AU2001268513A1 - Nucleic acid accessible hybridization sites - Google Patents
Nucleic acid accessible hybridization sitesInfo
- Publication number
- AU2001268513A1 AU2001268513A1 AU2001268513A AU6851301A AU2001268513A1 AU 2001268513 A1 AU2001268513 A1 AU 2001268513A1 AU 2001268513 A AU2001268513 A AU 2001268513A AU 6851301 A AU6851301 A AU 6851301A AU 2001268513 A1 AU2001268513 A1 AU 2001268513A1
- Authority
- AU
- Australia
- Prior art keywords
- nucleic acid
- hybridization sites
- acid accessible
- accessible
- hybridization
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- AIDS & HIV (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21230800P | 2000-06-17 | 2000-06-17 | |
US60/212,308 | 2000-06-17 | ||
PCT/US2001/019401 WO2001098537A2 (en) | 2000-06-17 | 2001-06-15 | Nucleic acid accessible hybridization sites |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001268513A1 true AU2001268513A1 (en) | 2002-01-02 |
Family
ID=22790472
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001268513A Abandoned AU2001268513A1 (en) | 2000-06-17 | 2001-06-15 | Nucleic acid accessible hybridization sites |
Country Status (3)
Country | Link |
---|---|
US (2) | US7060436B2 (en) |
AU (1) | AU2001268513A1 (en) |
WO (1) | WO2001098537A2 (en) |
Families Citing this family (59)
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US7101672B2 (en) * | 1998-05-05 | 2006-09-05 | Third Wave Technologies, Inc. | Target-dependent reactions using structure-bridging oligonucleotides |
ATE421999T1 (en) * | 1999-07-09 | 2009-02-15 | Gen Probe Inc | DETECTION OF HIV-1 BY AMPLIFICATION OF NUCLEIC ACIDS |
US7118860B2 (en) * | 1999-10-29 | 2006-10-10 | Stratagene California | Methods for detection of a target nucleic acid by capture |
US6984522B2 (en) | 2000-08-03 | 2006-01-10 | Regents Of The University Of Michigan | Isolation and use of solid tumor stem cells |
US7229774B2 (en) | 2001-08-02 | 2007-06-12 | Regents Of The University Of Michigan | Expression profile of prostate cancer |
US7094542B2 (en) | 2001-09-18 | 2006-08-22 | Gen-Probe Incorporated | Detection of rpoB sequences of Mycobacterium tuberculosis |
EP1953244A1 (en) | 2002-01-09 | 2008-08-06 | Nakamura, Yusuke | Cancer profiles |
WO2003067399A2 (en) * | 2002-02-07 | 2003-08-14 | Byington Carrie L | Method for creating and using a treatment protocol |
US20040024193A1 (en) * | 2002-07-26 | 2004-02-05 | Williams Gregg T. | Method of detecting and quantifying hepatitis C virus |
US20040077567A1 (en) * | 2002-10-16 | 2004-04-22 | Isis Pharmaceuticals Inc. | Antisense modulation of CD36 expression |
US20040076621A1 (en) * | 2002-10-16 | 2004-04-22 | Isis Pharmaceuticals Inc. | Antisense modulation of CD36 expression |
US7312033B2 (en) | 2002-11-14 | 2007-12-25 | Third Wave Technologies, Inc. | CFTR allele detection assays |
US8206904B2 (en) | 2002-12-18 | 2012-06-26 | Third Wave Technologies, Inc. | Detection of nucleic acids |
MXPA05006633A (en) | 2002-12-18 | 2006-05-25 | Third Wave Tech Inc | Detection of small nucleic acids. |
US7700750B2 (en) | 2003-01-09 | 2010-04-20 | Third Wave Technologies, Inc. | Connexin allele detection assays |
US20040161749A1 (en) | 2003-01-24 | 2004-08-19 | Hall Jeff G. | 3' end tagged oligonucleotides |
GB0310270D0 (en) * | 2003-05-03 | 2003-06-11 | Univ Edinburgh | Biomolecular devices |
US20060019256A1 (en) | 2003-06-09 | 2006-01-26 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
AU2005237396B2 (en) * | 2004-01-02 | 2010-02-25 | University Of Rochester | Method of identifying hairpin DNA probes by partial fold analysis |
CA2552949C (en) | 2004-01-07 | 2012-10-02 | Third Wave Technologies, Inc. | Determination of hepatitis c virus genotype |
US8076304B2 (en) | 2004-04-26 | 2011-12-13 | The Regents Of The University Of Colorado | Methods and compositions for the diagnosis and treatment of cyclin A-1 associated conditions |
US20100152280A1 (en) * | 2004-05-24 | 2010-06-17 | Isis Pharmaceuticals, Inc. | Modulation of sid-1 expression |
US7858323B2 (en) | 2004-06-09 | 2010-12-28 | The Regents Of The University Of Michigan | Phage microarray profiling of the humoral response to disease |
US20070015176A1 (en) * | 2005-02-18 | 2007-01-18 | Applera Corporation | Small nucleic acid detection probes and uses thereof |
US20070020671A1 (en) * | 2005-07-12 | 2007-01-25 | Radtkey Ray R | Method for detecting large mutations and duplications using control amplification comparisons to paralogous genes |
DE06814528T1 (en) | 2005-09-12 | 2012-01-05 | The Regent Of The University Of Michigan | RECURRING GENUS FOR PROSTATE CANCER |
WO2007035527A2 (en) * | 2005-09-15 | 2007-03-29 | Duke University | Non-fouling polymeric surface modification and signal amplification method for biomolecular detection |
WO2007047907A2 (en) | 2005-10-14 | 2007-04-26 | The Regents Of The University Of Michigan | Dek protein compositions and methods of using the same |
US7794951B2 (en) | 2005-10-18 | 2010-09-14 | University Of Massachusetts Medical School | SREBP2gc transcription factors and uses thereof |
WO2007053577A2 (en) | 2005-10-31 | 2007-05-10 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for diagnosing and treating cancer |
US7723477B2 (en) | 2005-10-31 | 2010-05-25 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth |
US7482127B2 (en) * | 2005-11-03 | 2009-01-27 | Third Wave Technologies, Inc. | Nucleic acid detection assays employing blocker oligonucleotides |
WO2007143097A1 (en) | 2006-06-01 | 2007-12-13 | Third Wave Technologies, Inc. | Detection of nucleic acids |
US7759062B2 (en) | 2006-06-09 | 2010-07-20 | Third Wave Technologies, Inc. | T-structure invasive cleavage assays, consistent nucleic acid dispensing, and low level target nucleic acid detection |
US7772390B1 (en) | 2006-07-18 | 2010-08-10 | The Regents Of The University Of California | Lipid mediated nucleic acid synthesis |
EP2079754B1 (en) | 2006-10-04 | 2017-03-15 | Third Wave Technologies, Inc. | Snap-back primers and detectable hairpin structures |
US20090324596A1 (en) | 2008-06-30 | 2009-12-31 | The Trustees Of Princeton University | Methods of identifying and treating poor-prognosis cancers |
US10745701B2 (en) | 2007-06-28 | 2020-08-18 | The Trustees Of Princeton University | Methods of identifying and treating poor-prognosis cancers |
CA2692441C (en) | 2007-07-06 | 2020-01-21 | The Regents Of The University Of Michigan | Solute carrier family 45 member 3 (slc45a3) and ets family gene fusions in prostate cancer |
US8957002B2 (en) | 2007-11-05 | 2015-02-17 | University Of Rochester | DNA microarray having hairpin probes tethered to nanostructured metal surface |
EP2247741A4 (en) * | 2008-02-03 | 2011-02-23 | Helicos Biosciences Corp | Paired-end reads in sequencing by synthesis |
BRPI0908748A2 (en) | 2008-03-15 | 2015-07-28 | Hologic Inc | Compositions and methods for analysis of nucleic acid molecules during amplification reactions |
US8796184B2 (en) | 2008-03-28 | 2014-08-05 | Sentilus, Inc. | Detection assay devices and methods of making and using the same |
JP5792621B2 (en) | 2008-09-26 | 2015-10-14 | オンコメッド ファーマシューティカルズ インコーポレイテッド | Frizzled binders and uses thereof |
TWI535445B (en) | 2010-01-12 | 2016-06-01 | 安可美德藥物股份有限公司 | Wnt antagonists and methods of treatment and screening |
EP3450979A3 (en) | 2010-03-17 | 2019-04-24 | The Regents of The University of Michigan | Using phage epitopes to profile the immune response |
MX347515B (en) | 2010-04-01 | 2017-04-28 | Oncomed Pharmaceuticals Inc * | Frizzled-binding agents and uses thereof. |
US8715937B2 (en) | 2010-11-15 | 2014-05-06 | Exact Sciences Corporation | Mutation detection assay |
US8916344B2 (en) | 2010-11-15 | 2014-12-23 | Exact Sciences Corporation | Methylation assay |
US8361720B2 (en) | 2010-11-15 | 2013-01-29 | Exact Sciences Corporation | Real time cleavage assay |
WO2013001372A2 (en) | 2011-06-30 | 2013-01-03 | University Of Oslo | Methods and compositions for inhibition of activation of regulatory t cells |
CA2840856C (en) | 2011-07-06 | 2017-09-19 | Sykehuset Sorlandet Hf | Egfr targeted therapy |
US9127318B2 (en) | 2011-10-18 | 2015-09-08 | Exact Sciences Corporation | Multiplexed KRAS mutation detection assay |
EP2911691B1 (en) | 2012-10-23 | 2018-10-10 | OncoMed Pharmaceuticals, Inc. | Methods of treating neuroendocrine tumors using wnt pathway-binding agents |
EA037709B1 (en) | 2012-12-21 | 2021-05-13 | Сюкехюсе Сёрланне Хф | Method for treatment of neurological pain |
WO2014121196A1 (en) | 2013-02-04 | 2014-08-07 | Oncomed Pharmaceuticals, Inc. | Methods and monitoring of treatment with a wnt pathway inhibitor |
WO2014158628A1 (en) | 2013-03-14 | 2014-10-02 | Hologic, Inc. | Compositions and methods for analysis of nucleic acid molecules |
US9168300B2 (en) | 2013-03-14 | 2015-10-27 | Oncomed Pharmaceuticals, Inc. | MET-binding agents and uses thereof |
CN111118119B (en) * | 2019-12-18 | 2023-09-26 | 杭州瑞普基因科技有限公司 | Method for enriching and detecting target mutation by using blocker of base mismatch |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5541308A (en) * | 1986-11-24 | 1996-07-30 | Gen-Probe Incorporated | Nucleic acid probes for detection and/or quantitation of non-viral organisms |
US5712088A (en) * | 1987-11-18 | 1998-01-27 | Chiron Corporation | Methods for detecting Hepatitis C virus using polynucleotides specific for same |
GB8822228D0 (en) | 1988-09-21 | 1988-10-26 | Southern E M | Support-bound oligonucleotides |
US5427930A (en) | 1990-01-26 | 1995-06-27 | Abbott Laboratories | Amplification of target nucleic acids using gap filling ligase chain reaction |
US5494810A (en) | 1990-05-03 | 1996-02-27 | Cornell Research Foundation, Inc. | Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease |
US5994069A (en) | 1996-01-24 | 1999-11-30 | Third Wave Technologies, Inc. | Detection of nucleic acids by multiple sequential invasive cleavages |
US5846717A (en) | 1996-01-24 | 1998-12-08 | Third Wave Technologies, Inc. | Detection of nucleic acid sequences by invader-directed cleavage |
EP1752545A3 (en) * | 1991-12-23 | 2007-12-26 | Novartis Vaccines and Diagnostics, Inc. | HIV probes for use in solution phase sandwich hybridization assays |
US5843654A (en) | 1992-12-07 | 1998-12-01 | Third Wave Technologies, Inc. | Rapid detection of mutations in the p53 gene |
US6372424B1 (en) | 1995-08-30 | 2002-04-16 | Third Wave Technologies, Inc | Rapid detection and identification of pathogens |
US5422253A (en) | 1992-12-07 | 1995-06-06 | Wisconsin Alumni Research Foundation | Method of site specific nucleic acid cleavage |
US5429807A (en) | 1993-10-28 | 1995-07-04 | Beckman Instruments, Inc. | Method and apparatus for creating biopolymer arrays on a solid support surface |
US5712095A (en) * | 1994-06-16 | 1998-01-27 | Becton Dickinson And Company | Rapid and sensitive detection of antibiotic-resistant mycobacteria using oligonucleotide probes specific for ribosomal RNA precursors |
JPH10509322A (en) | 1994-11-09 | 1998-09-14 | サード ウェーヴ テクノロジーズ,インコーポレーテッド | Rapid detection and identification of nucleic acid variants and pathogens |
US5599695A (en) | 1995-02-27 | 1997-02-04 | Affymetrix, Inc. | Printing molecular library arrays using deprotection agents solely in the vapor phase |
CA2243353C (en) | 1996-01-24 | 2010-03-30 | Third Wave Technologies, Inc. | Invasive cleavage of nucleic acids |
US5985557A (en) | 1996-01-24 | 1999-11-16 | Third Wave Technologies, Inc. | Invasive cleavage of nucleic acids |
US5962226A (en) | 1996-11-26 | 1999-10-05 | Incyte Pharmaceuticals, Inc. | Human RNA-binding protein |
US5846723A (en) * | 1996-12-20 | 1998-12-08 | Geron Corporation | Methods for detecting the RNA component of telomerase |
US6046004A (en) * | 1997-02-27 | 2000-04-04 | Lorne Park Research, Inc. | Solution hybridization of nucleic acids with antisense probes having modified backbones |
WO1999007890A1 (en) * | 1997-08-05 | 1999-02-18 | University Of Massachusetts | Nucleic acid isolation, quantitation, and structure probing |
JP2001514884A (en) * | 1997-08-19 | 2001-09-18 | ハイブリドン・インク | Novel HIV-specific synthetic oligonucleotides and methods of using the same |
US6511803B1 (en) * | 1997-10-10 | 2003-01-28 | President And Fellows Of Harvard College | Replica amplification of nucleic acid arrays |
US6204026B1 (en) * | 1997-11-05 | 2001-03-20 | The Board Of Trustees Of The University Of Arkansas | Detection of M. tuberculosis complex via reverse transcriptase SDA |
US6060310A (en) | 1997-11-24 | 2000-05-09 | The United States Of America As Represented By The Department Of Health And Human Services | Transcription factor decoy and tumor growth inhibitor |
-
2001
- 2001-06-15 WO PCT/US2001/019401 patent/WO2001098537A2/en active Application Filing
- 2001-06-15 AU AU2001268513A patent/AU2001268513A1/en not_active Abandoned
- 2001-06-15 US US09/882,945 patent/US7060436B2/en not_active Expired - Lifetime
-
2004
- 2004-03-23 US US10/807,114 patent/US20040235024A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20030143535A1 (en) | 2003-07-31 |
US7060436B2 (en) | 2006-06-13 |
US20040235024A1 (en) | 2004-11-25 |
WO2001098537A3 (en) | 2003-10-16 |
WO2001098537A2 (en) | 2001-12-27 |
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