JPH10287651A5 - - Google Patents

Info

Publication number
JPH10287651A5
JPH10287651A5 JP1998107161A JP10716198A JPH10287651A5 JP H10287651 A5 JPH10287651 A5 JP H10287651A5 JP 1998107161 A JP1998107161 A JP 1998107161A JP 10716198 A JP10716198 A JP 10716198A JP H10287651 A5 JPH10287651 A5 JP H10287651A5
Authority
JP
Japan
Prior art keywords
alkyl
fluorine
cooh
coor11
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998107161A
Other languages
English (en)
Japanese (ja)
Other versions
JPH10287651A (ja
JP4234805B2 (ja
Filing date
Publication date
Priority claimed from DE1998102530 external-priority patent/DE19802530A1/de
Application filed filed Critical
Publication of JPH10287651A publication Critical patent/JPH10287651A/ja
Publication of JPH10287651A5 publication Critical patent/JPH10287651A5/ja
Application granted granted Critical
Publication of JP4234805B2 publication Critical patent/JP4234805B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP10716198A 1997-04-04 1998-04-03 プロパノールアミン誘導体、それらの製法、それらを含有する薬剤およびそれらの使用 Expired - Fee Related JP4234805B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19713865 1997-04-04
DE19713865:9 1998-01-26
DE19802530:0 1998-01-26
DE1998102530 DE19802530A1 (de) 1998-01-26 1998-01-26 Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung

Publications (3)

Publication Number Publication Date
JPH10287651A JPH10287651A (ja) 1998-10-27
JPH10287651A5 true JPH10287651A5 (enExample) 2005-09-08
JP4234805B2 JP4234805B2 (ja) 2009-03-04

Family

ID=26035472

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10716198A Expired - Fee Related JP4234805B2 (ja) 1997-04-04 1998-04-03 プロパノールアミン誘導体、それらの製法、それらを含有する薬剤およびそれらの使用

Country Status (23)

Country Link
US (1) US5874451A (enExample)
EP (1) EP0869121B1 (enExample)
JP (1) JP4234805B2 (enExample)
KR (1) KR19980081055A (enExample)
CN (1) CN1185217C (enExample)
AR (1) AR011210A1 (enExample)
AT (1) ATE268758T1 (enExample)
AU (1) AU730228B2 (enExample)
BR (1) BR9801150A (enExample)
CA (1) CA2233925A1 (enExample)
CZ (1) CZ293758B6 (enExample)
DE (1) DE59811528D1 (enExample)
DK (1) DK0869121T3 (enExample)
ES (1) ES2223091T3 (enExample)
HU (1) HUP9800781A3 (enExample)
ID (1) ID20137A (enExample)
IL (1) IL123927A (enExample)
MY (1) MY114944A (enExample)
NZ (1) NZ330110A (enExample)
PL (1) PL325699A1 (enExample)
PT (1) PT869121E (enExample)
RU (1) RU2198876C2 (enExample)
TR (1) TR199800608A2 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19845402B4 (de) 1998-10-02 2005-04-07 Aventis Pharma Deutschland Gmbh Mit Heterocyclen substituierte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
ATE274510T1 (de) 1998-06-19 2004-09-15 Chiron Corp Glycogen synthase kinase 3 inhibitoren
US7045519B2 (en) 1998-06-19 2006-05-16 Chiron Corporation Inhibitors of glycogen synthase kinase 3
DE19845403B4 (de) * 1998-10-02 2005-02-10 Aventis Pharma Deutschland Gmbh Mit Gallensäuren verknüpfte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
DE19845405C2 (de) 1998-10-02 2000-07-13 Aventis Pharma Gmbh Arylsubstituierte Propanolaminderivate und deren Verwendung
DE19845406C2 (de) * 1998-10-02 2001-10-18 Aventis Pharma Gmbh Substituierte 1,3-Diaryl-2-pyridin-2-yl-3-(pyridin-2-ylamino)- propanolderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
HRP20030501A2 (en) * 2000-12-21 2005-04-30 Aventis Pharma Deutschland Gmbh Diphenyl azetidinone derivatives, method for the production thereof, medicaments containing these compounds, and their use
EP1420826A2 (de) * 2001-08-22 2004-05-26 Aventis Pharma Deutschland GmbH Kombinationspräparate von arylsubstituierten propanolaminderivaten mit weiteren wirkstoffen und deren verwendung
JP4691988B2 (ja) 2002-10-03 2011-06-01 小野薬品工業株式会社 Lpa受容体拮抗剤
GB0307918D0 (en) 2003-04-05 2003-05-14 Astrazeneca Ab Therapeutic use
WO2005058790A1 (ja) * 2003-12-19 2005-06-30 Ono Pharmaceutical Co., Ltd. リゾホスファチジン酸受容体拮抗作用を有する化合物およびその用途
CN1869002A (zh) * 2005-05-27 2006-11-29 中国科学院上海药物研究所 一类非甾体雄激素受体调节剂、其制备方法和用途
WO2008058341A1 (en) * 2006-11-15 2008-05-22 Cytopia Research Pty Ltd Inhibitors of kinase activity
US20110294767A1 (en) 2010-05-26 2011-12-01 Satiogen Pharmaceuticals, Inc. Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions
AU2012328453B2 (en) 2011-10-28 2017-05-04 Shire Human Genetic Therapies, Inc. Bile acid recycling inhibitors for treatment of hypercholemia and cholestatic liver disease
ES2633766T3 (es) 2011-10-28 2017-09-25 Lumena Pharmaceuticals Llc Inhibidores de reciclaje de ácido biliar para el tratamiento de enfermedades de hígado colestático pediátrico
KR20230152818A (ko) 2013-03-15 2023-11-03 샤이어 휴먼 지네틱 테라피즈 인크. 원발성 담관염 및 염증성 장 질환 치료용 담즙산 재순환 억제제
JP2016514678A (ja) 2013-03-15 2016-05-23 ルメナ ファーマシューティカルズ エルエルシー バレット食道と胃食道逆流性疾患を処置するための胆汁酸再利用阻害剤
CN105553262B (zh) * 2015-08-24 2018-02-16 苏州瑞铬优电子科技有限公司 一种提高dc/dc升压变换器转换效率的方法
ES2982943T3 (es) 2019-02-12 2024-10-21 Mirum Pharmaceuticals Inc Métodos para aumentar el crecimiento en sujetos pediátricos con hepatopatía colestásica

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI892341L (fi) * 1988-06-10 1989-12-11 Hoffmann La Roche Propanolaminderivat.
US5250524A (en) * 1990-12-06 1993-10-05 Hoechst Aktiengesellschaft Bile acid derivatives, process for their preparation and use of these compounds as pharmaceuticals
DE4040026A1 (de) * 1990-12-14 1992-06-17 Bayer Ag Substituierte pyridyl-dihydroxy-heptensaeure und deren salze
GB9203347D0 (en) * 1992-02-17 1992-04-01 Wellcome Found Hypolipidaemic compounds
DK0557879T3 (da) * 1992-02-22 1997-06-16 Hoechst Ag 4-amino-2-ureido-pyrimidin-5-carboxylsyreamider, fremgangsmåde til deres fremstilling, lægemidler med indhold af disse forbindelser og deres anvendelse

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