CN112771167A - 表达有趋化因子的细胞及用途 - Google Patents

表达有趋化因子的细胞及用途 Download PDF

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CN112771167A
CN112771167A CN201980061710.6A CN201980061710A CN112771167A CN 112771167 A CN112771167 A CN 112771167A CN 201980061710 A CN201980061710 A CN 201980061710A CN 112771167 A CN112771167 A CN 112771167A
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cell
antigen
exogenous
receptor
cells
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李宗海
骆红
蒋华
王华茂
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Clegg Medical Co ltd
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Keji Biomedical Shanghai Co ltd
Shanghai Cancer Institute
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Abstract

涉及表达有趋化因子的细胞，所述细胞表达有外源性IL‑21R结合蛋白或外源性IL‑21、和外源性的趋化因子。还提供了表达有外源性受体、外源性IL‑21R结合蛋白或外源性IL‑21、和外源性的趋化因子的细胞，涉及的细胞不仅在体外对实体瘤细胞有效，在体内对实体瘤细胞也具备优异的杀伤效果。

Description

PCT国内申请，说明书已公开。

Claims (30)

  1. PCT国内申请，权利要求书已公开。
CN201980061710.6A 2018-09-20 2019-09-20 表达有趋化因子的细胞及用途 Pending CN112771167A (zh)

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CN201811102138 2018-09-20
CN2018111021387 2018-09-20
CN201811407486 2018-11-23
CN2018114074865 2018-11-23
CN2018115222883 2018-12-13
CN201811522288 2018-12-13
PCT/CN2019/107037 WO2020057641A1 (zh) 2018-09-20 2019-09-20 表达有趋化因子的细胞及用途

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WO2022268162A1 (zh) * 2021-06-23 2022-12-29 科济生物医药（上海）有限公司 治疗肿瘤的方法和组合物
CN116284405A (zh) * 2023-03-15 2023-06-23 中国科学技术大学 靶向cd150蛋白的纳米抗体及其应用

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CN113754778A (zh) * 2020-06-05 2021-12-07 上海交通大学 靶向cldn18.2的嵌合抗原受体及其用途
EP4321533A1 (en) 2021-04-08 2024-02-14 Crage Medical Co., Limited Cellular immunotherapy use
TW202332771A (zh) * 2021-12-21 2023-08-16 大陸商深圳市菲鵬生物治療股份有限公司 轉基因免疫細胞及其構建方法和應用

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CN107109421A (zh) * 2014-10-09 2017-08-29 国立大学法人山口大学 Car表达载体及car表达t细胞
CN107635569A (zh) * 2015-04-30 2018-01-26 南加利福尼亚大学 分泌型tnt car细胞免疫疗法

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022268162A1 (zh) * 2021-06-23 2022-12-29 科济生物医药（上海）有限公司 治疗肿瘤的方法和组合物
CN116284405A (zh) * 2023-03-15 2023-06-23 中国科学技术大学 靶向cd150蛋白的纳米抗体及其应用
CN116284405B (zh) * 2023-03-15 2024-03-19 中国科学技术大学 靶向cd150蛋白的纳米抗体及其应用

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