AU7494100A - Charge-modified nucleic acid terminators - Google Patents

Charge-modified nucleic acid terminators

Info

Publication number
AU7494100A
AU7494100A AU74941/00A AU7494100A AU7494100A AU 7494100 A AU7494100 A AU 7494100A AU 74941/00 A AU74941/00 A AU 74941/00A AU 7494100 A AU7494100 A AU 7494100A AU 7494100 A AU7494100 A AU 7494100A
Authority
AU
Australia
Prior art keywords
charge
nucleic acid
modified nucleic
terminators
acid terminators
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU74941/00A
Inventor
Matthew Bull
Patrick Finn
Parke Flick
Shiv Kumar
Satayam Nampalli
John Nelson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Global Life Sciences Solutions USA LLC
Original Assignee
Amersham Pharmacia Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham Pharmacia Biotech Inc filed Critical Amersham Pharmacia Biotech Inc
Publication of AU7494100A publication Critical patent/AU7494100A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU74941/00A 1999-09-17 2000-09-16 Charge-modified nucleic acid terminators Abandoned AU7494100A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15473999P 1999-09-17 1999-09-17
US60154739 1999-09-17
PCT/US2000/025433 WO2001019841A1 (en) 1999-09-17 2000-09-16 Charge-modified nucleic acid terminators

Publications (1)

Publication Number Publication Date
AU7494100A true AU7494100A (en) 2001-04-17

Family

ID=22552575

Family Applications (1)

Application Number Title Priority Date Filing Date
AU74941/00A Abandoned AU7494100A (en) 1999-09-17 2000-09-16 Charge-modified nucleic acid terminators

Country Status (4)

Country Link
EP (1) EP1214332A1 (en)
AU (1) AU7494100A (en)
CA (1) CA2382063A1 (en)
WO (1) WO2001019841A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002030944A2 (en) * 2000-10-11 2002-04-18 Applera Corporation Fluorescent nucleobase conjugates having anionic linkers
US7256019B2 (en) 2001-08-29 2007-08-14 Ge Healthcare Bio-Sciences Corp. Terminal phosphate blocked nucleoside polyphosphates
DE60316103T2 (en) 2002-07-18 2008-05-29 Protein Express Co., Ltd., Choshi aminoacyl-tRNA linked to labeled p-aminophenylalanine or tyrosine
CN101258220A (en) 2004-09-16 2008-09-03 阿普里拉股份有限公司 Fluorescent dye compounds, conjugates and uses thereof
EP1886145A2 (en) 2005-05-03 2008-02-13 Applera Corporation Fluorescent detection system and dye set for use therewith
US20090246762A1 (en) * 2008-03-31 2009-10-01 Applera Corporation, Applied Biosystems Group Nucleic acid terminators incorporating a cationic moiety and methods for their use
JP4621926B2 (en) 2008-07-24 2011-02-02 国立大学法人九州大学 Enzyme substrate-modified nucleoside triphosphate, nucleic acid probe, multilabeled nucleic acid probe, method for producing multilabeled nucleic acid probe, and method for detecting target nucleic acid
WO2013056841A1 (en) 2011-10-19 2013-04-25 Inra (Institut National De La Recherche Agronomique) A method for diagnosing tse
JP5509440B2 (en) * 2012-06-22 2014-06-04 国立大学法人九州大学 Method for producing protein-nucleic acid complex and method for detecting target
TW202245800A (en) 2020-02-18 2022-12-01 美商基利科學股份有限公司 Antiviral compounds
TWI794742B (en) 2020-02-18 2023-03-01 美商基利科學股份有限公司 Antiviral compounds
JP7429799B2 (en) 2020-02-18 2024-02-08 ギリアード サイエンシーズ， インコーポレイテッド antiviral compounds
AU2022256476A1 (en) 2021-04-16 2023-10-12 Gilead Sciences, Inc. Methods of preparing carbanucleosides using amides
US12116380B2 (en) 2021-08-18 2024-10-15 Gilead Sciences, Inc. Phospholipid compounds and methods of making and using the same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340806C (en) * 1986-07-02 1999-11-02 James Merrill Prober Method, system and reagents for dna sequencing
US5187085A (en) * 1990-09-28 1993-02-16 Applied Biosystems, Inc. Nucleic acid sequence analysis with nucleoside-5'-o-(1-thiotriphosphates)
WO1996011937A1 (en) * 1994-10-14 1996-04-25 Stratagene Porphyrin labeling of polynucleotides
US5843658A (en) * 1995-03-10 1998-12-01 Hamamatsu Photonics K.K. Method of measuring oligonucleotide decomposing activity
US5986086A (en) * 1997-06-20 1999-11-16 Amersham Pharmacia Biotech Inc. Non-sulfonated cyanine dyes for labeling nucleosides and nucleotides
JP2002510466A (en) * 1998-01-23 2002-04-09 アマーシャム・ファルマシア・バイオテック・インコーポレーテッド Methods, reagent solutions and kits for DNA sequencing
JP4306960B2 (en) * 1998-02-04 2009-08-05 ジーイー・ヘルスケア・バイオサイエンス・コーポレイション Dideoxy dye terminator
GB2341189B (en) * 1998-08-31 2001-06-13 Amersham Pharm Biotech Inc Energy transfer dyes

Also Published As

Publication number Publication date
EP1214332A1 (en) 2002-06-19
CA2382063A1 (en) 2001-03-22
WO2001019841A1 (en) 2001-03-22

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase