JPH0613611B2 - 水性媒体と抗体又は酵素を固定するための核―外皮構造を有するポリマー粒子とからなるポリマーラテックス - Google Patents
水性媒体と抗体又は酵素を固定するための核―外皮構造を有するポリマー粒子とからなるポリマーラテックスInfo
- Publication number
- JPH0613611B2 JPH0613611B2 JP57070541A JP7054182A JPH0613611B2 JP H0613611 B2 JPH0613611 B2 JP H0613611B2 JP 57070541 A JP57070541 A JP 57070541A JP 7054182 A JP7054182 A JP 7054182A JP H0613611 B2 JPH0613611 B2 JP H0613611B2
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- core
- polymer latex
- monomer
- latex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F291/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds according to more than one of the groups C08F251/00 - C08F289/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S525/00—Synthetic resins or natural rubbers -- part of the class 520 series
- Y10S525/902—Core-shell
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Pathology (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Polymerisation Methods In General (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Peptides Or Proteins (AREA)
- Graft Or Block Polymers (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3116995.3 | 1981-04-29 | ||
DE31169953 | 1981-04-29 | ||
DE19813116995 DE3116995A1 (de) | 1981-04-29 | 1981-04-29 | Latex zur immobilisierung von biologisch wirksamen substanzen |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2263967A Division JPH0723893B2 (ja) | 1981-04-29 | 1990-10-03 | 抗体の固定法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS585302A JPS585302A (ja) | 1983-01-12 |
JPH0613611B2 true JPH0613611B2 (ja) | 1994-02-23 |
Family
ID=6131085
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP57070541A Expired - Lifetime JPH0613611B2 (ja) | 1981-04-29 | 1982-04-28 | 水性媒体と抗体又は酵素を固定するための核―外皮構造を有するポリマー粒子とからなるポリマーラテックス |
JP2263967A Expired - Lifetime JPH0723893B2 (ja) | 1981-04-29 | 1990-10-03 | 抗体の固定法 |
JP4125759A Expired - Lifetime JP2536995B2 (ja) | 1981-04-29 | 1992-05-19 | 酵素固定法 |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2263967A Expired - Lifetime JPH0723893B2 (ja) | 1981-04-29 | 1990-10-03 | 抗体の固定法 |
JP4125759A Expired - Lifetime JP2536995B2 (ja) | 1981-04-29 | 1992-05-19 | 酵素固定法 |
Country Status (7)
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3145082A1 (de) * | 1981-11-13 | 1983-05-19 | Behringwerke Ag, 3550 Marburg | "ein latex, biologisch aktive latexkonjugate und verfahren zu ihrer herstellung" |
US4828996A (en) * | 1983-01-04 | 1989-05-09 | Rolf Siegel | Materials and method for immobilizing biologically active substances |
EP0164889A3 (en) * | 1984-05-07 | 1986-12-17 | HSC Research Development Corporation | Surface-treated polymeric substrates |
US5225279A (en) * | 1985-04-30 | 1993-07-06 | Rohm And Haas Company | Solvent core encapsulant composition |
US4677003A (en) * | 1985-04-30 | 1987-06-30 | Rohm And Haas Company | Microsuspension process for preparing solvent core sequential polymer dispersion |
DE3530312A1 (de) * | 1985-08-24 | 1987-02-26 | Guenther Dr Sawatzki | Traeger fuer die photometrische immunspezifische bestimmung von antigenen oder antikoerpern, verfahren zu ihrer herstellung und verwendung |
DE3621719A1 (de) * | 1986-06-28 | 1988-01-14 | Roehm Gmbh | Verfahren zur ausloesung der bildung von antikoerpern |
DE3622993A1 (de) * | 1986-07-09 | 1988-01-21 | Behringwerke Ag | Dispersionspolymere, biologisch aktive dispersionspolymere, verfahren zu ihrer herstellung und verwendung als diagnostisches mittel |
EP0280556B1 (en) * | 1987-02-27 | 1994-08-10 | EASTMAN KODAK COMPANY (a New Jersey corporation) | Water-insoluble particle and immunoreactive reagent, analytical elements and methods of use |
US4997772A (en) * | 1987-09-18 | 1991-03-05 | Eastman Kodak Company | Water-insoluble particle and immunoreactive reagent, analytical elements and methods of use |
JPH01104621A (ja) * | 1987-09-18 | 1989-04-21 | Eastman Kodak Co | ポリマーラテックス組成物の製造方法 |
US4810763A (en) * | 1987-12-23 | 1989-03-07 | Avery International Corporation | Suspension polymerization in an organic medium |
DE3811042A1 (de) * | 1988-03-31 | 1989-10-19 | Merck Patent Gmbh | Ionenaustauscher |
US5258454A (en) * | 1988-09-01 | 1993-11-02 | Riso National Laboratory | Peptide synthesis method and solid support for use in the method |
JP2816414B2 (ja) * | 1989-01-20 | 1998-10-27 | ディアグノスティカ スタゴ | サブミクロン粒子,調整及び免疫反応診断学における用途 |
US4990279A (en) * | 1989-04-21 | 1991-02-05 | Hercules Incorporated | Electrorheological fluids |
DE69017748T2 (de) * | 1989-05-10 | 1995-07-06 | Nippon Zeon Co | Vinylchloridharz für Sicherheitsglas und Verfahren zur Herstellung des Harzes. |
US6120805A (en) * | 1990-04-06 | 2000-09-19 | Rhone-Poulenc Rorer Sa | Microspheres, process for their preparation and their use |
US5216130A (en) * | 1990-05-17 | 1993-06-01 | Albany Medical College | Complex for in-vivo target localization |
US5200315A (en) * | 1990-07-25 | 1993-04-06 | Eastman Kodak Company | Particulate biologically active reagent containing polyoxyalkylene side chains, analytical element and methods for use of the reagent |
US5086143A (en) * | 1990-07-25 | 1992-02-04 | Eastman Kodak Company | Copolymers containing polyoxyalkylene side chains |
DE4026992A1 (de) * | 1990-08-25 | 1992-02-27 | Roehm Gmbh | Verfahren zur herstellung von traegersystemen fuer biologisch aktive materialien |
US5200471A (en) * | 1990-11-05 | 1993-04-06 | Minnesota Mining And Manufacturing Company | Biomolecules covalently immobilized with a high bound specific biological activity and method of preparing same |
US5308749A (en) * | 1991-01-25 | 1994-05-03 | Eastman Kodak Company | Method of preparing biologically active reagents from succinimide-containing polymers, analytical element and methods of use |
US5200462A (en) * | 1991-01-25 | 1993-04-06 | Eastman Kodak Company | Succinimide containing polymers and lattices prepared from same |
US5573934A (en) * | 1992-04-20 | 1996-11-12 | Board Of Regents, The University Of Texas System | Gels for encapsulation of biological materials |
US5385959A (en) * | 1992-04-29 | 1995-01-31 | Lever Brothers Company, Division Of Conopco, Inc. | Capsule which comprises a component subject to degradation and a composite polymer |
DK168670B1 (da) | 1993-03-09 | 1994-05-16 | Niro Separation As | Apparat til fordeling af fibre |
US5461125A (en) * | 1993-04-30 | 1995-10-24 | Minnesota Mining And Manufacturing Company | Waterborne core-shell latex polymers |
JP3583429B2 (ja) * | 1993-07-16 | 2004-11-04 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | 疎水クロマトグラフィーのための分離剤 |
DE4333674A1 (de) * | 1993-10-02 | 1995-04-06 | Merck Patent Gmbh | Nukleotidhaltiges Sorbens für die Affinitätschromatographie |
DE4333821A1 (de) * | 1993-10-04 | 1995-04-06 | Merck Patent Gmbh | Ionenaustauscher |
DE4334353A1 (de) * | 1993-10-08 | 1995-04-13 | Merck Patent Gmbh | Verfahren und Träger für die Gelpermeationschromatographie |
US5432210A (en) * | 1993-11-22 | 1995-07-11 | Rohm And Haas Company | Polymer particles and method for preparing by polymerization of encapsulated monomers |
US5776651A (en) * | 1996-01-31 | 1998-07-07 | Minnesota Mining & Manufacturing Company | Laminable proofing elements |
EP0907889B1 (en) | 1996-04-25 | 2007-07-04 | BioArray Solutions Ltd. | Light-controlled electrokinetic assembly of particles near surfaces |
US6417249B1 (en) | 1997-10-31 | 2002-07-09 | Hewlett-Packard Company | Ink-jet printing ink compositions having superior smear-fastness |
US5990202A (en) * | 1997-10-31 | 1999-11-23 | Hewlett-Packard Company | Dual encapsulation technique for preparing ink-jets inks |
US6057384A (en) * | 1997-10-31 | 2000-05-02 | Hewlett-Packard Company | Latex polymer blends for improving the permanence of ink-jet inks |
AU5154000A (en) * | 1999-05-19 | 2000-12-05 | Brigham Young University | Stabilization and acoustic activation of polymeric micelles for drug delivery |
US9709559B2 (en) | 2000-06-21 | 2017-07-18 | Bioarray Solutions, Ltd. | Multianalyte molecular analysis using application-specific random particle arrays |
ES2259666T3 (es) | 2000-06-21 | 2006-10-16 | Bioarray Solutions Ltd | Analisis molecular de multiples analitos usando series de particulas aleatorias con especificidad de aplicacion. |
CA2420552A1 (en) * | 2000-10-02 | 2002-04-11 | Kimberly-Clark Worldwide, Inc. | Nanoparticle based inks and methods of making the same |
US7262063B2 (en) * | 2001-06-21 | 2007-08-28 | Bio Array Solutions, Ltd. | Directed assembly of functional heterostructures |
EP2722395B1 (en) | 2001-10-15 | 2018-12-19 | Bioarray Solutions Ltd | Multiplexed analysis of polymorphic loci by concurrent interrogation and enzyme-mediated detection |
US6792019B2 (en) * | 2002-02-28 | 2004-09-14 | Texas Instruments Incorporated | Driver with tail currents in discrete subranges |
US7526114B2 (en) | 2002-11-15 | 2009-04-28 | Bioarray Solutions Ltd. | Analysis, secure access to, and transmission of array images |
US6964747B2 (en) * | 2003-01-21 | 2005-11-15 | Bioarray Solutions, Ltd. | Production of dyed polymer microparticles |
US7255895B2 (en) * | 2003-01-21 | 2007-08-14 | Bioarray Solutions, Ltd. | Method for controlling solute loading of polymer microparticles |
JP3954522B2 (ja) * | 2003-04-18 | 2007-08-08 | 日清紡績株式会社 | 生物学的活性物質を固定化した素子 |
WO2005029705A2 (en) | 2003-09-18 | 2005-03-31 | Bioarray Solutions, Ltd. | Number coding for identification of subtypes of coded types of solid phase carriers |
WO2005031305A2 (en) | 2003-09-22 | 2005-04-07 | Bioarray Solutions, Ltd. | Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules |
JP2007521017A (ja) | 2003-10-28 | 2007-08-02 | バイオアレイ ソリューションズ リミテッド | 固定化捕捉プローブを用いる遺伝子発現分析法の最適化 |
EP1694859B1 (en) | 2003-10-29 | 2015-01-07 | Bioarray Solutions Ltd | Multiplexed nucleic acid analysis by fragmentation of double-stranded dna |
ATE374044T1 (de) * | 2004-04-05 | 2007-10-15 | Basf Ag | Wirkstoffhaltige polymerteilchen |
US7848889B2 (en) | 2004-08-02 | 2010-12-07 | Bioarray Solutions, Ltd. | Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification |
CA2576272C (en) * | 2004-09-02 | 2013-06-25 | I-Stat Corporation | Blood urea nitrogen (bun) sensor |
EP1802349A1 (en) * | 2004-10-13 | 2007-07-04 | Ilypsa, Inc. | Pharmaceutical compositions comprising a toxin-binding oligosaccharide and a polymeric particle |
US20060078534A1 (en) * | 2004-10-13 | 2006-04-13 | Dominique Charmot | Toxin binding compositions |
US8486629B2 (en) | 2005-06-01 | 2013-07-16 | Bioarray Solutions, Ltd. | Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation |
JP5200425B2 (ja) * | 2006-06-23 | 2013-06-05 | 住友化学株式会社 | 農薬活性微生物製剤 |
US9910040B2 (en) | 2012-07-09 | 2018-03-06 | Sevident, Inc. | Molecular nets comprising capture agents and linking agents |
US9733242B2 (en) | 2012-10-07 | 2017-08-15 | Sevident, Inc. | Devices for capturing analyte |
EP2712877B1 (en) * | 2012-09-28 | 2015-04-01 | Rohm and Haas Company | Curable formaldehyde free compositions as binders having solvent resistance |
CN110068677A (zh) * | 2013-03-14 | 2019-07-30 | 赛维德恩特有限公司 | 固相上的分子网 |
JP7091128B2 (ja) * | 2018-04-27 | 2022-06-27 | キヤノン株式会社 | 粒子、及びその製造方法 |
GB201907468D0 (en) * | 2019-05-28 | 2019-07-10 | Univ Loughborough | Dispersion |
CN113416267B (zh) * | 2021-07-28 | 2022-09-20 | 万华化学(四川)有限公司 | 一种改善工艺污水可生化性的abs接枝胶乳的凝聚方法 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2046898B2 (de) * | 1969-09-26 | 1977-09-22 | The Japanese Geon Co, Ltd, Tokio | Verfahren zur herstellung von propfmischpolymerisaten und deren verwendung in polyvinylchlorid enthaltenden formkoerpern |
US3661994A (en) * | 1969-11-14 | 1972-05-09 | Stauffer Chemical Co | Graft polymers of rubber for reinforcing plastics |
US3787522A (en) * | 1972-11-01 | 1974-01-22 | Ford Motor Co | Acrylate polymer particles comprising a core,an outer shell,and an intermediate layer |
US3856883A (en) * | 1973-05-29 | 1974-12-24 | Ford Motor Co | Graded rubber particles having hydroxy functionality and a polymeric crosslinking agent |
US4138383A (en) * | 1975-11-24 | 1979-02-06 | California Institute Of Technology | Preparation of small bio-compatible microspheres |
US4107120A (en) * | 1976-06-17 | 1978-08-15 | Rohm And Haas Company | Heteropolymer acrylic latices and textiles treated therewith |
US4210723A (en) * | 1976-07-23 | 1980-07-01 | The Dow Chemical Company | Method of coupling a protein to an epoxylated latex |
US4140662A (en) * | 1977-03-25 | 1979-02-20 | Ortho Diagnostics, Inc. | Attachment of proteins to inert particles |
CH628738A5 (de) * | 1977-08-03 | 1982-03-15 | Hoffmann La Roche | Immunologisches diagnose-reagenz. |
FR2399448A1 (fr) * | 1977-08-03 | 1979-03-02 | Rhone Poulenc Ind | Latex de polymeres vinyliques stables aux electrolytes |
GB2005275B (en) * | 1977-09-19 | 1982-03-10 | Hoffmann La Roche | Immunological reagent |
EP0001223A3 (en) * | 1977-09-19 | 1979-12-12 | F.Hoffmann-La Roche & Co. Aktiengesellschaft | Latex coated with a polyhydroxy compound, process for the preparation of this latex, immunological reagent containing this latex, process for the preparation of this reagent, application of this reagent, testing procedure utilising this reagent and reagent kit containing this reagent |
CA1101330A (en) * | 1977-09-19 | 1981-05-19 | Ernst A. Fischer | Immunological material bonded to carboxylated latex polymer and process for making it |
GB2041940B (en) * | 1979-02-17 | 1982-12-22 | Dow Chemical Co | Method of coupling a protein to an epoxylated latex and the products formed therefrom |
JPS55110118A (en) * | 1979-02-20 | 1980-08-25 | Dow Chemical Co | Method of combining epoxylated latex with protein and product formed therefrom |
DE2907794A1 (de) * | 1979-02-28 | 1980-09-11 | Dow Chemical Co | Protein-latex-konjugat und verfahren zu seiner herstellung |
JPS5655414A (en) * | 1979-10-11 | 1981-05-16 | Japan Synthetic Rubber Co Ltd | Polymer particle |
-
1981
- 1981-04-29 DE DE19813116995 patent/DE3116995A1/de active Granted
-
1982
- 1982-02-04 AT AT82100784T patent/ATE19524T1/de not_active IP Right Cessation
- 1982-02-04 EP EP82100784A patent/EP0065069B1/de not_active Expired
- 1982-03-30 DK DK144382A patent/DK163668C/da not_active IP Right Cessation
- 1982-04-28 JP JP57070541A patent/JPH0613611B2/ja not_active Expired - Lifetime
- 1982-04-29 MX MX192489A patent/MX160019A/es unknown
-
1986
- 1986-11-07 US US06/930,023 patent/US4710525A/en not_active Expired - Fee Related
-
1987
- 1987-07-20 US US07/075,416 patent/US4829101A/en not_active Expired - Lifetime
-
1990
- 1990-10-03 JP JP2263967A patent/JPH0723893B2/ja not_active Expired - Lifetime
-
1992
- 1992-05-19 JP JP4125759A patent/JP2536995B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE3116995C2 (US06171609-20010109-C00004.png) | 1990-08-09 |
EP0065069B1 (de) | 1986-04-30 |
EP0065069A2 (de) | 1982-11-24 |
US4829101A (en) | 1989-05-09 |
JP2536995B2 (ja) | 1996-09-25 |
JPH03210476A (ja) | 1991-09-13 |
JPS585302A (ja) | 1983-01-12 |
JPH05346430A (ja) | 1993-12-27 |
JPH0723893B2 (ja) | 1995-03-15 |
MX160019A (es) | 1989-11-07 |
ATE19524T1 (de) | 1986-05-15 |
DK163668C (da) | 1992-08-17 |
EP0065069A3 (en) | 1983-04-27 |
DK144382A (da) | 1982-10-30 |
US4710525A (en) | 1987-12-01 |
DE3116995A1 (de) | 1982-11-25 |
DK163668B (da) | 1992-03-23 |
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