有限責任公司 | 使用抗生素治療超重和肥胖患者感染的方法 |
US20160303184A1 (en) * | 2013-09-23 | 2016-10-20 | Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) | Vancomycin-sugar conjugates and uses thereof |
WO2016103284A1 (en) * | 2014-12-25 | 2016-06-30 | Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) | Glycopeptides and uses thereof |
CN109072271A (zh) * | 2016-01-15 | 2018-12-21 | 汉堡大学 | 用于制备鼠李糖基化类黄酮的方法 |
CN108698974A (zh) * | 2016-01-28 | 2018-10-23 | 阿卡特肖勒公司 | 光裂解底漆组合物和使用方法 |
CN107325159A (zh) * | 2016-04-29 | 2017-11-07 | 中国科学院上海药物研究所 | 一类万古霉素衍生物、其制备方法、药物组合物和用途 |
CA3062570A1 (en) | 2017-05-22 | 2018-11-29 | Insmed Incorporated | Lipo-glycopeptide cleavable derivatives and uses thereof |
CN107987131B (zh) * | 2017-11-16 | 2021-03-09 | 上海来益生物药物研究开发中心有限责任公司 | 一组具有抗耐药性细菌活性的化合物、其制备方法和应用 |
CN108409837B (zh) | 2018-03-06 | 2021-09-24 | 上海来益生物药物研究开发中心有限责任公司 | 一组具有抗耐药性细菌活性的糖肽类化合物、其制备方法和应用 |
NL2023883B1 (en) * | 2019-09-24 | 2021-04-26 | Univ Leiden | Antibiotic compounds |
CN111620931B (zh) * | 2020-06-12 | 2021-12-17 | 苏州博源医疗科技有限公司 | 万古霉素衍生物及其制备方法和应用 |
CN114213284B (zh) * | 2022-01-04 | 2023-08-01 | 丽珠集团福州福兴医药有限公司 | (9h-芴-9-基)-癸基(2-氧代乙基)氨基甲酸甲酯及其合成方法 |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4497802A (en) | 1983-10-21 | 1985-02-05 | Eli Lilly And Company | N-Acyl glycopeptide derivatives |
US4914187A (en) | 1984-11-13 | 1990-04-03 | Gruppo Lepetit S.P.A | Ester derivatives of antibiotic L 17046 |
GB8428619D0 (en) | 1984-11-13 | 1984-12-19 | Lepetit Spa | Derivatives of antibiotic l 17046 |
US4698327A (en) | 1985-04-25 | 1987-10-06 | Eli Lilly And Company | Novel glycopeptide derivatives |
US4639433A (en) | 1985-08-14 | 1987-01-27 | Eli Lilly And Company | Glycopeptide derivatives |
US4643987A (en) | 1985-08-14 | 1987-02-17 | Eli Lilly And Company | Modified glycopeptides |
GB8704847D0 (en) | 1987-03-02 | 1987-04-08 | Lepetit Spa | Substituted alkylamides of teicoplanin compounds |
FR2632185B1 (fr) * | 1988-06-01 | 1992-05-22 | Rhone Poulenc Chimie | Silice pour compositions dentifrices compatible notamment avec le zinc |
GB8817397D0 (en) | 1988-07-21 | 1988-08-24 | Lepetit Spa | N15-alkyl & n15 n15-di-alkyl derivatives of teicoplanin antibiotics carrying functional groups on alkyl side chain |
US5534420A (en) | 1988-07-28 | 1996-07-09 | Eli Lilly And Company | Biotransformation of glycopeptide antibiotics |
EP0376041B1 (en) | 1988-12-27 | 1996-02-28 | GRUPPO LEPETIT S.p.A. | C63-Amide derivatives of 34-de(acetylglucosaminyl)-34-deoxy-teicoplanins |
IE64155B1 (en) | 1989-03-29 | 1995-07-12 | Lepetit Spa | New substituted alkylamide derivatives of teicoplanin |
NZ236393A (en) | 1989-12-13 | 1992-05-26 | Lilly Co Eli | N-alkylated glycopeptide derivatives prepared from antibiotics a82846 series and pa-42867-a; pharmaceutical compositions |
AU647122B2 (en) | 1990-05-28 | 1994-03-17 | Gruppo Lepetit S.P.A. | C63-amide derivatives of 34-de(acetylglucosaminyl)-34-deoxy- teicoplanin and their use as medicaments against bacteria resistant to glycopeptide antibiotics |
WO1992017456A1 (en) | 1991-03-26 | 1992-10-15 | Fujisawa Pharmaceutical Co., Ltd. | Amino acid derivative and salt thereof |
US5750509A (en) | 1991-07-29 | 1998-05-12 | Gruppo Lepetit S.P.A. | Amide derivatives of antibiotic A 40926 |
UA41283C2 (uk) | 1991-07-29 | 2001-09-17 | Біосерч Італіа С.П.А. | Похідні антибіотику а 40926 та способи їх одержання |
RU2145609C1 (ru) | 1994-01-28 | 2000-02-20 | Эли Лилли Энд Компани | Производные гликопептида или их соли, способ получения, фармацевтическая композиция |
US5840684A (en) | 1994-01-28 | 1998-11-24 | Eli Lilly And Company | Glycopeptide antibiotic derivatives |
IT1282586B1 (it) | 1996-02-08 | 1998-03-31 | Chemical And Biolog Ind | Composizioni farmaceutiche per il trattamento biologico delle infezioni dovute a ceppi di enterococcus faecium resistenti agli |
EP0934076A1 (en) | 1996-03-21 | 1999-08-11 | Intercardia, Inc. | Solid phase lipoglycopeptide library, compositions and methods |
CA2251086C (en) | 1996-04-12 | 2007-02-20 | Eli Lilly And Company | Glycopeptide compounds |
WO1997038702A1 (en) | 1996-04-12 | 1997-10-23 | Eli Lilly And Company | Covalently-linked glycopeptide dimers |
EP0912604B1 (en) | 1996-04-23 | 2001-11-14 | Biosearch Italia S.p.A. | Improved chemical process for preparing amide derivatives of antibiotic A 40926 |
US5919756A (en) | 1996-06-28 | 1999-07-06 | Eli Lilly And Company | Amides |
US5939382A (en) | 1996-11-21 | 1999-08-17 | Eli Lilly And Company | Reducing agent for reductive alkylation of glycopeptide antibiotics |
US5952466A (en) | 1997-11-12 | 1999-09-14 | Eli Lilly And Company | Reductive alkylation of glycopeptide antibiotics |
US5916873A (en) | 1997-04-17 | 1999-06-29 | Eli Lilly And Company | Teicoplanin derivatives |
US5977063A (en) | 1997-05-20 | 1999-11-02 | Eli Lilly And Company | Alkylated hexapeptides |
US5952310A (en) | 1997-05-20 | 1999-09-14 | Eli Lilly And Company | Glycopeptide hexapeptides |
US5919771A (en) | 1997-05-20 | 1999-07-06 | Eli Lilly And Company | Urea and thiourea derivatives of glycopeptides |
AU3307399A (en) | 1998-02-20 | 1999-09-06 | Advanced Medicine, Inc. | Novel antibacterial agents |
US6518242B1 (en) | 1998-02-20 | 2003-02-11 | Theravance, Inc. | Derivatives of glycopeptide antibacterial agents |
ES2283107T3 (es) | 1998-05-01 | 2007-10-16 | Eli Lilly And Company | Glicopeptidos modificados en n1. |
NZ509165A (en) | 1998-07-14 | 2003-08-29 | Univ Princeton | Glycopeptide antobiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same |
HU230190B1 (hu) * | 1998-12-23 | 2015-09-28 | Theravance, Inc | Glikopeptidszármazékok és ezeket tartalmazó gyógyászati kompozíciók |
UA75083C2 (uk) | 2000-06-22 | 2006-03-15 | Тераванс, Інк. | Похідні глікопептидфосфонатів |
WO2003099858A1 (en) | 2002-05-24 | 2003-12-04 | Theravance, Inc. | Cross-linked glycopeptide-cephalosporin antibiotics |
JP4555823B2 (ja) | 2003-07-11 | 2010-10-06 | セラヴァンス, インコーポレーテッド | 架橋されたグリコペプチド−セファロスポリン抗生物質 |
-
1999
- 1999-12-22 HU HU0400887A patent/HU230190B1/hu unknown
- 1999-12-22 DE DE69908819T patent/DE69908819T2/de not_active Expired - Lifetime
- 1999-12-22 CN CNB99809434XA patent/CN1249081C/zh not_active Expired - Lifetime
- 1999-12-22 EP EP99965331A patent/EP1140993B1/en not_active Expired - Lifetime
- 1999-12-22 AU AU31273/00A patent/AU768204B2/en not_active Expired
- 1999-12-22 PL PL348451A patent/PL198311B1/pl unknown
- 1999-12-22 AT AT99965331T patent/ATE242783T1/de active
- 1999-12-22 ES ES99965331T patent/ES2201825T3/es not_active Expired - Lifetime
- 1999-12-22 JP JP2000591067A patent/JP4362017B2/ja not_active Expired - Fee Related
- 1999-12-22 US US09/470,209 patent/US6392012B1/en not_active Expired - Lifetime
- 1999-12-22 IL IL14009399A patent/IL140093A0/xx active IP Right Grant
- 1999-12-22 BR BRPI9914221A patent/BRPI9914221B8/pt not_active IP Right Cessation
- 1999-12-22 CA CA2336445A patent/CA2336445C/en not_active Expired - Lifetime
- 1999-12-22 DK DK99965331T patent/DK1140993T3/da active
- 1999-12-22 CZ CZ20010022A patent/CZ301184B6/cs not_active IP Right Cessation
- 1999-12-22 KR KR1020017003918A patent/KR100665204B1/ko active IP Right Grant
- 1999-12-22 SI SI9930389T patent/SI1140993T1/xx unknown
- 1999-12-22 NZ NZ508594A patent/NZ508594A/en not_active IP Right Cessation
- 1999-12-22 WO PCT/US1999/030543 patent/WO2000039156A1/en active IP Right Grant
- 1999-12-22 PT PT99965331T patent/PT1140993E/pt unknown
-
2000
- 2000-09-06 US US09/656,473 patent/US6444786B1/en not_active Expired - Lifetime
- 2000-11-01 US US09/674,456 patent/US6455669B1/en not_active Expired - Lifetime
- 2000-12-05 IL IL140093A patent/IL140093A/en not_active IP Right Cessation
- 2000-12-06 ZA ZA200007222A patent/ZA200007222B/xx unknown
- 2000-12-12 NO NO20006323A patent/NO326066B1/no not_active IP Right Cessation
-
2002
- 2002-03-06 US US10/092,088 patent/US6962970B2/en not_active Expired - Lifetime
- 2002-03-21 HK HK02102171.5A patent/HK1040721B/zh unknown
-
2004
- 2004-04-15 US US10/825,038 patent/US6949681B2/en not_active Expired - Lifetime
-
2005
- 2005-05-13 US US11/128,901 patent/US7101964B2/en not_active Expired - Lifetime
-
2006
- 2006-04-17 US US11/405,234 patent/US7351791B2/en not_active Expired - Fee Related
-
2007
- 2007-10-24 US US11/977,377 patent/US7723470B2/en not_active Expired - Fee Related
-
2009
- 2009-05-08 US US12/437,778 patent/US8030445B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT1140993E (pt) | Derivados de glicopeptidos e composicoes farmaceuticas contendo os mesmos | |
EA200300050A1 (ru) | Гликопептидфосфонатные производные | |
TR200101126T2 (tr) | İkameli fenil türevleri, hazırlanma ve kullanımları | |
EA199900373A2 (ru) | Фармацевтические композиции | |
BR9804815A (pt) | "composições antimicrobianas" | |
BR9908004A (pt) | Composto, composição e método para prevençãoou supressão de uma infecção viral | |
DE60204452D1 (de) | Pyrazolo[1,5]pyridinderivate | |
BR0112030A (pt) | Novos compostos que possuem atividade antibacteriana, antifúngica ou antitumor | |
TR200200579T2 (tr) | Amino-tirazolpiridin türevleri. | |
ES2243579T3 (es) | Derivados de pirazolopirideno. | |
SE9804212D0 (sv) | Compounds | |
SE9801494D0 (sv) | Novel use | |
TR200002932T2 (tr) | Azabisayklik 5HT1 Alıcı liganolları | |
BR9902084A (pt) | Heterociclos. | |
DE69936052D1 (de) | N1 modifizierte glycopeptide | |
SE9904128D0 (sv) | Novel compounds | |
AU2002357740A1 (en) | Pyrazolo-pyridine derivatives as antiherpes agents | |
PT1104419E (pt) | Derivados de azabicicloheptano substituidos no azoto sua preparacao e utilizacao | |
MY123217A (en) | Glycopeptide derivatives and pharmaceutical compositions containing the same | |
PT1140932E (pt) | Derivados de 1,8-benzonaftiridina | |
TR200103169T2 (tr) | 1,5-Benzodiazepin türevleri | |
BR9915898A (pt) | Compostos, composição farmacêutica, e, utilização de um composto | |
RS50412B (sr) | Derivati tiazofurina | |
TH57990B (th) | อนุพันธ์ของไกลโคเพปไทด์และองค์ประกอบทางเภสัชกรรมซึ่งมีสารชนิดเดียวกัน | |
ECSP993299A (es) | Derivados glicopeptidicos y composiciones farmaceuticas que los contienen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 31/12/2013, OBSERVADAS AS CONDICOES LEGAIS. |
|
B25A | Requested transfer of rights approved | ||
B25A | Requested transfer of rights approved | ||
B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 22/12/1999 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |
|
B21A | Patent or certificate of addition expired [chapter 21.1 patent gazette] |
Free format text: PATENTE EXTINTA EM 22/12/2019 |