ZA972200B - Novel bridged cyclic amino acids as pharmaceutical agents. - Google Patents

Novel bridged cyclic amino acids as pharmaceutical agents.

Info

Publication number
ZA972200B
ZA972200B ZA9702200A ZA972200A ZA972200B ZA 972200 B ZA972200 B ZA 972200B ZA 9702200 A ZA9702200 A ZA 9702200A ZA 972200 A ZA972200 A ZA 972200A ZA 972200 B ZA972200 B ZA 972200B
Authority
ZA
South Africa
Prior art keywords
amino acids
pct
cyclic amino
pharmaceutical agents
bridged cyclic
Prior art date
Application number
ZA9702200A
Other languages
English (en)
Inventor
David Christopher Horwell
Justin S Bryans
Clare O Kneen
Andrew I Morrell
Giles S Ratcliffe
Johannes Hartenstein
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of ZA972200B publication Critical patent/ZA972200B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A61P25/12—Antiepileptics; Anticonvulsants for grand-mal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
ZA9702200A 1996-03-14 1997-03-13 Novel bridged cyclic amino acids as pharmaceutical agents. ZA972200B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1343296P 1996-03-14 1996-03-14

Publications (1)

Publication Number Publication Date
ZA972200B true ZA972200B (en) 1997-09-17

Family

ID=21759938

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9702200A ZA972200B (en) 1996-03-14 1997-03-13 Novel bridged cyclic amino acids as pharmaceutical agents.

Country Status (29)

Country Link
US (1) US6103932A (xx)
EP (1) EP0888286B1 (xx)
JP (1) JP2000506861A (xx)
KR (1) KR100512506B1 (xx)
AT (1) ATE207878T1 (xx)
AU (1) AU734173B2 (xx)
BG (1) BG63662B1 (xx)
BR (1) BR9708200A (xx)
CA (1) CA2244912C (xx)
CZ (1) CZ293759B6 (xx)
DE (1) DE69707842T2 (xx)
DK (2) DK0888285T3 (xx)
EA (1) EA002765B1 (xx)
EE (1) EE9800309A (xx)
ES (1) ES2167717T3 (xx)
GE (1) GEP20012413B (xx)
HU (1) HU224720B1 (xx)
IL (1) IL125544A (xx)
IS (1) IS1990B (xx)
MX (1) MX9806069A (xx)
NO (1) NO984205L (xx)
NZ (1) NZ331143A (xx)
PL (1) PL185991B1 (xx)
PT (1) PT888286E (xx)
SK (1) SK283295B6 (xx)
TR (1) TR199801807T2 (xx)
UA (1) UA49011C2 (xx)
WO (1) WO1997033858A1 (xx)
ZA (1) ZA972200B (xx)

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Also Published As

Publication number Publication date
IS1990B (is) 2005-02-15
PL328816A1 (en) 1999-02-15
UA49011C2 (uk) 2002-09-16
DE69707842T2 (de) 2002-05-16
SK123898A3 (en) 2000-04-10
AU734173B2 (en) 2001-06-07
KR19990087756A (ko) 1999-12-27
NO984205D0 (no) 1998-09-11
EE9800309A (et) 1999-02-15
CA2244912A1 (en) 1997-09-18
KR100512506B1 (ko) 2005-12-21
CZ293759B6 (cs) 2004-07-14
CZ286398A3 (cs) 1999-03-17
US6103932A (en) 2000-08-15
EP0888286B1 (en) 2001-10-31
IL125544A (en) 2002-03-10
IS4819A (is) 1998-08-10
WO1997033858A1 (en) 1997-09-18
ATE207878T1 (de) 2001-11-15
JP2000506861A (ja) 2000-06-06
PL185991B1 (pl) 2003-09-30
IL125544A0 (en) 1999-03-12
EA199800798A1 (ru) 1999-04-29
GEP20012413B (en) 2001-04-25
NZ331143A (en) 2001-06-29
DE69707842D1 (de) 2001-12-06
DK0888286T3 (da) 2002-02-18
AU2051197A (en) 1997-10-01
HUP9902136A3 (en) 2000-03-28
TR199801807T2 (xx) 1998-12-21
HU224720B1 (en) 2006-01-30
BG63662B1 (bg) 2002-08-30
HUP9902136A2 (hu) 1999-10-28
EA002765B1 (ru) 2002-08-29
CA2244912C (en) 2005-07-12
EP0888286A1 (en) 1999-01-07
DK0888285T3 (da) 2002-04-08
PT888286E (pt) 2002-04-29
BR9708200A (pt) 1999-07-27
SK283295B6 (sk) 2003-05-02
MX9806069A (es) 1998-11-30
NO984205L (no) 1998-09-14
BG102733A (en) 1999-04-30
ES2167717T3 (es) 2002-05-16

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