JPH05103838A - タンパク質又はポリペプチドと疎水性生物分解性ポリマーとの相互作用を包含する薬物投与システム - Google Patents
タンパク質又はポリペプチドと疎水性生物分解性ポリマーとの相互作用を包含する薬物投与システムInfo
- Publication number
- JPH05103838A JPH05103838A JP3179588A JP17958891A JPH05103838A JP H05103838 A JPH05103838 A JP H05103838A JP 3179588 A JP3179588 A JP 3179588A JP 17958891 A JP17958891 A JP 17958891A JP H05103838 A JPH05103838 A JP H05103838A
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- protein
- polymer
- hormone
- drug delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
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| US55442790A | 1990-07-19 | 1990-07-19 | |
| US554427 | 1990-07-19 |
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| JPH05103838A true JPH05103838A (ja) | 1993-04-27 |
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| JP3179588A Pending JPH05103838A (ja) | 1990-07-19 | 1991-07-19 | タンパク質又はポリペプチドと疎水性生物分解性ポリマーとの相互作用を包含する薬物投与システム |
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| JP (1) | JPH05103838A (enExample) |
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| EP0354714A3 (en) | 1988-08-12 | 1991-04-10 | Hadassah Medical Organization | Pharmaceutical compositions containing polyaromatic compounds |
| US5008116A (en) * | 1988-11-14 | 1991-04-16 | Frederick Cahn | Immunostimulatory microsphere |
| US5019400A (en) * | 1989-05-01 | 1991-05-28 | Enzytech, Inc. | Very low temperature casting of controlled release microspheres |
| EP0499619B1 (en) * | 1989-11-06 | 1996-02-07 | Alkermes Controlled Therapeutics, Inc. | Method for producing protein microspheres |
-
1991
- 1991-07-11 CA CA002046830A patent/CA2046830C/en not_active Expired - Fee Related
- 1991-07-12 NZ NZ238951A patent/NZ238951A/en not_active IP Right Cessation
- 1991-07-15 NO NO912769A patent/NO304411B1/no unknown
- 1991-07-16 AU AU80466/91A patent/AU656897B2/en not_active Ceased
- 1991-07-17 ZA ZA915584A patent/ZA915584B/xx unknown
- 1991-07-17 FI FI913455A patent/FI104954B/fi not_active IP Right Cessation
- 1991-07-17 MX MX9100249A patent/MX9100249A/es not_active IP Right Cessation
- 1991-07-19 PT PT98397A patent/PT98397B/pt active IP Right Revival
- 1991-07-19 CS CS912248A patent/CS224891A3/cs unknown
- 1991-07-19 ES ES91112118T patent/ES2138584T3/es not_active Expired - Lifetime
- 1991-07-19 AT AT91112118T patent/ATE185269T1/de not_active IP Right Cessation
- 1991-07-19 DK DK91112118T patent/DK0467389T3/da active
- 1991-07-19 DE DE69131677T patent/DE69131677T2/de not_active Expired - Fee Related
- 1991-07-19 EP EP91112118A patent/EP0467389B1/en not_active Expired - Lifetime
- 1991-07-19 JP JP3179588A patent/JPH05103838A/ja active Pending
-
1995
- 1995-06-07 US US08/481,155 patent/US6306406B1/en not_active Expired - Fee Related
-
1999
- 1999-12-07 GR GR990403145T patent/GR3032056T3/el unknown
-
2001
- 2001-09-04 US US09/944,369 patent/US20020051808A1/en not_active Abandoned
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001515522A (ja) * | 1998-01-14 | 2001-09-18 | エフラット バイオポリマーズ リミティッド | ポリマーキャリア |
| JP2006509534A (ja) * | 2002-10-31 | 2006-03-23 | トランスファーマ メディカル リミテッド | 乾燥微粒子または凍結乾燥した治療薬の経皮デリバリーシステム |
| US8133505B2 (en) | 2002-10-31 | 2012-03-13 | Transpharma Medical Ltd. | Transdermal delivery system for dried particulate or lyophilized medications |
| JP2007517912A (ja) * | 2004-01-13 | 2007-07-05 | バソジェニックス ファーマシューティカルズ， インコーポレイテッド | 心脈管および腎臓の適応症のための制御放出ｃｇｒｐ送達組成物 |
| JP2007517913A (ja) * | 2004-01-13 | 2007-07-05 | バソジェニックス ファーマシューティカルズ， インコーポレイテッド | カルシトニン遺伝子関連ペプチドを投与することによって急性心筋梗塞を処置するための方法およびカルシトニン遺伝子関連ペプチドを含有する組成物 |
| US7976847B2 (en) | 2004-01-13 | 2011-07-12 | Vasogenix Pharmaceuticals, Inc. | Controlled release CGRP delivery composition for cardiovascular and renal indications |
| JP2013525387A (ja) * | 2010-04-27 | 2013-06-20 | ジーランド ファーマ アクティーゼルスカブ | Ｇｌｐ−１受容体作動薬とガストリンとのペプチド複合体及びその使用 |
| WO2024080308A1 (ja) * | 2022-10-12 | 2024-04-18 | 中外製薬株式会社 | ペプチド、界面活性剤及びポリマーを含む組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| NO304411B1 (no) | 1998-12-14 |
| NO912769L (no) | 1992-01-20 |
| EP0467389A2 (en) | 1992-01-22 |
| FI104954B (fi) | 2000-05-15 |
| MX9100249A (es) | 1992-02-28 |
| EP0467389A3 (enExample) | 1994-02-02 |
| CA2046830C (en) | 1999-12-14 |
| DE69131677T2 (de) | 2000-02-24 |
| PT98397B (pt) | 1999-01-29 |
| EP0467389B1 (en) | 1999-10-06 |
| NO912769D0 (no) | 1991-07-15 |
| FI913455L (fi) | 1992-01-20 |
| CS224891A3 (en) | 1992-03-18 |
| AU8046691A (en) | 1992-01-23 |
| CA2046830A1 (en) | 1992-01-20 |
| FI913455A0 (fi) | 1991-07-17 |
| US6306406B1 (en) | 2001-10-23 |
| GR3032056T3 (en) | 2000-03-31 |
| AU656897B2 (en) | 1995-02-23 |
| DK0467389T3 (da) | 2000-02-28 |
| PT98397A (pt) | 1992-05-29 |
| ZA915584B (en) | 1992-04-29 |
| ES2138584T3 (es) | 2000-01-16 |
| NZ238951A (en) | 1994-12-22 |
| ATE185269T1 (de) | 1999-10-15 |
| DE69131677D1 (de) | 1999-11-11 |
| US20020051808A1 (en) | 2002-05-02 |
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