JP7360324B2 - 結合ポリペプチドおよびそれを作製する方法 - Google Patents

結合ポリペプチドおよびそれを作製する方法 Download PDF

Info

Publication number
JP7360324B2
JP7360324B2 JP2019533330A JP2019533330A JP7360324B2 JP 7360324 B2 JP7360324 B2 JP 7360324B2 JP 2019533330 A JP2019533330 A JP 2019533330A JP 2019533330 A JP2019533330 A JP 2019533330A JP 7360324 B2 JP7360324 B2 JP 7360324B2
Authority
JP
Japan
Prior art keywords
certain embodiments
cell
strand
cdna
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2019533330A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020511117A5 (enExample
JP2020511117A (ja
Inventor
ザッカリー シュリバー,
グレゴリー バブコック,
ルーク ロビンソン,
Original Assignee
ビステラ, インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ビステラ, インコーポレイテッド filed Critical ビステラ, インコーポレイテッド
Publication of JP2020511117A publication Critical patent/JP2020511117A/ja
Publication of JP2020511117A5 publication Critical patent/JP2020511117A5/ja
Priority to JP2023169621A priority Critical patent/JP2023169422A/ja
Application granted granted Critical
Publication of JP7360324B2 publication Critical patent/JP7360324B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1093General methods of preparing gene libraries, not provided for in other subgroups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/005Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Microbiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2019533330A 2016-12-23 2017-12-22 結合ポリペプチドおよびそれを作製する方法 Active JP7360324B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023169621A JP2023169422A (ja) 2016-12-23 2023-09-29 結合ポリペプチドおよびそれを作製する方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662438712P 2016-12-23 2016-12-23
US62/438,712 2016-12-23
PCT/US2017/068204 WO2018119402A1 (en) 2016-12-23 2017-12-22 Binding polypeptides and methods of making the same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023169621A Division JP2023169422A (ja) 2016-12-23 2023-09-29 結合ポリペプチドおよびそれを作製する方法

Publications (3)

Publication Number Publication Date
JP2020511117A JP2020511117A (ja) 2020-04-16
JP2020511117A5 JP2020511117A5 (enExample) 2021-02-12
JP7360324B2 true JP7360324B2 (ja) 2023-10-12

Family

ID=61054491

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019533330A Active JP7360324B2 (ja) 2016-12-23 2017-12-22 結合ポリペプチドおよびそれを作製する方法
JP2023169621A Pending JP2023169422A (ja) 2016-12-23 2023-09-29 結合ポリペプチドおよびそれを作製する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023169621A Pending JP2023169422A (ja) 2016-12-23 2023-09-29 結合ポリペプチドおよびそれを作製する方法

Country Status (15)

Country Link
US (2) US11820979B2 (enExample)
EP (1) EP3559028A1 (enExample)
JP (2) JP7360324B2 (enExample)
KR (2) KR102702552B1 (enExample)
CN (1) CN110366557B (enExample)
AU (1) AU2017382367B2 (enExample)
BR (1) BR112019013096A2 (enExample)
CA (1) CA3045696A1 (enExample)
CL (2) CL2019001757A1 (enExample)
CO (1) CO2019006663A2 (enExample)
IL (2) IL315727A (enExample)
MX (1) MX2019007356A (enExample)
MY (1) MY201744A (enExample)
RU (1) RU2019123063A (enExample)
WO (1) WO2018119402A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3781677A4 (en) * 2018-04-16 2022-01-19 University of Massachusetts COMPOSITIONS AND METHODS FOR IMPROVED GENE EDITTING
CN109161572B (zh) * 2018-07-05 2021-11-12 中国海洋大学 单链环状核酸及其制备方法和应用
EP3876956A4 (en) 2018-11-08 2022-12-28 The Regents of The University of California SYSTEMS AND METHODS FOR TARGETING CANCER CELLS

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010022738A1 (en) 2008-08-29 2010-03-04 Symphogen A/S Method for cloning avian-derived antibodies
WO2013092716A1 (en) 2011-12-21 2013-06-27 F. Hoffmann-La Roche Ag Rapid method for cloning and expression of cognate antibody variable region gene segments
WO2015166272A2 (en) 2014-05-02 2015-11-05 Iontas Limited Preparation of libraries of protein variants expressed in eukaryotic cells and use for selecting binding molecules

Family Cites Families (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
JPS6147500A (ja) 1984-08-15 1986-03-07 Res Dev Corp Of Japan キメラモノクロ−ナル抗体及びその製造法
EP0173494A3 (en) 1984-08-27 1987-11-25 The Board Of Trustees Of The Leland Stanford Junior University Chimeric receptors by dna splicing and expression
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
JPS61134325A (ja) 1984-12-04 1986-06-21 Teijin Ltd ハイブリツド抗体遺伝子の発現方法
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
AU600575B2 (en) 1987-03-18 1990-08-16 Sb2, Inc. Altered antibodies
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
EP1541682A3 (en) 1988-09-02 2005-07-06 Dyax Corp. Generation and selection of recombinant varied binding proteins
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
GB8905669D0 (en) 1989-03-13 1989-04-26 Celltech Ltd Modified antibodies
WO1991000906A1 (en) 1989-07-12 1991-01-24 Genetics Institute, Inc. Chimeric and transgenic animals capable of producing human antibodies
ES2087997T3 (es) 1990-01-12 1996-08-01 Cell Genesys Inc Generacion de anticuerpos xenogenicos.
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
JPH06508511A (ja) 1990-07-10 1994-09-29 ケンブリッジ アンティボディー テクノロジー リミティド 特異的な結合ペアーの構成員の製造方法
WO1992003917A1 (en) 1990-08-29 1992-03-19 Genpharm International Homologous recombination in mammalian cells
ES2108048T3 (es) 1990-08-29 1997-12-16 Genpharm Int Produccion y utilizacion de animales inferiores transgenicos capaces de producir anticuerpos heterologos.
DE69129154T2 (de) 1990-12-03 1998-08-20 Genentech, Inc., South San Francisco, Calif. Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften
DE69233769D1 (de) 1991-03-01 2009-09-24 Dyax Corp Chimäres Protein mit Mikroprotein mit zwei oder mehr Disulfidbindungen und Ausgestaltungen davon
ATE414768T1 (de) 1991-04-10 2008-12-15 Scripps Research Inst Bibliotheken heterodimerer rezeptoren mittels phagemiden
DE69233482T2 (de) 1991-05-17 2006-01-12 Merck & Co., Inc. Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen
DE4122599C2 (de) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid zum Screenen von Antikörpern
EP1498427B1 (en) 1992-08-21 2009-12-16 Vrije Universiteit Brussel Immunoglobulins devoid of light chains
US5851804A (en) 1996-05-06 1998-12-22 Apollon, Inc. Chimeric kanamycin resistance gene
IL127624A0 (en) 1996-06-17 1999-10-28 Biodynamics Associates Method and kits for preparing multicomponent nucleic acid constructs
US20020086330A1 (en) * 2000-01-31 2002-07-04 Rosen Craig A. Nucleic acids, proteins, and antibodies
AU2001232204A1 (en) 2000-02-22 2001-09-03 Ahuva Nissim Chimeric and tcr phage display libraries, chimeric and tcr reagents and methods of use thereof
KR101135134B1 (ko) * 2003-09-18 2012-04-13 심포젠 에이/에스 관심있는 서열을 결합시키는 방법
TWI333977B (en) * 2003-09-18 2010-12-01 Symphogen As Method for linking sequences of interest
US20060199191A1 (en) 2004-12-13 2006-09-07 Demian Obregon Methods and compositions for the synthesis of RNA and DNA
CN101370832B (zh) * 2005-12-02 2014-07-02 健泰科生物技术公司 结合多肽及其用途
MX338151B (es) * 2007-03-01 2016-04-05 Symphogen As Composiciones de anticuerpo recombinante anti-receptor de factor de crecimiento epidermico.
CA2677771A1 (en) 2007-03-01 2008-09-04 Symphogen A/S Method for cloning cognate antibodies
US8877688B2 (en) 2007-09-14 2014-11-04 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
JP5933894B2 (ja) 2007-09-14 2016-06-15 アディマブ, エルエルシー 合理的に設計された、合成抗体ライブラリおよびその使用
SI2274008T1 (sl) * 2008-03-27 2014-08-29 Zymogenetics, Inc. Sestavki in metode za zaviranje PDGFRBETA in VEGF-A
WO2010005593A1 (en) * 2008-07-11 2010-01-14 President And Fellows Of Harvard College Systems and methods of droplet-based selection
JP5829606B2 (ja) 2009-06-29 2015-12-09 カリフォルニア・インスティテュート・オブ・テクノロジーCalifornia Institute Oftechnology 単一細胞からの未知の再配列されたt細胞受容体の単離
IT1395574B1 (it) 2009-09-14 2012-10-16 Guala Dispensing Spa Dispositivo di erogazione
JP2013512691A (ja) * 2009-12-07 2013-04-18 プログノシス バイオサイエンシズ インコーポレイテッド ペプチド提示アレイ
WO2011146514A2 (en) 2010-05-17 2011-11-24 The Board Of Regents Of The University Of Texas System Rapid isolation of monoclonal antibodies from animals
WO2012032181A2 (en) * 2010-09-10 2012-03-15 Allozyne, Inc Novel antibody derivatives
US20140057799A1 (en) 2010-12-16 2014-02-27 Gigagen System and Methods for Massively Parallel Analysis of Nucleic Acids in Single Cells
EP3421592B1 (en) 2011-04-28 2023-09-13 The Board of Trustees of the Leland Stanford Junior University Identification of polynucleotides associated with a sample
EP2739733B1 (en) 2011-08-03 2017-11-22 Texas Biomedical Research Insitute Nucleic acid compositions, methods and kits for rapid pairing of affinity agents
CA2887880A1 (en) 2011-11-23 2013-05-30 The Board Of Regents Of The University Of Texas System Proteomic identification of antibodies
EP2809783A2 (en) 2012-02-02 2014-12-10 Invenra, Inc. High throughput screen for biologically active polypeptides
EP2626433B1 (en) * 2012-02-09 2017-04-12 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Method for linking nucleic acids in a microsome from endoplasmatic reticuli
WO2013188872A1 (en) * 2012-06-15 2013-12-19 The Board Of Regents Of The University Of Texas System High throughput sequencing of multiple transcripts of a single cell
CA2876209A1 (en) 2012-06-15 2013-12-19 Adaptive Biotechnologies Corporation Uniquely tagged rearranged adaptive immune receptor genes in a complex gene set
WO2014043813A1 (en) 2012-09-19 2014-03-27 British Columbia Cancer Agency Branch Immune repertoire profiling
WO2014144495A1 (en) 2013-03-15 2014-09-18 Abvitro, Inc. Single cell bar-coding for antibody discovery
SG11201506991VA (en) 2013-03-15 2015-10-29 Adaptive Biotechnologies Corp Uniquely tagged rearranged adaptive immune receptor genes in a complex gene set
RU2578009C2 (ru) 2013-05-08 2016-03-20 Закрытое акционерное общество "ЕВРОГЕН" Способ идентификации нативных пар фрагментов днк или рнк, присутствующих в одних и тех же живых клетках
AU2014315287A1 (en) * 2013-09-03 2015-03-12 Moderna Therapeutics, Inc. Chimeric polynucleotides
GB201402591D0 (en) 2014-02-14 2014-04-02 Memo Therapeutics Ag Method for recovering two or more genes, or gene products, encoding an immunoreceptor
US10066265B2 (en) 2014-04-01 2018-09-04 Adaptive Biotechnologies Corp. Determining antigen-specific t-cells
US10202640B2 (en) 2014-05-07 2019-02-12 The Board Of Trustees Of The Leland Stanford Junior University Single cell analysis of T cells using high-throughput multiplex amplification and deep sequencing
CA2947320C (en) 2014-05-22 2023-03-14 The University Of British Columbia Methods for determining lymphocyte receptor chain pairs
WO2016044227A1 (en) 2014-09-15 2016-03-24 Abvitro, Inc. High-throughput nucleotide library sequencing
CA2966201A1 (en) 2014-10-29 2016-05-06 Adaptive Biotechnologies Corp. Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples
US10513733B2 (en) 2015-03-23 2019-12-24 Board Of Regents, The University Of Texas System High throughout sequencing of paired VH and VL transcripts from B cells secreting antigen-specific antibodies
WO2016176322A1 (en) 2015-04-27 2016-11-03 Abvitro Llc Methods of sequencing, determining, pairing, and validating therapeutic agents and disease specific antigens
US9422547B1 (en) 2015-06-09 2016-08-23 Gigagen, Inc. Recombinant fusion proteins and libraries from immune cell repertoires
WO2017180738A1 (en) * 2016-04-12 2017-10-19 Medimmune, Llc Immune repertoire mining

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010022738A1 (en) 2008-08-29 2010-03-04 Symphogen A/S Method for cloning avian-derived antibodies
JP2012500634A (ja) 2008-08-29 2012-01-12 シムフォゲン・アクティーゼルスカブ 鳥類から得られた抗体のクローニング方法
WO2013092716A1 (en) 2011-12-21 2013-06-27 F. Hoffmann-La Roche Ag Rapid method for cloning and expression of cognate antibody variable region gene segments
WO2015166272A2 (en) 2014-05-02 2015-11-05 Iontas Limited Preparation of libraries of protein variants expressed in eukaryotic cells and use for selecting binding molecules

Also Published As

Publication number Publication date
AU2017382367A1 (en) 2019-06-13
IL315727A (en) 2024-11-01
EP3559028A1 (en) 2019-10-30
MY201744A (en) 2024-03-15
CL2022000454A1 (es) 2023-03-24
CN110366557A (zh) 2019-10-22
WO2018119402A1 (en) 2018-06-28
CA3045696A1 (en) 2018-06-28
IL267565A (en) 2019-08-29
JP2023169422A (ja) 2023-11-29
CO2019006663A2 (es) 2019-06-28
MX2019007356A (es) 2019-09-05
JP2020511117A (ja) 2020-04-16
CL2019001757A1 (es) 2019-11-29
KR20240133790A (ko) 2024-09-04
CN110366557B (zh) 2024-04-09
US11820979B2 (en) 2023-11-21
IL267565B2 (en) 2025-02-01
RU2019123063A3 (enExample) 2021-11-29
US20180201926A1 (en) 2018-07-19
IL267565B1 (en) 2024-10-01
RU2019123063A (ru) 2021-01-26
US20240141334A1 (en) 2024-05-02
AU2017382367B2 (en) 2024-11-21
KR102702552B1 (ko) 2024-09-03
KR20190111036A (ko) 2019-10-01
BR112019013096A2 (pt) 2019-12-17

Similar Documents

Publication Publication Date Title
US20250382621A1 (en) Immune effector cell therapies with enhanced efficacy
JP2023169422A (ja) 結合ポリペプチドおよびそれを作製する方法
JP7483857B2 (ja) インターロイキン-2作用物質およびその使用
JP6731403B2 (ja) 免疫応答およびがん治療の増強に使用するための組成物および方法
JP2021118704A (ja) 親和性−オリゴヌクレオチドコンジュゲートおよびその使用
JP2021519072A (ja) ガイダンス及びナビゲーションコントロール蛋白質並びにその生産及び使用方法
CN110891650A (zh) 制导和导航控制蛋白及其制造和使用方法
CN110121510A (zh) 程序性细胞死亡(pd-1)的单结构域抗体
CN110214152A (zh) 模块化四聚体双特异性抗体平台
TW202346315A (zh) 治療及診斷劑以及其用途
HK40015938B (zh) 结合多肽及其制备方法
CN117677635A (zh) 新颖pd-1结合域
NZ753978A (en) Binding polypeptides and methods of making the same
HK40015938A (en) Binding polypeptides and methods of making the same
NZ795976A (en) Binding polypeptides and methods of making the same
KR102943539B1 (ko) 인터류킨-2 작용제 및 이의 용도
TW202304976A (zh) 包含新穎pd-1結合域之多特異性結合部分
TW201625697A (zh) 用於增強之免疫反應之組合物及使用方法,及癌症療法
HK1258783B (zh) 用於癌症治疗的诱导细胞损伤的治疗药物

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190904

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20201222

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20201222

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20211228

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20220325

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20220525

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20220628

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20221025

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20230124

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20230324

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230425

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20230731

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20230830

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20230929

R150 Certificate of patent or registration of utility model

Ref document number: 7360324

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150