DK0869121T3 - Hypolipidæmiske propanolaminderivater - Google Patents
Hypolipidæmiske propanolaminderivaterInfo
- Publication number
- DK0869121T3 DK0869121T3 DK98105256T DK98105256T DK0869121T3 DK 0869121 T3 DK0869121 T3 DK 0869121T3 DK 98105256 T DK98105256 T DK 98105256T DK 98105256 T DK98105256 T DK 98105256T DK 0869121 T3 DK0869121 T3 DK 0869121T3
- Authority
- DK
- Denmark
- Prior art keywords
- hypolipidemic
- propanolamine derivatives
- propanolamine
- derivatives
- hypolipidemic propanolamine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19713865 | 1997-04-04 | ||
DE1998102530 DE19802530A1 (de) | 1998-01-26 | 1998-01-26 | Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0869121T3 true DK0869121T3 (da) | 2004-09-20 |
Family
ID=26035472
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98105256T DK0869121T3 (da) | 1997-04-04 | 1998-03-24 | Hypolipidæmiske propanolaminderivater |
Country Status (24)
Country | Link |
---|---|
US (1) | US5874451A (da) |
EP (1) | EP0869121B1 (da) |
JP (1) | JP4234805B2 (da) |
KR (1) | KR19980081055A (da) |
CN (1) | CN1185217C (da) |
AR (1) | AR011210A1 (da) |
AT (1) | ATE268758T1 (da) |
AU (1) | AU730228B2 (da) |
BR (1) | BR9801150A (da) |
CA (1) | CA2233925A1 (da) |
CZ (1) | CZ293758B6 (da) |
DE (1) | DE59811528D1 (da) |
DK (1) | DK0869121T3 (da) |
ES (1) | ES2223091T3 (da) |
HK (1) | HK1015789A1 (da) |
HU (1) | HUP9800781A3 (da) |
ID (1) | ID20137A (da) |
IL (1) | IL123927A (da) |
MY (1) | MY114944A (da) |
NZ (1) | NZ330110A (da) |
PL (1) | PL325699A1 (da) |
PT (1) | PT869121E (da) |
RU (1) | RU2198876C2 (da) |
TR (1) | TR199800608A2 (da) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19845402B4 (de) | 1998-10-02 | 2005-04-07 | Aventis Pharma Deutschland Gmbh | Mit Heterocyclen substituierte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
CN1312807A (zh) | 1998-06-19 | 2001-09-12 | 希龙公司 | 糖元合成酶激酶3的抑制剂 |
US7045519B2 (en) * | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
DE19845403B4 (de) * | 1998-10-02 | 2005-02-10 | Aventis Pharma Deutschland Gmbh | Mit Gallensäuren verknüpfte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
DE19845405C2 (de) | 1998-10-02 | 2000-07-13 | Aventis Pharma Gmbh | Arylsubstituierte Propanolaminderivate und deren Verwendung |
DE19845406C2 (de) * | 1998-10-02 | 2001-10-18 | Aventis Pharma Gmbh | Substituierte 1,3-Diaryl-2-pyridin-2-yl-3-(pyridin-2-ylamino)- propanolderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
AU2002231688A1 (en) | 2000-12-21 | 2002-07-01 | Sanofi-Aventis Deutschland Gmbh | Diphenyl azetidinone derivatives, method for the production thereof, medicaments containing these compounds, and their use |
PL366855A1 (en) * | 2001-08-22 | 2005-02-07 | Aventis Pharma Deutschland Gmbh | Combination preparations of aryl substituted propanolamine derivatives with other active ingredients and the use thereof |
WO2004031118A1 (ja) | 2002-10-03 | 2004-04-15 | Ono Pharmaceutical Co., Ltd. | Lpa受容体拮抗剤 |
GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
ATE528276T1 (de) | 2003-12-19 | 2011-10-15 | Ono Pharmaceutical Co | Lysophosphatidylsäurerezeptor-antagonistische verbindungen und ihre anwendungen |
CN1869002A (zh) * | 2005-05-27 | 2006-11-29 | 中国科学院上海药物研究所 | 一类非甾体雄激素受体调节剂、其制备方法和用途 |
WO2008058341A1 (en) * | 2006-11-15 | 2008-05-22 | Cytopia Research Pty Ltd | Inhibitors of kinase activity |
ES2552657T3 (es) | 2010-05-26 | 2015-12-01 | Satiogen Pharmaceuticals, Inc. | Inhibidores del reciclado de ácidos biliares y saciógenos para el tratamiento de diabetes, obesidad, y afecciones gastrointestinales inflamatorias |
PL2771003T3 (pl) | 2011-10-28 | 2017-10-31 | Lumena Pharmaceuticals Llc | Inhibitory ponownego wykorzystania kwasów żółciowych do leczenia pediatrycznych cholestatycznych chorób wątroby |
US20140323412A1 (en) | 2011-10-28 | 2014-10-30 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of hypercholemia and cholestatic liver disease |
BR112015023697A2 (pt) | 2013-03-15 | 2017-07-18 | Lumena Pharmaceuticals Inc | inibidores de ácidos biliares de reciclagem para tratamento de esôfago de barrett e doença do refluxo gastroesofágico |
KR20230152818A (ko) | 2013-03-15 | 2023-11-03 | 샤이어 휴먼 지네틱 테라피즈 인크. | 원발성 담관염 및 염증성 장 질환 치료용 담즙산 재순환 억제제 |
CN105553262B (zh) * | 2015-08-24 | 2018-02-16 | 苏州瑞铬优电子科技有限公司 | 一种提高dc/dc升压变换器转换效率的方法 |
BR112021015799A2 (pt) | 2019-02-12 | 2022-01-18 | Mirum Pharmaceuticals Inc | Métodos para aumentar o crescimento em pacientes pediátricos com doença colestática do fígado |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI892341A (fi) * | 1988-06-10 | 1989-12-11 | Hoffmann La Roche | Propanolaminderivat. |
NZ240846A (en) * | 1990-12-06 | 1994-04-27 | Hoechst Ag | Dimeric bile acid derivatives; preparatory processes and pharmaceutical compositions |
GB9203347D0 (en) * | 1992-02-17 | 1992-04-01 | Wellcome Found | Hypolipidaemic compounds |
DE59305012D1 (de) * | 1992-02-22 | 1997-02-20 | Hoechst Ag | 4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
-
1998
- 1998-03-24 ES ES98105256T patent/ES2223091T3/es not_active Expired - Lifetime
- 1998-03-24 EP EP98105256A patent/EP0869121B1/de not_active Expired - Lifetime
- 1998-03-24 PT PT98105256T patent/PT869121E/pt unknown
- 1998-03-24 AT AT98105256T patent/ATE268758T1/de not_active IP Right Cessation
- 1998-03-24 DE DE59811528T patent/DE59811528D1/de not_active Expired - Lifetime
- 1998-03-24 DK DK98105256T patent/DK0869121T3/da active
- 1998-04-02 TR TR1998/00608A patent/TR199800608A2/xx unknown
- 1998-04-02 US US09/053,513 patent/US5874451A/en not_active Expired - Lifetime
- 1998-04-02 AR ARP980101512A patent/AR011210A1/es unknown
- 1998-04-02 ID IDP980494A patent/ID20137A/id unknown
- 1998-04-02 NZ NZ330110A patent/NZ330110A/xx unknown
- 1998-04-02 IL IL12392798A patent/IL123927A/xx active IP Right Grant
- 1998-04-03 HU HU9800781A patent/HUP9800781A3/hu unknown
- 1998-04-03 RU RU98106112/04A patent/RU2198876C2/ru not_active IP Right Cessation
- 1998-04-03 CN CNB981082521A patent/CN1185217C/zh not_active Expired - Fee Related
- 1998-04-03 JP JP10716198A patent/JP4234805B2/ja not_active Expired - Fee Related
- 1998-04-03 CZ CZ19981025A patent/CZ293758B6/cs not_active IP Right Cessation
- 1998-04-03 CA CA002233925A patent/CA2233925A1/en not_active Abandoned
- 1998-04-03 MY MYPI98001488A patent/MY114944A/en unknown
- 1998-04-03 AU AU60624/98A patent/AU730228B2/en not_active Ceased
- 1998-04-03 KR KR1019980011750A patent/KR19980081055A/ko active IP Right Grant
- 1998-04-03 PL PL98325699A patent/PL325699A1/xx not_active Application Discontinuation
- 1998-04-06 BR BR9801150A patent/BR9801150A/pt not_active IP Right Cessation
-
1999
- 1999-03-12 HK HK99101018A patent/HK1015789A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2233925A1 (en) | 1998-10-04 |
PL325699A1 (en) | 1998-10-12 |
HU9800781D0 (en) | 1998-05-28 |
CZ293758B6 (cs) | 2004-07-14 |
MY114944A (en) | 2003-02-28 |
CN1185217C (zh) | 2005-01-19 |
HK1015789A1 (en) | 1999-10-22 |
CN1199731A (zh) | 1998-11-25 |
IL123927A (en) | 2001-01-28 |
NZ330110A (en) | 1999-03-29 |
AR011210A1 (es) | 2000-08-02 |
PT869121E (pt) | 2004-10-29 |
RU2198876C2 (ru) | 2003-02-20 |
ES2223091T3 (es) | 2005-02-16 |
EP0869121A1 (de) | 1998-10-07 |
KR19980081055A (ko) | 1998-11-25 |
DE59811528D1 (de) | 2004-07-15 |
TR199800608A3 (tr) | 1998-10-21 |
AU730228B2 (en) | 2001-03-01 |
HUP9800781A2 (hu) | 1999-06-28 |
ID20137A (id) | 1998-10-08 |
CZ102598A3 (cs) | 1998-10-14 |
US5874451A (en) | 1999-02-23 |
HUP9800781A3 (en) | 1999-07-28 |
TR199800608A2 (en) | 1998-10-21 |
EP0869121B1 (de) | 2004-06-09 |
JP4234805B2 (ja) | 2009-03-04 |
ATE268758T1 (de) | 2004-06-15 |
AU6062498A (en) | 1998-10-08 |
JPH10287651A (ja) | 1998-10-27 |
BR9801150A (pt) | 2000-03-21 |
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