CN110366557B - 结合多肽及其制备方法 - Google Patents

结合多肽及其制备方法 Download PDF

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Publication number
CN110366557B
CN110366557B CN201780086589.3A CN201780086589A CN110366557B CN 110366557 B CN110366557 B CN 110366557B CN 201780086589 A CN201780086589 A CN 201780086589A CN 110366557 B CN110366557 B CN 110366557B
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cell
cdna
sequence
chain
encoding
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Chinese (zh)
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CN110366557A (zh
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Z·西里瓦
G·巴布考克
L·罗宾森
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Visterra Inc
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Visterra Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/005—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Microbiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201780086589.3A 2016-12-23 2017-12-22 结合多肽及其制备方法 Active CN110366557B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662438712P 2016-12-23 2016-12-23
US62/438,712 2016-12-23
PCT/US2017/068204 WO2018119402A1 (en) 2016-12-23 2017-12-22 Binding polypeptides and methods of making the same

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CN110366557A CN110366557A (zh) 2019-10-22
CN110366557B true CN110366557B (zh) 2024-04-09

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US (2) US11820979B2 (enExample)
EP (1) EP3559028A1 (enExample)
JP (2) JP7360324B2 (enExample)
KR (2) KR102702552B1 (enExample)
CN (1) CN110366557B (enExample)
AU (1) AU2017382367B2 (enExample)
BR (1) BR112019013096A2 (enExample)
CA (1) CA3045696A1 (enExample)
CL (2) CL2019001757A1 (enExample)
CO (1) CO2019006663A2 (enExample)
IL (2) IL315727A (enExample)
MX (1) MX2019007356A (enExample)
MY (1) MY201744A (enExample)
RU (1) RU2019123063A (enExample)
WO (1) WO2018119402A1 (enExample)

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Publication number Priority date Publication date Assignee Title
EP3781677A4 (en) * 2018-04-16 2022-01-19 University of Massachusetts COMPOSITIONS AND METHODS FOR IMPROVED GENE EDITTING
CN109161572B (zh) * 2018-07-05 2021-11-12 中国海洋大学 单链环状核酸及其制备方法和应用
EP3876956A4 (en) 2018-11-08 2022-12-28 The Regents of The University of California SYSTEMS AND METHODS FOR TARGETING CANCER CELLS

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AU2017382367A1 (en) 2019-06-13
JP7360324B2 (ja) 2023-10-12
IL315727A (en) 2024-11-01
EP3559028A1 (en) 2019-10-30
MY201744A (en) 2024-03-15
CL2022000454A1 (es) 2023-03-24
CN110366557A (zh) 2019-10-22
WO2018119402A1 (en) 2018-06-28
CA3045696A1 (en) 2018-06-28
IL267565A (en) 2019-08-29
JP2023169422A (ja) 2023-11-29
CO2019006663A2 (es) 2019-06-28
MX2019007356A (es) 2019-09-05
JP2020511117A (ja) 2020-04-16
CL2019001757A1 (es) 2019-11-29
KR20240133790A (ko) 2024-09-04
US11820979B2 (en) 2023-11-21
IL267565B2 (en) 2025-02-01
RU2019123063A3 (enExample) 2021-11-29
US20180201926A1 (en) 2018-07-19
IL267565B1 (en) 2024-10-01
RU2019123063A (ru) 2021-01-26
US20240141334A1 (en) 2024-05-02
AU2017382367B2 (en) 2024-11-21
KR102702552B1 (ko) 2024-09-03
KR20190111036A (ko) 2019-10-01
BR112019013096A2 (pt) 2019-12-17

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