JPS57132895A - Production of rearranged dna molecule and protein - Google Patents

Production of rearranged dna molecule and protein

Info

Publication number
JPS57132895A
JPS57132895A JP56216094A JP21609481A JPS57132895A JP S57132895 A JPS57132895 A JP S57132895A JP 56216094 A JP56216094 A JP 56216094A JP 21609481 A JP21609481 A JP 21609481A JP S57132895 A JPS57132895 A JP S57132895A
Authority
JP
Japan
Prior art keywords
protein
production
dna molecule
rearranged dna
rearranged
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56216094A
Other languages
English (en)
Inventor
Parubua Irutsuka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of JPS57132895A publication Critical patent/JPS57132895A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2408Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411Amylases
    • C12N9/2414Alpha-amylase (3.2.1.1.)
    • C12N9/2417Alpha-amylase (3.2.1.1.) from microbiological source
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/55Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/61Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP56216094A 1980-12-31 1981-12-29 Production of rearranged dna molecule and protein Pending JPS57132895A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI804081A FI64813C (fi) 1980-12-31 1980-12-31 Foerfarande foer producering av ett utvalt aeggviteaemne och vid foerfarandet anvaenda rekombinantplasmidvektorer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2102749A Division JPH03206889A (ja) 1980-12-31 1990-04-18 組み換えdna分子

Publications (1)

Publication Number Publication Date
JPS57132895A true JPS57132895A (en) 1982-08-17

Family

ID=8514019

Family Applications (2)

Application Number Title Priority Date Filing Date
JP56216094A Pending JPS57132895A (en) 1980-12-31 1981-12-29 Production of rearranged dna molecule and protein
JP2102749A Pending JPH03206889A (ja) 1980-12-31 1990-04-18 組み換えdna分子

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2102749A Pending JPH03206889A (ja) 1980-12-31 1990-04-18 組み換えdna分子

Country Status (11)

Country Link
US (2) US5010000A (ja)
JP (2) JPS57132895A (ja)
AT (1) AT380695B (ja)
BE (1) BE891659A (ja)
CA (1) CA1211726A (ja)
CH (2) CH668080A5 (ja)
DE (2) DE3152001A1 (ja)
FI (1) FI64813C (ja)
FR (2) FR2501230B1 (ja)
GB (2) GB2091268B (ja)
SE (2) SE452632B (ja)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5939899A (ja) * 1982-08-27 1984-03-05 Gakuzo Tamura 新規ベクタ−
JPS59132892A (ja) * 1983-01-12 1984-07-31 カイロン コーポレイション 真核生物における分泌発現遺伝子
JPS609487A (ja) * 1983-06-29 1985-01-18 Kunio Yamane 組換dna分子
JPS6058074A (ja) * 1983-09-09 1985-04-04 Juzo Udaka バチルス・ブレビスを形質転換する方法
JPS6091980A (ja) * 1983-07-06 1985-05-23 ジェネックス・コーポレイション プロテア−ゼ酵素の発現のための徴生物を製造する方法
JPS6137099A (ja) * 1984-07-30 1986-02-21 Wakunaga Seiyaku Kk 蛋白質の製造法
JPS61158790A (ja) * 1984-12-28 1986-07-18 Rikagaku Kenkyusho 新規プラスミド及びその調製方法並びにそのプラスミドを含有する新規微生物
JPS61212288A (ja) * 1985-03-19 1986-09-20 Agency Of Ind Science & Technol 蛋白製造法
JPS61268183A (ja) * 1985-05-24 1986-11-27 Wakamoto Pharmaceut Co Ltd Dna,組換体dnaおよびそれらを含む微生物
JPS623796A (ja) * 1985-06-28 1987-01-09 Ajinomoto Co Inc インタ−ロイキン2の製造法
JPS6229982A (ja) * 1985-07-30 1987-02-07 Rikagaku Kenkyusho 新規プラスミド及びそれにより形質転換された新規微生物
JPS62122589A (ja) * 1985-11-25 1987-06-03 Agency Of Ind Science & Technol Dna塩基配列およびベクタ−

Families Citing this family (63)

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CH657141A5 (de) * 1980-07-01 1986-08-15 Hoffmann La Roche Dns-sequenzen, rekombinante expressionsvektoren zur mikrobiellen herstellung von human-leukozyten-interferonen und transformierte mikroorganismen.
US5380653A (en) * 1980-12-31 1995-01-10 The Finnish National Public Health Institute Expression vectors and methods for intracellular protein production in bascillus
BR8202422A (pt) * 1981-04-29 1983-04-12 Biogen Nv Vetor de clonacao de bacillus processo para sua construcao molecula de dna recombinante processo para sua construcao e processo para a producao de um polipeptidio
AU561343B2 (en) * 1981-10-19 1987-05-07 Genentech Inc. Human immune interferon by recombinant dna
US5582824A (en) * 1981-10-19 1996-12-10 Genentech, Inc. Recombinant DES-CYS-TYR-CYS human immune interferon
WO1983002896A1 (en) * 1982-02-17 1983-09-01 D'antonio, Lawrence, E. Method for the purification of parasite antigenic factors
FR2524487B1 (fr) * 1982-04-05 1985-11-22 Pasteur Institut Fragments d'adn codant pour des polypeptides contenant au moins un determinant antigenique des papillomavirus, notamment du type hpv 1a et polypeptides correspondants
US6936694B1 (en) 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
SE8204811L (sv) * 1982-08-23 1984-02-24 Sven Lofdahl Dna-fragment innefattande en signalsekvens
IT1156317B (it) * 1982-09-08 1987-02-04 Anic Spa Vettori plasmidici ad espressione in bacillus subtilis e procedimento per la loro preparazione
FR2537602B2 (fr) * 1982-09-24 1986-10-24 Centre Nat Rech Scient Nouvel adn recombinant perfectionne utile dans la preparation d'a-amylase par bacillus subtilis
DE3330003A1 (de) * 1982-10-21 1984-10-31 Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig Dna-sequenz und dna-strukturen und sie verwendendes verfahren zur herstellung von penicillin-acylase
EP0108301B2 (en) * 1982-11-01 1993-09-01 SOLVAY ENZYMES, INC. (a Delaware corporation) Method of heterologous cloning of gene in bacillus microorganism
AU569722B2 (en) * 1983-01-28 1988-02-18 Saramane Pty Ltd Expression of plasmodium falciparum polypeptides from cloned cdna
NO840200L (no) * 1983-01-28 1984-07-30 Cefus Corp Glukoamylase cdna.
SE8300693L (sv) * 1983-02-09 1984-08-10 Sven Lofdahl Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta
EP0316023B1 (en) * 1983-03-08 1993-06-09 Rikagaku Kenkyusho Plasmids, methods for their construction, microorganisms carrying them and methods for the extracellular production of xylanase by cultivation of the microorganisms
JPS59196092A (ja) * 1983-04-25 1984-11-07 Sanraku Inc 組換えプラスミドによる耐熱性α−アミラ−ゼの新規製造法
US4859600A (en) * 1983-04-25 1989-08-22 Genentech, Inc. Recombinant procaryotic cell containing correctly processed human growth hormone
US4755465A (en) * 1983-04-25 1988-07-05 Genentech, Inc. Secretion of correctly processed human growth hormone in E. coli and Pseudomonas
US5310675A (en) * 1983-06-24 1994-05-10 Genencor, Inc. Procaryotic carbonyl hydrolases
US4554250A (en) * 1983-06-30 1985-11-19 E. R. Squibb & Sons, Inc. Method of increased production of penicillin acylase and plasmid employed therein
ES8608579A1 (es) * 1983-07-06 1986-06-16 Gist Brocades Nv Procedimiento para introducir dna en un anfitrion de cepa de microorganismo unicelular
CA1311429C (en) * 1983-07-06 1992-12-15 Vasantha Nagarajan Vector for polypeptides in bacilli
US5624829A (en) * 1984-07-03 1997-04-29 Gist-Brocades, B.V. Transformed industrial bacillus strains and methods for making and using them
US4536477A (en) * 1983-08-17 1985-08-20 Cpc International Inc. Thermostable glucoamylase and method for its production
AU561372B2 (en) * 1983-10-10 1987-05-07 Board Of Regents Of The University Of Oklahoma, The Streptokinase-coding recombinant vectors
MX9203641A (es) * 1983-12-16 1992-07-01 Genentech Inc Interferones gamma recombinantes que poseen estabilidad mejorada y metodos biotecnologicos para su obtencion.
DD250546A1 (de) * 1983-12-16 1987-10-14 Adw Ddr Verfahren zur fermentativen herstellung einer streptokinase
US4855238A (en) * 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
US4784949A (en) * 1984-04-19 1988-11-15 Cetus Corporation Universal dominant selectable marker cassette
JPS60188093A (ja) * 1984-03-09 1985-09-25 Teruhiko Beppu 枯草菌に於ける形質発現プラスミド
JPS60188070A (ja) * 1984-03-09 1985-09-25 Kunio Yamane シグナルペプチドをコードするdna
GB8414271D0 (en) * 1984-06-05 1984-07-11 Cpc International Inc Recombinant dna
US6022950A (en) * 1984-06-07 2000-02-08 Seragen, Inc. Hybrid molecules having translocation region and cell-binding region
US5668255A (en) * 1984-06-07 1997-09-16 Seragen, Inc. Hybrid molecules having translocation region and cell-binding region
US4801537A (en) * 1984-06-08 1989-01-31 Genex Corporation Vector for expression of polypeptides in bacilli
JPH062074B2 (ja) * 1984-07-27 1994-01-12 國男 山根 オリゴペプチドの製法
US5691181A (en) * 1984-08-21 1997-11-25 Celltech Limited DNA encoding lipase from human gastric mucosal tissue
GB8421210D0 (en) * 1984-08-21 1984-09-26 Celltech Ltd Polypeptide and polypeptide composition
US5126264A (en) * 1984-09-11 1992-06-30 The Walter & Eliza Hall Institute Of Medical Research The RESA and FIRA antigens of plasmodium falciparum
US4963495A (en) * 1984-10-05 1990-10-16 Genentech, Inc. Secretion of heterologous proteins
IT1177378B (it) * 1984-12-11 1987-08-26 Anic Spa Vettore plasmidico psm112 ad espressione in bacillus subtilis
JPS61177996A (ja) * 1985-02-02 1986-08-09 Green Cross Corp:The インタ−フエロン−γの製造法
US4783415A (en) * 1985-03-28 1988-11-08 Meiji Seika Kabushiki Kaisha Gene coding for signal peptides and utilization thereof
AU5668486A (en) * 1985-03-29 1986-10-23 Biotechnica International Inc. Secretion vector
SE459503B (sv) * 1985-05-03 1989-07-10 Excorim Kommanditbolag Hybrid-dna-molekyl innefattande dna-sekvens som kodar foer protein g samt foerfarande foer framstaellning av protein g
FR2586428B1 (fr) * 1985-08-26 1988-11-25 Pasteur Institut Polypeptides et anticorps, caracteristiques du papillomavirus et leurs applications au diagnostic in vitro, a la prevention et/ou la lutte contre des infections a papillomavirus
US5024943A (en) * 1985-11-07 1991-06-18 Gist-Brocades Regulatory region cloning and analysis plasmid for bacillus
US5278059A (en) * 1985-12-04 1994-01-11 Kabushiki Kaisha Hayashibara Seibutsu Kagaki Kenkyujo Polypeptide possessing cyclomaltodextrin glucanotransferase activity
GB2191491B (en) * 1986-04-25 1990-12-05 Labofina Sa Dna segment coding for a specific lipase, vectors for the expression thereof, microorganisms transformed by these vectors and use of these microorganisms for
US5486473A (en) * 1986-05-06 1996-01-23 The Research Foundation For Microbial Diseases Of Osaka University A DNA coding for a Flavivirus antigen
US5200509A (en) * 1987-04-06 1993-04-06 Celtrix Pharmaceuticals, Inc. Human somatomedin carrier protein subunits and process for producing them; recombinant DNA molecules, hosts, processes and human somatomedin carrier protein-like polypeptides
US5885770A (en) * 1987-04-22 1999-03-23 Institut Pasteur Polypeptides and antibodies characteristic of papillomavirus, and diagnostic procedures and vaccines making use of them
AU5027890A (en) * 1989-02-10 1990-09-05 Genesit Oy A method for producing pertussis toxin subunits
WO1990009448A1 (en) * 1989-02-10 1990-08-23 Genesit Oy Novel expression vectors and methods for intracellular protein production
US5162207A (en) * 1989-07-07 1992-11-10 E. I. Du Pont De Nemours And Company Sucrose inducible expression vectors for bacillus sp.
DK16490D0 (da) * 1990-01-19 1990-01-19 Novo Nordisk As Enzym
NL9001388A (nl) * 1990-06-19 1992-01-16 Unilever Nv Recombinant dna, cel die daarvan afgeleid dna bevat, enzym waarvoor het recombinant dna codeert en toepassingen daarvan.
US5705362A (en) * 1992-05-25 1998-01-06 Gist-Brocades, N.V. Modified signal sequences
US5712118A (en) * 1993-09-29 1998-01-27 Research Foundation Of State University Of New York Vaccine for branhamella catarrhalis
US6121427A (en) * 1994-10-24 2000-09-19 Connaught Laboratories Limited Major outer membrane protein CD of branhamella
US20160367620A1 (en) 2015-06-19 2016-12-22 Harry B. Demopoulos Glutathione

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JPS5519092A (en) * 1978-06-08 1980-02-09 Harvard College Selected protein producing method
JPS6446111A (en) * 1987-08-13 1989-02-20 Nissan Motor Controller for autonomously-traveling vehicle

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AU545912B2 (en) * 1980-03-10 1985-08-08 Cetus Corporation Cloned heterologous jive products in bacillies
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JPS5519092A (en) * 1978-06-08 1980-02-09 Harvard College Selected protein producing method
JPS6446111A (en) * 1987-08-13 1989-02-20 Nissan Motor Controller for autonomously-traveling vehicle

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5939899A (ja) * 1982-08-27 1984-03-05 Gakuzo Tamura 新規ベクタ−
JPS59132892A (ja) * 1983-01-12 1984-07-31 カイロン コーポレイション 真核生物における分泌発現遺伝子
JPH0372893A (ja) * 1983-01-12 1991-03-28 Chiron Corp 酵母による組換ポリペプチドの製造方法
JPS609487A (ja) * 1983-06-29 1985-01-18 Kunio Yamane 組換dna分子
JPS6091980A (ja) * 1983-07-06 1985-05-23 ジェネックス・コーポレイション プロテア−ゼ酵素の発現のための徴生物を製造する方法
JPH0156756B2 (ja) * 1983-09-09 1989-12-01 Juzo Udaka
JPS6058074A (ja) * 1983-09-09 1985-04-04 Juzo Udaka バチルス・ブレビスを形質転換する方法
JPS6137099A (ja) * 1984-07-30 1986-02-21 Wakunaga Seiyaku Kk 蛋白質の製造法
JP2524693B2 (ja) * 1984-07-30 1996-08-14 湧永製薬株式会社 蛋白質の製造法
JPS61158790A (ja) * 1984-12-28 1986-07-18 Rikagaku Kenkyusho 新規プラスミド及びその調製方法並びにそのプラスミドを含有する新規微生物
JPH0817702B2 (ja) * 1984-12-28 1996-02-28 理化学研究所 新規プラスミド及びその調製方法並びにそのプラスミドを含有する新規微生物
JPS61212288A (ja) * 1985-03-19 1986-09-20 Agency Of Ind Science & Technol 蛋白製造法
JPS61268183A (ja) * 1985-05-24 1986-11-27 Wakamoto Pharmaceut Co Ltd Dna,組換体dnaおよびそれらを含む微生物
JPS623796A (ja) * 1985-06-28 1987-01-09 Ajinomoto Co Inc インタ−ロイキン2の製造法
JPS6229982A (ja) * 1985-07-30 1987-02-07 Rikagaku Kenkyusho 新規プラスミド及びそれにより形質転換された新規微生物
JPS62122589A (ja) * 1985-11-25 1987-06-03 Agency Of Ind Science & Technol Dna塩基配列およびベクタ−

Also Published As

Publication number Publication date
FI804081L (fi) 1982-07-01
FI64813B (fi) 1983-09-30
FR2526040B1 (fr) 1985-08-30
GB2133408B (en) 1985-01-30
CA1211726A (en) 1986-09-23
SE8702885D0 (sv) 1987-07-16
BE891659A (fr) 1982-04-16
SE453513B (sv) 1988-02-08
SE452632B (sv) 1987-12-07
GB2133408A (en) 1984-07-25
DE3152001A1 (de) 1982-07-29
SE8107812L (sv) 1982-07-01
FI64813C (fi) 1984-01-10
US5010015A (en) 1991-04-23
CH668080A5 (de) 1988-11-30
CH659480A5 (de) 1987-01-30
SE8702885L (sv) 1987-07-16
GB2091268B (en) 1984-12-05
FR2501230B1 (fr) 1985-09-13
US5010000A (en) 1991-04-23
FR2501230A1 (fr) 1982-09-10
GB8332576D0 (en) 1984-01-11
DE3152001C2 (ja) 1992-05-21
JPH03206889A (ja) 1991-09-10
ATA560181A (de) 1985-11-15
GB2091268A (en) 1982-07-28
FR2526040A1 (fr) 1983-11-04
DE3153403C2 (ja) 1992-01-02
AT380695B (de) 1986-06-25

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