|
US5824311A
(en)
|
1987-11-30 |
1998-10-20 |
Trustees Of The University Of Pennsylvania |
Treatment of tumors with monoclonal antibodies against oncogene antigens
|
|
US4870287A
(en)
|
1988-03-03 |
1989-09-26 |
Loma Linda University Medical Center |
Multi-station proton beam therapy system
|
|
US5851795A
(en)
|
1991-06-27 |
1998-12-22 |
Bristol-Myers Squibb Company |
Soluble CTLA4 molecules and uses thereof
|
|
US6416998B1
(en)
|
1992-09-02 |
2002-07-09 |
Baylor College Of Medicine |
Plasmid encoding a modified steroid hormone
|
|
US5846945A
(en)
|
1993-02-16 |
1998-12-08 |
Onyx Pharmaceuticals, Inc. |
Cytopathic viruses for therapy and prophylaxis of neoplasia
|
|
US5801005A
(en)
|
1993-03-17 |
1998-09-01 |
University Of Washington |
Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
|
|
WO1995001994A1
(en)
|
1993-07-09 |
1995-01-19 |
Synergen, Inc. |
Recombinant ctla4 polypeptides and methods for making the same
|
|
GB9506466D0
(en)
|
1994-08-26 |
1995-05-17 |
Prolifix Ltd |
Cell cycle regulated repressor and dna element
|
|
ES2201177T3
(es)
|
1995-03-08 |
2004-03-16 |
The Scripps Research Institute |
Sistema de presentacion de antigenos y activacion de celulas-t.
|
|
US5763270A
(en)
|
1995-06-07 |
1998-06-09 |
Genemedicine, Inc. |
Plasmid for delivery of nucleic acids to cells and methods of use
|
|
US6013516A
(en)
|
1995-10-06 |
2000-01-11 |
The Salk Institute For Biological Studies |
Vector and method of use for nucleic acid delivery to non-dividing cells
|
|
WO1997034634A1
(en)
|
1996-03-20 |
1997-09-25 |
Sloan-Kettering Institute For Cancer Research |
Single chain fv constructs of anti-ganglioside gd2 antibodies
|
|
US5760395A
(en)
|
1996-04-18 |
1998-06-02 |
Universities Research Assoc., Inc. |
Method and apparatus for laser-controlled proton beam radiology
|
|
CA2254975C
(en)
|
1996-05-23 |
2008-12-16 |
The Scripps Research Institute |
Mhc class ii antigen-presenting systems and methods for activating cd4+ t cells
|
|
US5739169A
(en)
|
1996-05-31 |
1998-04-14 |
Procept, Incorporated |
Aromatic compounds for inhibiting immune response
|
|
US5844905A
(en)
|
1996-07-09 |
1998-12-01 |
International Business Machines Corporation |
Extensions to distributed MAC protocols with collision avoidance using RTS/CTS exchange
|
|
WO1998042752A1
(en)
|
1997-03-21 |
1998-10-01 |
Brigham And Women's Hospital Inc. |
Immunotherapeutic ctla-4 binding peptides
|
|
US5994136A
(en)
|
1997-12-12 |
1999-11-30 |
Cell Genesys, Inc. |
Method and means for producing high titer, safe, recombinant lentivirus vectors
|
|
DE69942214D1
(de)
|
1998-02-05 |
2010-05-12 |
Glaxosmithkline Biolog Sa |
Verfahren zur Reinigung oder Herstellung der MAGE Protein
|
|
WO2000014257A1
(en)
|
1998-09-04 |
2000-03-16 |
Sloan-Kettering Institute For Cancer Research |
Fusion receptors specific for prostate-specific membrane antigen and uses thereof
|
|
AU2472400A
(en)
|
1998-10-20 |
2000-05-08 |
City Of Hope |
CD20-specific redirected T cells and their use in cellular immunotherapy of CD20+ malignancies
|
|
WO2000037504A2
(en)
|
1998-12-23 |
2000-06-29 |
Pfizer Inc. |
Human monoclonal antibodies to ctla-4
|
|
US6790662B1
(en)
|
1999-03-12 |
2004-09-14 |
Ortho-Mcneil Pharmaceutical, Inc. |
Method of isolating CD8+ cells, and related hybridoma cells antibodies and polypeptides
|
|
TR200103018T2
(tr)
|
1999-04-19 |
2002-02-21 |
Beecham Biologicals S.A. Smithkline |
İmmünostimülatör oligonükleotid ve saponin içeren katkı bileşikleri.
|
|
EP1212422B1
(en)
|
1999-08-24 |
2007-02-21 |
Medarex, Inc. |
Human ctla-4 antibodies and their uses
|
|
US7605238B2
(en)
|
1999-08-24 |
2009-10-20 |
Medarex, Inc. |
Human CTLA-4 antibodies and their uses
|
|
WO2001094944A2
(en)
|
2000-06-02 |
2001-12-13 |
Memorial Sloan-Kettering Cancer Center |
Artificial antigen presenting cells and methods of use thereof
|
|
EP1334188B1
(en)
|
2000-11-07 |
2006-08-30 |
City of Hope |
Cd19-specific redirected immune cells
|
|
US20040071671A1
(en)
|
2001-02-20 |
2004-04-15 |
Leturcq Didier J. |
Cell therapy method for the treatment of tumors
|
|
US7070995B2
(en)
|
2001-04-11 |
2006-07-04 |
City Of Hope |
CE7-specific redirected immune cells
|
|
US20090257994A1
(en)
|
2001-04-30 |
2009-10-15 |
City Of Hope |
Chimeric immunoreceptor useful in treating human cancers
|
|
US20030211603A1
(en)
|
2001-08-14 |
2003-11-13 |
Earp David J. |
Reprogramming cells for enhanced differentiation capacity using pluripotent stem cells
|
|
US7446190B2
(en)
|
2002-05-28 |
2008-11-04 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acids encoding chimeric T cell receptors
|
|
AU2003263653A1
(en)
|
2002-09-27 |
2004-04-19 |
Daewoong Co., Ltd. |
A vaccine enhancing the protective immunity to hepatitis c virus using plasmid dna and recombinant adenovirus
|
|
US20060104968A1
(en)
|
2003-03-05 |
2006-05-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
|
|
US7871607B2
(en)
|
2003-03-05 |
2011-01-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
|
|
US20050129671A1
(en)
|
2003-03-11 |
2005-06-16 |
City Of Hope |
Mammalian antigen-presenting T cells and bi-specific T cells
|
|
EP1648512A4
(en)
|
2003-07-31 |
2009-01-21 |
Immunomedics Inc |
ANTI-CD19 ANTIBODIES
|
|
US7682828B2
(en)
|
2003-11-26 |
2010-03-23 |
Whitehead Institute For Biomedical Research |
Methods for reprogramming somatic cells
|
|
US7442548B2
(en)
|
2004-09-08 |
2008-10-28 |
Wisconsin Alumni Research Foundation |
Culturing human embryonic stem cells in medium containing pipecholic acid and gamma amino butyric acid
|
|
CN109485727A
(zh)
|
2005-05-09 |
2019-03-19 |
小野药品工业株式会社 |
程序性死亡-1(pd-1)的人单克隆抗体及使用抗pd-1抗体来治疗癌症的方法
|
|
EP1951751B1
(en)
|
2005-11-14 |
2017-11-01 |
Merial, Inc. |
Gene therapy for renal failure
|
|
US8278104B2
(en)
|
2005-12-13 |
2012-10-02 |
Kyoto University |
Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2
|
|
US8129187B2
(en)
|
2005-12-13 |
2012-03-06 |
Kyoto University |
Somatic cell reprogramming by retroviral vectors encoding Oct3/4. Klf4, c-Myc and Sox2
|
|
KR101420740B1
(ko)
|
2005-12-13 |
2014-07-17 |
교또 다이가꾸 |
핵초기화 인자
|
|
KR20080098066A
(ko)
|
2006-03-01 |
2008-11-06 |
얀센 파마슈티카 엔.브이. |
림프구 제거제를 ｃｔｌ 및 사이토카인과 결합한 암 치료
|
|
JP5543207B2
(ja)
|
2006-10-04 |
2014-07-09 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
不活性化された人工抗原提示細胞の調製および細胞治療におけるそれらの使用
|
|
EP2137296A2
(en)
|
2007-03-23 |
2009-12-30 |
Wisconsin Alumni Research Foundation |
Somatic cell reprogramming
|
|
PT2856876T
(pt)
|
2007-03-30 |
2018-03-28 |
Memorial Sloan Kettering Cancer Center |
Expressão constitutiva de ligantes co-estimulatórios em linfócitos t adotivamente transferidos
|
|
NZ600758A
(en)
|
2007-06-18 |
2013-09-27 |
Merck Sharp & Dohme |
Antibodies to human programmed death receptor pd-1
|
|
US9683232B2
(en)
|
2007-12-10 |
2017-06-20 |
Kyoto University |
Efficient method for nuclear reprogramming
|
|
US8479118B2
(en)
|
2007-12-10 |
2013-07-02 |
Microsoft Corporation |
Switching search providers within a browser search box
|
|
PL2242773T3
(pl)
|
2008-02-11 |
2017-11-30 |
Cure Tech Ltd. |
Przeciwciała monoklonalne do leczenia nowotworu
|
|
EP2262837A4
(en)
|
2008-03-12 |
2011-04-06 |
Merck Sharp & Dohme |
PD-1 BINDING PROTEINS
|
|
JP5173594B2
(ja)
|
2008-05-27 |
2013-04-03 |
キヤノン株式会社 |
管理装置、画像形成装置及びそれらの処理方法
|
|
EP3447128A1
(en)
|
2008-06-04 |
2019-02-27 |
FUJIFILM Cellular Dynamics, Inc. |
Methods for the production of ips cells using non-viral approach
|
|
WO2010014784A2
(en)
|
2008-08-01 |
2010-02-04 |
Bristol-Myers Squibb Company |
Combination of anti-ctla4 antibody with diverse therapeutic regimens for the synergistic treatment of proliferative diseases
|
|
CN102171348A
(zh)
|
2008-08-12 |
2011-08-31 |
细胞动力国际有限公司 |
产生ips细胞的方法
|
|
CA2735006A1
(en)
|
2008-08-25 |
2010-03-11 |
Amplimmune, Inc. |
Pd-1 antagonists and methods of use thereof
|
|
EP3450545B1
(en)
|
2008-10-24 |
2023-08-23 |
Wisconsin Alumni Research Foundation |
Pluripotent stem cells obtained by non-viral reprogramming
|
|
CN103087991B
(zh)
|
2009-06-05 |
2018-06-12 |
富士胶片细胞动力公司 |
重编程t细胞和造血细胞的方法
|
|
WO2011016588A1
(en)
|
2009-08-07 |
2011-02-10 |
Kyoto University |
Method of efficiently establishing induced pluripotent stem cells
|
|
US8889394B2
(en)
|
2009-09-07 |
2014-11-18 |
Empire Technology Development Llc |
Multiple domain proteins
|
|
ES2539487T3
(es)
|
2009-11-04 |
2015-07-01 |
Cellular Dynamics International, Inc. |
Reprogramación episómica con compuestos químicos
|
|
US20130017199A1
(en)
|
2009-11-24 |
2013-01-17 |
AMPLIMMUNE ,Inc. a corporation |
Simultaneous inhibition of pd-l1/pd-l2
|
|
WO2011090221A1
(en)
|
2010-01-22 |
2011-07-28 |
Kyoto University |
Method for improving induced pluripotent stem cell generation efficiency
|
|
PL2536745T3
(pl)
|
2010-02-19 |
2017-01-31 |
Xencor, Inc. |
Nowe immunoadhezyny CTLA4-IG
|
|
CA2798988C
(en)
|
2010-05-17 |
2020-03-10 |
Sangamo Biosciences, Inc. |
Tal-effector (tale) dna-binding polypeptides and uses thereof
|
|
US8691574B2
(en)
|
2010-06-15 |
2014-04-08 |
Cellular Dynamics International, Inc. |
Generation of induced pluripotent stem cells from small volumes of peripheral blood
|
|
PH12013501201A1
(en)
|
2010-12-09 |
2013-07-29 |
Univ Pennsylvania |
Use of chimeric antigen receptor-modified t cells to treat cancer
|
|
KR101976882B1
(ko)
|
2011-03-23 |
2019-05-09 |
프레드 헛친슨 켄서 리서치 센터 |
세포 면역요법용 방법 및 조성물
|
|
US8398282B2
(en)
|
2011-05-12 |
2013-03-19 |
Delphi Technologies, Inc. |
Vehicle front lighting assembly and systems having a variable tint electrowetting element
|
|
JP6368243B2
(ja)
|
2011-11-11 |
2018-08-08 |
フレッド ハッチンソン キャンサー リサーチ センター |
がんのためのサイクリンａ１に標的化されたｔ細胞免疫療法
|
|
JP6850528B2
(ja)
|
2012-02-13 |
2021-03-31 |
シアトル チルドレンズ ホスピタル ドゥーイング ビジネス アズ シアトル チルドレンズ リサーチ インスティテュート |
二重特異性キメラ抗原受容体およびその治療的使用
|
|
WO2013126726A1
(en)
|
2012-02-22 |
2013-08-29 |
The Trustees Of The University Of Pennsylvania |
Double transgenic t cells comprising a car and a tcr and their methods of use
|
|
RU2665548C2
(ru)
|
2012-05-03 |
2018-08-30 |
Фред Хатчинсон Кансэр Рисёч Сентер |
Способ получения клеток, экспрессирующих т-клеточный рецептор
|
|
CA3133545C
(en)
|
2012-05-25 |
2023-08-08 |
Cellectis |
Use of pre t alpha or functional variant thereof for expanding tcr alpha deficient t cells
|
|
JP2014022858A
(ja)
|
2012-07-17 |
2014-02-03 |
Murata Mfg Co Ltd |
電力増幅器
|
|
PL2884999T3
(pl)
|
2012-08-20 |
2021-07-05 |
Fred Hutchinson Cancer Research Center |
Sposób i kompozycje do immunoterapii komórkowej
|
|
RU2729401C2
(ru)
|
2012-10-02 |
2020-08-06 |
Мемориал Слоан-Кеттеринг Кэнсер Сентер |
Композиции и способы для иммунотерапии
|
|
ES2824024T3
(es)
|
2012-10-10 |
2021-05-11 |
Sangamo Therapeutics Inc |
Compuestos modificadores de células T y usos de los mismos
|
|
US9308236B2
(en)
|
2013-03-15 |
2016-04-12 |
Bristol-Myers Squibb Company |
Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions
|
|
AU2014266833B2
(en)
|
2013-05-13 |
2020-07-02 |
Cellectis |
Methods for engineering highly active T cell for immunotherapy
|
|
CN105682683A
(zh)
|
2013-08-02 |
2016-06-15 |
阿杜罗生物科技控股有限公司 |
结合cd27激动剂以及免疫检查点抑制以用于免疫刺激
|
|
ES2792183T3
(es)
|
2013-09-13 |
2020-11-10 |
Beigene Switzerland Gmbh |
Anticuerpos anti-PD1 y su uso como productos terapéuticos y de diagnóstico
|
|
US20180171298A1
(en)
|
2015-06-30 |
2018-06-21 |
Cellectis |
Methods for improving functionality in nk cell by gene inactivation using specific endonuclease
|
|
EP3971284B1
(en)
|
2015-07-29 |
2023-11-08 |
ONK Therapeutics Limited |
Modified natural killer cells and natural killer cell lines having increased cytotoxicity
|
|
GB2557123B
(en)
*
|
2015-07-31 |
2021-11-03 |
Univ Minnesota |
Modified cells and methods of therapy
|
|
EP3827838B1
(en)
|
2015-12-16 |
2023-06-07 |
The Walter and Eliza Hall Institute of Medical Research |
Inhibition of cytokine-induced sh2 protein in nk cells
|
|
WO2018068135A1
(en)
|
2016-10-12 |
2018-04-19 |
Feldan Bio Inc. |
Rationally-designed synthetic peptide shuttle agents for delivering polypeptide cargos from an extracellular space to the cytosol and/or nucleus of a target eukaryotic cell, uses thereof, methods and kits relating to same
|
|
WO2018115189A1
(en)
*
|
2016-12-21 |
2018-06-28 |
Cellectis |
Stably enginereed proteasome inhibitor resistant immune cells for immunotherapy
|
|
CN110913870A
(zh)
|
2016-12-30 |
2020-03-24 |
细胞结构公司 |
遗传修饰的自然杀伤细胞
|
|
WO2019106163A1
(en)
*
|
2017-12-01 |
2019-06-06 |
Cellectis |
Reprogramming of genetically engineered primary immune cells
|