JPH04500966A - 脈管狭窄の治療におけるγ―インターフェロンの使用 - Google Patents
脈管狭窄の治療におけるγ―インターフェロンの使用Info
- Publication number
- JPH04500966A JPH04500966A JP1510051A JP51005189A JPH04500966A JP H04500966 A JPH04500966 A JP H04500966A JP 1510051 A JP1510051 A JP 1510051A JP 51005189 A JP51005189 A JP 51005189A JP H04500966 A JPH04500966 A JP H04500966A
- Authority
- JP
- Japan
- Prior art keywords
- interferon
- cells
- smooth muscle
- treatment
- expression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/217—IFN-gamma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
Description
Claims (6)
- 1.脈管狭窄の治療用薬剤の調製におけるγ−インターフェロンの使用。
- 2.脈管狭窄が動脈狭窄または閉塞の治療により再狭窄である請求の範囲1記載 のγ−インターフェロンの使用。
- 3.再狭窄が血管形成および/または脈管手術による動脈狭窄である請求の範囲 2記載のγ−インターフェロンの使用。
- 4.γ−インターフェロンを、治療効果を生ずるのに十分な量の前記インターフ ェロンを含有する調剤で、患者に投与することを特徴とする脈管狭窄治療におけ るγ−インターフェロンの使用方法。
- 5.脈管狭窄治療が動脈狭窄または閉塞の治療による再狭窄の治療である請求の 範囲4記載のγ−インターフェロンの使用方法。
- 6.再狭窄治療が脈管手術および/または血管形成による動脈狭窄治療である請 求の範囲5記載のγ−インターフェロンの使用方法。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8803472A SE462364B (sv) | 1988-09-30 | 1988-09-30 | Anvaendning av gamma-interferon foer beredning av ett preparat foer behandling av vaskulaer stenos |
SE8803472-3 | 1988-09-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH04500966A true JPH04500966A (ja) | 1992-02-20 |
JP2895896B2 JP2895896B2 (ja) | 1999-05-24 |
Family
ID=20373494
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1510051A Expired - Lifetime JP2895896B2 (ja) | 1988-09-30 | 1989-09-27 | 脈管狭窄の治療におけるγ―インターフェロンの使用 |
Country Status (18)
Country | Link |
---|---|
US (1) | US5208019A (ja) |
EP (1) | EP0367735B1 (ja) |
JP (1) | JP2895896B2 (ja) |
KR (1) | KR0137017B1 (ja) |
AT (1) | ATE86869T1 (ja) |
AU (1) | AU623181B2 (ja) |
CA (1) | CA1338722C (ja) |
DD (1) | DD288094A5 (ja) |
DE (1) | DE68905438T2 (ja) |
DK (1) | DK174523B1 (ja) |
HU (1) | HU206988B (ja) |
IE (1) | IE63874B1 (ja) |
IL (1) | IL91796A (ja) |
NZ (1) | NZ230816A (ja) |
PH (1) | PH26293A (ja) |
PT (1) | PT91863B (ja) |
SE (1) | SE462364B (ja) |
WO (1) | WO1990003189A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008031179A (ja) * | 1995-11-30 | 2008-02-14 | Berlex Lab Inc | β−インターフェロンを使用して再狭窄を治療する方法 |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5811447A (en) * | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
CA2131550A1 (en) * | 1992-02-05 | 1993-08-19 | Andrew Zalewski | Interferon gene therapy for the treatment of vascular disorders |
US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US5770609A (en) * | 1993-01-28 | 1998-06-23 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6395494B1 (en) | 1993-05-13 | 2002-05-28 | Neorx Corporation | Method to determine TGF-β |
US6306421B1 (en) | 1992-09-25 | 2001-10-23 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5957972A (en) * | 1992-09-29 | 1999-09-28 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Implants possessing a surface of endothelial cells genetically-modified to inhibit intimal thickening |
HU220969B1 (hu) * | 1993-01-07 | 2002-07-29 | Thomas Jefferson University | A C-MYC-re specifikus antiszensz oligonukleotid alkalmazása simaizomsejtek proliferációjának szabályozásában |
US6663881B2 (en) | 1993-01-28 | 2003-12-16 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5595722A (en) * | 1993-01-28 | 1997-01-21 | Neorx Corporation | Method for identifying an agent which increases TGF-beta levels |
US5981568A (en) | 1993-01-28 | 1999-11-09 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
ATE406909T1 (de) * | 1993-05-13 | 2008-09-15 | Poniard Pharmaceuticals Inc | Prävention und behandlung von pathologien, die mit einer abnormalen proliferationglatter muskelzellen verbunden sind |
US6197789B1 (en) | 1995-06-07 | 2001-03-06 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies with tamoxifen analogues |
US6323184B1 (en) | 1993-10-15 | 2001-11-27 | Thomas Jefferson University | Arteriovenous and venous graft treatments: methods and compositions |
US6133242A (en) * | 1993-10-15 | 2000-10-17 | Thomas Jefferson Univerisity | Inhibition of extracellular matrix synthesis by antisense compounds directed to nuclear proto-oncogenes |
US5449679A (en) * | 1994-07-29 | 1995-09-12 | Leonard; Robert J. | Process and products for reducing biological fluid levels of a lipid soluble waste |
US5665591A (en) * | 1994-12-06 | 1997-09-09 | Trustees Of Boston University | Regulation of smooth muscle cell proliferation |
US7611533B2 (en) * | 1995-06-07 | 2009-11-03 | Cook Incorporated | Coated implantable medical device |
EP0797998A4 (en) * | 1995-11-17 | 2003-01-15 | Toray Industries | PROTECTION FOR ENDOTHEL CELLS |
ES2314786T3 (es) | 1998-04-02 | 2009-03-16 | Genentech, Inc. | Uso de interferon gamma para el tratamiento de la hipertrofia cardiaca. |
US7524826B2 (en) * | 2000-04-14 | 2009-04-28 | Mcmaster University And Hamilton Health Sciences Corporation | Method of inhibiting the generation of active thrombin on the surface of a cell within an atherosclerotic plaque |
AU2002310922A1 (en) * | 2001-05-04 | 2002-11-18 | Institute Of Molecular And Cell Biology | Interferons in the treatment of ischemia |
AU2005211385B2 (en) | 2004-02-02 | 2008-12-11 | Ambrx, Inc. | Modified human growth hormone polypeptides and their uses |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3261761D1 (en) * | 1981-07-14 | 1985-02-14 | Efamol Ltd | Pharmaceutical and dietary composition when used for enhancement of 1-series pg production |
US5096705A (en) * | 1981-10-19 | 1992-03-17 | Genentech, Inc. | Human immune interferon |
US4454115A (en) * | 1981-10-23 | 1984-06-12 | Wisconsin Alumni Research Foundation | Method of reducing the level of low density lipoproteins in the serum of a patient |
US4483849A (en) * | 1983-01-07 | 1984-11-20 | Carter William A | Stabilization and purification of interferon with propylene glycol, resulting in a non-toxic product |
JPS6069037A (ja) * | 1983-09-26 | 1985-04-19 | Sunstar Inc | エリテマト−デス治療用外用剤 |
US4680175A (en) * | 1984-02-07 | 1987-07-14 | Interferon Sciences, Inc. | Interferon administration vehicles |
US4605555A (en) * | 1984-09-20 | 1986-08-12 | Sun Star Kabushiki Kaisha | Composition and method for treating keratosic disorder of skin and mucosa |
US4946674A (en) * | 1984-10-05 | 1990-08-07 | Bioferon Biochemische Substanzen Gmbh & Co. | Process for treatment of rheumatic diseases |
IL78444A (en) * | 1986-04-08 | 1992-05-25 | Yeda Res & Dev | Human gamma interferon-specific receptor protein,antibody against said protein,and compositions containing said protein and antibody |
US5026544A (en) * | 1988-02-16 | 1991-06-25 | Board Of Reagents, The University Of Texas System | Methods and compositions for inhibiting the growth of neoplastic cells |
-
1988
- 1988-09-30 SE SE8803472A patent/SE462364B/sv not_active IP Right Cessation
-
1989
- 1989-09-27 EP EP89850317A patent/EP0367735B1/en not_active Expired - Lifetime
- 1989-09-27 HU HU895542A patent/HU206988B/hu not_active IP Right Cessation
- 1989-09-27 IL IL9179689A patent/IL91796A/en not_active IP Right Cessation
- 1989-09-27 AT AT89850317T patent/ATE86869T1/de not_active IP Right Cessation
- 1989-09-27 WO PCT/SE1989/000520 patent/WO1990003189A1/en active Application Filing
- 1989-09-27 US US07/671,786 patent/US5208019A/en not_active Expired - Lifetime
- 1989-09-27 JP JP1510051A patent/JP2895896B2/ja not_active Expired - Lifetime
- 1989-09-27 AU AU43051/89A patent/AU623181B2/en not_active Expired
- 1989-09-27 DE DE89850317T patent/DE68905438T2/de not_active Expired - Lifetime
- 1989-09-27 KR KR1019900701144A patent/KR0137017B1/ko not_active IP Right Cessation
- 1989-09-28 NZ NZ230816A patent/NZ230816A/en unknown
- 1989-09-28 DD DD89333072A patent/DD288094A5/de unknown
- 1989-09-29 IE IE312389A patent/IE63874B1/en not_active IP Right Cessation
- 1989-09-29 CA CA000614859A patent/CA1338722C/en not_active Expired - Lifetime
- 1989-09-29 PH PH39308A patent/PH26293A/en unknown
- 1989-09-29 PT PT91863A patent/PT91863B/pt not_active IP Right Cessation
-
1991
- 1991-03-27 DK DK199100562A patent/DK174523B1/da not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008031179A (ja) * | 1995-11-30 | 2008-02-14 | Berlex Lab Inc | β−インターフェロンを使用して再狭窄を治療する方法 |
Also Published As
Publication number | Publication date |
---|---|
HUT57063A (en) | 1991-11-28 |
ATE86869T1 (de) | 1993-04-15 |
IL91796A (en) | 1994-10-07 |
IL91796A0 (en) | 1990-06-10 |
PH26293A (en) | 1992-04-10 |
EP0367735B1 (en) | 1993-03-17 |
JP2895896B2 (ja) | 1999-05-24 |
DE68905438D1 (de) | 1993-04-22 |
SE8803472A (ja) | 1988-09-30 |
SE462364B (sv) | 1990-06-18 |
DD288094A5 (de) | 1991-03-21 |
PT91863B (pt) | 1995-05-31 |
DE68905438T2 (de) | 1993-09-30 |
SE8803472D0 (sv) | 1988-09-30 |
DK56291D0 (da) | 1991-03-27 |
NZ230816A (en) | 1997-06-24 |
AU623181B2 (en) | 1992-05-07 |
DK56291A (da) | 1991-05-24 |
US5208019A (en) | 1993-05-04 |
HU895542D0 (en) | 1991-10-28 |
WO1990003189A1 (en) | 1990-04-05 |
CA1338722C (en) | 1996-11-19 |
AU4305189A (en) | 1990-04-18 |
DK174523B1 (da) | 2003-05-12 |
KR0137017B1 (ko) | 1998-04-25 |
EP0367735A1 (en) | 1990-05-09 |
PT91863A (pt) | 1990-03-30 |
IE893123L (en) | 1990-03-30 |
KR900701308A (ko) | 1990-12-01 |
IE63874B1 (en) | 1995-06-14 |
HU206988B (en) | 1993-03-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPH04500966A (ja) | 脈管狭窄の治療におけるγ―インターフェロンの使用 | |
Hansson et al. | Gamma-interferon regulates vascular smooth muscle proliferation and Ia antigen expression in vivo and in vitro. | |
JP2828250B2 (ja) | 真性糖尿病の治療 | |
US5318957A (en) | Method of stimulating angiogenesis | |
JP4307561B2 (ja) | 創傷の治癒 | |
JP2001519815A (ja) | アレルゲン誘発性障害の治療におけるラクトフェリンの使用 | |
JPH05506030A (ja) | 哺乳動物に組織修復促進の傾向を与える方法 | |
WO1995029694A1 (fr) | Accelerateur d'hydrolyse du collegene | |
JP2934023B2 (ja) | コルチコステロイド治療組成物 | |
EP3154551B1 (en) | The use of dextran sulfate having an average molecular weight below 10000 da for inducing angiogenisis in a subject | |
US20210395327A1 (en) | Growth Hormone-Releasing Hormone Antagonists and Uses Thereof | |
JP2002524420A (ja) | 脈管形成に有効な単位用量のfgf−2および使用方法 | |
JPH02209812A (ja) | 乾癬治療用医薬組成物 | |
JPH05163222A (ja) | コラーゲン過剰合成疾患治療剤 | |
JP2005531628A (ja) | 肺線維症の処置のための4−(4−メチルピペラジン−1−イルメチル)−n−[4−メチル−3−(4−ピリジン−3−イル)ピリミジン−2−イルアミノ)フェニル]−ベンズアミド | |
JPH03500660A (ja) | 血管閉塞抑制剤 | |
WO2023218048A1 (en) | Resomelagon and its derivatives for the treatment of cardiovascular disease, hypertension and atherosclerosis | |
JPH02502011A (ja) | 治療化合物、組成物及びそれらの用途 | |
JPH08508710A (ja) | 新規処置方法 | |
EP4322941A1 (en) | Combination comprising ribociclib and amcenestrant | |
JPH0429936A (ja) | 悪性脳腫瘍治療用医薬組成物 | |
JP2688733B2 (ja) | 消化管粘膜障害の予防及び治療剤 | |
CN116139247A (zh) | 一类订书肽化合物在制备治疗肺纤维化的药物中的应用 | |
JPH10504567A (ja) | 急性腎不全の治療用医薬の製造のためのザプリナストの使用 | |
JPH07138183A (ja) | 胃・十二指腸疾患治療剤 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20080305 Year of fee payment: 9 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20090305 Year of fee payment: 10 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20100305 Year of fee payment: 11 |
|
EXPY | Cancellation because of completion of term | ||
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20100305 Year of fee payment: 11 |