KR100512506B1 - 제약제제로서신규한치환시클릭아미노산 - Google Patents

제약제제로서신규한치환시클릭아미노산 Download PDF

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Publication number
KR100512506B1
KR100512506B1 KR10-1998-0707229A KR19980707229A KR100512506B1 KR 100512506 B1 KR100512506 B1 KR 100512506B1 KR 19980707229 A KR19980707229 A KR 19980707229A KR 100512506 B1 KR100512506 B1 KR 100512506B1
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South Korea
Prior art keywords
mmol
mixture
give
solid
solution
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Expired - Fee Related
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KR10-1998-0707229A
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English (en)
Korean (ko)
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KR19990087756A (ko
Inventor
데이빗 크리스토퍼 호웰
져스틴 에스. 브라이언스
클레어 오. 닌
앤드류 아이 모렐
길스 에스 렛트클리프
요한네스 하르텐스타인
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워너-램버트 캄파니 엘엘씨
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Publication of KR19990087756A publication Critical patent/KR19990087756A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A61P25/12—Antiepileptics; Anticonvulsants for grand-mal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
KR10-1998-0707229A 1996-03-14 1997-02-18 제약제제로서신규한치환시클릭아미노산 Expired - Fee Related KR100512506B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1343296P 1996-03-14 1996-03-14
US60/013,432 1996-03-14

Publications (2)

Publication Number Publication Date
KR19990087756A KR19990087756A (ko) 1999-12-27
KR100512506B1 true KR100512506B1 (ko) 2005-12-21

Family

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Family Applications (1)

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KR10-1998-0707229A Expired - Fee Related KR100512506B1 (ko) 1996-03-14 1997-02-18 제약제제로서신규한치환시클릭아미노산

Country Status (29)

Country Link
US (1) US6103932A (https=)
EP (1) EP0888286B1 (https=)
JP (1) JP2000506861A (https=)
KR (1) KR100512506B1 (https=)
AT (1) ATE207878T1 (https=)
AU (1) AU734173B2 (https=)
BG (1) BG63662B1 (https=)
BR (1) BR9708200A (https=)
CA (1) CA2244912C (https=)
CZ (1) CZ293759B6 (https=)
DE (1) DE69707842T2 (https=)
DK (2) DK0888286T3 (https=)
EA (1) EA002765B1 (https=)
EE (1) EE9800309A (https=)
ES (1) ES2167717T3 (https=)
GE (1) GEP20012413B (https=)
HU (1) HU224720B1 (https=)
IL (1) IL125544A (https=)
IS (1) IS1990B (https=)
MX (1) MX9806069A (https=)
NO (1) NO984205L (https=)
NZ (1) NZ331143A (https=)
PL (1) PL185991B1 (https=)
PT (1) PT888286E (https=)
SK (1) SK283295B6 (https=)
TR (1) TR199801807T2 (https=)
UA (1) UA49011C2 (https=)
WO (1) WO1997033858A1 (https=)
ZA (1) ZA972200B (https=)

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IS1990B (is) 2005-02-15
IL125544A (en) 2002-03-10
SK283295B6 (sk) 2003-05-02
DE69707842T2 (de) 2002-05-16
CZ286398A3 (cs) 1999-03-17
GEP20012413B (en) 2001-04-25
SK123898A3 (en) 2000-04-10
HU224720B1 (en) 2006-01-30
IS4819A (is) 1998-08-10
ATE207878T1 (de) 2001-11-15
HUP9902136A3 (en) 2000-03-28
TR199801807T2 (xx) 1998-12-21
EP0888286A1 (en) 1999-01-07
AU2051197A (en) 1997-10-01
BG102733A (en) 1999-04-30
CZ293759B6 (cs) 2004-07-14
IL125544A0 (en) 1999-03-12
EA002765B1 (ru) 2002-08-29
JP2000506861A (ja) 2000-06-06
EE9800309A (et) 1999-02-15
BR9708200A (pt) 1999-07-27
HUP9902136A2 (hu) 1999-10-28
MX9806069A (es) 1998-11-30
DE69707842D1 (de) 2001-12-06
AU734173B2 (en) 2001-06-07
CA2244912C (en) 2005-07-12
NZ331143A (en) 2001-06-29
UA49011C2 (uk) 2002-09-16
WO1997033858A1 (en) 1997-09-18
KR19990087756A (ko) 1999-12-27
EP0888286B1 (en) 2001-10-31
EA199800798A1 (ru) 1999-04-29
ZA972200B (en) 1997-09-17
US6103932A (en) 2000-08-15
ES2167717T3 (es) 2002-05-16
NO984205D0 (no) 1998-09-11
DK0888285T3 (da) 2002-04-08
DK0888286T3 (da) 2002-02-18
CA2244912A1 (en) 1997-09-18
PL328816A1 (en) 1999-02-15
BG63662B1 (bg) 2002-08-30
PL185991B1 (pl) 2003-09-30
NO984205L (no) 1998-09-14
PT888286E (pt) 2002-04-29

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