JPS5446786A - Novel 3*4*55trihydroxypiperidine compound* its manufacture and use for medicine - Google Patents

Novel 3*4*55trihydroxypiperidine compound* its manufacture and use for medicine

Info

Publication number
JPS5446786A
JPS5446786A JP10297478A JP10297478A JPS5446786A JP S5446786 A JPS5446786 A JP S5446786A JP 10297478 A JP10297478 A JP 10297478A JP 10297478 A JP10297478 A JP 10297478A JP S5446786 A JPS5446786 A JP S5446786A
Authority
JP
Japan
Prior art keywords
medicine
novel
manufacture
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10297478A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6231703B2 (enExample
Inventor
Yunge Bodo
Peetaa Kurauze Hansu
Miyuuraa Ruutsu
Purusu Barutaa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25772626&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPS5446786(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE19772738717 external-priority patent/DE2738717A1/de
Priority claimed from DE19772758025 external-priority patent/DE2758025A1/de
Application filed by Bayer AG filed Critical Bayer AG
Publication of JPS5446786A publication Critical patent/JPS5446786A/ja
Publication of JPS6231703B2 publication Critical patent/JPS6231703B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/132—Heterocyclic compounds containing only one nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/137—Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP10297478A 1977-08-27 1978-08-25 Novel 3*4*55trihydroxypiperidine compound* its manufacture and use for medicine Granted JPS5446786A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19772738717 DE2738717A1 (de) 1977-08-27 1977-08-27 N-alkylierte derivate der 5-amino- 5-deoxy-d-glucose, verfahren zu ihrer herstellung und ihre verwendung
DE19772758025 DE2758025A1 (de) 1977-12-24 1977-12-24 Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung

Publications (2)

Publication Number Publication Date
JPS5446786A true JPS5446786A (en) 1979-04-12
JPS6231703B2 JPS6231703B2 (enExample) 1987-07-09

Family

ID=25772626

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10297478A Granted JPS5446786A (en) 1977-08-27 1978-08-25 Novel 3*4*55trihydroxypiperidine compound* its manufacture and use for medicine

Country Status (19)

Country Link
US (2) US4639436A (enExample)
EP (1) EP0000947B2 (enExample)
JP (1) JPS5446786A (enExample)
AT (1) AT373239B (enExample)
AU (2) AU3921478A (enExample)
CA (1) CA1123437A (enExample)
DE (1) DE2860330D1 (enExample)
DK (1) DK152753C (enExample)
ES (1) ES472838A1 (enExample)
FI (1) FI72715C (enExample)
GR (1) GR73065B (enExample)
HU (1) HU182449B (enExample)
IE (1) IE47070B1 (enExample)
IL (1) IL55423A (enExample)
IT (1) IT1111197B (enExample)
LU (1) LU90211I2 (enExample)
NL (1) NL960027I2 (enExample)
NO (1) NO154918C (enExample)
PT (1) PT68474A (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55164676A (en) * 1979-06-05 1980-12-22 Bayer Ag Novel 3*4*55trihydroxypiperidine compound
JPS5665869A (en) * 1979-10-19 1981-06-03 Bayer Ag Novel 22hydroxyalkyll3*4*55trihydroxyypiperidine compound* its manufacture and drug
JP2005536506A (ja) * 2002-07-17 2005-12-02 オックスフォード グリコサイエンシィズ（ユーケイ）リミテッド グルコシルセラミドシンターゼの阻害剤としてのピペリジントリオール誘導体
JP2008546744A (ja) * 2005-06-23 2008-12-25 サントル ナシオナル ドゥ ラ ルシェルシェ シアンティフィク イミノ糖ファミリーの新規な化合物、リソソーム病の治療のためのその使用、及び、その製造方法
WO2012011174A1 (ja) * 2010-07-22 2012-01-26 ビオフェルミン製薬株式会社 脂質代謝改善剤、脂質代謝改善作用増強剤、抗肥満剤及び抗肥満作用増強剤
JP2013129662A (ja) * 2006-05-24 2013-07-04 United Therapeutics Corp デオキシノジリマイシンおよびｄ−アラビニトールのアナログおよび使用方法

Families Citing this family (240)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5943946B2 (ja) * 1978-04-28 1984-10-25 日本新薬株式会社 Ｎ−アルケニルモラノリン誘導体
DE2839309A1 (de) * 1978-09-09 1980-03-27 Bayer Ag 3,4,5-trihydroxypiperidin-derivate
DE2848117A1 (de) * 1978-11-06 1980-05-14 Bayer Ag Derivate des 2-hydroxymethyl-3,4,5- trihydroxy-piperidins, ihre herstellung und verwendung zur beeinflussung des kohlenhydrat- und fettstoffwechsels
DE2925943A1 (de) * 1979-06-27 1981-01-29 Bayer Ag 1-alkadien-2,4-yl-2-hydroxymethyl3,4,5-trihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE2936240A1 (de) * 1979-09-07 1981-03-26 Bayer Ag, 51373 Leverkusen Verfahren zur herstellung bekannter und neuer 6-amino-6-desoxy-2,3-0-isopropyliden-(alpha)-l-sorbofuranose-derivate sowie neue zwischenprodukte des verfahrens
JPS56108768A (en) * 1980-01-28 1981-08-28 Nippon Shinyaku Co Ltd Cinnamylmoranoline derivative
JPS56108767A (en) * 1980-01-28 1981-08-28 Nippon Shinyaku Co Ltd Bismoranoline derivative
DE3007078A1 (de) * 1980-02-26 1981-09-10 Bayer Ag, 5090 Leverkusen Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel sowie in der tierernaehrung
DE3038901A1 (de) * 1980-10-15 1982-05-06 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von n-substituierten derivaten des 1-desoxynojirimycins
US4634765A (en) * 1984-12-18 1987-01-06 Merrell Dow Pharmaceuticals Inc. Homodisaccharide hypoglycemic agents
DE3507019A1 (de) * 1985-02-28 1986-08-28 Bayer Ag, 5090 Leverkusen Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung
US5231185A (en) * 1985-11-19 1993-07-27 Cornell Research Foundation, Inc. Monosaccharide analog-based glycosidase inhibitors
DE3620645A1 (de) * 1985-12-20 1987-07-02 Bayer Ag 3-amino-4,5-dihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung
DE3611841A1 (de) * 1986-04-09 1987-10-15 Bayer Ag Verfahren zur herstellung von 1-desoxynojirimycin und dessen n-derivaten
DE3737523A1 (de) * 1987-11-05 1989-05-18 Bayer Ag Verwendung von substituierten hydroxypiperidinen als antivirale mittel
US5192772A (en) * 1987-12-09 1993-03-09 Nippon Shinyaku Co. Ltd. Therapeutic agents
AU605661B2 (en) * 1987-12-21 1991-01-17 Monsanto Company Method of inhibiting virus
US4849430A (en) * 1988-03-09 1989-07-18 Monsanto Company Method of inhibiting virus
DE3743749A1 (de) * 1987-12-23 1989-07-13 Bayer Ag Arzneimittel enthaltend in kombination interferon und 1-desoxy-piperidinosen, verfahren zu deren herstellung und deren verwendung
US5250545A (en) * 1988-02-12 1993-10-05 Meiji Seika Kaisha, Ltd. Cancer cell metastasis inhibitor methods
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US5221746A (en) * 1988-11-03 1993-06-22 G. D. Searle & Co. 1,5-dideoxy-1,5-imino-D-glucitol derivatives
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US5100797A (en) * 1989-06-27 1992-03-31 Monsanto Company Fucosidase inhibitors
EP0422307A1 (en) * 1989-10-10 1991-04-17 Merrell Dow Pharmaceuticals Inc. Novel alpha-glucosidase inhibitors
DE3936295A1 (de) * 1989-11-01 1991-05-02 Bayer Ag Verfahren zur herstellung von zwischenprodukten und zur synthese von n-(2-hydroxyethyl)-2-hydroxymethyl-3,4,5-trihydroxypiperidine
US5030638A (en) * 1990-02-26 1991-07-09 G. D. Searle & Co. Method of antiviral enhancement
DE4009561A1 (de) * 1990-03-24 1991-09-26 Bayer Ag Neue desoxynojirimycinderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US5536732A (en) * 1990-04-27 1996-07-16 Merrell Pharmaceuticals Inc. N-derivatives of 1-deoxy nojirimycin
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US5151519A (en) * 1990-05-07 1992-09-29 G. D. Searle & Co. Process for the preparation of 1,5-(alkylimino)-1,5-dideoxy-d-glucitol and derivatives thereof
US5504078A (en) * 1990-06-08 1996-04-02 Merrell Dow Pharmaceuticals Inc. α-glucosidase inhibitors
CA2086413A1 (en) * 1990-06-29 1991-12-30 Yohji Ezure Piperidine derivatives
US5561134A (en) * 1990-09-25 1996-10-01 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties
US5273981A (en) * 1990-10-18 1993-12-28 Monsanto Company Intramolecular carbamate derivative of 2,3-Di-O-blocked-1,4-dideoxy-4-fluoro-nojirimycins
US5128347A (en) * 1990-10-18 1992-07-07 Monsanto Company Glycosidase inhibiting 1,4-dideoxy-4-fluoronojirimycin
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US5216168A (en) * 1992-04-01 1993-06-01 G. D. Searle & Co. 2- and 3- amino and azido derivatives of 1,5-iminosugars
US5331096A (en) * 1992-04-01 1994-07-19 G. D. Searle & Co. 2- and 3-sulfur derivatives of 1,5-iminosugars
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CN101239089A (zh) * 1997-04-15 2008-08-13 Csir公司 具有食欲抑制剂活性的药物组合物
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KR20010040937A (ko) 1998-02-12 2001-05-15 윌리암스 로저 에이 간염 바이러스 감염의 치료를 위한 ｎ-치환된1,5-디데옥시-1,5-이미노-ｄ-글루시톨 화합물의 용도
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CA2320900C (en) 1998-03-19 2009-10-27 Bristol-Myers Squibb Company Biphasic controlled release delivery system for high solubility pharmaceuticals and method
US6274597B1 (en) 1998-06-01 2001-08-14 Mount Sinai School Of Medicine Of New York University Method of enhancing lysosomal α-Galactosidase A
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JPS5513286A (en) * 1978-07-11 1980-01-30 Bayer Ag 11desoxyynodilinmycin and nnsubstituted derivative
JPS5943948A (ja) * 1982-09-03 1984-03-12 Toyota Motor Corp 可変ベンチユリ型気化器

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JPS559051A (en) * 1978-07-06 1980-01-22 Nippon Shinyaku Co Ltd Substituted moranoline derivative
JPS5513286A (en) * 1978-07-11 1980-01-30 Bayer Ag 11desoxyynodilinmycin and nnsubstituted derivative
JPS5943948A (ja) * 1982-09-03 1984-03-12 Toyota Motor Corp 可変ベンチユリ型気化器

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55164676A (en) * 1979-06-05 1980-12-22 Bayer Ag Novel 3*4*55trihydroxypiperidine compound
JPS5665869A (en) * 1979-10-19 1981-06-03 Bayer Ag Novel 22hydroxyalkyll3*4*55trihydroxyypiperidine compound* its manufacture and drug
JPH01131156A (ja) * 1979-10-19 1989-05-24 Bayer Ag ピペリジン誘導体
JP2005536506A (ja) * 2002-07-17 2005-12-02 オックスフォード グリコサイエンシィズ（ユーケイ）リミテッド グルコシルセラミドシンターゼの阻害剤としてのピペリジントリオール誘導体
JP2008546744A (ja) * 2005-06-23 2008-12-25 サントル ナシオナル ドゥ ラ ルシェルシェ シアンティフィク イミノ糖ファミリーの新規な化合物、リソソーム病の治療のためのその使用、及び、その製造方法
JP2013129662A (ja) * 2006-05-24 2013-07-04 United Therapeutics Corp デオキシノジリマイシンおよびｄ−アラビニトールのアナログおよび使用方法
US8975280B2 (en) 2006-05-24 2015-03-10 The Chancellor, Masters And Scholars Of The University Of Oxford Deoxynojirimycin and D-arabinitol analogs and methods of using
WO2012011174A1 (ja) * 2010-07-22 2012-01-26 ビオフェルミン製薬株式会社 脂質代謝改善剤、脂質代謝改善作用増強剤、抗肥満剤及び抗肥満作用増強剤
JP5769710B2 (ja) * 2010-07-22 2015-08-26 ビオフェルミン製薬株式会社 脂質代謝改善剤、脂質代謝改善作用増強剤、抗肥満剤及び抗肥満作用増強剤

Also Published As

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US4260622A (en) 1981-04-07
AU520686B2 (en) 1982-02-18
US4639436A (en) 1987-01-27
FI72715B (fi) 1987-03-31
IE47070B1 (en) 1983-12-14
LU90211I2 (fr) 1998-04-08
DK152753B (da) 1988-05-09
NO154918B (no) 1986-10-06
IE781716L (en) 1979-02-27
CA1123437A (en) 1982-05-11
IT1111197B (it) 1986-01-13
NO154918C (no) 1987-01-14
GR73065B (enExample) 1984-01-30
DE2860330D1 (en) 1981-03-12
DK152753C (da) 1988-10-31
EP0000947B2 (de) 1984-10-10
EP0000947A1 (de) 1979-03-07
IL55423A (en) 1982-09-30
EP0000947B1 (de) 1981-01-14
AT373239B (de) 1983-12-27
DK377678A (da) 1979-02-28
FI72715C (fi) 1987-07-10
JPS6231703B2 (enExample) 1987-07-09
ATA621778A (de) 1983-05-15
IL55423A0 (en) 1978-10-31
FI782607A7 (fi) 1979-02-28
NL960027I1 (nl) 1997-01-06
IT7827067A0 (it) 1978-08-25
NO782713L (no) 1979-02-28
AU3921478A (en) 1980-02-28
ES472838A1 (es) 1979-03-16
NL960027I2 (nl) 1997-07-01
AU3930478A (en) 1980-03-06
PT68474A (de) 1978-09-01
HU182449B (en) 1984-01-30

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