JPS5925316A - 作用時間の長いスロ−・リリ−ズ薬剤組成物及びその製法 - Google Patents

作用時間の長いスロ−・リリ−ズ薬剤組成物及びその製法

Info

Publication number
JPS5925316A
JPS5925316A JP58111759A JP11175983A JPS5925316A JP S5925316 A JPS5925316 A JP S5925316A JP 58111759 A JP58111759 A JP 58111759A JP 11175983 A JP11175983 A JP 11175983A JP S5925316 A JPS5925316 A JP S5925316A
Authority
JP
Japan
Prior art keywords
tablet
release
salt
composition
base
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP58111759A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0521886B2 (forum.php
Inventor
ベン・オシユラツク
スチユワ−ト・ト−マス・レスリ−
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euro Celtique SA
Original Assignee
Euro Celtique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique SA filed Critical Euro Celtique SA
Publication of JPS5925316A publication Critical patent/JPS5925316A/ja
Publication of JPH0521886B2 publication Critical patent/JPH0521886B2/ja
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP58111759A 1982-06-21 1983-06-21 作用時間の長いスロ−・リリ−ズ薬剤組成物及びその製法 Granted JPS5925316A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US390540 1982-06-21
US06/390,540 US4443428A (en) 1982-06-21 1982-06-21 Extended action controlled release compositions

Publications (2)

Publication Number Publication Date
JPS5925316A true JPS5925316A (ja) 1984-02-09
JPH0521886B2 JPH0521886B2 (forum.php) 1993-03-25

Family

ID=23542881

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58111759A Granted JPS5925316A (ja) 1982-06-21 1983-06-21 作用時間の長いスロ−・リリ−ズ薬剤組成物及びその製法

Country Status (16)

Country Link
US (1) US4443428A (forum.php)
EP (1) EP0097523B1 (forum.php)
JP (1) JPS5925316A (forum.php)
AR (1) AR230783A1 (forum.php)
AT (1) ATE31874T1 (forum.php)
AU (1) AU556588B2 (forum.php)
CA (1) CA1205381A (forum.php)
DE (1) DE3375283D1 (forum.php)
ES (1) ES8500739A1 (forum.php)
IE (1) IE55190B1 (forum.php)
IL (1) IL68887A (forum.php)
MX (1) MX156495A (forum.php)
NZ (1) NZ204438A (forum.php)
PT (1) PT76873B (forum.php)
SE (1) SE8303531D0 (forum.php)
ZA (1) ZA834424B (forum.php)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63122623A (ja) * 1986-10-31 1988-05-26 ユーロセルテイツク・エス・アー 徐放性ヒドロモルホン組成物
JPH04504103A (ja) * 1988-07-01 1992-07-23 ファルマシア・アンド・アップジョン・カンパニー 植込錠から制御放出される抗生物質塩
JP2005506367A (ja) * 2001-10-24 2005-03-03 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 有効物質を徐放する3−(3−ジメチルアミノ−1−エチル−2−メチル−プロピル)フェノール含有医薬

Families Citing this family (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0729927B2 (ja) * 1983-04-09 1995-04-05 日研化学株式会社 テオフィリン徐放性製剤
GB8514665D0 (en) * 1985-06-11 1985-07-10 Eroceltique Sa Oral pharmaceutical composition
EP0225085A1 (en) * 1985-11-13 1987-06-10 ELAN CORPORATION, Plc Controlled absorption pharmaceutical formulation
GB2186485B (en) * 1986-02-13 1988-09-07 Ethical Pharma Ltd Slow release formulation
US4861598A (en) * 1986-07-18 1989-08-29 Euroceltique, S.A. Controlled release bases for pharmaceuticals
US4789549A (en) * 1987-03-09 1988-12-06 Warner-Lambert Company Sustained release dosage forms
WO1989000852A1 (en) * 1987-07-29 1989-02-09 The Upjohn Company Controlled release of antibiotic salts from an implant
GB8813064D0 (en) 1988-06-02 1988-07-06 Euro Celtique Sa Controlled release dosage forms having defined water content
US5612059A (en) * 1988-08-30 1997-03-18 Pfizer Inc. Use of asymmetric membranes in delivery devices
ES2067957T3 (es) * 1990-08-07 1995-04-01 Pfizer Uso de membranas polimerizadas interfacialmente en dispositivos de liberacion.
JP2538134B2 (ja) * 1991-04-08 1996-09-25 田辺製薬株式会社 徐放性製剤およびその製造法
US5266331A (en) * 1991-11-27 1993-11-30 Euroceltique, S.A. Controlled release oxycodone compositions
US5968551A (en) 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5958459A (en) * 1991-12-24 1999-09-28 Purdue Pharma L.P. Opioid formulations having extended controlled released
SE9202250D0 (sv) * 1992-07-29 1992-07-29 Gacell Lab Ab Controlled release morphine preparation
US20080075781A1 (en) * 1992-11-25 2008-03-27 Purdue Pharma Lp Controlled release oxycodone compositions
US5656291A (en) * 1994-03-16 1997-08-12 Pharmacia & Upjohn Aktiebolag Controlled release preparation
SE9301057L (sv) * 1993-03-30 1994-10-01 Pharmacia Ab Beredning med kontrollerad frisättning
AU6552699A (en) * 1993-05-10 2000-03-02 Euro-Celtique S.A. Controlled release formulation
NZ260408A (en) 1993-05-10 1996-05-28 Euro Celtique Sa Controlled release preparation comprising tramadol
US20070275062A1 (en) * 1993-06-18 2007-11-29 Benjamin Oshlack Controlled release oxycodone compositions
IL109944A (en) * 1993-07-01 1998-12-06 Euro Celtique Sa Sustained release dosage unit forms containing morphine and a method of preparing these sustained release dosage unit forms
IL110014A (en) * 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
HU218673B (hu) * 1993-10-07 2000-10-28 Euroceltique S.A. Opioid analgetikumot tartalmazó elnyújtott hatóanyag-felszabadítású orális gyógyszerkészítmény és eljárás előállítására
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5891471A (en) * 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
US5843480A (en) * 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
AUPM814994A0 (en) * 1994-09-14 1994-10-06 Sterling Winthrop Inc. Codeine-containing formulations
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
US20020006438A1 (en) * 1998-09-25 2002-01-17 Benjamin Oshlack Sustained release hydromorphone formulations exhibiting bimodal characteristics
GB9519363D0 (en) 1995-09-22 1995-11-22 Euro Celtique Sa Pharmaceutical formulation
US5811126A (en) * 1995-10-02 1998-09-22 Euro-Celtique, S.A. Controlled release matrix for pharmaceuticals
US5851555A (en) * 1997-08-15 1998-12-22 Fuisz Technologies Ltd. Controlled release dosage forms containing water soluble drugs
HU226730B1 (en) * 1997-12-22 2009-08-28 Euro Celtique Sa Pharmaceutical oral dosage form comprising a combination of an opioid agonist and naltrextone
BR9813826A (pt) * 1997-12-22 2000-10-10 Euro Celtique Sa Potencial de uso abusivo de administração oral de opióide analgésico
US6974590B2 (en) * 1998-03-27 2005-12-13 Cima Labs Inc. Sublingual buccal effervescent
US20030091629A1 (en) * 1998-03-27 2003-05-15 Cima Labs Inc. Sublingual buccal effervescent
US20030118645A1 (en) * 1998-04-29 2003-06-26 Pather S. Indiran Pharmaceutical compositions for rectal and vaginal administration
US20010038855A1 (en) * 1998-06-05 2001-11-08 Desjardin Michael A. Dosage form for administering prescribed dose
US6806294B2 (en) 1998-10-15 2004-10-19 Euro-Celtique S.A. Opioid analgesic
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
MXPA02004293A (es) * 1999-10-29 2002-10-31 Euro Celtique Sa Formulaciones de hidrocodona de liberacion controlada..
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
EP1299104B1 (en) 2000-02-08 2009-05-13 Euro-Celtique S.A. Tamper-resistant oral opioid agonist formulations
DE10029201A1 (de) 2000-06-19 2001-12-20 Basf Ag Verfahren zur Herstellung fester oraler Darreichungsformen mit retardierender Wirkstoffreisetzung
DE10031043A1 (de) * 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
CA2427815C (en) 2000-10-30 2007-07-10 Euro-Celtique S.A. Controlled release hydrocodone formulations
UA81224C2 (uk) * 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
CA2446550C (en) 2001-05-11 2012-03-06 Endo Pharmaceuticals, Inc. Abuse-resistant controlled-release opioid dosage form
US7052706B2 (en) * 2001-06-08 2006-05-30 Nostrum Pharmaceuticals, Inc. Control release formulation containing a hydrophobic material as the sustained release agent
US20030068356A1 (en) * 2001-07-10 2003-04-10 Pather S. Indiran Sequential drug delivery systems
PT1416842E (pt) * 2001-07-18 2009-03-31 Euro Celtique Sa Composições farmacêuticas de oxicodona e naloxona
PT1414451E (pt) 2001-08-06 2009-07-31 Euro Celtique Sa Formulações agonistas de opióides com antagonista libertável e sequestrado
US20030068375A1 (en) 2001-08-06 2003-04-10 Curtis Wright Pharmaceutical formulation containing gelling agent
US20030044458A1 (en) 2001-08-06 2003-03-06 Curtis Wright Oral dosage form comprising a therapeutic agent and an adverse-effect agent
US20030157168A1 (en) * 2001-08-06 2003-08-21 Christopher Breder Sequestered antagonist formulations
US20030060422A1 (en) 2001-08-31 2003-03-27 Balaji Venkataraman Tannate compositions and methods of treatment
US7022342B2 (en) 2002-03-28 2006-04-04 Andrx Corporation, Inc. Controlled release oral dosage form of beta-adrenergic blocking agents
HUE031668T2 (en) 2002-04-05 2017-07-28 Euro Celtique Sa Pharmaceutical composition containing oxycodone and naloxone
ES2677769T3 (es) * 2002-09-20 2018-08-06 Alpharma Pharmaceuticals Llc Subunidad secuestrante y composiciones y procedimientos relacionados
US20040202717A1 (en) * 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
TWI347201B (en) * 2003-04-21 2011-08-21 Euro Celtique Sa Pharmaceutical products,uses thereof and methods for preparing the same
ITMI20032399A1 (it) * 2003-12-09 2005-06-10 Zambon Spa Composizione farmaceutica contenente gabapentina.
WO2005065318A2 (en) * 2003-12-31 2005-07-21 Cima Labs Inc. Effervescent oral opiate dosage form
WO2005065317A2 (en) * 2003-12-31 2005-07-21 Cima Labs Inc. Effervescent oral fentanyl dosage form
PL1708686T3 (pl) * 2003-12-31 2011-08-31 Cima Labs Inc Doustna forma dawkowania fentanylu w postaci musującej o charakterze liniowym oraz sposoby jego podawania
US20050226929A1 (en) * 2004-04-12 2005-10-13 Jianbo Xie Controlled release opioid analgesic formulation
JP2008506788A (ja) * 2004-05-21 2008-03-06 アルザ・コーポレーシヨン 多剤形態の送達用の薬用量形態
EP1604666A1 (en) * 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioids for the treatment of the Chronic Obstructive Pulmonary Disease (COPD)
CA2569958C (en) 2004-06-12 2016-03-22 Jane C. Hirsh Abuse-deterrent drug formulations
US9308164B2 (en) * 2004-06-30 2016-04-12 Sovereign Pharmaceuticals, Llc Hyoscyamine dosage form
US20060110439A1 (en) * 2004-10-22 2006-05-25 Dynamis Therapeutics, Inc. Dermal delivery of n-methyl-glucamine and n-methyl-glucamine compounds
EP1702558A1 (en) * 2005-02-28 2006-09-20 Euro-Celtique S.A. Method and device for the assessment of bowel function
WO2006116247A1 (en) * 2005-04-25 2006-11-02 Teva Pharmaceuticals Usa, Inc. Extended release formulations
US20070160641A1 (en) * 2006-01-12 2007-07-12 Eun-Hyun Jang Coated medical devices and methods of making the same
EP2034975B8 (en) 2006-06-19 2012-05-16 Alpharma Pharmaceuticals, LLC Pharmaceutical compositions
EP2068840A2 (en) * 2006-07-21 2009-06-17 LAB International SRL Hydrophobic abuse deterrent delivery system
EP2224808A4 (en) * 2007-12-17 2013-11-27 Alpharma Pharmaceuticals Llc PHARMACEUTICAL COMPOSITION
US20100151014A1 (en) * 2008-12-16 2010-06-17 Alpharma Pharmaceuticals, Llc Pharmaceutical composition
US8623418B2 (en) * 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
RU2478388C2 (ru) * 2008-07-07 2013-04-10 Еуро-Селтик С.А. Фармацевтическая композиция, содержащая опиоидный антагонист, для лечения задержки мочи
LT2405915T (lt) 2009-03-10 2019-03-12 Euro-Celtique S.A. Greito atpalaidavimo farmacinė kompozicija, apimanti oksikodoną ir naloksoną
US10668060B2 (en) 2009-12-10 2020-06-02 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
CA2690488C (en) * 2010-01-19 2013-06-11 Accucaps Industries Limited Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof
AP2016009016A0 (en) 2010-12-22 2016-01-31 Purdue Pharma Lp Encased tamper resistant controlled release dosage forms
PH12013501345A1 (en) 2010-12-23 2022-10-24 Purdue Pharma Lp Tamper resistant solid oral dosage forms
IN2014DN09238A (forum.php) 2012-04-17 2015-07-10 Purdue Pharma Lp
EA201500742A1 (ru) 2013-02-05 2015-12-30 Пердью Фарма Л.П. Защищенные от нецелевого использования фармацевтические композиции
US10751287B2 (en) 2013-03-15 2020-08-25 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
KR20180037074A (ko) 2013-07-23 2018-04-10 유로-셀티큐 에스.에이. 장내 세균총이상을 초래하고/하거나 장내 박테리아 전위에 대한 위험을 증가시키는 질환과 통증으로 인해 고통받고 있는 환자에서 통증을 치료하는데 사용하기 위한 옥시코돈과 날록손의 조합물
US9849124B2 (en) 2014-10-17 2017-12-26 Purdue Pharma L.P. Systems and methods for treating an opioid-induced adverse pharmacodynamic response
GB201420311D0 (en) 2014-11-14 2014-12-31 Bio Images Drug Delivery Ltd Pharmaceutical processing
GB201420300D0 (en) 2014-11-14 2014-12-31 Bio Images Drug Delivery Ltd Tablet
GB201420306D0 (en) 2014-11-14 2014-12-31 Bio Images Drug Delivery Ltd Compositions
US9737530B1 (en) 2016-06-23 2017-08-22 Collegium Pharmaceutical, Inc. Process of making stable abuse-deterrent oral formulations
WO2019006404A1 (en) 2017-06-30 2019-01-03 Purdue Pharma L.P. METHOD OF TREATMENT AND DOSAGE FORMS

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE856039C (de) * 1944-04-22 1952-11-17 Boehringer & Soehne Gmbh Verfahren zur Darstellung von haltbaren Praeparaten aus Acylsalicylsaeuren und Nebenalkaloiden der Chinarinde
US3400197A (en) * 1965-01-26 1968-09-03 Robins Co Inc A H Compressible sustained release pharmaceutical tablet lipid-colloidal silica gel matrix fragment granules
FR5581M (forum.php) * 1965-06-09 1967-12-04
ES335314A1 (es) * 1966-01-06 1967-12-01 Ceskoslovenska Akademie Ved Mejoras introducidas en la preparacion de vehiculos insolubles de sustancias al menos parcialmente solubles, biologicamente activas.
GB1182179A (en) * 1966-06-22 1970-02-25 Nippon Kayaku Kk Anti-Peptic Ulcer Composition.
DE1617508C3 (de) * 1966-11-16 1974-04-11 Ciba-Geigy Ag, Basel (Schweiz) Antidepressive Mittel
NL148500B (nl) * 1967-10-07 1976-02-16 Scherer Gmbh R P Depotgeneesmiddelen in capsulevorm.
US3525790A (en) * 1968-08-21 1970-08-25 Mortimer D Sackler Dihydroquinidine polygalacturonate and dihydroquinidine galacturonate compositions
US3608063A (en) * 1969-08-15 1971-09-21 Gilbert S Banker Molecular drug entrapment process and compositions
GB1405088A (en) * 1971-06-03 1975-09-03 Mundipharma Ag Slow release formulation
US3965256A (en) * 1972-05-16 1976-06-22 Synergistics Slow release pharmaceutical compositions
US4179497A (en) * 1973-12-17 1979-12-18 Merck & Co., Inc. Solid state ophthalmic medication
FR2255890B1 (forum.php) * 1973-12-28 1978-01-13 Centre Etd Ind Pharma
US4002756A (en) * 1974-04-22 1977-01-11 Interx Research Corporation Useful pro-drug forms of theophylline
US4049791A (en) * 1974-06-21 1977-09-20 Delco Chemical Company, Inc. Prolonged acting appetite suppressant and anti-obesity compositions containing amphetamine adipate, dextroamphetamine adipate, amphetamine sulfate and dextroamphetamine sulfate as the active agents
DE2517434A1 (de) * 1975-04-19 1976-10-28 Artesan Gmbh Fabrik Chemisch P Arzneimittel
SE418247B (sv) * 1975-11-17 1981-05-18 Haessle Ab Sett att framstella kroppar med reglerad frigoring av en aktiv komponent
US4077407A (en) * 1975-11-24 1978-03-07 Alza Corporation Osmotic devices having composite walls
US4014334A (en) * 1976-02-02 1977-03-29 Alza Corporation Laminated osmotic system for dispensing beneficial agent
US4160452A (en) * 1977-04-07 1979-07-10 Alza Corporation Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina
DE2717062C2 (de) * 1977-04-18 1982-11-25 Karl O. Helm Ag, 2000 Hamburg Arzneimittel mit antitussiver Wirkung
GB1561204A (en) * 1977-06-01 1980-02-13 Ici Ltd Sustained release pharmaceutical composition
ZA801654B (en) * 1979-03-21 1981-10-28 M Embrey Controlled release compositions
US4248858A (en) * 1979-08-09 1981-02-03 American Home Products Corporation Sustained release pharmaceutical compositions
US4304765A (en) * 1980-10-14 1981-12-08 Alza Corporation Ocular insert housing steroid in two different therapeutic forms

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63122623A (ja) * 1986-10-31 1988-05-26 ユーロセルテイツク・エス・アー 徐放性ヒドロモルホン組成物
JPH04504103A (ja) * 1988-07-01 1992-07-23 ファルマシア・アンド・アップジョン・カンパニー 植込錠から制御放出される抗生物質塩
JP2005506367A (ja) * 2001-10-24 2005-03-03 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 有効物質を徐放する3−(3−ジメチルアミノ−1−エチル−2−メチル−プロピル)フェノール含有医薬
JP2010280697A (ja) * 2001-10-24 2010-12-16 Gruenenthal Gmbh 有効物質を徐放する3−(3−ジメチルアミノ−1−エチル−2−メチル−プロピル)フェノール含有医薬
JP4758064B2 (ja) * 2001-10-24 2011-08-24 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 有効物質を徐放する3−(3−ジメチルアミノ−1−エチル−2−メチル−プロピル)フェノール含有医薬

Also Published As

Publication number Publication date
MX156495A (es) 1988-08-30
CA1205381A (en) 1986-06-03
EP0097523A3 (en) 1984-12-12
SE8303531D0 (sv) 1983-06-20
PT76873A (fr) 1983-07-01
AR230783A1 (es) 1984-07-31
ES523427A0 (es) 1984-11-01
IE55190B1 (en) 1990-06-20
EP0097523A2 (en) 1984-01-04
DE3375283D1 (en) 1988-02-18
IE831448L (en) 1983-12-21
ES8500739A1 (es) 1984-11-01
PT76873B (fr) 1986-01-27
AU1570883A (en) 1984-01-05
JPH0521886B2 (forum.php) 1993-03-25
IL68887A (en) 1987-07-31
IL68887A0 (en) 1983-10-31
US4443428A (en) 1984-04-17
NZ204438A (en) 1985-05-31
EP0097523B1 (en) 1988-01-13
AU556588B2 (en) 1986-11-13
ZA834424B (en) 1984-03-28
ATE31874T1 (de) 1988-01-15

Similar Documents

Publication Publication Date Title
JPS5925316A (ja) 作用時間の長いスロ−・リリ−ズ薬剤組成物及びその製法
AT398165B (de) Verfahren zur herstellung einer pharmazeutischen kapsel zur oralen verabreichung mit verzögerter wirkstofffreisetzung bzw. kombinierter verzögerter/rascher wirkstofffreisetzung
BE1014449A6 (nl) Farmaceutische verbindingen omvattende amlodipine maleaat.
CZ236094A3 (en) Soft gelatinous pellet and process for preparing thereof
RO106953B1 (ro) COMPRIMATE CU COLESTIRAMINã ©I PROCEDEU DE OB¦INERE A ACESTORA
JPS5914446B2 (ja) ニフエジピン含有固形製剤及びその製造方法
CN103298345B (zh) 组合
JP2013189463A (ja) 製剤
JPS60178815A (ja) 制癌剤
Khalid et al. Formulation and evaluation of rofecoxib liquisolid tablets
JPS61501202A (ja) アセトアミノフェン・ゼラチンカプセル
JPS5854122B2 (ja) 新規なエルゴットアルカロイド薬剤およびその製法
DE2806707A1 (de) Nichtklebende zusammensetzungen aus quaternaeren ionenpolymeren und verfahren zu ihrer herstellung
JP5721093B2 (ja) 崩壊錠
JPS5927820A (ja) スロクチジルを含有する徐放性製品
JPS5982311A (ja) セフアレキシン持効性製剤
JPS5944311A (ja) 徐放性顆粒およびその製造法
EP2471520B1 (en) Pharmaceutical compositions of levetiracetam
JPS60255737A (ja) ジヒドロピリジン調製物
JPH10226644A (ja) 医薬組成物
CN100393312C (zh) 霉酚酸或其类似物的软胶囊及其制备方法
JP2524497B2 (ja) 持続性固形剤
KR100505898B1 (ko) 철분함유 고밀도 펠렛 조성물 및 이의 제조방법
KR101012903B1 (ko) 나노입자 형성을 이용하는 리세드로네이트 경질캡슐
JPS6137723A (ja) 安定なアミノフイリン坐剤