US20020081679A1
(en)
*
|
1999-10-22 |
2002-06-27 |
Millennium Pharmaceuticals, Inc. |
NARC8 programmed cell-death-associated molecules and uses thereof
|
AU2001241461A1
(en)
*
|
2000-02-07 |
2001-08-14 |
Millennium Pharmaceuticals, Inc. |
Narc-1, novel subtilase-like homologs
|
US20030165863A1
(en)
*
|
2001-01-16 |
2003-09-04 |
Millennium Pharmaceuticals, Inc. |
NARC10 and NARC16, programmed cell death-associated molecules and uses thereof
|
US7572618B2
(en)
|
2006-06-30 |
2009-08-11 |
Bristol-Myers Squibb Company |
Polynucleotides encoding novel PCSK9 variants
|
CN101636179B
(en)
|
2006-11-07 |
2012-10-10 |
默沙东公司 |
Antagonists of pcsk9
|
WO2008109871A2
(en)
*
|
2007-03-08 |
2008-09-12 |
Irm Llc |
Crystal structure of proprotein convertase 9 (pcsk9) and uses thereof
|
WO2008118386A2
(en)
|
2007-03-27 |
2008-10-02 |
Merck & Co., Inc. |
Method for detecting autoprocessed, secreted pcsk9
|
JOP20080381B1
(en)
|
2007-08-23 |
2023-03-28 |
Amgen Inc |
Antigen Binding Proteins to Proprotein Convertase subtillisin Kexin type 9 (pcsk9)
|
AR070316A1
(en)
|
2008-02-07 |
2010-03-31 |
Merck & Co Inc |
PCSK9 ANTAGONISTS (SUBTILISINE-KEXINA TYPE 9 PROPROTEIN)
|
AR070315A1
(en)
|
2008-02-07 |
2010-03-31 |
Merck & Co Inc |
ANTIBODIES 1B20 ANTAGONISTS OF PCSK9
|
WO2010068526A1
(en)
|
2008-12-12 |
2010-06-17 |
Merck Sharp & Dohme Corp. |
Pcsk9 immunoassay
|
EP2493505A4
(en)
|
2009-10-30 |
2013-06-12 |
Merck Sharp & Dohme |
Ax1 and ax189 pcsk9 antagonists and variants
|
JP2013509194A
(en)
|
2009-10-30 |
2013-03-14 |
メルク・シャープ・エンド・ドーム・コーポレイション |
AX213 and AX132PCSK9 antagonists and variants
|
AR087715A1
(en)
|
2011-09-16 |
2014-04-09 |
Lilly Co Eli |
ANTI PCSK9 ANTIBODIES AND USES OF THE SAME
|
EP2922590B1
(en)
|
2012-11-21 |
2020-02-05 |
Amgen Inc. |
Drug delivery device
|
TWI580451B
(en)
|
2013-03-15 |
2017-05-01 |
安美基公司 |
Cassette for an injector and method of using an autoinjector apparatus having an autoinjector and a cassette
|
EP3593839A1
(en)
|
2013-03-15 |
2020-01-15 |
Amgen Inc. |
Drug cassette
|
LT2976117T
(en)
|
2013-03-22 |
2021-02-25 |
Amgen Inc. |
Injector and method of assembly
|
AU2014340171B2
(en)
|
2013-10-24 |
2019-05-30 |
Amgen Inc. |
Injector and method of assembly
|
WO2015061389A1
(en)
|
2013-10-24 |
2015-04-30 |
Amgen Inc. |
Drug delivery system with temperature-sensitive control
|
US9023359B1
(en)
|
2014-07-15 |
2015-05-05 |
Kymab Limited |
Targeting rare human PCSK9 variants for cholesterol treatment
|
US8883157B1
(en)
|
2013-12-17 |
2014-11-11 |
Kymab Limited |
Targeting rare human PCSK9 variants for cholesterol treatment
|
US8945560B1
(en)
|
2014-07-15 |
2015-02-03 |
Kymab Limited |
Method of treating rheumatoid arthritis using antibody to IL6R
|
US9045548B1
(en)
|
2014-07-15 |
2015-06-02 |
Kymab Limited |
Precision Medicine by targeting rare human PCSK9 variants for cholesterol treatment
|
US8986691B1
(en)
|
2014-07-15 |
2015-03-24 |
Kymab Limited |
Method of treating atopic dermatitis or asthma using antibody to IL4RA
|
US9017678B1
(en)
|
2014-07-15 |
2015-04-28 |
Kymab Limited |
Method of treating rheumatoid arthritis using antibody to IL6R
|
US8986694B1
(en)
|
2014-07-15 |
2015-03-24 |
Kymab Limited |
Targeting human nav1.7 variants for treatment of pain
|
US9914769B2
(en)
|
2014-07-15 |
2018-03-13 |
Kymab Limited |
Precision medicine for cholesterol treatment
|
US9034332B1
(en)
|
2014-07-15 |
2015-05-19 |
Kymab Limited |
Precision medicine by targeting rare human PCSK9 variants for cholesterol treatment
|
US9067998B1
(en)
|
2014-07-15 |
2015-06-30 |
Kymab Limited |
Targeting PD-1 variants for treatment of cancer
|
US9051378B1
(en)
|
2014-07-15 |
2015-06-09 |
Kymab Limited |
Targeting rare human PCSK9 variants for cholesterol treatment
|
US8992927B1
(en)
|
2014-07-15 |
2015-03-31 |
Kymab Limited |
Targeting human NAV1.7 variants for treatment of pain
|
US8980273B1
(en)
|
2014-07-15 |
2015-03-17 |
Kymab Limited |
Method of treating atopic dermatitis or asthma using antibody to IL4RA
|
US9045545B1
(en)
|
2014-07-15 |
2015-06-02 |
Kymab Limited |
Precision medicine by targeting PD-L1 variants for treatment of cancer
|
WO2015119906A1
(en)
|
2014-02-05 |
2015-08-13 |
Amgen Inc. |
Drug delivery system with electromagnetic field generator
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
CA3193070A1
(en)
|
2014-05-07 |
2015-11-12 |
Amgen Inc. |
Autoinjector with shock reducing elements
|
JP6817074B2
(en)
|
2014-06-03 |
2021-01-20 |
アムジエン・インコーポレーテツド |
Controllable drug delivery system and usage
|
US9139648B1
(en)
|
2014-07-15 |
2015-09-22 |
Kymab Limited |
Precision medicine by targeting human NAV1.9 variants for treatment of pain
|
US9150660B1
(en)
|
2014-07-15 |
2015-10-06 |
Kymab Limited |
Precision Medicine by targeting human NAV1.8 variants for treatment of pain
|
MX2021014323A
(en)
|
2014-10-14 |
2023-02-02 |
Amgen Inc |
Drug injection device with visual and audio indicators.
|
US11357916B2
(en)
|
2014-12-19 |
2022-06-14 |
Amgen Inc. |
Drug delivery device with live button or user interface field
|
EP3233163B1
(en)
|
2014-12-19 |
2021-10-13 |
Amgen Inc. |
Drug delivery device with proximity sensor
|
CA3069716C
(en)
|
2015-02-17 |
2021-11-09 |
Amgen Inc. |
Drug delivery device with vacuum assisted securement and/or feedback
|
EP3981450A1
(en)
|
2015-02-27 |
2022-04-13 |
Amgen, Inc |
Drug delivery device having a needle guard mechanism with a tunable threshold of resistance to needle guard movement
|
WO2017039786A1
(en)
|
2015-09-02 |
2017-03-09 |
Amgen Inc. |
Syringe assembly adapter for a syringe
|
JP7082568B2
(en)
|
2015-12-09 |
2022-06-08 |
アムジエン・インコーポレーテツド |
Automatic syringe with signal transduction cap
|
WO2017120178A1
(en)
|
2016-01-06 |
2017-07-13 |
Amgen Inc. |
Auto-injector with signaling electronics
|
EP3721922B1
(en)
|
2016-03-15 |
2022-05-04 |
Amgen Inc. |
Reducing probability of glass breakage in drug delivery devices
|
US11541168B2
(en)
|
2016-04-29 |
2023-01-03 |
Amgen Inc. |
Drug delivery device with messaging label
|
US11389588B2
(en)
|
2016-05-02 |
2022-07-19 |
Amgen Inc. |
Syringe adapter and guide for filling an on-body injector
|
CA3018426A1
(en)
|
2016-05-13 |
2017-11-16 |
Amgen Inc. |
Vial sleeve assembly
|
WO2017200989A1
(en)
|
2016-05-16 |
2017-11-23 |
Amgen Inc. |
Data encryption in medical devices with limited computational capability
|
EP3465124A1
(en)
|
2016-06-03 |
2019-04-10 |
Amgen Inc. |
Impact testing apparatuses and methods for drug delivery devices
|
EP3478342A1
(en)
|
2016-07-01 |
2019-05-08 |
Amgen Inc. |
Drug delivery device having minimized risk of component fracture upon impact events
|
WO2018034784A1
(en)
|
2016-08-17 |
2018-02-22 |
Amgen Inc. |
Drug delivery device with placement detection
|
US20200261643A1
(en)
|
2016-10-25 |
2020-08-20 |
Amgen Inc. |
On-body injector
|
WO2018083248A1
(en)
|
2016-11-03 |
2018-05-11 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses & methods
|
CN110352242A
(en)
|
2016-12-23 |
2019-10-18 |
哈佛大学的校长及成员们 |
The gene editing of PCSK9
|
AU2018210301A1
(en)
|
2017-01-17 |
2019-08-01 |
Amgen Inc. |
Injection devices and related methods of use and assembly
|
EP3582829A1
(en)
|
2017-02-17 |
2019-12-25 |
Amgen Inc. |
Insertion mechanism for drug delivery device
|
MX2019009625A
(en)
|
2017-02-17 |
2019-10-09 |
Amgen Inc |
Drug delivery device with sterile fluid flowpath and related method of assembly.
|
CA3050927A1
(en)
|
2017-03-06 |
2018-09-13 |
Brian Stonecipher |
Drug delivery device with activation prevention feature
|
CA3052482A1
(en)
|
2017-03-07 |
2018-09-13 |
Amgen Inc. |
Needle insertion by overpressure
|
IL303449B1
(en)
|
2017-03-09 |
2024-04-01 |
Amgen Inc |
Insertion mechanism for drug delivery device
|
CN114588404A
(en)
|
2017-03-28 |
2022-06-07 |
美国安进公司 |
Plunger rod and syringe assembly systems and methods
|
AU2018282077B2
(en)
|
2017-06-08 |
2023-11-23 |
Amgen Inc. |
Torque driven drug delivery device
|
AU2018280054B2
(en)
|
2017-06-08 |
2023-07-13 |
Amgen Inc. |
Syringe assembly for a drug delivery device and method of assembly
|
AU2018288604B2
(en)
|
2017-06-22 |
2023-12-21 |
Amgen Inc. |
Device activation impact/shock reduction
|
MX2019015479A
(en)
|
2017-06-23 |
2020-02-20 |
Amgen Inc |
Electronic drug delivery device comprising a cap activated by a switch assembly.
|
WO2019014014A1
(en)
|
2017-07-14 |
2019-01-17 |
Amgen Inc. |
Needle insertion-retraction system having dual torsion spring system
|
JP2020527376A
(en)
|
2017-07-21 |
2020-09-10 |
アムジエン・インコーポレーテツド |
Gas permeable sealing material and assembly method for drug containers
|
JP7242562B2
(en)
|
2017-07-25 |
2023-03-20 |
アムジエン・インコーポレーテツド |
Drug delivery device with container access system and associated method of assembly
|
EP3658203B1
(en)
|
2017-07-25 |
2022-08-31 |
Amgen Inc. |
Drug delivery device with gear module and related method of assembly
|
MA49838A
(en)
|
2017-08-09 |
2020-06-17 |
Amgen Inc |
DRUG DELIVERY SYSTEM WITH CHAMBER HYDRAULIC-PNEUMATIC PRESSURE
|
US11077246B2
(en)
|
2017-08-18 |
2021-08-03 |
Amgen Inc. |
Wearable injector with sterile adhesive patch
|
US11103636B2
(en)
|
2017-08-22 |
2021-08-31 |
Amgen Inc. |
Needle insertion mechanism for drug delivery device
|
US11759565B2
(en)
|
2017-10-04 |
2023-09-19 |
Amgen Inc. |
Flow adapter for drug delivery device
|
EP4257164A3
(en)
|
2017-10-06 |
2024-01-17 |
Amgen Inc. |
Drug delivery device with interlock assembly and related method of assembly
|
US11464903B2
(en)
|
2017-10-09 |
2022-10-11 |
Amgen Inc. |
Drug delivery device with drive assembly and related method of assembly
|
WO2019090086A1
(en)
|
2017-11-03 |
2019-05-09 |
Amgen Inc. |
Systems and approaches for sterilizing a drug delivery device
|
MA50569A
(en)
|
2017-11-06 |
2020-09-16 |
Amgen Inc |
FILLING-FINISHING UNITS AND ASSOCIATED PROCESSES
|
MA50553A
(en)
|
2017-11-06 |
2020-09-16 |
Amgen Inc |
DRUG ADMINISTRATION DEVICE WITH POSITIONING AND FLOW DETECTION
|
JP7247174B2
(en)
|
2017-11-10 |
2023-03-28 |
アムジエン・インコーポレーテツド |
plunger for drug delivery device
|
MA50903A
(en)
|
2017-11-16 |
2021-05-12 |
Amgen Inc |
SELF-INJECTOR WITH STALL AND END POINT DETECTION
|
AU2018368340B2
(en)
|
2017-11-16 |
2024-03-07 |
Amgen Inc. |
Door latch mechanism for drug delivery device
|
US10835685B2
(en)
|
2018-05-30 |
2020-11-17 |
Amgen Inc. |
Thermal spring release mechanism for a drug delivery device
|
US11083840B2
(en)
|
2018-06-01 |
2021-08-10 |
Amgen Inc. |
Modular fluid path assemblies for drug delivery devices
|
CA3103681A1
(en)
|
2018-07-24 |
2020-01-30 |
Amgen Inc. |
Delivery devices for administering drugs
|
WO2020023220A1
(en)
|
2018-07-24 |
2020-01-30 |
Amgen Inc. |
Hybrid drug delivery devices with tacky skin attachment portion and related method of preparation
|
MA53375A
(en)
|
2018-07-24 |
2021-06-02 |
Amgen Inc |
ADMINISTRATION DEVICES FOR THE ADMINISTRATION OF MEDICINES
|
US20210228815A1
(en)
|
2018-07-24 |
2021-07-29 |
Amgen Inc. |
Hybrid drug delivery devices with grip portion
|
MA53320A
(en)
|
2018-07-31 |
2021-11-03 |
Amgen Inc |
FLUID PATH ASSEMBLY FOR DRUG DELIVERY DEVICE
|
US20210346601A1
(en)
|
2018-09-24 |
2021-11-11 |
Amgen Inc. |
Interventional dosing systems and methods
|
WO2020068476A1
(en)
|
2018-09-28 |
2020-04-02 |
Amgen Inc. |
Muscle wire escapement activation assembly for a drug delivery device
|
AR116679A1
(en)
|
2018-10-02 |
2021-06-02 |
Amgen Inc |
INJECTION SYSTEMS FOR THE ADMINISTRATION OF DRUGS WITH INTERNAL FORCE TRANSMISSION
|
US20210338936A1
(en)
|
2018-10-05 |
2021-11-04 |
Amgen Inc. |
Drug delivery device having dose indicator
|
EP3866890A1
(en)
|
2018-10-15 |
2021-08-25 |
Amgen Inc. |
Drug delivery device having damping mechanism
|
CA3109988A1
(en)
|
2018-10-15 |
2020-04-23 |
Amgen Inc. |
Platform assembly process for drug delivery device
|
WO2020091981A1
(en)
|
2018-11-01 |
2020-05-07 |
Amgen Inc. |
Drug delivery devices with partial drug delivery member retraction
|
EP3873567A1
(en)
|
2018-11-01 |
2021-09-08 |
Amgen Inc. |
Drug delivery devices with partial needle retraction
|
WO2020091956A1
(en)
|
2018-11-01 |
2020-05-07 |
Amgen Inc. |
Drug delivery devices with partial drug delivery member retraction
|
MX2021012557A
(en)
|
2019-04-24 |
2021-11-12 |
Amgen Inc |
Syringe sterilization verification assemblies and methods.
|
US20220273887A1
(en)
|
2019-08-23 |
2022-09-01 |
Amgen Inc. |
Drug delivery device with configurable needle shield engagement components and related methods
|
CA3217207A1
(en)
|
2021-05-21 |
2022-11-24 |
Amgen Inc. |
Method of optimizing a filling recipe for a drug container
|