JP6716566B2 - 近接センサ付き薬物送達装置 - Google Patents

近接センサ付き薬物送達装置 Download PDF

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JP6716566B2
JP6716566B2 JP2017532778A JP2017532778A JP6716566B2 JP 6716566 B2 JP6716566 B2 JP 6716566B2 JP 2017532778 A JP2017532778 A JP 2017532778A JP 2017532778 A JP2017532778 A JP 2017532778A JP 6716566 B2 JP6716566 B2 JP 6716566B2
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proximity sensor
plunger
housing
sensor
reservoir
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JP2017538511A5 (cg-RX-API-DMAC7.html
JP2017538511A (ja
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マッカロー，アダム・ビー
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アムジエン・インコーポレーテツド
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    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
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    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
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    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14526—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons the piston being actuated by fluid pressure
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    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1454—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons spring-actuated, e.g. by a clockwork
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    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
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    • A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/5086—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile for indicating if defective, used, tampered with or unsterile
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    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
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    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1581—Right-angle needle-type devices
    • A—HUMAN NECESSITIES
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    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
    • A—HUMAN NECESSITIES
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    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
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    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/13—General characteristics of the apparatus with means for the detection of operative contact with patient, e.g. lip sensor
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    • A61M2205/3331—Pressure; Flow
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    • A61M2205/8225—Gas operated using incorporated gas cartridges for the driving gas
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    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
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    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16877—Adjusting flow; Devices for setting a flow rate
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    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2046—Media being expelled from injector by gas generation, e.g. explosive charge

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
JP2017532778A 2014-12-19 2015-12-18 近接センサ付き薬物送達装置 Active JP6716566B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462094395P 2014-12-19 2014-12-19
US62/094,395 2014-12-19
PCT/US2015/066597 WO2016100781A1 (en) 2014-12-19 2015-12-18 Drug delivery device with proximity sensor

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2020099954A Division JP7049394B2 (ja) 2014-12-19 2020-06-09 近接センサ付き薬物送達装置
JP2020099955A Division JP7049395B2 (ja) 2014-12-19 2020-06-09 近接センサ付き薬物送達装置

Publications (3)

Publication Number Publication Date
JP2017538511A JP2017538511A (ja) 2017-12-28
JP2017538511A5 JP2017538511A5 (cg-RX-API-DMAC7.html) 2018-12-06
JP6716566B2 true JP6716566B2 (ja) 2020-07-01

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JP2017532778A Active JP6716566B2 (ja) 2014-12-19 2015-12-18 近接センサ付き薬物送達装置
JP2020099955A Active JP7049395B2 (ja) 2014-12-19 2020-06-09 近接センサ付き薬物送達装置
JP2020099954A Active JP7049394B2 (ja) 2014-12-19 2020-06-09 近接センサ付き薬物送達装置
JP2022047935A Active JP7371158B2 (ja) 2014-12-19 2022-03-24 近接センサ付き薬物送達装置

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JP2020099955A Active JP7049395B2 (ja) 2014-12-19 2020-06-09 近接センサ付き薬物送達装置
JP2020099954A Active JP7049394B2 (ja) 2014-12-19 2020-06-09 近接センサ付き薬物送達装置
JP2022047935A Active JP7371158B2 (ja) 2014-12-19 2022-03-24 近接センサ付き薬物送達装置

Country Status (5)

Country Link
US (5) US10799630B2 (cg-RX-API-DMAC7.html)
EP (2) EP3848072A1 (cg-RX-API-DMAC7.html)
JP (4) JP6716566B2 (cg-RX-API-DMAC7.html)
ES (1) ES2898469T3 (cg-RX-API-DMAC7.html)
WO (1) WO2016100781A1 (cg-RX-API-DMAC7.html)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2354107T3 (es) 2005-09-12 2011-03-10 Unomedical A/S Dispositivo de inserción para un equipo de infusión con una primera y segunda unidades de resorte.
WO2009044401A2 (en) 2007-10-02 2009-04-09 Yossi Gross External drug pump
CN104474606B (zh) * 2009-10-13 2017-04-26 瓦莱里塔斯公司 流体输送装置
WO2011121023A1 (en) 2010-03-30 2011-10-06 Unomedical A/S Medical device
WO2012123274A1 (en) 2011-03-14 2012-09-20 Unomedical A/S Inserter system with transport protection
EP2583715A1 (en) 2011-10-19 2013-04-24 Unomedical A/S Infusion tube system and method for manufacture
CN105007964B (zh) 2013-02-19 2018-01-30 诺和诺德股份有限公司 用于给药装置的剂量捕获筒模块
US9750886B2 (en) 2013-02-19 2017-09-05 Novo Nordisk A/S Drug delivery device with dose capturing module
WO2014128156A1 (en) 2013-02-19 2014-08-28 Novo Nordisk A/S Rotary sensor module with axial switch
JP6474802B2 (ja) * 2013-07-17 2019-02-27 サノフイＳａｎｏｆｉ 薬物送達デバイスのための駆動構成
EP3071259B1 (en) 2013-11-21 2019-04-10 Novo Nordisk A/S Rotary sensor assembly with axial switch and redundancy feature
CN105722540B (zh) 2013-11-21 2019-06-28 诺和诺德股份有限公司 具有空间有效设计的旋转传感器组件
JP2016538060A (ja) * 2013-11-21 2016-12-08 ノボ・ノルデイスク・エー／エス 再同期化機構を備えた回転センサモジュール
EP3848072A1 (en) 2014-12-19 2021-07-14 Amgen Inc. Drug delivery device with proximity sensor
CN107635527B (zh) 2015-03-10 2021-04-23 里珍纳龙药品有限公司 无菌刺穿系统和方法
US10576207B2 (en) 2015-10-09 2020-03-03 West Pharma. Services IL, Ltd. Angled syringe patch injector
CN113648488B (zh) 2015-10-09 2024-03-29 西医药服务以色列分公司 至预填充的流体储存器的弯曲流体路径附加装置
US11357912B2 (en) 2016-01-19 2022-06-14 Unomedical A/S Cannula and infusion devices
US10610638B2 (en) 2016-01-21 2020-04-07 West Pharma. Services IL, Ltd. Force containment in an automatic injector
JP6885960B2 (ja) 2016-01-21 2021-06-16 ウェスト ファーマ サービシーズ イスラエル リミテッド 視覚的インジケータを有する薬剤デリバリデバイス
US10646643B2 (en) 2016-01-21 2020-05-12 West Pharma. Services IL, Ltd. Needle insertion and retraction mechanism
JOP20170042B1 (ar) 2016-02-12 2022-09-15 Amgen Inc وسيلة توصيل عقار، طريقة تصنيعه وطريقة استخدامه
WO2017161076A1 (en) 2016-03-16 2017-09-21 Medimop Medical Projects Ltd. Staged telescopic screw assembly having different visual indicators
US11129936B2 (en) 2016-04-08 2021-09-28 Amgen Inc. Drug delivery device, method of manufacture, and method of use
GB2606087B (en) 2016-06-06 2023-03-08 E3D Agricultural Cooporative Association Ltd Multiple use computerized injector
GB2552340A (en) 2016-07-19 2018-01-24 Owen Mumford Ltd Medicament delivery device
EP3490643B1 (en) 2016-08-01 2021-10-27 West Pharma. Services Il, Ltd. Anti-rotation cartridge pin
US11730892B2 (en) 2016-08-01 2023-08-22 West Pharma. Services IL, Ltd. Partial door closure prevention spring
US20200016333A1 (en) * 2016-09-27 2020-01-16 Sanofi-Aventis Deutschland Gmbh A medicament delivery device
EP3522948B1 (en) * 2016-10-10 2020-07-22 West Pharma. Services Il, Ltd. Needle insertion and retraction mechanism
WO2018096534A1 (en) 2016-11-22 2018-05-31 Sorrel Medical Ltd. Apparatus for delivering a therapeutic substance
US11355225B2 (en) 2017-03-15 2022-06-07 Novartis Ag System for use of a pharmaceutical product
CN110520931B (zh) 2017-03-15 2024-06-04 诺瓦提斯公司 用于将药品给药的系统
CN110546713B (zh) 2017-03-15 2023-10-27 诺瓦提斯公司 医疗装置、编程装置、无线终端和医疗系统
WO2018166701A1 (en) * 2017-03-16 2018-09-20 Novartis Ag Injector device
US20200114068A1 (en) * 2017-03-16 2020-04-16 Novartis Ag Injector device
JP7130658B2 (ja) 2017-03-16 2022-09-05 ノバルティス アーゲー 注射器装置
HUE059229T2 (hu) 2017-05-05 2022-10-28 Regeneron Pharma Automata befecskendezõkészülék
WO2018222521A1 (en) 2017-05-30 2018-12-06 West Pharma. Services IL, Ltd. Modular drive train for wearable injector
US20190054246A1 (en) * 2017-08-17 2019-02-21 Qualcomm Incorporated Medicine delivery device
CA3073605C (en) * 2017-08-21 2023-03-21 Eli Lilly And Company Medication delivery device with sensing system
EP4306146A3 (en) * 2017-09-25 2024-01-24 Insulet Corporation Pre-filled cartridge-based drug delivery device
EP4257164A3 (en) * 2017-10-06 2024-01-17 Amgen Inc. Drug delivery device with interlock assembly and related method of assembly
CN111225696B (zh) * 2017-11-10 2023-07-18 安进公司 用于药物递送装置的柱塞
JP7611699B2 (ja) 2018-02-16 2025-01-10 デバイオテック・ソシエテ・アノニム 薬物送達システムの状態表示器
CN108392699B (zh) * 2018-04-04 2024-07-12 杨一博 用于注射的装置及其方法
US20190374722A1 (en) * 2018-06-08 2019-12-12 Abbvie Inc. Injection device with end of dose indicator
AU2019300452A1 (en) * 2018-07-11 2021-01-07 Debiotech S.A. Drug delivery system
EP3632487B1 (en) 2018-10-05 2024-06-12 LTS Device Technologies Ltd Triggering sequence
JP2022519414A (ja) * 2018-11-13 2022-03-24 ウェスト ファーマ サービシーズ イスラエル リミテッド 注射器の針の深さセンサー
BR112021016439A2 (pt) 2019-02-26 2021-11-09 Becton Dickinson France Autoinjetor com indicador de áudio
MA55077A (fr) 2019-02-27 2022-01-05 Lilly Co Eli Dispositif d'administration de médicament avec système de détection
WO2020232565A1 (zh) * 2019-05-17 2020-11-26 上海移宇科技股份有限公司 药物输注装置
WO2020236796A1 (en) 2019-05-20 2020-11-26 Unomedical A/S Rotatable infusion device and methods thereof
WO2020261106A1 (en) * 2019-06-25 2020-12-30 Quio Technologies Llc A system with a monitoring device
EP3990059A1 (en) * 2019-06-26 2022-05-04 Sanofi Injection device with a filling level indicator
CN114450047B (zh) * 2019-07-24 2025-04-11 因内博注射剂公司 医用流体注射和转移装置及方法
WO2021050384A1 (en) * 2019-09-11 2021-03-18 Eli Lilly And Company Medication delivery device with needle carrier
CA3155912A1 (en) 2019-09-25 2021-04-01 Janssen Pharmaceuticals, Inc. Interconnection of drug administration systems
BR112022005788A2 (pt) 2019-10-01 2022-06-21 Unomedical As Conector
EP4041341A1 (en) * 2019-10-08 2022-08-17 Amgen Inc. Needle insertion mechanism for drug delivery device
US12440373B2 (en) * 2020-06-11 2025-10-14 AesculaTech, Inc. Device for controlled injection across a variety of material properties
CN115776902A (zh) * 2020-06-26 2023-03-10 阿克蒂瓦克斯股份有限公司 利用一次容器的均匀压力施加的自动注射器
AU2021360288A1 (en) * 2020-10-15 2023-05-11 Alcon Inc. Wireless injector
US11951281B2 (en) 2020-11-11 2024-04-09 Medtronic Minimed, Inc. Fluid conduit insertion devices
US12447269B2 (en) * 2020-11-11 2025-10-21 Medtronic Minimed, Inc. Torsional insertion devices
US11464902B1 (en) 2021-02-18 2022-10-11 Fresenius Kabi Deutschland Gmbh Wearable medicament delivery device with compressible reservoir and method of use thereof
US11311666B1 (en) 2021-02-18 2022-04-26 Fresenius Kabi Deutschland Gmbh Modular wearable medicament delivery device and method of use thereof
US11872369B1 (en) 2021-02-18 2024-01-16 Fresenius Kabi Deutschland Gmbh Wearable medicament delivery device with leakage and skin contact sensing and method of use thereof
US11426523B1 (en) 2021-02-19 2022-08-30 Fresenius Kabi Deutschland Gmbh Drug delivery assembly including a removable cartridge
US11633537B1 (en) 2021-02-19 2023-04-25 Fresenius Kabi Deutschland Gmbh Drug delivery assembly including a pre-filled cartridge
US11406755B1 (en) 2021-02-19 2022-08-09 Fresenius Kabi Deutschland Gmbh Sensing fluid flow irregularities in an on-body injector
US11344682B1 (en) 2021-02-19 2022-05-31 Fresenius Kabi Deutschland Gmbh Drug supply cartridge with visual use indicator and delivery devices that use the same
US11413394B1 (en) 2021-02-19 2022-08-16 Fresenius Kabi Deutschland Gmbh Display for wearable drug delivery device
US11497847B1 (en) 2021-02-19 2022-11-15 Fresenius Kabi Deutschland Gmbh Wearable injector with adhesive substrate
US11607505B1 (en) 2021-02-19 2023-03-21 Fresenius Kabi Deutschland Gmbh Wearable injector with sterility sensors
EP4059541A1 (en) * 2021-03-15 2022-09-21 Sensile Medical AG Drug delivery device
US11529459B1 (en) 2021-04-30 2022-12-20 Fresenius Kabi Deutschland Gmbh Wearable injector with adhesive module
US11419976B1 (en) 2021-04-30 2022-08-23 Fresenius Kabi Deutschland Gmbh Wearable drug delivery device with pressurized fluid dispensing
US11351300B1 (en) 2021-04-30 2022-06-07 Fresenius Kabl Deutschland GmbH Drug dispensing system with replaceable drug supply cartridges
US11504470B1 (en) 2021-04-30 2022-11-22 Fresenius Kabi Deutschland Gmbh Deformable drug reservoir for wearable drug delivery device
US11717608B1 (en) 2021-05-03 2023-08-08 Fresenius Kabi Deutschland Gmbh Drug delivery assembly including an adhesive pad
US11484646B1 (en) 2021-05-04 2022-11-01 Fresenius Kabi Deutschland Gmbh Sealing systems for a reservoir of an on-body injector
USD1007676S1 (en) 2021-11-16 2023-12-12 Regeneron Pharmaceuticals, Inc. Wearable autoinjector
GB2621636B (en) * 2022-08-19 2024-11-27 Shaily Uk Ltd Medicament delivery device
EP4615347A1 (en) * 2022-11-09 2025-09-17 The General Hospital Corporation Systems and methods for hair transplantation with split needle device
US20250195752A1 (en) * 2023-12-19 2025-06-19 Becton, Dickinson And Company Fillable medicament delivery device

Family Cites Families (305)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6241704B1 (en) 1901-11-22 2001-06-05 Sims Deltec, Inc. Drug pump systems and methods
US4386606A (en) 1979-12-26 1983-06-07 Waters Instruments, Inc. Syringe lock
US4417889A (en) 1980-12-31 1983-11-29 Choi Soo Bong Device for a portable automatic syringe
NZ210501A (en) 1983-12-13 1991-08-27 Kirin Amgen Inc Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
US4703008A (en) 1983-12-13 1987-10-27 Kiren-Amgen, Inc. DNA sequences encoding erythropoietin
KR850004274A (ko) 1983-12-13 1985-07-11 원본미기재 에리트로포이에틴의 제조방법
US4559038A (en) 1984-10-19 1985-12-17 Deltec Systems, Inc. Drug delivery system
US5222362A (en) 1989-01-10 1993-06-29 Maus Daryl D Heat-activated drug delivery system and thermal actuators therefor
KR100221066B1 (ko) 1989-10-13 1999-10-01 스튜어트 엘.왓트 에리트로포이에틴 유사체와 그를 포함하는 제약학적 조성물
US5856298A (en) 1989-10-13 1999-01-05 Amgen Inc. Erythropoietin isoforms
US7217689B1 (en) 1989-10-13 2007-05-15 Amgen Inc. Glycosylation analogs of erythropoietin
IL192290A0 (en) 1993-08-17 2008-12-29 Kirin Amgen Inc Erythropoietin analogs
US6562596B1 (en) 1993-10-06 2003-05-13 Amgen Inc. Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods
US5830851A (en) 1993-11-19 1998-11-03 Affymax Technologies N.V. Methods of administering peptides that bind to the erythropoietin receptor
US5773569A (en) 1993-11-19 1998-06-30 Affymax Technologies N.V. Compounds and peptides that bind to the erythropoietin receptor
US5582593A (en) 1994-07-21 1996-12-10 Hultman; Barry W. Ambulatory medication delivery system
US5885574A (en) 1994-07-26 1999-03-23 Amgen Inc. Antibodies which activate an erythropoietin receptor
ATE306930T1 (de) 1994-08-12 2005-11-15 Immunomedics Inc Für b-zell-lymphom und leukämiezellen spezifische immunkonjugate und humane antikörper
US5730723A (en) 1995-10-10 1998-03-24 Visionary Medical Products Corporation, Inc. Gas pressured needle-less injection device and method
US5686292A (en) 1995-06-02 1997-11-11 Genentech, Inc. Hepatocyte growth factor receptor antagonist antibodies and uses thereof
US5767078A (en) 1995-06-07 1998-06-16 Johnson; Dana L. Agonist peptide dimers
ZA9610374B (en) * 1995-12-11 1997-06-23 Elan Med Tech Cartridge-based drug delivery device
US5830187A (en) 1995-12-22 1998-11-03 Science Incorporated Fluid delivery device with conformable ullage and fill assembly
US5879143A (en) 1996-04-26 1999-03-09 Sims Deltec, Inc. Reservoir enclosure adaptors and methods
US6355019B1 (en) 1996-12-18 2002-03-12 Science Incorporated Variable rate infusion apparatus with indicator and adjustable rate control
US20010039397A1 (en) 1996-12-18 2001-11-08 Kriesell Marshall S. Fluid delivery apparatus with flow indicator and vial fill
US6176845B1 (en) 1996-12-18 2001-01-23 Science Incorporated Fluid delivery apparatus with flow indicator and vial fill
US6183441B1 (en) 1996-12-18 2001-02-06 Science Incorporated Variable rate infusion apparatus with indicator and adjustable rate control
JPH1121116A (ja) 1997-06-30 1999-01-26 Nippon Steel Corp 窒化ホウ素で被覆された炭素質粉末および炭素質繊維
CA2296770A1 (en) 1997-07-14 1999-01-28 Bolder Biotechnology, Inc. Derivatives of growth hormone and related proteins
US6753165B1 (en) 1999-01-14 2004-06-22 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
PT986644E (pt) 1997-07-23 2007-01-31 Roche Diagnostics Gmbh Preparação de eritropoietina por activação genética endógena com promotores virais
US6030086A (en) 1998-03-02 2000-02-29 Becton, Dickinson And Company Flash tube reflector with arc guide
US6595956B1 (en) 1998-03-23 2003-07-22 Joseph Gross Drug delivery device
US6310078B1 (en) 1998-04-20 2001-10-30 Ortho-Mcneil Pharmaceutical, Inc. Substituted amino acids as erythropoietin mimetics
US20050181482A1 (en) 2004-02-12 2005-08-18 Meade Harry M. Method for the production of an erythropoietin analog-human IgG fusion proteins in transgenic mammal milk
US6548653B1 (en) 1998-06-15 2003-04-15 Genzyme Transgenics Corporation Erythropoietin analog-human serum albumin fusion
EP1124961B9 (en) 1998-10-23 2010-07-21 Kirin-Amgen Inc. Thrombopoietic compounds
HK1040944B (en) 1998-10-23 2007-09-07 Amgen Inc. Methods and compositions for the prevention and treatment of anemia
US7766873B2 (en) 1998-10-29 2010-08-03 Medtronic Minimed, Inc. Method and apparatus for detecting occlusions in an ambulatory infusion pump
US7621893B2 (en) 1998-10-29 2009-11-24 Medtronic Minimed, Inc. Methods and apparatuses for detecting occlusions in an ambulatory infusion pump
IL143266A0 (en) 1998-11-27 2002-04-21 Darwin Discovery Ltd Transforming growth factor-beta binding proteins and pharmaceutical compositions for increasing bone mineral content utilizing the same
EP1006184A1 (en) 1998-12-03 2000-06-07 F. Hoffmann-La Roche Ag IGF-1 receptor interacting proteins (IIPs) genes coding therefor and uses thereof
EP1169352A4 (en) 1999-04-14 2005-05-04 Smithkline Beecham Corp ANTIBODY AGAINST THE ERYTHROPOIETIN RECEPTOR
US7297680B2 (en) 1999-04-15 2007-11-20 Crucell Holland B.V. Compositions of erythropoietin isoforms comprising Lewis-X structures and high sialic acid content
CZ299516B6 (cs) 1999-07-02 2008-08-20 F. Hoffmann-La Roche Ag Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem
WO2001031007A2 (en) 1999-10-22 2001-05-03 Millennium Pharmaceuticals, Inc. Nucleic acid molecules derived from rat brain and programmed cell death models
US20050202538A1 (en) 1999-11-12 2005-09-15 Merck Patent Gmbh Fc-erythropoietin fusion protein with improved pharmacokinetics
AU2154401A (en) 1999-11-12 2001-05-30 Merck Patent Gmbh Erythropoietin forms with improved properties
BRPI0107736B8 (pt) 2000-01-21 2021-05-25 Biovex Ltd cepa hsv1 js1, composição farmacêutica, e, uso de uma cepa hsv1 js1
US6810290B2 (en) 2000-01-21 2004-10-26 Medtronic Minimed, Inc. Ambulatory medical apparatus with hand held communication device
AUPQ599700A0 (en) 2000-03-03 2000-03-23 Super Internet Site System Pty Ltd On-line geographical directory
US6586398B1 (en) 2000-04-07 2003-07-01 Amgen, Inc. Chemically modified novel erythropoietin stimulating protein compositions and methods
AU5551601A (en) 2000-04-21 2001-11-07 Amgen Inc Methods and compositions for the prevention and treatment of anemia
US6756480B2 (en) 2000-04-27 2004-06-29 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
US7078376B1 (en) 2000-08-11 2006-07-18 Baxter Healthcare S.A. Therapeutic methods for treating subjects with a recombinant erythropoietin having high activity and reduced side effects
MXPA03001469A (es) 2000-09-08 2004-12-13 Gryphon Therapeutics Inc Proteinas sinteticas estimulantes de la eritropoyesis.
DK1335764T3 (da) 2000-09-08 2007-10-01 Insulet Corp Apparat og system til patientinfusion
US7271689B1 (en) 2000-11-22 2007-09-18 Fonar Corporation Magnet structure
EP1345628B1 (en) 2000-12-20 2011-04-13 F. Hoffmann-La Roche AG Conjugates of erythropoietin (epo) with polyethylene glycol (peg)
GEP20084484B (en) 2001-01-05 2008-09-25 Pfizer Antibodies to insulin-like growth factor i receptor
CA2443373A1 (en) 2001-04-04 2002-10-31 Genodyssee New polynucleotides and polypeptides of the erythropoietin gene
US20040035491A1 (en) 2002-08-26 2004-02-26 Penjet Corporation Method and apparatus for needle-less injection with a degassed fluid
EP1921088B1 (en) 2001-05-11 2014-10-08 Amgen Inc. Peptides and related molecules that bind to tall-1
US20120209197A1 (en) 2002-01-04 2012-08-16 Lanigan Richard J Infusion pump assembly
US8034026B2 (en) 2001-05-18 2011-10-11 Deka Products Limited Partnership Infusion pump assembly
TR201809008T4 (tr) 2001-06-26 2018-07-23 Amgen Fremont Inc Opgl ye karşi antikorlar.
US6900292B2 (en) 2001-08-17 2005-05-31 Lee-Hwei K. Sun Fc fusion proteins of human erythropoietin with increased biological activities
US7247304B2 (en) 2001-08-23 2007-07-24 Genmab A/S Methods of treating using anti-IL-15 antibodies
EP1425389B1 (en) 2001-08-23 2011-11-02 Genmab A/S Human antibodies specific for interleukin 15 (il-15)
US6930086B2 (en) 2001-09-25 2005-08-16 Hoffmann-La Roche Inc. Diglycosylated erythropoietin
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7138370B2 (en) 2001-10-11 2006-11-21 Amgen Inc. Specific binding agents of human angiopoietin-2
US7521053B2 (en) 2001-10-11 2009-04-21 Amgen Inc. Angiopoietin-2 specific binding agents
US7429258B2 (en) 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US7204823B2 (en) 2001-12-19 2007-04-17 Medtronic Minimed, Inc. Medication delivery system and monitor
WO2003055526A2 (en) 2001-12-21 2003-07-10 Maxygen Aps Erythropoietin conjugates
AU2003216748B2 (en) 2002-01-18 2009-07-16 Pierre Fabre Medicament Novel anti-IGF-IR antibodies and uses thereof
US7241444B2 (en) 2002-01-18 2007-07-10 Pierre Fabre Medicament Anti-IGF-IR antibodies and uses thereof
GB0202252D0 (en) 2002-01-31 2002-03-20 Oxford Biomedica Ltd Anemia
EP1470232A1 (en) 2002-01-31 2004-10-27 Oxford Biomedica (UK) Limited Physiologically regulated erythropoietin-expressing vector for the treatment of anaemia
AU2003208305A1 (en) 2002-02-18 2003-09-04 Danfoss A/S Device for administering of medication in fluid form
US20050027264A1 (en) 2002-02-28 2005-02-03 Fleury Michael T. Huber needle with anti-rebound safety mechanism
US6878136B2 (en) 2002-02-28 2005-04-12 Medical Product Specialists Huber needle with anti-rebound safety mechanism
US6918894B2 (en) 2002-02-28 2005-07-19 Medical Product Specialists Huber needle with anti-rebound safety mechanism
US7033338B2 (en) 2002-02-28 2006-04-25 Smiths Medical Md, Inc. Cartridge and rod for axially loading medication pump
EP1492878B1 (en) 2002-03-26 2007-05-30 Lek Pharmaceutical and Chemical Co. D.D. Process for the preparation of a desired erythropoietin glyco-isoform profile
WO2003084477A2 (en) 2002-03-29 2003-10-16 Centocor, Inc. Mammalian cdr mimetibodies, compositions, methods and uses
DE60328092D1 (de) 2002-03-29 2009-08-06 Kumiai Chemical Industry Co Acetolactatsynthase codierende gene
CA2485365A1 (en) 2002-05-13 2003-11-20 Modigenetech Ltd. Ctp-extended erythropoietin
MXPA04011624A (es) 2002-05-24 2005-03-07 Schering Corp Anticuerpo neutralizante humano anti-igfr.
US8034904B2 (en) 2002-06-14 2011-10-11 Immunogen Inc. Anti-IGF-I receptor antibody
US7538195B2 (en) 2002-06-14 2009-05-26 Immunogen Inc. Anti-IGF-I receptor antibody
US7241733B2 (en) 2002-06-28 2007-07-10 Centocor, Inc. Mammalian EPO mimetic CH1 deleted mimetibodies, compositions, methods and uses
JP2006504406A (ja) 2002-06-28 2006-02-09 セントカー・インコーポレーテツド 哺乳動物のｃｈ１欠失ミメティボディ、組成物、方法および使用
WO2004009627A1 (en) 2002-07-19 2004-01-29 Cangene Corporation Pegylated erythropoietic compounds
WO2004018667A1 (ja) 2002-08-26 2004-03-04 Kirin Beer Kabushiki Kaisha ペプチド及びこれを含む医薬
JP4317817B2 (ja) 2002-09-06 2009-08-19 アムジェン インコーポレイテッド 治療用ヒト抗ｉｌ−１ｒ１モノクローナル抗体
WO2005025606A1 (en) 2003-09-09 2005-03-24 Warren Pharmaceuticals, Inc. Long acting erythropoietins that maintain tissue protective activity of endogenous erythropoietin
CA2496317C (en) 2002-09-11 2014-02-18 Fresenius Kabi Deutschland Gmbh Method of producing hydroxyalkyl starch derivatives
CN1723053A (zh) 2002-09-12 2006-01-18 儿童医院医疗中心 无痛药物注射的方法和设备
US6919426B2 (en) 2002-09-19 2005-07-19 Amgen Inc. Peptides and related molecules that modulate nerve growth factor activity
US20040071694A1 (en) 2002-10-14 2004-04-15 Devries Peter J. Erythropoietin receptor binding antibodies
US7396913B2 (en) 2002-10-14 2008-07-08 Abbott Laboratories Erythropoietin receptor binding antibodies
TWI320716B (en) 2002-10-14 2010-02-21 Abbott Lab Erythropoietin receptor binding antibodies
US20040091961A1 (en) 2002-11-08 2004-05-13 Evans Glen A. Enhanced variants of erythropoietin and methods of use
EA009056B1 (ru) 2002-12-20 2007-10-26 Амген, Инк. Связывающие агенты, ингибирующие миостатин
EP1603948A1 (en) 2003-03-14 2005-12-14 Pharmacia Corporation Antibodies to igf-i receptor for the treatment of cancers
JP4473257B2 (ja) 2003-04-02 2010-06-02 エフ．ホフマン−ラ ロシュ アーゲー インスリン様成長因子ｉ受容体に対する抗体及びその使用
US7220410B2 (en) 2003-04-18 2007-05-22 Galaxy Biotech, Llc Monoclonal antibodies to hepatocyte growth factor
CA2524305C (en) 2003-05-01 2015-12-08 Imclone Systems Incorporated Fully human antibodies directed against the human insulin-like growth factor-1 receptor
TWI353991B (en) 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
AU2004238869B2 (en) 2003-05-12 2009-06-25 Affymax, Inc. Novel poly(ethylene glycol) modified compounds and uses thereof
PT1625156E (pt) 2003-05-12 2013-01-09 Affymax Inc Novos péptidos que se fixam ao receptor da eritropoietina
CN100441595C (zh) 2003-05-12 2008-12-10 阿费麦克斯公司 结合红细胞生成素受体的新肽
US7074755B2 (en) 2003-05-17 2006-07-11 Centocor, Inc. Erythropoietin conjugate compounds with extended half-lives
US6995245B2 (en) 2003-05-30 2006-02-07 Centocor, Inc. Formation of novel erythropoietin conjugates using transglutaminase
DE10325106A1 (de) 2003-06-03 2004-12-30 Disetronic Licensing Ag Vorrichtung und Verfahren zur Erkennung eines Benutzers eines medizinischen Geräts
WO2005001136A1 (en) 2003-06-04 2005-01-06 Irm Llc Methods and compositions for modulating erythropoietin expression
WO2005000384A1 (en) 2003-06-05 2005-01-06 University Of Florida Auto-injection devices and methods for intramuscular administration of medications
EP1641516A4 (en) 2003-06-09 2010-03-03 Nipro Diabetes Systems Inc COUPLING SYSTEM FOR INFUSION PUMP
AR046071A1 (es) 2003-07-10 2005-11-23 Hoffmann La Roche Anticuerpos contra el receptor i del factor de crecimiento de tipo insulinico y los usos de los mismos
TWI382031B (zh) 2003-07-15 2013-01-11 Amgen Inc 作為選擇性神經生長因子（ｎｇｆ）通道抑制劑之人類抗-ｎｇｆ中和抗體
CN103880955A (zh) 2003-07-18 2014-06-25 安姆根有限公司 肝细胞生长因子的特异性结合物
US20050019914A1 (en) 2003-07-24 2005-01-27 Aventis Pharma Deutschland Gmbh Perfusion process for producing erythropoietin
GB0317511D0 (en) 2003-07-25 2003-08-27 Biovex Ltd Viral vectors
EP1502613A1 (en) * 2003-08-01 2005-02-02 Novo Nordisk A/S Needle device with retraction means
EP1654018A4 (en) 2003-08-12 2010-11-17 Becton Dickinson Co PLASTER-INFUSION DEVICE
JP2007512001A (ja) 2003-08-28 2007-05-17 バイオレクシス ファーマシューティカル コーポレイション Ｅｐｏミメティックペプチドおよび融合タンパク質
WO2005081687A2 (en) 2003-09-30 2005-09-09 Centocor, Inc. Human hinge core mimetibodies, compositions, methods and uses
UA89481C2 (uk) 2003-09-30 2010-02-10 Центокор, Инк. Еритропоетинові міметичні шарнірно-серцевинні міметитіла людини, композиції, способи та застосування
TWI356064B (en) 2003-11-07 2012-01-11 Immunex Corp Antibodies that bind interleukin-4 receptor
AR046639A1 (es) 2003-11-21 2005-12-14 Schering Corp Combinaciones terapeuticas de anticuerpo anti- igfr1
NZ547168A (en) 2003-11-24 2010-05-28 Biogenerix Ag Glycopegylated erythropoietin
US8633157B2 (en) 2003-11-24 2014-01-21 Novo Nordisk A/S Glycopegylated erythropoietin
WO2005058967A2 (en) 2003-12-16 2005-06-30 Pierre Fabre Medicament Novel anti-insulin/igf-i hybrid receptor or anti-insulin/igf-i hybrid receptor and igf-ir antibodies and uses thereof
EP1548031A1 (en) 2003-12-22 2005-06-29 Dubai Genetics FZ-LLC Nature-identical erythropoietin
AU2004311796A1 (en) 2003-12-31 2005-07-21 Centocor, Inc. Novel recombinant proteins with N-terminal free thiol
BRPI0417916A (pt) 2003-12-31 2007-04-10 Merck Patent Gmbh proteìna de fusão de fc-eritropoietina com farmacocinética melhorada
US7423139B2 (en) 2004-01-20 2008-09-09 Insight Biopharmaceuticals Ltd. High level expression of recombinant human erythropoietin having a modified 5′-UTR
US20050187158A1 (en) 2004-01-22 2005-08-25 Ranby Mats G. Pharmaceutical composition
WO2005084711A1 (en) 2004-03-02 2005-09-15 Chengdu Institute Of Biological Products A pegylated recombinant erythropoietin that has in vivo activity
AR048918A1 (es) 2004-03-11 2006-06-14 Fresenius Kabi De Gmbh Conjugados de almidon de hidroxietilo y eritropoyetina
US20050227289A1 (en) 2004-04-09 2005-10-13 Reilly Edward B Antibodies to erythropoietin receptor and uses thereof
US20080194475A1 (en) 2004-04-23 2008-08-14 Andrew Buchanan Erythropoietin Protein Variants
US7220245B2 (en) 2004-05-26 2007-05-22 Kriesel Marshall S Infusion apparatus
EP1781697B1 (en) 2004-07-07 2009-04-22 H.Lundbeck A/S Novel carbamylated epo and method for its production
FR2873699B1 (fr) 2004-07-29 2009-08-21 Pierre Fabre Medicament Sa Nouveaux anticorps anti igf ir rt leurs utilisations
WO2006029094A2 (en) 2004-09-02 2006-03-16 Xencor, Inc. Erythropoietin derivatives with altered immunogenicity
EP1805563B1 (en) 2004-10-28 2015-12-09 Hewlett-Packard Development Company, L.P. Adhesive primer coating for printing
CA2586915A1 (en) 2004-11-10 2006-05-18 Aplagen Gmbh Molecules which promote hematopoiesis
MY146381A (en) 2004-12-22 2012-08-15 Amgen Inc Compositions and methods relating relating to anti-igf-1 receptor antibodies
US7906625B2 (en) 2005-01-24 2011-03-15 Amgen Inc. Humanized anti-amyloid antibody
PL2058020T3 (pl) * 2005-02-01 2013-03-29 Kaleo Inc Urządzenie do podawania leków
WO2006086723A2 (en) 2005-02-11 2006-08-17 Stryker Corporation Reprogrammable fluid delivery system and method of use
US7618393B2 (en) 2005-05-03 2009-11-17 Pharmajet, Inc. Needle-less injector and method of fluid delivery
US7592429B2 (en) 2005-05-03 2009-09-22 Ucb Sa Sclerostin-binding antibody
PL2100614T3 (pl) 2005-06-17 2014-02-28 Imclone Llc Przeciwciała przeciwko PDGFR alfa do zastosowania w leczeniu guzów nowotworowych
JP2008543500A (ja) 2005-06-21 2008-12-04 イーライ リリー アンド カンパニー 医薬品注射用の器具及び方法
WO2007000328A1 (en) 2005-06-27 2007-01-04 Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa Antibodies that bind to an epitope on insulin-like growth factor 1 receptor and uses thereof
EP2388276A3 (en) 2005-07-18 2013-11-27 Amgen, Inc Human anti-B7RP1 neutralizing antibodies
FR2888850B1 (fr) 2005-07-22 2013-01-11 Pf Medicament Nouveaux anticorps anti-igf-ir et leurs applications
US20070038181A1 (en) 2005-08-09 2007-02-15 Alexander Melamud Method, system and device for delivering a substance to tissue
PE20071101A1 (es) 2005-08-31 2007-12-21 Amgen Inc Polipeptidos y anticuerpos
US20070093753A1 (en) 2005-09-19 2007-04-26 Lifescan, Inc. Malfunction Detection Via Pressure Pulsation
DE102005052502A1 (de) 2005-11-03 2007-05-16 Tecpharma Licensing Ag Autoinjektor-Aktivierung Auslöseelement
US20150057615A1 (en) 2005-11-08 2015-02-26 Asante Solutions Infusion Pump System
US8088096B2 (en) 2006-01-31 2012-01-03 Ares Trading S.A. Injection device with a capacitive proximity sensor
US9839743B2 (en) 2006-02-09 2017-12-12 Deka Products Limited Partnership Apparatus, system and method for fluid delivery
DE602007013723D1 (de) 2006-02-09 2011-05-19 Deka Products Lp Systeme zur abgabe von flüssigkeiten in patch-grösse
EP1998830A2 (en) 2006-03-20 2008-12-10 Novo Nordisk A/S Determination of position of injection needle
TWI395754B (zh) 2006-04-24 2013-05-11 Amgen Inc 人類化之ｃ-ｋｉｔ抗體
US20070270744A1 (en) 2006-05-17 2007-11-22 Bruno Dacquay Limited Reuse Assembly For Ophthalmic Injection Device
US7851438B2 (en) 2006-05-19 2010-12-14 GlycoFi, Incorporated Erythropoietin compositions
US20070282269A1 (en) 2006-05-31 2007-12-06 Seattle Medical Technologies Cannula delivery apparatus and method for a disposable infusion device
US9308325B2 (en) 2006-06-19 2016-04-12 Corium International, Inc. Methods, devices, and kits for microjet drug delivery
CL2007002567A1 (es) 2006-09-08 2008-02-01 Amgen Inc Proteinas aisladas de enlace a activina a humana.
WO2008038241A2 (en) 2006-09-29 2008-04-03 Koninklijke Philips Electronics N.V. Electrically activated gel array for transdermal drug delivery
US20080234625A1 (en) 2006-10-16 2008-09-25 Bruno Dacquay Fuse Assembly For Single Use Medical Device
US20110077614A1 (en) 2006-10-19 2011-03-31 Ofer Shay Device and method for patient activated bolus administration
EP2106261A4 (en) 2006-11-07 2010-05-26 Merck Sharp & Dohme ANTAGONISTS OF PCSK9
WO2008057457A2 (en) 2006-11-07 2008-05-15 Merck & Co., Inc. Antagonists of pcsk9
CA2667869A1 (en) 2006-11-07 2008-05-15 Merck & Co., Inc. Antagonists of pcsk9
US20100041102A1 (en) 2006-11-07 2010-02-18 Ayesha Sitlani Antagonists of pcsk9
US7946985B2 (en) 2006-12-29 2011-05-24 Medtronic Minimed, Inc. Method and system for providing sensor redundancy
EP2136863A2 (en) 2007-03-19 2009-12-30 Insuline Medical Ltd. Device for drug delivery and associated connections thereto
EP3461517A1 (de) * 2007-03-22 2019-04-03 Tecpharma Licensing AG Injektionsvorrichtung mit signalisierungseinheit
CA2681428A1 (en) 2007-04-13 2008-10-23 Novartis Ag Molecules and methods for modulating proprotein convertase subtilisin/kexin type 9 (pcsk9)
JP5328767B2 (ja) * 2007-05-10 2013-10-30 メディックス−セット リミテッド 自己閉塞メカニズムを備えるインフュージョン・セットおよびシステム
US7794426B2 (en) 2007-05-21 2010-09-14 Asante Solutions, Inc. Infusion pump system with contamination-resistant features
US7981102B2 (en) 2007-05-21 2011-07-19 Asante Solutions, Inc. Removable controller for an infusion pump
CN103394143B (zh) 2007-07-20 2015-06-24 F·霍夫曼-拉罗氏股份公司 可手动操作的便携式输注设备
US8683381B2 (en) 2007-08-09 2014-03-25 Alfred E. Mann Foundation For Scientific Research Drug delivery safety system
US20090082730A1 (en) 2007-09-24 2009-03-26 Li Nguyen Needle injection assembly
US7771391B2 (en) 2007-09-28 2010-08-10 Calibra Medical, Inc. Disposable infusion device with snap action actuation
US8226606B2 (en) 2007-09-28 2012-07-24 Calibra Medical, Inc. Disposable infusion device with tactile dosage volume indicator
US20090099525A1 (en) 2007-10-11 2009-04-16 Animas Corporation Drug Delivery System with Breakaway Plunger Extractor
SG2013014352A (en) 2007-10-26 2014-09-26 Merck Sharp & Dohme Anti-pcsk9 and methods for treating lipid and cholesterol disorders
US7875022B2 (en) 2007-12-12 2011-01-25 Asante Solutions, Inc. Portable infusion pump and media player
US7976505B2 (en) 2007-12-19 2011-07-12 Calibra Medical, Inc. Disposable infusion device negative pressure filling apparatus and method
US10188787B2 (en) 2007-12-31 2019-01-29 Deka Products Limited Partnership Apparatus, system and method for fluid delivery
US20090177142A1 (en) 2008-01-09 2009-07-09 Smiths Medical Md, Inc Insulin pump with add-on modules
AR070316A1 (es) 2008-02-07 2010-03-31 Merck & Co Inc Antagonistas de pcsk9 (proproteina subtilisina-kexina tipo 9)
AR070315A1 (es) 2008-02-07 2010-03-31 Merck & Co Inc Anticuerpos 1b20 antagonistas de pcsk9
US8540673B2 (en) 2008-03-18 2013-09-24 Calibra Medical, Inc. Disposable infusion device with actuation lock-out
US7976500B2 (en) 2008-06-26 2011-07-12 Calibra Medical, Inc. Disposable infusion device with redundant valved safety
US7927306B2 (en) 2008-06-26 2011-04-19 Calibra Medical, Inc. Disposable infusion device with prime indicator
US8231577B2 (en) 2008-06-26 2012-07-31 Calibra Medical, Inc. Disposable infusion device with automatically releasable cannula driver
GB0814747D0 (en) * 2008-08-13 2008-09-17 Owen Mumford Ltd Autoinjection devices
WO2010029054A1 (en) * 2008-09-10 2010-03-18 F. Hoffmann-La Roche Ag Delivery device for use with a therapeutic drug
TWI445716B (zh) 2008-09-12 2014-07-21 Rinat Neuroscience Corp Ｐｃｓｋ９拮抗劑類
US8262616B2 (en) 2008-10-10 2012-09-11 Deka Products Limited Partnership Infusion pump assembly
US8016789B2 (en) 2008-10-10 2011-09-13 Deka Products Limited Partnership Pump assembly with a removable cover assembly
US8223028B2 (en) 2008-10-10 2012-07-17 Deka Products Limited Partnership Occlusion detection system and method
US20100121274A1 (en) 2008-11-12 2010-05-13 Baxter International Inc. Prefillable constant pressure ambulatory infusion pump
JO3672B1 (ar) 2008-12-15 2020-08-27 Regeneron Pharma أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9).
US9370621B2 (en) 2008-12-16 2016-06-21 Medtronic Minimed, Inc. Needle insertion systems and methods
JO3382B1 (ar) 2008-12-23 2019-03-13 Amgen Inc أجسام مضادة ترتبط مع مستقبل cgrp بشري
US8548623B2 (en) 2009-03-18 2013-10-01 Acelrx Pharmaceuticals, Inc. Storage and dispensing devices for administration of oral transmucosal dosage forms
US7976493B2 (en) 2009-05-05 2011-07-12 Calibra Medical, Inc. Disposable infusion device with resettable last dose lock-out
US8344847B2 (en) 2009-07-09 2013-01-01 Medtronic Minimed, Inc. Coordination of control commands in a medical device system having at least one therapy delivery device and at least one wireless controller device
US8882710B2 (en) 2009-09-02 2014-11-11 Medtronic Minimed, Inc. Insertion device systems and methods
US10071198B2 (en) 2012-11-02 2018-09-11 West Pharma. Servicees IL, Ltd. Adhesive structure for medical device
EP2480576A4 (en) 2009-09-25 2013-04-10 Merck Sharp & Dohme PCSK9 ANTAGONISTS
EP2301611B1 (en) 2009-09-25 2012-08-15 Letcat Aktiebolag Medical delivery device
CN104474606B (zh) 2009-10-13 2017-04-26 瓦莱里塔斯公司 流体输送装置
US7967773B2 (en) 2009-10-13 2011-06-28 Smiths Medical Asd, Inc. Two piece medication cassette closure apparatus and method
CA2777542A1 (en) 2009-10-30 2011-05-05 Merck Sharp & Dohme Corp. Ax213 and ax132 pcsk9 antagonists and variants
EP2493505A4 (en) 2009-10-30 2013-06-12 Merck Sharp & Dohme Ax1 and ax189 pcsk9 antagonists and variants
US8449504B2 (en) 2009-11-11 2013-05-28 Calibra Medical, Inc. Wearable infusion device and system
AR079336A1 (es) 2009-12-11 2012-01-18 Irm Llc Antagonistas de la pro-proteina convertasa-subtilisina/quexina tipo 9 (pcsk9)
EP2512579B1 (en) 2009-12-16 2016-11-30 Becton, Dickinson and Company Self-injection device
US20120323183A1 (en) 2009-12-16 2012-12-20 Bart Peterson Self-injection device
ES2862501T3 (es) 2009-12-16 2021-10-07 Becton Dickinson Co Dispositivo de autoinyección
CN102753213B (zh) 2009-12-16 2015-04-29 贝克顿·迪金森公司 自注射装置
US10195340B2 (en) 2009-12-16 2019-02-05 Becton, Dickinson And Company Self-injection device
WO2011082370A1 (en) 2009-12-31 2011-07-07 Abbott Diabetes Care Inc. Injection port device adapted for use with insulin pump
US8070723B2 (en) 2009-12-31 2011-12-06 Medtronic Minimed, Inc. Activity guard
WO2011091246A2 (en) * 2010-01-22 2011-07-28 Deka Products Limited Partnership Infusion pump apparatus, method and system
EP2536451B1 (en) 2010-02-18 2018-03-28 Sanofi-Aventis Deutschland GmbH Auto-injector with a torsion spring
KR20120120466A (ko) 2010-02-25 2012-11-01 라이프스캔 스코트랜드 리미티드 인슐린 투약에 대한 안전 경고를 갖는 분석물 검사 방법 및 시스템
SG183867A1 (en) 2010-03-11 2012-10-30 Rinat Neuroscience Corp ANTIBODIES WITH pH DEPENDENT ANTIGEN BINDING
RU2695703C2 (ru) 2010-04-21 2019-07-25 Эббви Байотекнолоджи Лтд. Носимое устройство для автоматической инъекции для управляемой подачи терапевтических агентов
US9737659B2 (en) 2010-05-12 2017-08-22 Bioq Pharma Incorporated Apparatus for dispensing medicinal fluids and method of making same
US8821454B2 (en) 2010-05-12 2014-09-02 Bioquiddity, Inc. Apparatus for dispensing medicinal fluids and method of making same
EP2575935B2 (en) * 2010-06-07 2023-08-23 Amgen Inc. Drug delivery device
WO2012032411A2 (en) 2010-09-07 2012-03-15 Tecpharma Licensing Ag Automatic injection device
US9216249B2 (en) 2010-09-24 2015-12-22 Perqflo, Llc Infusion pumps
US8915879B2 (en) 2010-09-24 2014-12-23 Perqflo, Llc Infusion pumps
US8430849B2 (en) 2010-09-24 2013-04-30 Perqflo, Llc Infusion pumps and plunger pusher position-responsive cartridge lock for infusion pumps
US9498573B2 (en) 2010-09-24 2016-11-22 Perqflo, Llc Infusion pumps
EP2438945A1 (en) 2010-10-08 2012-04-11 Sanofi-Aventis Deutschland GmbH Reusable engine for an auto-injector
WO2012054438A1 (en) 2010-10-22 2012-04-26 Schering Corporation Anti-pcsk9
US9211378B2 (en) 2010-10-22 2015-12-15 Cequr Sa Methods and systems for dosing a medicament
AU2011325247B2 (en) 2010-11-03 2015-01-22 Sanofi-Aventis Deutschland Gmbh Medicated module with interlock
US8905972B2 (en) 2010-11-20 2014-12-09 Perqflo, Llc Infusion pumps
GB201020475D0 (en) 2010-12-02 2011-01-19 Oval Medical Technologies Ltd Delivery mechanism for an autoinjector
MX2013007168A (es) 2010-12-22 2013-11-04 Genentech Inc Anticuerpo anti-pcsk9 y metodos de uso.
WO2012101252A2 (en) 2011-01-28 2012-08-02 Sanofi Human antibodies to pcsk9 for use in methods of treating particular groups of subjects
EA201391157A1 (ru) 2011-02-11 2014-02-28 АйАрЭм ЭлЭлСи Антагонисты pcsk9
MX345747B (es) * 2011-04-21 2017-02-14 Abbvie Inc Dispositivo de inyección automático portable.
WO2013016376A2 (en) 2011-07-25 2013-01-31 Preciflex Sa Fluid dispenser
EP2731641B1 (en) 2011-09-02 2021-09-29 UNL Holdings LLC Drive mechanism for drug delivery pumps with integrated status indication
WO2013030000A1 (en) 2011-09-02 2013-03-07 F. Hoffmann-La Roche Ag Dosing unit for an ambulatory infusion device
US9814832B2 (en) * 2011-09-02 2017-11-14 Unl Holdings Llc Drive mechanism for drug delivery pumps with integrated status indication
US9707335B2 (en) * 2011-09-02 2017-07-18 Unitract Syringe Pty Ltd Drive mechanism for drug delivery pumps with integrated status indication
WO2013029999A1 (en) 2011-09-02 2013-03-07 F. Hoffmann-La Roche Ag Dosing unit for an ambulatory infusion device
PL3412323T3 (pl) 2011-09-09 2021-06-28 Merck Patent Gmbh Autowstrzykiwacz do wstrzykiwania epinefryny
JP6424089B2 (ja) 2011-11-07 2018-11-14 イーライ リリー アンド カンパニー 人間工学的改善を施した注射器具
DE102011119000A1 (de) 2011-11-21 2013-05-23 Liebherr-Verzahntechnik Gmbh Verzahnmaschine und Verfahren zur Herstellung oder Bearbeitung von Verzahnungen
US10058655B2 (en) 2011-11-22 2018-08-28 Sanofi-Aventis Deutschland Gmbh Pen-type drug injection device with controller and time lock-out mechanism for its drive
US10052435B2 (en) 2012-01-31 2018-08-21 Precifiex SA Skin-attachable miniature drug injection device with remote activation capability and dry drug carrier within injection needle
US10335545B2 (en) 2012-01-31 2019-07-02 West Pharma. Services IL, Ltd. Time dependent drug delivery apparatus
EP2628494A1 (en) 2012-02-17 2013-08-21 Sensile Pat AG Liquid storage and delivery system
DK2819724T3 (da) 2012-02-27 2019-05-27 Hoffmann La Roche Fjederkraftsamling til forspænding eller aktivering af propper i sprøjter, patroner til injektionspenne og lignende
US9072827B2 (en) 2012-03-26 2015-07-07 Medimop Medical Projects Ltd. Fail safe point protector for needle safety flap
EP2836261B1 (en) 2012-04-13 2020-01-15 Becton, Dickinson and Company Infusion device with safety feature for preventing inadvertent activation
US9335910B2 (en) 2012-04-23 2016-05-10 Tandem Diabetes Care, Inc. System and method for reduction of inadvertent activation of medical device during manipulation
US9715327B2 (en) 2012-06-07 2017-07-25 Tandem Diabetes Care, Inc. Preventing inadvertent changes in ambulatory medical devices
EP2674179A1 (en) 2012-06-15 2013-12-18 Ares Trading S.A. Injection device
US8454557B1 (en) 2012-07-19 2013-06-04 Asante Solutions, Inc. Infusion pump system and method
EP2879741B1 (en) 2012-07-31 2021-04-28 Nipro Healthcare Systems, LLC Device and method for dispensing fluid from an infusion pump
WO2014025796A2 (en) 2012-08-06 2014-02-13 Minipumps, Llc. Piston pump devices
US9867929B2 (en) 2012-08-15 2018-01-16 Becton, Dickinson And Company Pump engine with metering system for dispensing liquid medication
US20140088555A1 (en) 2012-09-24 2014-03-27 Po-Ying Li Systems and Methods for Electrolysis Pump Control
US9782538B2 (en) 2012-09-27 2017-10-10 Becton, Dickinson And Company Angled inserter for drug infusion
EP2716317A1 (en) 2012-10-04 2014-04-09 Sanofi-Aventis Deutschland GmbH Medicament delivery device with trigger button
US9789250B2 (en) 2012-10-05 2017-10-17 Becton, Dickinson And Company Infusion set with safety device
GB201218913D0 (en) 2012-10-22 2012-12-05 Ucb Pharma Sa Auto-injector and drive unit therefor
JP6205701B2 (ja) 2012-10-22 2017-10-04 セイコーエプソン株式会社 流体注入装置
JP2014087449A (ja) 2012-10-30 2014-05-15 Seiko Epson Corp 液体輸送装置及びカテーテルの抜け判定方法
KR101745226B1 (ko) * 2012-12-21 2017-06-20 케어베이 유럽 리미티드 약물 전달 디바이스
GB2523512A (en) 2012-12-27 2015-08-26 Kaleo Inc Devices, systems and methods for locating and interacting with medicament delivery systems
DE202013000411U1 (de) 2013-01-16 2013-01-24 H & B Electronic Gmbh & Co. Kg Dauerinfusionsvorrichtung
CN109568719A (zh) 2013-01-25 2019-04-05 尤尼特拉克特注射器控股有限公司 用于输药泵的液体限制机构
WO2014116274A1 (en) 2013-01-25 2014-07-31 Unitract Syringe Pty Ltd Integrated sliding seal fluid pathway connection and drug containers for drug delivery pumps
DK2764881T3 (da) 2013-02-06 2019-10-28 Medirio Sa System til medicinsk behandling
US9446186B2 (en) 2013-03-01 2016-09-20 Bigfoot Biomedical, Inc. Operating an infusion pump system
US20140276423A1 (en) 2013-03-14 2014-09-18 Tandem Diabetes Care, Inc. Infusion system and methods
US9889252B2 (en) 2013-06-14 2018-02-13 Medtronic, Inc. Infusion device assembly
US20150005703A1 (en) 2013-06-28 2015-01-01 Animas Corporation Drug infusion device with safety interlock
DK2865325T3 (en) 2013-10-23 2018-02-19 Hoffmann La Roche STANDING ON THE SKIN OF INFUSION PUMP OR CONTINUOUS BLOOD SUGAR MONITOR WITH OPTICAL INDICATION ORGANIZATION
US10130755B2 (en) 2013-12-31 2018-11-20 Abbvie Inc. Devices and methods for delivering a beneficial agent to a user
US10195342B2 (en) 2014-04-24 2019-02-05 Becton, Dickinson And Company Cannula deployment mechanism
EP3848072A1 (en) 2014-12-19 2021-07-14 Amgen Inc. Drug delivery device with proximity sensor

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