AU2001272482A1 - Osteolevin gene polymorphisms - Google Patents

Osteolevin gene polymorphisms

Info

Publication number
AU2001272482A1
AU2001272482A1 AU2001272482A AU7248201A AU2001272482A1 AU 2001272482 A1 AU2001272482 A1 AU 2001272482A1 AU 2001272482 A AU2001272482 A AU 2001272482A AU 7248201 A AU7248201 A AU 7248201A AU 2001272482 A1 AU2001272482 A1 AU 2001272482A1
Authority
AU
Australia
Prior art keywords
osteolevin
gene polymorphisms
polymorphisms
gene
osteolevin gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001272482A
Inventor
Wendy Balemans
Martin Ebeling
Dorothee Foernzler
Neela Patel
Wim Van Hul
Brian Henry Vickery
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitaire Instelling Antwerpen (uia)
F Hoffmann La Roche AG
Original Assignee
UNIVERSITAIRE INSTELLING ANTWE
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UNIVERSITAIRE INSTELLING ANTWE, F Hoffmann La Roche AG filed Critical UNIVERSITAIRE INSTELLING ANTWE
Publication of AU2001272482A1 publication Critical patent/AU2001272482A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2001272482A 2000-06-19 2001-06-15 Osteolevin gene polymorphisms Abandoned AU2001272482A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00112867 2000-06-19
EP00112867.7 2000-06-19
PCT/EP2001/006795 WO2001098491A2 (en) 2000-06-19 2001-06-15 Osteolevin gene polymorphisms

Publications (1)

Publication Number Publication Date
AU2001272482A1 true AU2001272482A1 (en) 2002-01-02

Family

ID=8169000

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001272482A Abandoned AU2001272482A1 (en) 2000-06-19 2001-06-15 Osteolevin gene polymorphisms

Country Status (6)

Country Link
US (1) US20040132021A1 (en)
EP (1) EP1366156A2 (en)
JP (1) JP2004520005A (en)
AU (1) AU2001272482A1 (en)
CA (1) CA2412110A1 (en)
WO (1) WO2001098491A2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI9915679B8 (en) 1998-11-27 2021-05-25 Darwin Discovery Ltd compositions and methods to increase bone mineralization
US20040009535A1 (en) 1998-11-27 2004-01-15 Celltech R&D, Inc. Compositions and methods for increasing bone mineralization
EP2277522B1 (en) * 2002-03-01 2012-11-21 UCB Manufacturing, Inc. Methods for increasing or decreasing bone density and identifying molecules
AU2003221841A1 (en) * 2002-04-03 2003-10-27 Celltech R And D, Inc. Association of polymorphisms in the sost gene region with bone mineral density
RS20050934A (en) 2003-06-16 2008-04-04 Celltech R. & D. Inc., Antibodies specific for sclerostin and methods fo r increasing bone mineralization
WO2006010376A1 (en) * 2004-07-28 2006-02-02 Aic Method for diagnosing and treating bone-related diseases
US7592429B2 (en) 2005-05-03 2009-09-22 Ucb Sa Sclerostin-binding antibody
US8003108B2 (en) 2005-05-03 2011-08-23 Amgen Inc. Sclerostin epitopes
EP2131860B1 (en) 2007-03-20 2013-12-18 Eli Lilly & Company Anti-sclerostin antibodies
CL2008002775A1 (en) 2007-09-17 2008-11-07 Amgen Inc Use of a sclerostin binding agent to inhibit bone resorption.
DK3195880T3 (en) 2010-05-14 2020-03-02 Amgen Inc Highly Concentrated Anti-Sclerostin Antibody Formulations
MX2013010011A (en) 2011-03-01 2014-10-24 Amgen Inc Sclerostin and dkk-1 bispecific binding agents.
MA35009B1 (en) 2011-03-25 2014-04-03 Amgen Inc ANTI-SCLERROTIN ANTIBODY CRYSTALS AND FORMULATIONS THEREOF
SI2739311T1 (en) 2011-08-04 2018-07-31 Amgen Inc. Method for treating bone gap defects
JP6363954B2 (en) 2011-12-28 2018-07-25 アムジエン・インコーポレーテツド Treatment of alveolar bone loss by using anti-sclerostin antibody
EP3626267A1 (en) 2012-07-05 2020-03-25 UCB Pharma, S.A. Treatment for bone diseases
UY35148A (en) 2012-11-21 2014-05-30 Amgen Inc HETERODIMERIC IMMUNOGLOBULINS
MA41142A (en) 2014-12-12 2017-10-17 Amgen Inc ANTI-SCLEROSTINE ANTIBODIES AND THE USE OF THEM TO TREAT BONE CONDITIONS AS PART OF THE TREATMENT PROTOCOL
GB201604124D0 (en) 2016-03-10 2016-04-27 Ucb Biopharma Sprl Pharmaceutical formulation
WO2018115879A1 (en) 2016-12-21 2018-06-28 Mereo Biopharma 3 Limited Use of anti-sclerostin antibodies in the treatment of osteogenesis imperfecta
SG11202008206TA (en) 2018-03-30 2020-09-29 Amgen Inc C-terminal antibody variants

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI9915679B8 (en) * 1998-11-27 2021-05-25 Darwin Discovery Ltd compositions and methods to increase bone mineralization
AU3511100A (en) * 1999-03-12 2000-10-04 Regeneron Pharmaceuticals, Inc. Novel nucleic acids and polypeptides
ES2332916T3 (en) * 1999-06-09 2010-02-15 Genentech Inc COMPOSITIONS AND METHOD FOR TUMOR TREATMENT.
CA2410912A1 (en) * 2000-06-01 2001-12-06 Amgen, Inc. Cystine-knot polypeptides: cloaked-2 molecules and uses thereof
JP4451059B2 (en) * 2000-09-01 2010-04-14 ジェネンテック インコーポレイテッド Secreted and transmembrane polypeptides and nucleic acids encoding them

Also Published As

Publication number Publication date
CA2412110A1 (en) 2001-12-27
JP2004520005A (en) 2004-07-08
US20040132021A1 (en) 2004-07-08
WO2001098491A3 (en) 2003-10-02
WO2001098491A2 (en) 2001-12-27
EP1366156A2 (en) 2003-12-03

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