UA48958C2 - 9-o-оксимові похідні еритроміцину а та фармацевтична композиція на їх основі - Google Patents

9-o-оксимові похідні еритроміцину а та фармацевтична композиція на їх основі

Info

Publication number
UA48958C2
UA48958C2 UA97073719A UA97073719A UA48958C2 UA 48958 C2 UA48958 C2 UA 48958C2 UA 97073719 A UA97073719 A UA 97073719A UA 97073719 A UA97073719 A UA 97073719A UA 48958 C2 UA48958 C2 UA 48958C2
Authority
UA
Ukraine
Prior art keywords
erythromycine
pharmaceutical composition
oxime derivatives
compounds
formula
Prior art date
Application number
UA97073719A
Other languages
English (en)
Russian (ru)
Inventor
Франко Пеллачіні
Джованна Скоппакассі
Енріко Альбіні
Даніела Ботта
Стефано Романьяно
Франческо Сантанжело
Original Assignee
Цамбон Груп С. П. А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Цамбон Груп С. П. А. filed Critical Цамбон Груп С. П. А.
Publication of UA48958C2 publication Critical patent/UA48958C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

У заявці описані сполуки формули (І) , (I) де A, R1, R2, М, n, m і r мають значення, вказані в описі, способи їх одержання та фармацевтичні композиції, що містять їх як діючі речовини. Сполуки формули (І) придатні для лікування інфекційних захворювань.
UA97073719A 1994-12-13 1995-12-07 9-o-оксимові похідні еритроміцину а та фармацевтична композиція на їх основі UA48958C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT94MI002496A IT1276901B1 (it) 1994-12-13 1994-12-13 Derivati dell'eritromicina a 9-0-ossina dotati di attivita' antibiotica
PCT/EP1995/004815 WO1996018633A1 (en) 1994-12-13 1995-12-07 Erythromycin a 9-0-oxime derivatives endowed with antibiotic activity

Publications (1)

Publication Number Publication Date
UA48958C2 true UA48958C2 (uk) 2002-09-16

Family

ID=11369979

Family Applications (1)

Application Number Title Priority Date Filing Date
UA97073719A UA48958C2 (uk) 1994-12-13 1995-12-07 9-o-оксимові похідні еритроміцину а та фармацевтична композиція на їх основі

Country Status (35)

Country Link
US (1) US5847092A (uk)
EP (1) EP0797579B1 (uk)
JP (1) JPH10510520A (uk)
KR (1) KR100367559B1 (uk)
CN (1) CN1046535C (uk)
AP (1) AP739A (uk)
AT (1) ATE190620T1 (uk)
AU (1) AU690791B2 (uk)
BG (1) BG63261B1 (uk)
BR (1) BR9510015A (uk)
CA (1) CA2207029A1 (uk)
CZ (1) CZ289943B6 (uk)
DE (1) DE69515694T2 (uk)
DK (1) DK0797579T3 (uk)
EE (1) EE03401B1 (uk)
ES (1) ES2144154T3 (uk)
FI (1) FI972493A0 (uk)
GE (1) GEP20012391B (uk)
GR (1) GR3033622T3 (uk)
HU (1) HU220631B1 (uk)
IT (1) IT1276901B1 (uk)
LT (1) LT4276B (uk)
LV (1) LV11898B (uk)
MD (1) MD1788G2 (uk)
NO (1) NO309816B1 (uk)
NZ (1) NZ297446A (uk)
OA (1) OA10491A (uk)
PL (1) PL182053B1 (uk)
PT (1) PT797579E (uk)
RO (1) RO116282B1 (uk)
RU (1) RU2152951C1 (uk)
SI (1) SI9520124A (uk)
TJ (1) TJ306B (uk)
UA (1) UA48958C2 (uk)
WO (1) WO1996018633A1 (uk)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1290447B1 (it) 1997-03-28 1998-12-03 Zambon Spa Derivati 1,3-ossatiolanici ad attivita' antivirale
IT1301968B1 (it) * 1998-07-30 2000-07-20 Zambon Spa Derivati di eritromicina ad attivita' antibiotica
IT1301967B1 (it) * 1998-07-30 2000-07-20 Zambon Spa Derivato di eritromicina ad attivita' antibiotica
IT1306205B1 (it) * 1999-01-15 2001-05-30 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
US6638908B1 (en) 2000-08-09 2003-10-28 Yale University Crystals of the large ribosomal subunit
US6947844B2 (en) 2000-08-09 2005-09-20 Yale University Modulators of ribosomal function and identification thereof
US6952650B2 (en) 2001-08-03 2005-10-04 Yale University Modulators of ribosomal function and identification thereof
IL151012A0 (en) 2001-08-03 2003-02-12 Ribosomes Structure And Protei Ribosomes structure and protein synthesis inhibitors
ITMI20021726A1 (it) 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
US7091196B2 (en) 2002-09-26 2006-08-15 Rib-X Pharmaceuticals, Inc. Bifunctional heterocyclic compounds and methods of making and using same
EP1723159B1 (en) 2004-02-27 2019-06-12 Melinta Therapeutics, Inc. Macrocyclic compounds and methods of making and using the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2473525A1 (fr) * 1980-01-11 1981-07-17 Roussel Uclaf Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments
GB8521402D0 (en) 1985-08-28 1985-10-02 Beecham Group Plc Chemical compounds
US4740502A (en) * 1986-06-20 1988-04-26 Abbott Laboratories Semisynthetic erythromycin antibiotics
PT86800B (pt) 1987-02-24 1992-05-29 Beecham Group Plc Processo para a preparacao de derivados de eritromicina
US5302705A (en) * 1989-10-07 1994-04-12 Taisho Pharmaceutical Co., Ltd. 6-O-methylerythromycin a oxime derivatives
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin

Also Published As

Publication number Publication date
OA10491A (en) 2002-04-10
DK0797579T3 (da) 2000-06-05
DE69515694T2 (de) 2000-10-26
ATE190620T1 (de) 2000-04-15
SI9520124A (sl) 1998-04-30
FI972493A (fi) 1997-06-12
MD1788F2 (en) 2001-11-30
MD1788G2 (ro) 2002-05-31
IT1276901B1 (it) 1997-11-03
EE03401B1 (et) 2001-04-16
HU220631B1 (hu) 2002-03-28
AU4260396A (en) 1996-07-03
NO309816B1 (no) 2001-04-02
RO116282B1 (ro) 2000-12-29
JPH10510520A (ja) 1998-10-13
DE69515694D1 (de) 2000-04-20
CN1169727A (zh) 1998-01-07
GEP20012391B (en) 2001-03-25
CZ178697A3 (en) 1997-12-17
PL320688A1 (en) 1997-10-27
NO972702D0 (no) 1997-06-12
GR3033622T3 (en) 2000-10-31
CN1046535C (zh) 1999-11-17
AP739A (en) 1999-03-24
LV11898B (en) 1998-03-20
US5847092A (en) 1998-12-08
ES2144154T3 (es) 2000-06-01
PL182053B1 (pl) 2001-10-31
LT97116A (en) 1997-10-27
RU2152951C1 (ru) 2000-07-20
PT797579E (pt) 2000-08-31
KR100367559B1 (ko) 2003-04-21
MD970243A (en) 1999-05-31
EP0797579B1 (en) 2000-03-15
WO1996018633A1 (en) 1996-06-20
HUT77126A (hu) 1998-03-02
AU690791B2 (en) 1998-04-30
EP0797579A1 (en) 1997-10-01
TJ306B (en) 2001-08-06
BG63261B1 (bg) 2001-07-31
CA2207029A1 (en) 1996-06-20
BG101570A (en) 1998-02-27
EE9700124A (et) 1997-12-15
LV11898A (lv) 1997-12-20
AP9700989A0 (en) 1997-07-31
BR9510015A (pt) 1997-10-28
CZ289943B6 (cs) 2002-04-17
NZ297446A (en) 1999-06-29
FI972493A0 (fi) 1997-06-12
ITMI942496A0 (it) 1994-12-13
NO972702L (no) 1997-08-13
MX9704253A (es) 1997-09-30
LT4276B (lt) 1998-01-26
ITMI942496A1 (it) 1996-06-13

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