|
US4357311A
(en)
*
|
1980-10-03 |
1982-11-02 |
Warner-Lambert Company |
Substrate for immunoassay and means of preparing same
|
|
YU43849B
(en)
*
|
1983-08-09 |
1989-12-31 |
Akad Wissenschaften |
Process for preparing macromolecular substances with chemically active filling substances
|
|
US4719176A
(en)
*
|
1983-10-31 |
1988-01-12 |
Klotz Irving M |
Enzyme-free diagnostic binding reagents
|
|
US4693985A
(en)
*
|
1984-08-21 |
1987-09-15 |
Pall Corporation |
Methods of concentrating ligands and active membranes used therefor
|
|
US4970300A
(en)
*
|
1985-02-01 |
1990-11-13 |
New York University |
Modified factor VIII
|
|
DE3515586A1
(de)
*
|
1985-04-30 |
1986-11-06 |
Boehringer Mannheim Gmbh, 6800 Mannheim |
Stabilisiertes sarcosinoxidase-praeparat
|
|
US4886836A
(en)
*
|
1987-06-03 |
1989-12-12 |
Pall Corporation |
Activated medium with low non-specific protein adsorption
|
|
US5001048A
(en)
*
|
1987-06-05 |
1991-03-19 |
Aurthur D. Little, Inc. |
Electrical biosensor containing a biological receptor immobilized and stabilized in a protein film
|
|
US5192507A
(en)
*
|
1987-06-05 |
1993-03-09 |
Arthur D. Little, Inc. |
Receptor-based biosensors
|
|
US5160626A
(en)
*
|
1987-09-14 |
1992-11-03 |
Gelman Sciences Inc. |
Blotting methods using polyaldehyde activated membranes
|
|
US4961852A
(en)
*
|
1987-09-14 |
1990-10-09 |
Gelman Sciences, Inc. |
Polyaldehyde activated membranes
|
|
US4992172A
(en)
*
|
1987-09-14 |
1991-02-12 |
Gelman Sciences, Inc. |
Blotting methods using polyaldehyde activated membranes
|
|
DE68928907T2
(de)
*
|
1988-10-17 |
1999-09-16 |
Hemasure,Inc. |
Verfahren zur kovalenten oberflächen-modifikation hydrophober polymere und erzeugnisse daraus
|
|
JPH02219571A
(ja)
*
|
1989-02-20 |
1990-09-03 |
Kanebo Ltd |
修飾プロテアーゼ及びその製造法
|
|
US5116964A
(en)
|
1989-02-23 |
1992-05-26 |
Genentech, Inc. |
Hybrid immunoglobulins
|
|
WO1990012092A1
(de)
*
|
1989-04-04 |
1990-10-18 |
Fritz Pittner |
Verfahren zum immobilisieren von proteinen, peptiden, coenzymen od.dgl. an einem träger
|
|
DE4005927A1
(de)
*
|
1990-02-25 |
1991-08-29 |
Roehm Gmbh |
Immobilisierung von proteinen an traegern
|
|
US5133968A
(en)
*
|
1990-08-20 |
1992-07-28 |
Kanebo, Ltd. |
Modified protease, method of producing the same and cosmetic products containing the modified protease
|
|
US5436147A
(en)
*
|
1991-03-01 |
1995-07-25 |
Nucleic Assays Corporation |
Heterobifunctional crosslinked agents for immobilizing molecules on plastic substrates
|
|
US5279955A
(en)
*
|
1991-03-01 |
1994-01-18 |
Pegg Randall K |
Heterofunctional crosslinking agent for immobilizing reagents on plastic substrates
|
|
GB2267502B
(en)
*
|
1992-05-28 |
1997-01-22 |
Aligena Ag |
Polymeric reaction products for use in immobilized buffered gels and membranes
|
|
IL104734A0
(en)
*
|
1993-02-15 |
1993-06-10 |
Univ Bar Ilan |
Bioactive conjugates of cellulose with amino compounds
|
|
JP2871435B2
(ja)
*
|
1993-04-22 |
1999-03-17 |
イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー |
親水性ポリマー被覆パーフルオロカーボンポリマーベースのマトリックスの製造方法
|
|
PT739355E
(pt)
*
|
1994-01-11 |
2005-01-31 |
Dyax Corp |
Proteinas de 'dominio de kunitz' inibidoras de calicreina e seus analogos
|
|
US6057287A
(en)
*
|
1994-01-11 |
2000-05-02 |
Dyax Corp. |
Kallikrein-binding "Kunitz domain" proteins and analogues thereof
|
|
US6045797A
(en)
*
|
1994-03-14 |
2000-04-04 |
New York University Medical Center |
Treatment or diagnosis of diseases or conditions associated with a BLM domain
|
|
US5877016A
(en)
|
1994-03-18 |
1999-03-02 |
Genentech, Inc. |
Human trk receptors and neurotrophic factor inhibitors
|
|
US5561097A
(en)
*
|
1994-04-28 |
1996-10-01 |
Minnesota Mining And Manufacturing Company |
Method of controlling density of ligand coupled onto supports and products produced therefrom
|
|
US5708142A
(en)
|
1994-05-27 |
1998-01-13 |
Genentech, Inc. |
Tumor necrosis factor receptor-associated factors
|
|
US5837524A
(en)
*
|
1994-12-15 |
1998-11-17 |
Sugen, Inc. |
PYK2 related polynucleotide products
|
|
US5837815A
(en)
*
|
1994-12-15 |
1998-11-17 |
Sugen, Inc. |
PYK2 related polypeptide products
|
|
US5807989A
(en)
*
|
1994-12-23 |
1998-09-15 |
New York University |
Methods for treatment or diagnosis of diseases or disorders associated with an APB domain
|
|
US6300482B1
(en)
|
1995-01-03 |
2001-10-09 |
Max-Flanck-Gesellschaft Zuer For{Overscore (D)}Erung Der |
MDKI, a novel receptor tyrosine kinase
|
|
US7005505B1
(en)
|
1995-08-25 |
2006-02-28 |
Genentech, Inc. |
Variants of vascular endothelial cell growth factor
|
|
US6020473A
(en)
*
|
1995-08-25 |
2000-02-01 |
Genentech, Inc. |
Nucleic acids encoding variants of vascular endothelial cell growth factor
|
|
EP0871729A1
(en)
|
1995-09-15 |
1998-10-21 |
Baylor College Of Medicine |
Steroid receptor coactivator compositions and methods of use
|
|
US6046048A
(en)
*
|
1996-01-09 |
2000-04-04 |
Genetech, Inc. |
Apo-2 ligand
|
|
US6030945A
(en)
*
|
1996-01-09 |
2000-02-29 |
Genentech, Inc. |
Apo-2 ligand
|
|
US20050089958A1
(en)
*
|
1996-01-09 |
2005-04-28 |
Genentech, Inc. |
Apo-2 ligand
|
|
US6998116B1
(en)
|
1996-01-09 |
2006-02-14 |
Genentech, Inc. |
Apo-2 ligand
|
|
CA2242911A1
(en)
|
1996-01-16 |
1997-07-24 |
Kay C. Dee |
Peptides for altering osteoblast adhesion
|
|
EP0904366A1
(en)
*
|
1996-04-01 |
1999-03-31 |
Genentech, Inc. |
Apo-2li and apo-3 apoptosis polypeptides
|
|
US20020165157A1
(en)
*
|
1996-04-01 |
2002-11-07 |
Genentech, Inc. |
Apo-2LI and Apo-3 polypeptides
|
|
US6100071A
(en)
|
1996-05-07 |
2000-08-08 |
Genentech, Inc. |
Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production
|
|
US6159462A
(en)
*
|
1996-08-16 |
2000-12-12 |
Genentech, Inc. |
Uses of Wnt polypeptides
|
|
US5851984A
(en)
*
|
1996-08-16 |
1998-12-22 |
Genentech, Inc. |
Method of enhancing proliferation or differentiation of hematopoietic stem cells using Wnt polypeptides
|
|
US6462176B1
(en)
|
1996-09-23 |
2002-10-08 |
Genentech, Inc. |
Apo-3 polypeptide
|
|
US20040241645A1
(en)
*
|
1997-01-31 |
2004-12-02 |
Genentech, Inc. |
O-fucosyltransferase
|
|
AU729158B2
(en)
|
1997-01-31 |
2001-01-25 |
Genentech Inc. |
O-fucosyltransferase
|
|
US20020102706A1
(en)
*
|
1997-06-18 |
2002-08-01 |
Genentech, Inc. |
Apo-2DcR
|
|
US20100152426A1
(en)
*
|
1997-05-15 |
2010-06-17 |
Ashkenazi Avi J |
Apo-2 receptor fusion proteins
|
|
US6342369B1
(en)
*
|
1997-05-15 |
2002-01-29 |
Genentech, Inc. |
Apo-2-receptor
|
|
ATE516354T1
(de)
|
1997-05-15 |
2011-07-15 |
Genentech Inc |
Apo-2-rezeptor
|
|
CA2293724C
(en)
|
1997-06-05 |
2010-02-02 |
Xiaodong Wang |
Apaf-1, the ced-4 human homolog, an activator of caspase-3
|
|
CA2293740A1
(en)
*
|
1997-06-18 |
1998-12-23 |
Genentech, Inc. |
Apo-2dcr, a tnf-related receptor
|
|
AU8569698A
(en)
*
|
1997-07-11 |
1999-02-08 |
Brandeis University |
Method of inducing apoptosis by reducing the level of thiamin
|
|
US20030175856A1
(en)
*
|
1997-08-26 |
2003-09-18 |
Genetech, Inc. |
Rtd receptor
|
|
ES2331900T3
(es)
*
|
1997-08-26 |
2010-01-19 |
Genentech, Inc. |
Receptor rtd.
|
|
US8679534B2
(en)
*
|
1997-12-12 |
2014-03-25 |
Andrx Labs, Llc |
HMG-CoA reductase inhibitor extended release formulation
|
|
ATE411385T1
(de)
|
1998-01-15 |
2008-10-15 |
Genentech Inc |
Apo-2 ligand
|
|
WO1999064461A2
(en)
*
|
1998-06-12 |
1999-12-16 |
Genentech, Inc. |
Monoclonal antibodies, cross-reactive antibodies and method for producing the same
|
|
US6984719B1
(en)
|
1998-09-17 |
2006-01-10 |
Hospital Sainte-Justine |
Peptide antagonists of prostaglandin F2α receptor
|
|
US6368793B1
(en)
*
|
1998-10-14 |
2002-04-09 |
Microgenomics, Inc. |
Metabolic selection methods
|
|
DK2319928T3
(da)
*
|
1998-10-23 |
2013-06-24 |
Kirin Amgen Inc |
Dimere trombopoietiske peptidomimetika, der binder til MPL-receptor og har trombopoietisk aktivitet
|
|
US6660843B1
(en)
*
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
|
US6982153B1
(en)
|
1998-12-03 |
2006-01-03 |
Targanta Therapeutics, Inc. |
DNA sequences from staphylococcus aureus bacteriophage 77 that encode anti-microbial polypeptides
|
|
US6861442B1
(en)
*
|
1998-12-30 |
2005-03-01 |
Sugen, Inc. |
PYK2 and inflammation
|
|
KR20020026460A
(ko)
|
1999-06-16 |
2002-04-10 |
게리 엘. 윌콕스 |
인체 폴리(adp-리보스) 폴리메라제 2 물질 및 방법
|
|
US20040235749A1
(en)
*
|
1999-09-15 |
2004-11-25 |
Sylvain Chemtob |
G-protein coupled receptor antagonists
|
|
US20030138771A1
(en)
*
|
1999-09-30 |
2003-07-24 |
Jerry Pelletier |
DNA sequences from S. pneumoniae bacteriophage DP1 that encode anti-microbal polypeptides
|
|
US6808902B1
(en)
|
1999-11-12 |
2004-10-26 |
Amgen Inc. |
Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
|
|
AU774575C
(en)
*
|
1999-11-16 |
2005-09-08 |
Genentech Inc. |
Elisa for VEGF
|
|
FR2803926B1
(fr)
*
|
2000-01-14 |
2002-04-05 |
Thomson Csf Sextant |
Procede de generation automatique de table de symboles d'un calculateur temps reel
|
|
JP4541490B2
(ja)
*
|
2000-04-07 |
2010-09-08 |
株式会社カネカ |
拡張型心筋症用吸着体
|
|
ATE319737T1
(de)
|
2000-04-21 |
2006-03-15 |
Amgen Inc |
Peptidderivate des apolipoproteins-a1/aii
|
|
US6667300B2
(en)
*
|
2000-04-25 |
2003-12-23 |
Icos Corporation |
Inhibitors of human phosphatidylinositol 3-kinase delta
|
|
US6677136B2
(en)
|
2000-05-03 |
2004-01-13 |
Amgen Inc. |
Glucagon antagonists
|
|
US6911204B2
(en)
*
|
2000-08-11 |
2005-06-28 |
Favrille, Inc. |
Method and composition for altering a B cell mediated pathology
|
|
EP1309373A2
(en)
*
|
2000-08-11 |
2003-05-14 |
Favrille, Inc. |
Method and composition for altering a t cell mediated pathology
|
|
JP4516719B2
(ja)
|
2001-05-11 |
2010-08-04 |
アムジエン・インコーポレーテツド |
Tall−1と結合するペプチド及び関連分子
|
|
US7332474B2
(en)
*
|
2001-10-11 |
2008-02-19 |
Amgen Inc. |
Peptides and related compounds having thrombopoietic activity
|
|
US7138370B2
(en)
|
2001-10-11 |
2006-11-21 |
Amgen Inc. |
Specific binding agents of human angiopoietin-2
|
|
US20040054082A1
(en)
*
|
2001-12-03 |
2004-03-18 |
Bank David H |
Toughened polymer blends with improved surface properties
|
|
US20100311954A1
(en)
*
|
2002-03-01 |
2010-12-09 |
Xencor, Inc. |
Optimized Proteins that Target Ep-CAM
|
|
US7153829B2
(en)
*
|
2002-06-07 |
2006-12-26 |
Dyax Corp. |
Kallikrein-inhibitor therapies
|
|
CA2488558C
(en)
*
|
2002-06-07 |
2013-08-20 |
Dyax Corp. |
Prevention and reduction of blood loss
|
|
US7521530B2
(en)
|
2002-06-11 |
2009-04-21 |
Universite De Montreal |
Peptides and peptidomimetics useful for inhibiting the activity of prostaglandin F2α receptor
|
|
ES2709103T3
(es)
|
2002-08-28 |
2019-04-15 |
Dyax Corp |
Métodos para conservar órganos y tejidos
|
|
US6919426B2
(en)
|
2002-09-19 |
2005-07-19 |
Amgen Inc. |
Peptides and related molecules that modulate nerve growth factor activity
|
|
WO2005016348A1
(en)
*
|
2003-08-14 |
2005-02-24 |
Icos Corporation |
Method of inhibiting immune responses stimulated by an endogenous factor
|
|
WO2005016349A1
(en)
*
|
2003-08-14 |
2005-02-24 |
Icos Corporation |
Methods of inhibiting leukocyte accumulation
|
|
US8883147B2
(en)
|
2004-10-21 |
2014-11-11 |
Xencor, Inc. |
Immunoglobulins insertions, deletions, and substitutions
|
|
US8399618B2
(en)
|
2004-10-21 |
2013-03-19 |
Xencor, Inc. |
Immunoglobulin insertions, deletions, and substitutions
|
|
US20060134105A1
(en)
*
|
2004-10-21 |
2006-06-22 |
Xencor, Inc. |
IgG immunoglobulin variants with optimized effector function
|
|
US20050113458A1
(en)
*
|
2003-10-22 |
2005-05-26 |
Forest Laboratories, Inc. |
Use of 1-aminocyclohexane derivatives to modify deposition of fibrillogenic a-beta peptides in amyloidopathies
|
|
WO2005066621A1
(en)
*
|
2003-12-30 |
2005-07-21 |
3M Innovative Properties Company |
Surface acoustic wave sensor assemblies
|
|
US7658994B2
(en)
*
|
2003-12-30 |
2010-02-09 |
3M Innovative Properties Company |
Substrates and compounds bonded thereto
|
|
EP1711805A2
(en)
*
|
2003-12-30 |
2006-10-18 |
3M Innovative Properties Company |
Detection cartridges, modules, systems and methods
|
|
US20070065490A1
(en)
*
|
2003-12-30 |
2007-03-22 |
Schaberg Mark S |
Substrates and compounds bonded thereto
|
|
DE602005027673D1
(de)
*
|
2004-03-05 |
2011-06-09 |
Vegenics Pty Ltd |
Materialien und verfahren für wachstumsfaktorbindende konstrukte
|
|
EP1745288A2
(en)
*
|
2004-04-16 |
2007-01-24 |
Genentech, Inc. |
Assay for antibodies
|
|
PL1761540T3
(pl)
|
2004-05-13 |
2017-06-30 |
Icos Corporation |
Chinazolinony jako inhibitory ludzkiej kinazy 3-fosfatydyloinozytolu delta
|
|
CA2562800A1
(en)
*
|
2004-05-15 |
2005-12-01 |
Genentech, Inc. |
Cross-screening system and methods for detecting a molecule having binding affinity for a target molecule
|
|
JP2008500338A
(ja)
*
|
2004-05-25 |
2008-01-10 |
イコス・コーポレイション |
造血細胞の異常増殖を治療及び/又は予防する方法
|
|
CA2572765C
(en)
*
|
2004-07-08 |
2013-05-21 |
Amgen Inc. |
Compound having improved bioefficiency when administered in a multidose regimen
|
|
GB0416699D0
(en)
*
|
2004-07-27 |
2004-09-01 |
Prometic Biosciences Ltd |
Prion protein ligands and methods of use
|
|
CN101103045B
(zh)
|
2004-09-24 |
2015-11-25 |
安姆根有限公司 |
修饰的Fc分子
|
|
US7235530B2
(en)
*
|
2004-09-27 |
2007-06-26 |
Dyax Corporation |
Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
|
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
DK1817340T3
(da)
|
2004-11-12 |
2012-08-13 |
Xencor Inc |
Fc-varianter med ændret binding til fcrn
|
|
JP2008525041A
(ja)
|
2004-12-22 |
2008-07-17 |
ジェネンテック・インコーポレーテッド |
可溶性多膜貫通型タンパク質の産生方法
|
|
EP1885356A2
(en)
*
|
2005-02-17 |
2008-02-13 |
Icos Corporation |
Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
|
|
BRPI0611811A2
(pt)
*
|
2005-06-10 |
2008-12-09 |
Prometic Biosciences Ltd |
ligantes de ligaÇço À proteÍna
|
|
US7557190B2
(en)
|
2005-07-08 |
2009-07-07 |
Xencor, Inc. |
Optimized proteins that target Ep-CAM
|
|
US8008453B2
(en)
|
2005-08-12 |
2011-08-30 |
Amgen Inc. |
Modified Fc molecules
|
|
US20070161089A1
(en)
*
|
2005-11-08 |
2007-07-12 |
Genentech, Inc. |
Method of Producing Pan-Specific Antibodies
|
|
PE20070684A1
(es)
|
2005-11-14 |
2007-08-06 |
Amgen Inc |
MOLECULAS QUIMERICAS DE ANTICUERPO RANKL-PTH/PTHrP
|
|
US7276480B1
(en)
|
2005-12-30 |
2007-10-02 |
Dyax Corp. |
Prevention and reduction of blood loss
|
|
WO2007102946A2
(en)
|
2006-01-23 |
2007-09-13 |
Amgen Inc. |
Crystalline polypeptides
|
|
CA2643693A1
(en)
*
|
2006-03-10 |
2007-09-20 |
Dyax Corp. |
Formulations for ecallantide
|
|
JO3324B1
(ar)
|
2006-04-21 |
2019-03-13 |
Amgen Inc |
مركبات علاجية مجففة بالتبريد تتعلق بالعصارة الهضمية
|
|
US7981425B2
(en)
|
2006-06-19 |
2011-07-19 |
Amgen Inc. |
Thrombopoietic compounds
|
|
ES2376396T3
(es)
|
2006-06-26 |
2012-03-13 |
Amgen Inc. |
Método para tratar aterosclerosis.
|
|
AU2007357448B2
(en)
|
2006-09-18 |
2012-09-06 |
Compugen Ltd |
Bioactive peptides and method of using same
|
|
US7833527B2
(en)
|
2006-10-02 |
2010-11-16 |
Amgen Inc. |
Methods of treating psoriasis using IL-17 Receptor A antibodies
|
|
MX2009003562A
(es)
|
2006-10-04 |
2009-04-15 |
Genentech Inc |
Ensayo elisa para la deteccion de vegf.
|
|
US20090252703A1
(en)
*
|
2006-10-19 |
2009-10-08 |
Gegg Jr Colin V |
Use of alcohol co-solvents to improve pegylation reaction yields
|
|
PE20081140A1
(es)
*
|
2006-10-25 |
2008-09-22 |
Amgen Inc |
Agentes terapeuticos a base de peptidos derivados de toxinas
|
|
WO2008079322A1
(en)
*
|
2006-12-22 |
2008-07-03 |
Beckman Coulter, Inc. |
Methods, kits and materials for diagnosing disease states by measuring isoforms or proforms of myeloperoxidase
|
|
US20100151553A1
(en)
*
|
2006-12-29 |
2010-06-17 |
Bjork Jason W |
Method of detection of bioanalytes by acousto-mechanical detection systems comprising the addition of liposomes
|
|
JP5591691B2
(ja)
|
2007-05-22 |
2014-09-17 |
アムジエン・インコーポレーテツド |
生物活性を有する融合タンパク質を作製するための組成物及び方法
|
|
EP2167534B1
(en)
|
2007-07-12 |
2012-07-04 |
Compugen Ltd. |
Bioactive peptides and method of using same
|
|
MY159075A
(en)
|
2007-07-26 |
2016-12-15 |
Amgen Inc |
Modified lecithin-cholesterol acyltransferase enzymes
|
|
EP2201024A1
(en)
|
2007-08-28 |
2010-06-30 |
Ramot At Tel Aviv University |
Peptides inducing a cd4i conformation in hiv gp120 while retaining vacant cd4 binding site
|
|
PL2808343T3
(pl)
|
2007-12-26 |
2019-11-29 |
Xencor Inc |
Warianty Fc ze zmienionym wiązaniem do FcRn
|
|
WO2010027802A2
(en)
*
|
2008-08-25 |
2010-03-11 |
New York University |
Methods for treating diabetic wounds
|
|
US9492449B2
(en)
|
2008-11-13 |
2016-11-15 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
|
NZ631024A
(en)
|
2008-11-13 |
2016-04-29 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
|
US8637454B2
(en)
*
|
2009-01-06 |
2014-01-28 |
Dyax Corp. |
Treatment of mucositis with kallikrein inhibitors
|
|
SG174529A1
(en)
|
2009-03-24 |
2011-10-28 |
Gilead Calistoga Llc |
Atropisomers of2-purinyl-3-tolyl-quinazolinone derivatives and methods of use
|
|
PT2421536E
(pt)
*
|
2009-04-20 |
2015-10-20 |
Gilead Calistoga Llc |
Métodos de tratamento para tumores sólidos
|
|
EP2456443A1
(en)
|
2009-07-21 |
2012-05-30 |
Gilead Calistoga LLC |
Treatment of liver disorders with pi3k inhibitors
|
|
TW201117824A
(en)
|
2009-10-12 |
2011-06-01 |
Amgen Inc |
Use of IL-17 receptor a antigen binding proteins
|
|
WO2011049625A1
(en)
|
2009-10-20 |
2011-04-28 |
Mansour Samadpour |
Method for aflatoxin screening of products
|
|
EP2494356B1
(en)
*
|
2009-10-26 |
2017-03-15 |
Genentech, Inc. |
Assays for detecting antibodies specific to therapeutic anti-ige antibodies and their use in anaphylaxis
|
|
PT2496567T
(pt)
|
2009-11-05 |
2017-11-15 |
Rhizen Pharmaceuticals S A |
Novos moduladores de quinase benzopiran
|
|
RS62853B1
(sr)
|
2010-01-06 |
2022-02-28 |
Takeda Pharmaceuticals Co |
Proteini koji vezuju kalikrein plazme
|
|
WO2011097527A2
(en)
|
2010-02-04 |
2011-08-11 |
Xencor, Inc. |
Immunoprotection of therapeutic moieties using enhanced fc regions
|
|
US20110189178A1
(en)
*
|
2010-02-04 |
2011-08-04 |
Xencor, Inc. |
Immunoprotection of Therapeutic Moieties Using Enhanced Fc Regions
|
|
WO2011116026A2
(en)
|
2010-03-15 |
2011-09-22 |
The Board Of Trustees Of The University Of Illinois |
Inhibitors of beta integrin-g protein alpha subunit binding interactions
|
|
ES2715611T3
(es)
|
2010-05-17 |
2019-06-05 |
Incozen Therapeutics Pvt Ltd |
Compuestos novedosos de 3H-imidazo[4,5-b]piridina-3,5-disustituida y 3H-[1,2,3]triazolo[4,5-b]piridina 3,5-disustituida como moduladores de proteína cinasas
|
|
EP2582382B1
(en)
|
2010-06-17 |
2017-04-19 |
New York University |
Cosmetic uses and applications of calreticulin
|
|
WO2012030738A2
(en)
|
2010-08-30 |
2012-03-08 |
Beckman Coulter, Inc. |
Complex phosphoprotein activation profiles
|
|
WO2012045085A1
(en)
|
2010-10-01 |
2012-04-05 |
Oxford Biotherapeutics Ltd. |
Anti-rori antibodies
|
|
EP2655401B1
(en)
|
2010-12-20 |
2016-03-09 |
The Regents of the University of Michigan |
Inhibitors of the epidermal growth factor receptor-heat shock protein 90 binding interaction
|
|
JOP20210044A1
(ar)
|
2010-12-30 |
2017-06-16 |
Takeda Pharmaceuticals Co |
الأجسام المضادة لـ cd38
|
|
AU2012204202A1
(en)
|
2011-01-06 |
2013-07-11 |
Dyax Corp. |
Plasma kallikrein binding proteins
|
|
SG10201601789TA
(en)
|
2011-03-16 |
2016-04-28 |
Amgen Inc |
Potent And Selective Inhibitors Of Nav1.3 And Nav1.7
|
|
JP2014516944A
(ja)
|
2011-04-29 |
2014-07-17 |
ブリストル−マイヤーズ スクイブ カンパニー |
Ip10抗体の用量漸増計画
|
|
RS58326B1
(sr)
|
2011-05-04 |
2019-03-29 |
Rhizen Pharmaceuticals S A |
Nova jedinjenja kao modulatori proteinskih kinaza
|
|
WO2013016220A1
(en)
|
2011-07-22 |
2013-01-31 |
Amgen Inc. |
Il-17 receptor a is required for il-17c biology
|
|
CN104136461B
(zh)
|
2011-09-22 |
2021-06-08 |
安姆根有限公司 |
Cd27l抗原结合蛋白
|
|
US12466897B2
(en)
|
2011-10-10 |
2025-11-11 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
|
AP2014007875A0
(en)
|
2012-03-05 |
2014-08-31 |
Gilead Calistoga Llc |
Polymorphic forms of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
|
|
WO2013142796A2
(en)
|
2012-03-23 |
2013-09-26 |
Bristol-Myers Squibb Company |
Methods of treatments using ctla4 antibodies
|
|
BR112014024023A2
(pt)
|
2012-03-28 |
2017-07-18 |
Genentech Inc |
anticorpos idiotípicos anti-hcmv e usos dos mesmos
|
|
CN107082779A
(zh)
|
2012-03-30 |
2017-08-22 |
理森制药股份公司 |
作为c‑met 蛋白激酶调节剂的新化合物
|
|
WO2013155346A1
(en)
|
2012-04-11 |
2013-10-17 |
The Regents Of The University Of California |
Diagnostic tools for response to 6-thiopurine therapy
|
|
JO3623B1
(ar)
|
2012-05-18 |
2020-08-27 |
Amgen Inc |
البروتينات المرتبطة بمولد المستضاد st2
|
|
TW201425336A
(zh)
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
Bcma抗原結合蛋白質
|
|
US20160067347A1
(en)
|
2012-12-20 |
2016-03-10 |
Amgen Inc. |
Apj receptor agonists and uses thereof
|
|
ES2728936T3
(es)
|
2013-01-25 |
2019-10-29 |
Amgen Inc |
Anticuerpos dirigidos contra CDH19 para melanoma
|
|
JO3519B1
(ar)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
تركيبات أجسام مضادة لأجل cdh19 و cd3
|
|
AU2014214037A1
(en)
|
2013-02-06 |
2015-07-02 |
Pieris Ag |
Novel lipocalin-mutein assays for measuring hepcidin concentration
|
|
SMT202000088T1
(it)
|
2013-02-18 |
2020-03-13 |
Vegenics Pty Ltd |
Molecole leganti ligandi e relativi usi
|
|
US10344060B2
(en)
|
2013-03-12 |
2019-07-09 |
Amgen Inc. |
Potent and selective inhibitors of Nav1.7
|
|
US9546203B2
(en)
|
2013-03-14 |
2017-01-17 |
Amgen Inc. |
Aglycosylated Fc-containing polypeptides with cysteine substitutions
|
|
SI2970449T1
(sl)
|
2013-03-15 |
2019-11-29 |
Amgen Res Munich Gmbh |
Enoverižne vezavne molekule, ki vsebujejo N-terminalni ABP
|
|
EP4438044A3
(en)
|
2013-03-15 |
2024-12-04 |
Board of Regents, The University of Texas System |
Peptide fttftvt for use in treating fibrosis
|
|
PL3587448T3
(pl)
|
2013-03-15 |
2021-11-29 |
Xencor, Inc. |
Białka heterodimeryczne
|
|
US9505849B2
(en)
|
2013-03-15 |
2016-11-29 |
Amgen Research (Munich) Gmbh |
Antibody constructs for influenza M2 and CD3
|
|
EP3421495A3
(en)
|
2013-03-15 |
2019-05-15 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
|
US9260527B2
(en)
|
2013-03-15 |
2016-02-16 |
Sdix, Llc |
Anti-human CXCR4 antibodies and methods of making same
|
|
CN110511279B
(zh)
|
2013-05-30 |
2024-03-29 |
基尼克萨制药有限公司 |
制瘤素m受体抗原结合蛋白
|
|
EP3042192A4
(en)
*
|
2013-09-04 |
2017-04-26 |
Sten Ohlson |
Weak affinity chromatography
|
|
WO2015036956A1
(en)
|
2013-09-12 |
2015-03-19 |
Institut National De La Sante Et De La Recherche Medicale |
Method for in vitro quantifying allo-antibodies, auto-antibodies and/or therapeutic antibodies
|
|
KR102332302B1
(ko)
|
2013-09-13 |
2021-12-01 |
제넨테크, 인크. |
세포주에서 숙주 세포 단백질 및 재조합 폴리펩티드 생성물을 검출 및 정량화하기 위한 조성물 및 방법
|
|
AR097648A1
(es)
|
2013-09-13 |
2016-04-06 |
Amgen Inc |
Combinación de factores epigenéticos y compuestos biespecíficos que tienen como diana cd33 y cd3 en el tratamiento de leucemia mieloide
|
|
SG10201802525QA
(en)
|
2013-09-13 |
2018-04-27 |
Genentech Inc |
Methods and compositions comprising purified recombinant polypeptides
|
|
HRP20210410T1
(hr)
|
2013-10-11 |
2021-04-30 |
Oxford Bio Therapeutics Limited |
Konjugirana antitijela prema ly75 za liječenje raka
|
|
PT3083630T
(pt)
|
2013-12-20 |
2019-11-15 |
Gilead Calistoga Llc |
Procedimentos para inibidores da fosfatidilinositol 3-quinase
|
|
EP3083623A1
(en)
|
2013-12-20 |
2016-10-26 |
Gilead Calistoga LLC |
Polymorphic forms of a hydrochloride salt of (s) -2-(9h-purin-6-ylamino) propyl) -5-fluoro-3-phenylquinazolin-4 (3h) -one
|
|
WO2015106311A1
(en)
|
2014-01-17 |
2015-07-23 |
Minomic International Ltd. |
Cell surface prostate cancer antigen for diagnosis
|
|
EP3107935B1
(en)
|
2014-02-20 |
2020-06-24 |
Allergan, Inc. |
Complement component c5 antibodies
|
|
SG11201606983SA
(en)
|
2014-02-27 |
2016-09-29 |
Allergan Inc |
COMPLEMENT FACTOR Bb ANTIBODIES
|
|
AU2015235967B2
(en)
|
2014-03-27 |
2020-10-22 |
Takeda Pharmaceutical Company Limited |
Compositions and methods for treatment of diabetic macular edema
|
|
KR102497443B1
(ko)
|
2014-03-28 |
2023-02-08 |
젠코어 인코포레이티드 |
Cd38 및 cd3에 결합하는 이중특이적 항체
|
|
AU2015274574B2
(en)
|
2014-06-10 |
2019-10-10 |
Amgen Inc. |
Apelin polypeptides
|
|
JP6455995B2
(ja)
|
2014-06-13 |
2019-01-23 |
ギリアード サイエンシーズ, インコーポレイテッド |
ホスファチジルイノシトール3−キナーゼ阻害剤
|
|
ES2743809T3
(es)
|
2014-07-31 |
2020-02-20 |
Amgen Res Munich Gmbh |
Constructos de anticuerpo monocatenarios biespecificos específicos de especies cruzadas optimizados
|
|
UY36245A
(es)
|
2014-07-31 |
2016-01-29 |
Amgen Res Munich Gmbh |
Constructos de anticuerpos para cdh19 y cd3
|
|
MX384418B
(es)
|
2014-07-31 |
2025-03-14 |
Amgen Res Munich Gmbh |
Constructo de anticuerpo de cadena individual biespecífico con distribución mejorada de tejido.
|
|
WO2016141387A1
(en)
|
2015-03-05 |
2016-09-09 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
|
ES2761726T3
(es)
|
2015-03-06 |
2020-05-20 |
Hoffmann La Roche |
DsbA y DsbC ultrapurificadas y procedimientos de preparación y uso de las mismas
|
|
WO2016149537A1
(en)
|
2015-03-17 |
2016-09-22 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Bank vole prion protein as a broad-spectrum substrate for rt-quic-based detection and discrimination of prion strains
|
|
IL283764B2
(en)
|
2015-04-10 |
2024-01-01 |
Amgen Inc |
Interleukin-2 muteins for the expansion of t-regulatory cells
|
|
TWI772258B
(zh)
|
2015-04-17 |
2022-08-01 |
德商安美基研究(慕尼黑)公司 |
Cdh3與cd3之雙特異性抗體構築體
|
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Flt3及cd3抗體構築體
|
|
TWI717375B
(zh)
|
2015-07-31 |
2021-02-01 |
德商安美基研究(慕尼黑)公司 |
Cd70及cd3抗體構築體
|
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Egfrviii及cd3抗體構築體
|
|
EA039859B1
(ru)
|
2015-07-31 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
|
TW202346349A
(zh)
|
2015-07-31 |
2023-12-01 |
德商安美基研究(慕尼黑)公司 |
Dll3及cd3抗體構築體
|
|
TWI796283B
(zh)
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Msln及cd3抗體構築體
|
|
EP3932953A1
(en)
|
2015-08-28 |
2022-01-05 |
F. Hoffmann-La Roche AG |
Anti-hypusine antibodies and uses thereof
|
|
CN116077648A
(zh)
|
2015-12-11 |
2023-05-09 |
武田药品工业株式会社 |
血浆激肽释放酶抑制剂及其治疗遗传性血管性水肿发作的用途
|
|
TWI797073B
(zh)
|
2016-01-25 |
2023-04-01 |
德商安美基研究(慕尼黑)公司 |
包含雙特異性抗體建構物之醫藥組合物
|
|
TN2018000266A1
(en)
|
2016-02-03 |
2020-01-16 |
Amgen Res Munich Gmbh |
Psma and cd3 bispecific t cell engaging antibody constructs.
|
|
IL313507A
(en)
|
2016-02-03 |
2024-08-01 |
Amgen Res Munich Gmbh |
Constructs of bispecific antibodies to BCMA and CD3 that bind to T cells, preparations containing the same and uses thereof
|
|
JOP20170091B1
(ar)
|
2016-04-19 |
2021-08-17 |
Amgen Res Munich Gmbh |
إعطاء تركيبة ثنائية النوعية ترتبط بـ cd33 وcd3 للاستخدام في طريقة لعلاج اللوكيميا النخاعية
|
|
CN109071623B
(zh)
|
2016-05-04 |
2022-05-27 |
美国安进公司 |
用于扩增t调节性细胞的白细胞介素-2突变蛋白
|
|
RU2770006C2
(ru)
|
2016-05-16 |
2022-04-14 |
Такеда Фармасьютикал Компани Лимитед |
Антитела к фактору ix padua
|
|
EP3484923A1
(en)
|
2016-07-15 |
2019-05-22 |
Takeda Pharmaceutical Company Limited |
Methods and materials for assessing response to plasmablast- and plasma cell-depleting therapies
|
|
JP7105238B2
(ja)
|
2017-01-18 |
2022-07-22 |
ジェネンテック, インコーポレイテッド |
抗pd-l1抗体に対するイディオタイプ抗体及びそれらの使用
|
|
JOP20190189A1
(ar)
|
2017-02-02 |
2019-08-01 |
Amgen Res Munich Gmbh |
تركيبة صيدلانية ذات درجة حموضة منخفضة تتضمن بنيات جسم مضاد يستهدف الخلية t
|
|
GB201703876D0
(en)
|
2017-03-10 |
2017-04-26 |
Berlin-Chemie Ag |
Pharmaceutical combinations
|
|
AU2018261951B2
(en)
|
2017-05-05 |
2025-05-22 |
Amgen Inc. |
Pharmaceutical composition comprising bispecific antibody constructs for improved storage and administration
|
|
AU2018347521A1
(en)
|
2017-10-12 |
2020-05-07 |
Immunowake Inc. |
VEGFR-antibody light chain fusion protein
|
|
TWI827570B
(zh)
|
2017-12-11 |
2024-01-01 |
美商安進公司 |
雙特異性抗體產品之連續製造製程
|
|
UY38041A
(es)
|
2017-12-29 |
2019-06-28 |
Amgen Inc |
Construcción de anticuerpo biespecífico dirigida a muc17 y cd3
|
|
AU2019264364B2
(en)
|
2018-04-30 |
2024-06-06 |
Medimmune Limited |
Conjugates for targeting and clearing aggregates
|
|
GB201809746D0
(en)
|
2018-06-14 |
2018-08-01 |
Berlin Chemie Ag |
Pharmaceutical combinations
|
|
US11530274B2
(en)
|
2018-07-02 |
2022-12-20 |
Amgen Inc. |
Anti-STEAP1 antigen-binding protein
|
|
MX2021001221A
(es)
|
2018-07-30 |
2021-06-23 |
Amgen Res Munich Gmbh |
Administración prolongada de un constructo de anticuerpo biespecífico que se une a cd33 y cd3.
|
|
AU2019356564A1
(en)
|
2018-10-11 |
2021-04-29 |
Amgen Inc. |
Downstream processing of bispecific antibody constructs
|
|
WO2020081493A1
(en)
|
2018-10-16 |
2020-04-23 |
Molecular Templates, Inc. |
Pd-l1 binding proteins
|
|
EP3983520A1
(en)
|
2019-06-13 |
2022-04-20 |
Amgen, Inc |
Automated biomass-based perfusion control in the manufacturing of biologics
|
|
MX2022001866A
(es)
|
2019-08-13 |
2022-03-11 |
Amgen Inc |
Muteinas de interleucina-2 para la expansion de celulas t reguladoras.
|
|
CA3152946A1
(en)
|
2019-09-10 |
2021-03-18 |
Amgen Inc. |
Purification method for bispecific antigen-binding polypeptides with enhanced protein l capture dynamic binding capacity
|
|
EP4058485A1
(en)
|
2019-11-13 |
2022-09-21 |
Amgen Inc. |
Method for reduced aggregate formation in downstream processing of bispecific antigen-binding molecules
|
|
CN114867749A
(zh)
|
2019-12-17 |
2022-08-05 |
安进公司 |
用于疗法中的双重白介素-2/tnf受体激动剂
|
|
MX2022008649A
(es)
|
2020-01-13 |
2022-09-23 |
Takeda Pharmaceuticals Co |
Inhibidores de calicreina plasmatica y sus usos para tratar episodios de angioedema hereditario pediatrico.
|
|
TW202204420A
(zh)
|
2020-04-30 |
2022-02-01 |
美商建南德克公司 |
Kras特異性抗體及其用途
|
|
EP4153633A1
(en)
|
2020-05-19 |
2023-03-29 |
Amgen Inc. |
Mageb2 binding constructs
|
|
CA3183693A1
(en)
|
2020-05-29 |
2021-12-02 |
Amgen Inc. |
Adverse effects-mitigating administration of a bispecific construct binding to cd33 and cd3
|
|
KR20230017822A
(ko)
|
2020-06-01 |
2023-02-06 |
제넨테크, 인크. |
세포외 소포를 만들기 위한 방법 및 이들의 용도
|
|
WO2021259227A1
(zh)
|
2020-06-23 |
2021-12-30 |
江苏康缘药业股份有限公司 |
抗cd38抗体及其用途
|
|
WO2022013189A1
(en)
|
2020-07-14 |
2022-01-20 |
F. Hoffmann-La Roche Ag |
Assays for fixed dose combinations
|
|
CN116323671A
(zh)
|
2020-11-06 |
2023-06-23 |
安进公司 |
具有增加的选择性的多靶向性双特异性抗原结合分子
|
|
EP4314078A1
(en)
|
2021-04-02 |
2024-02-07 |
Amgen Inc. |
Mageb2 binding constructs
|
|
US20240384006A1
(en)
|
2021-05-06 |
2024-11-21 |
Amgen Research (Munich) Gmbh |
Cd20 and cd22 targeting antigen-binding molecules for use in proliferative diseases
|
|
EP4522651A1
(en)
|
2022-05-12 |
2025-03-19 |
Amgen Research (Munich) GmbH |
Multichain multitargeting bispecific antigen-binding molecules of increased selectivity
|
|
WO2024059675A2
(en)
|
2022-09-14 |
2024-03-21 |
Amgen Inc. |
Bispecific molecule stabilizing composition
|
|
AU2024302269A1
(en)
|
2023-06-14 |
2025-11-13 |
Amgen Inc. |
T cell engager masking molecules
|