JP7030704B2 - 二重特異性シグナル伝達物質およびその使用 - Google Patents

二重特異性シグナル伝達物質およびその使用 Download PDF

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JP7030704B2
JP7030704B2 JP2018541357A JP2018541357A JP7030704B2 JP 7030704 B2 JP7030704 B2 JP 7030704B2 JP 2018541357 A JP2018541357 A JP 2018541357A JP 2018541357 A JP2018541357 A JP 2018541357A JP 7030704 B2 JP7030704 B2 JP 7030704B2
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antigen
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JP2019506869A (ja
JP2019506869A5 (enExample
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クレイ，ニコライ
タベルニエル，ジャン
リント，サンドラ ヴァン
カウウェルズ，アンジェ
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オリオニス バイオサイエンシズ ビーブイ
ブイアイビー ブイゼットダブリュー
ユニバーシテイト ヘント
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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JP2018541357A 2016-02-05 2017-02-06 二重特異性シグナル伝達物質およびその使用 Active JP7030704B2 (ja)

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US201662291769P 2016-02-05 2016-02-05
US201662291776P 2016-02-05 2016-02-05
US201662291779P 2016-02-05 2016-02-05
US201662291772P 2016-02-05 2016-02-05
US201662291774P 2016-02-05 2016-02-05
US62/291,772 2016-02-05
US62/291,769 2016-02-05
US62/291,776 2016-02-05
US62/291,779 2016-02-05
US62/291,774 2016-02-05
US201662335880P 2016-05-13 2016-05-13
US201662335968P 2016-05-13 2016-05-13
US201662335979P 2016-05-13 2016-05-13
US201662335965P 2016-05-13 2016-05-13
US201662336030P 2016-05-13 2016-05-13
US62/335,880 2016-05-13
US62/335,979 2016-05-13
US62/335,968 2016-05-13
US62/335,965 2016-05-13
US62/336,030 2016-05-13
US201662353607P 2016-06-23 2016-06-23
US62/353,607 2016-06-23
US201662411805P 2016-10-24 2016-10-24
US62/411,805 2016-10-24
PCT/EP2017/052550 WO2017134305A1 (en) 2016-02-05 2017-02-06 Bispecific signaling agents and uses thereof

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CN (9) CN109071663B (enExample)
CA (4) CA3013555A1 (enExample)
DK (3) DK3411065T3 (enExample)
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JP2022084614A (ja) * 2016-02-05 2022-06-07 オリオニス バイオサイエンシズ ビーブイ 二重特異性シグナル伝達物質およびその使用

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EP3455245A2 (en) * 2016-05-13 2019-03-20 Orionis Biosciences NV Therapeutic targeting of non-cellular structures
US10906985B2 (en) 2017-02-06 2021-02-02 Orionis Biosciences, Inc. Targeted engineered interferon and uses thereof
EP3577133A1 (en) * 2017-02-06 2019-12-11 Orionis Biosciences NV Targeted chimeric proteins and uses thereof
BR112019018915A2 (pt) 2017-03-15 2020-04-14 Pandion Therapeutics Inc imunotolerância direcionada
CN111010866A (zh) 2017-05-24 2020-04-14 潘迪恩治疗公司 靶向免疫耐受性
AU2018297248A1 (en) 2017-07-03 2020-02-20 Torque Therapeutics, Inc. Fusion molecules targeting immune regulatory cells and uses thereof
TN2020000015A1 (en) 2017-08-03 2021-10-04 Amgen Inc Interleukin-21 muteins and methods of treatment
SG11202001063QA (en) * 2017-08-09 2020-03-30 Orionis Biosciences Inc Clec9a binding agents and use thereof
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