JPS58128323A - ヒトモノクロ−ン抗体の製造法 - Google Patents

ヒトモノクロ−ン抗体の製造法

Info

Publication number
JPS58128323A
JPS58128323A JP58009241A JP924183A JPS58128323A JP S58128323 A JPS58128323 A JP S58128323A JP 58009241 A JP58009241 A JP 58009241A JP 924183 A JP924183 A JP 924183A JP S58128323 A JPS58128323 A JP S58128323A
Authority
JP
Japan
Prior art keywords
cells
hybridoma
cell line
human
hybridoma cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP58009241A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0365148B2 (enExample
Inventor
グンナ−・ラルス・オエシユトベルク
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of JPS58128323A publication Critical patent/JPS58128323A/ja
Publication of JPH0365148B2 publication Critical patent/JPH0365148B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/166—Animal cells resulting from interspecies fusion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/108—Orthomyxoviridae (F), e.g. influenza virus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP58009241A 1982-01-22 1983-01-21 ヒトモノクロ−ン抗体の製造法 Granted JPS58128323A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH409/82A CH652145A5 (de) 1982-01-22 1982-01-22 Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen.
CH409/82 1982-01-22

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2267500A Division JPH03236794A (ja) 1982-01-22 1990-10-03 ヒトモノクローン抗体の製造法
JP3157731A Division JPH0789909B2 (ja) 1982-01-22 1991-05-30 ハイブリドーマセルラインの製造法

Publications (2)

Publication Number Publication Date
JPS58128323A true JPS58128323A (ja) 1983-07-30
JPH0365148B2 JPH0365148B2 (enExample) 1991-10-09

Family

ID=4186382

Family Applications (3)

Application Number Title Priority Date Filing Date
JP58009241A Granted JPS58128323A (ja) 1982-01-22 1983-01-21 ヒトモノクロ−ン抗体の製造法
JP2267500A Granted JPH03236794A (ja) 1982-01-22 1990-10-03 ヒトモノクローン抗体の製造法
JP3157731A Expired - Lifetime JPH0789909B2 (ja) 1982-01-22 1991-05-30 ハイブリドーマセルラインの製造法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2267500A Granted JPH03236794A (ja) 1982-01-22 1990-10-03 ヒトモノクローン抗体の製造法
JP3157731A Expired - Lifetime JPH0789909B2 (ja) 1982-01-22 1991-05-30 ハイブリドーマセルラインの製造法

Country Status (17)

Country Link
US (1) US4634664A (enExample)
JP (3) JPS58128323A (enExample)
AT (1) AT388932B (enExample)
CH (1) CH652145A5 (enExample)
CY (1) CY1488A (enExample)
DE (1) DE3301249A1 (enExample)
DK (1) DK23183A (enExample)
FI (1) FI83538C (enExample)
FR (1) FR2522679B1 (enExample)
GB (1) GB2113715B (enExample)
HK (1) HK52589A (enExample)
IL (1) IL67721A (enExample)
IT (1) IT1160468B (enExample)
KE (1) KE3884A (enExample)
MY (1) MY8700169A (enExample)
SE (1) SE502344C2 (enExample)
SG (1) SG28189G (enExample)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6024184A (ja) * 1983-03-09 1985-02-06 スロ−ン−ケツタリング・インステイテユ−ト・フオ−・キヤンサ−・リサ−チ ガン細胞に対するヒトのモノクロ−ン抗体の反応
WO1986002092A1 (fr) * 1984-09-28 1986-04-10 Teijin Limited Hybridome homme-souris produisant un anticorps humain antiviral, procede de preparation et anticorps monoclonal humain antiviral
JPS6187630A (ja) * 1984-10-08 1986-05-06 Teijin Ltd 単純ヘルペスウイルスに対するヒトモノクロ−ナル抗体及びその製造法
JPS61155398A (ja) * 1984-12-28 1986-07-15 Teijin Ltd 抗緑膿菌ヒトモノクロ−ナル抗体及びその製造法並びにそれを有効成分とする治療剤
JPS6272627A (ja) * 1985-09-27 1987-04-03 Teijin Ltd 単純ヘルペスウイルス感染症の予防又は治療剤
JPS62187417A (ja) * 1985-12-10 1987-08-15 ジエネテイツク　システムズ　コ−ポレ−シヨン 緑膿菌血清型に対する交さ反応性かつ交さ防御性単クロ−ン性抗体
JPH01101896A (ja) * 1987-10-14 1989-04-19 Teijin Ltd カンジダに対するヒト・モノクローナル抗体とその製造法
JPH04211364A (ja) * 1991-02-07 1992-08-03 Teijin Ltd サイトメガロウイルスに対するヒト・モノクローナル抗体を産生するハイブリドーマ
JPH05260961A (ja) * 1992-05-21 1993-10-12 Teijin Ltd サイトメガロウイルスに対するヒト・モノクローナル抗体を産生するハイブリドーマ
JPH05276984A (ja) * 1991-09-05 1993-10-26 Teijin Ltd カンジダに対するヒト・モノクローナル抗体を産生するハイブリドーマ

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* Cited by examiner, † Cited by third party
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CA1247538A (en) * 1982-05-21 1988-12-28 Mark C. Glassy Human-human hybridomas for solid tumors
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US4764465A (en) * 1984-04-26 1988-08-16 Cetus Corporation Human monoclonal antibody against group A red blood cells
US4693975A (en) * 1984-11-20 1987-09-15 The Wistar Institute Human hybridroma fusion partner for production of human monoclonal antibodies
US4677070A (en) * 1985-04-26 1987-06-30 Cetus Corporation Pseudomonas aeruginosa exotoxin A antibodies, their preparation and use
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WO1987005929A1 (en) * 1986-04-01 1987-10-08 Genelabs Incorporated Immortalized cells which produce tissue-specific products
JPS63502962A (ja) * 1986-04-01 1988-11-02 ジーンラブズ　インコーポレイテッド ウイルス特異的な永久増殖性組織細胞
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US5215913A (en) * 1987-11-30 1993-06-01 Roger Williams General Hospital IgG-1 human monoclonal antibody reactive with an HIV-1 antigen and methods of use
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Cited By (10)

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JPS6024184A (ja) * 1983-03-09 1985-02-06 スロ−ン−ケツタリング・インステイテユ−ト・フオ−・キヤンサ−・リサ−チ ガン細胞に対するヒトのモノクロ−ン抗体の反応
WO1986002092A1 (fr) * 1984-09-28 1986-04-10 Teijin Limited Hybridome homme-souris produisant un anticorps humain antiviral, procede de preparation et anticorps monoclonal humain antiviral
JPS6187630A (ja) * 1984-10-08 1986-05-06 Teijin Ltd 単純ヘルペスウイルスに対するヒトモノクロ−ナル抗体及びその製造法
JPS61155398A (ja) * 1984-12-28 1986-07-15 Teijin Ltd 抗緑膿菌ヒトモノクロ−ナル抗体及びその製造法並びにそれを有効成分とする治療剤
JPS6272627A (ja) * 1985-09-27 1987-04-03 Teijin Ltd 単純ヘルペスウイルス感染症の予防又は治療剤
JPS62187417A (ja) * 1985-12-10 1987-08-15 ジエネテイツク　システムズ　コ−ポレ−シヨン 緑膿菌血清型に対する交さ反応性かつ交さ防御性単クロ−ン性抗体
JPH01101896A (ja) * 1987-10-14 1989-04-19 Teijin Ltd カンジダに対するヒト・モノクローナル抗体とその製造法
JPH04211364A (ja) * 1991-02-07 1992-08-03 Teijin Ltd サイトメガロウイルスに対するヒト・モノクローナル抗体を産生するハイブリドーマ
JPH05276984A (ja) * 1991-09-05 1993-10-26 Teijin Ltd カンジダに対するヒト・モノクローナル抗体を産生するハイブリドーマ
JPH05260961A (ja) * 1992-05-21 1993-10-12 Teijin Ltd サイトメガロウイルスに対するヒト・モノクローナル抗体を産生するハイブリドーマ

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DK23183D0 (da) 1983-01-20
IT8319234A0 (it) 1983-01-21
ATA19583A (de) 1989-02-15
FI830190L (fi) 1983-07-23
FI830190A0 (fi) 1983-01-20
SE8300290L (sv) 1983-07-23
DE3301249A1 (de) 1983-09-22
JPH0690753A (ja) 1994-04-05
FI83538C (fi) 1991-07-25
FI83538B (fi) 1991-04-15
GB2113715A (en) 1983-08-10
US4634664A (en) 1987-01-06
GB8301384D0 (en) 1983-02-23
KE3884A (en) 1989-08-11
AT388932B (de) 1989-09-25
FR2522679B1 (fr) 1986-05-09
SE502344C2 (sv) 1995-10-09
JPH0365148B2 (enExample) 1991-10-09
DE3301249C2 (enExample) 1990-04-05
DK23183A (da) 1983-07-23
IL67721A (en) 1986-04-29
JPH0789909B2 (ja) 1995-10-04
SG28189G (en) 1989-08-11
IL67721A0 (en) 1983-05-15
HK52589A (en) 1989-07-07
CH652145A5 (de) 1985-10-31
FR2522679A1 (fr) 1983-09-09
IT1160468B (it) 1987-03-11
JPH0471520B2 (enExample) 1992-11-13
JPH03236794A (ja) 1991-10-22
GB2113715B (en) 1986-06-04
SE8300290D0 (sv) 1983-01-20
MY8700169A (en) 1987-12-31
CY1488A (en) 1989-12-08

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