JP6716566B2 - 近接センサ付き薬物送達装置 - Google Patents

近接センサ付き薬物送達装置 Download PDF

Info

Publication number
JP6716566B2
JP6716566B2 JP2017532778A JP2017532778A JP6716566B2 JP 6716566 B2 JP6716566 B2 JP 6716566B2 JP 2017532778 A JP2017532778 A JP 2017532778A JP 2017532778 A JP2017532778 A JP 2017532778A JP 6716566 B2 JP6716566 B2 JP 6716566B2
Authority
JP
Japan
Prior art keywords
proximity sensor
plunger
housing
sensor
reservoir
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2017532778A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017538511A5 (OSRAM
JP2017538511A (ja
Inventor
マッカロー，アダム・ビー
Original Assignee
アムジエン・インコーポレーテツド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アムジエン・インコーポレーテツド filed Critical アムジエン・インコーポレーテツド
Publication of JP2017538511A publication Critical patent/JP2017538511A/ja
Publication of JP2017538511A5 publication Critical patent/JP2017538511A5/ja
Application granted granted Critical
Publication of JP6716566B2 publication Critical patent/JP6716566B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14526—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons the piston being actuated by fluid pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1454—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons spring-actuated, e.g. by a clockwork
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053—Media being expelled from injector by pressurised fluid or vacuum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/5086—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile for indicating if defective, used, tampered with or unsterile
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1581—Right-angle needle-type devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/13—General characteristics of the apparatus with means for the detection of operative contact with patient, e.g. lip sensor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3351—Controlling upstream pump pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8218—Gas operated
    • A61M2205/8225—Gas operated using incorporated gas cartridges for the driving gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M5/1684—Monitoring, detecting, signalling or eliminating infusion flow anomalies by detecting the amount of infusate remaining, e.g. signalling end of infusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16877—Adjusting flow; Devices for setting a flow rate
    • A61M5/16881—Regulating valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2046—Media being expelled from injector by gas generation, e.g. explosive charge

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
JP2017532778A 2014-12-19 2015-12-18 近接センサ付き薬物送達装置 Active JP6716566B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462094395P 2014-12-19 2014-12-19
US62/094,395 2014-12-19
PCT/US2015/066597 WO2016100781A1 (en) 2014-12-19 2015-12-18 Drug delivery device with proximity sensor

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2020099954A Division JP7049394B2 (ja) 2014-12-19 2020-06-09 近接センサ付き薬物送達装置
JP2020099955A Division JP7049395B2 (ja) 2014-12-19 2020-06-09 近接センサ付き薬物送達装置

Publications (3)

Publication Number Publication Date
JP2017538511A JP2017538511A (ja) 2017-12-28
JP2017538511A5 JP2017538511A5 (OSRAM) 2018-12-06
JP6716566B2 true JP6716566B2 (ja) 2020-07-01

Family

ID=55071250

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2017532778A Active JP6716566B2 (ja) 2014-12-19 2015-12-18 近接センサ付き薬物送達装置
JP2020099955A Active JP7049395B2 (ja) 2014-12-19 2020-06-09 近接センサ付き薬物送達装置
JP2020099954A Active JP7049394B2 (ja) 2014-12-19 2020-06-09 近接センサ付き薬物送達装置
JP2022047935A Active JP7371158B2 (ja) 2014-12-19 2022-03-24 近接センサ付き薬物送達装置

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2020099955A Active JP7049395B2 (ja) 2014-12-19 2020-06-09 近接センサ付き薬物送達装置
JP2020099954A Active JP7049394B2 (ja) 2014-12-19 2020-06-09 近接センサ付き薬物送達装置
JP2022047935A Active JP7371158B2 (ja) 2014-12-19 2022-03-24 近接センサ付き薬物送達装置

Country Status (5)

Country Link
US (5) US10799630B2 (OSRAM)
EP (2) EP3848072A1 (OSRAM)
JP (4) JP6716566B2 (OSRAM)
ES (1) ES2898469T3 (OSRAM)
WO (1) WO2016100781A1 (OSRAM)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1762259E (pt) 2005-09-12 2010-12-10 Unomedical As Insersor para um conjunto de infusão com uma primeira e uma segunda unidades de mola
EP2195052B1 (en) 2007-10-02 2019-09-04 Medimop Medical Projects Ltd. External drug pump
CN104474606B (zh) * 2009-10-13 2017-04-26 瓦莱里塔斯公司 流体输送装置
EP2552513B1 (en) 2010-03-30 2014-03-19 Unomedical A/S Medical device
US10194938B2 (en) 2011-03-14 2019-02-05 UnoMedical, AS Inserter system with transport protection
EP2583715A1 (en) 2011-10-19 2013-04-24 Unomedical A/S Infusion tube system and method for manufacture
JP6559072B2 (ja) 2013-02-19 2019-08-14 ノボ・ノルデイスク・エー／エス 軸方向スイッチを含む回転センサモジュール
WO2014128157A1 (en) 2013-02-19 2014-08-28 Novo Nordisk A/S Drug delivery device with dose capturing module
EP2958610B1 (en) 2013-02-19 2016-11-30 Novo Nordisk A/S Dose capturing cartridge module for drug delivery device
US10912888B2 (en) * 2013-07-17 2021-02-09 Sanofi Driving configuration for a drug delivery device
EP3071262B1 (en) 2013-11-21 2020-04-08 Novo Nordisk A/S Rotary sensor assembly with space efficient design
US11052198B2 (en) 2013-11-21 2021-07-06 Novo Nordisk A/S Rotary sensor assembly with axial switch and redundancy feature
WO2015075135A1 (en) * 2013-11-21 2015-05-28 Novo Nordisk A/S Rotary sensor module with resynchronization feature
EP3848072A1 (en) 2014-12-19 2021-07-14 Amgen Inc. Drug delivery device with proximity sensor
CN112545886A (zh) 2015-03-10 2021-03-26 里珍纳龙药品有限公司 无菌刺穿系统和方法
US10576207B2 (en) 2015-10-09 2020-03-03 West Pharma. Services IL, Ltd. Angled syringe patch injector
CN108430536B (zh) 2015-10-09 2022-04-08 西医药服务以色列分公司 填充定制注射筒的方法
CN108778370B (zh) 2016-01-19 2021-10-08 优诺医疗有限公司 套管和输液装置
EP3405227B1 (en) 2016-01-21 2020-06-17 West Pharma. Services Il, Ltd. Force containment in an automatic injector
JP6542481B2 (ja) 2016-01-21 2019-07-10 ウェスト ファーマ サービシーズ イスラエル リミテッド システム
US11311674B2 (en) 2016-01-21 2022-04-26 West Pharma. Services IL, Ltd. Medicament delivery device comprising a visual indicator
JOP20170042B1 (ar) 2016-02-12 2022-09-15 Amgen Inc وسيلة توصيل عقار، طريقة تصنيعه وطريقة استخدامه
US11389597B2 (en) 2016-03-16 2022-07-19 West Pharma. Services IL, Ltd. Staged telescopic screw assembly having different visual indicators
MX2018012290A (es) 2016-04-08 2019-02-07 Amgen Inc Dispositivo de administracion de farmaco, metodo de fabricacion y metodo de uso.
GB2606087B (en) 2016-06-06 2023-03-08 E3D Agricultural Cooporative Association Ltd Multiple use computerized injector
GB2552340A (en) 2016-07-19 2018-01-24 Owen Mumford Ltd Medicament delivery device
US11730892B2 (en) 2016-08-01 2023-08-22 West Pharma. Services IL, Ltd. Partial door closure prevention spring
CN109562229B (zh) 2016-08-01 2021-07-13 西医药服务以色列有限公司 抗旋转药筒销
EP3519015A1 (en) * 2016-09-27 2019-08-07 Sanofi-Aventis Deutschland GmbH A medicament delivery device
JP6646183B2 (ja) * 2016-10-10 2020-02-14 ウェスト ファーマ サービシーズ イスラエル リミテッド 針挿入および退避機構
US11278665B2 (en) 2016-11-22 2022-03-22 Eitan Medical Ltd. Method for delivering a therapeutic substance
JP7203750B2 (ja) 2017-03-15 2023-01-13 ノバルティス アーゲー 医薬品を使用するためのシステム
JP7155141B2 (ja) 2017-03-15 2022-10-18 ノバルティス アーゲー 医療装置、プログラミング装置、無線端末、および医療システム
CA3053705A1 (en) 2017-03-15 2018-09-20 Novartis Ag System for administering a pharmaceutical product
EP3595739B1 (en) 2017-03-16 2021-04-07 Novartis AG Injector device
US20200114068A1 (en) * 2017-03-16 2020-04-16 Novartis Ag Injector device
WO2018166701A1 (en) * 2017-03-16 2018-09-20 Novartis Ag Injector device
CN115025327B (zh) 2017-05-05 2024-06-28 里珍纳龙药品有限公司 自动注射器和相关使用方法
JP6921997B2 (ja) 2017-05-30 2021-08-18 ウェスト ファーマ サービシーズ イスラエル リミテッド ウェアラブル注射器のモジュラ駆動トレイン
US20190054246A1 (en) * 2017-08-17 2019-02-21 Qualcomm Incorporated Medicine delivery device
CA3073605C (en) * 2017-08-21 2023-03-21 Eli Lilly And Company Medication delivery device with sensing system
US11383038B2 (en) * 2017-09-25 2022-07-12 Insulet Corporation Pre-filled cartridge-based drug delivery device
IL272636B2 (en) * 2017-10-06 2024-10-01 Amgen Inc Drug delivery device with interlock assembly and related method of assembly
SG11202002966QA (en) * 2017-11-10 2020-05-28 Amgen Inc Plungers for drug delivery devices
EP3752220A1 (en) 2018-02-16 2020-12-23 Debiotech S.A. Status indicator of a drug delivery system
CN108392699B (zh) * 2018-04-04 2024-07-12 杨一博 用于注射的装置及其方法
US20190374722A1 (en) * 2018-06-08 2019-12-12 Abbvie Inc. Injection device with end of dose indicator
EP3820544A1 (en) * 2018-07-11 2021-05-19 Debiotech S.A. Drug delivery system
US11357909B2 (en) 2018-10-05 2022-06-14 Eitan Medical Ltd. Triggering sequence
JP2022519414A (ja) * 2018-11-13 2022-03-24 ウェスト ファーマ サービシーズ イスラエル リミテッド 注射器の針の深さセンサー
KR102655825B1 (ko) 2019-02-26 2024-04-08 벡톤 디킨슨 프랑스 청각적 표시기를 가진 자동-주사 장치
CN117547682A (zh) 2019-02-27 2024-02-13 伊莱利利公司 具有感测系统的药物输送装置
CN113543823B (zh) * 2019-05-17 2023-12-15 上海移宇科技有限公司 药物输注装置
SG11202111673SA (en) 2019-05-20 2021-11-29 Unomedical As Rotatable infusion device and methods thereof
EP3990061A1 (en) * 2019-06-25 2022-05-04 QuiO Technologies LLC A system with a monitoring device
EP3990059A1 (en) * 2019-06-26 2022-05-04 Sanofi Injection device with a filling level indicator
AU2020316106A1 (en) * 2019-07-24 2022-02-03 Enable Injections, Inc. Medical fluid injection and transfer devices and method
EP4028083B1 (en) * 2019-09-11 2025-04-09 Eli Lilly and Company Medication delivery device with needle carrier
CA3155912A1 (en) 2019-09-25 2021-04-01 Janssen Pharmaceuticals, Inc. Interconnection of drug administration systems
JP7579848B2 (ja) 2019-10-01 2024-11-08 ウノメディカル アクティーゼルスカブ コネクタ
US20240100247A1 (en) * 2019-10-08 2024-03-28 Amgen Inc. Needle insertion mechanism for drug delivery device
CA3182467A1 (en) * 2020-06-11 2021-12-16 Aescula Tech, Inc. Device for controlled injection across a variety of material properties
EP4171685A4 (en) * 2020-06-26 2024-07-17 AktiVax, Inc. AUTO-INJECTOR WITH UNIFORM PRESSURE FORCE OF A PRIMARY CONTAINER
CN116322585A (zh) * 2020-10-15 2023-06-23 爱尔康公司 无线注射器
US12447269B2 (en) * 2020-11-11 2025-10-21 Medtronic Minimed, Inc. Torsional insertion devices
US11951281B2 (en) 2020-11-11 2024-04-09 Medtronic Minimed, Inc. Fluid conduit insertion devices
US11872369B1 (en) 2021-02-18 2024-01-16 Fresenius Kabi Deutschland Gmbh Wearable medicament delivery device with leakage and skin contact sensing and method of use thereof
US11464902B1 (en) 2021-02-18 2022-10-11 Fresenius Kabi Deutschland Gmbh Wearable medicament delivery device with compressible reservoir and method of use thereof
US11311666B1 (en) 2021-02-18 2022-04-26 Fresenius Kabi Deutschland Gmbh Modular wearable medicament delivery device and method of use thereof
US11497847B1 (en) 2021-02-19 2022-11-15 Fresenius Kabi Deutschland Gmbh Wearable injector with adhesive substrate
US11344682B1 (en) 2021-02-19 2022-05-31 Fresenius Kabi Deutschland Gmbh Drug supply cartridge with visual use indicator and delivery devices that use the same
US11426523B1 (en) 2021-02-19 2022-08-30 Fresenius Kabi Deutschland Gmbh Drug delivery assembly including a removable cartridge
US11633537B1 (en) 2021-02-19 2023-04-25 Fresenius Kabi Deutschland Gmbh Drug delivery assembly including a pre-filled cartridge
US11406755B1 (en) 2021-02-19 2022-08-09 Fresenius Kabi Deutschland Gmbh Sensing fluid flow irregularities in an on-body injector
US11607505B1 (en) 2021-02-19 2023-03-21 Fresenius Kabi Deutschland Gmbh Wearable injector with sterility sensors
US11413394B1 (en) 2021-02-19 2022-08-16 Fresenius Kabi Deutschland Gmbh Display for wearable drug delivery device
EP4059541A1 (en) * 2021-03-15 2022-09-21 Sensile Medical AG Drug delivery device
US11529459B1 (en) 2021-04-30 2022-12-20 Fresenius Kabi Deutschland Gmbh Wearable injector with adhesive module
US11419976B1 (en) 2021-04-30 2022-08-23 Fresenius Kabi Deutschland Gmbh Wearable drug delivery device with pressurized fluid dispensing
US11351300B1 (en) 2021-04-30 2022-06-07 Fresenius Kabl Deutschland GmbH Drug dispensing system with replaceable drug supply cartridges
US11504470B1 (en) 2021-04-30 2022-11-22 Fresenius Kabi Deutschland Gmbh Deformable drug reservoir for wearable drug delivery device
US11717608B1 (en) 2021-05-03 2023-08-08 Fresenius Kabi Deutschland Gmbh Drug delivery assembly including an adhesive pad
US11484646B1 (en) 2021-05-04 2022-11-01 Fresenius Kabi Deutschland Gmbh Sealing systems for a reservoir of an on-body injector
USD1007676S1 (en) 2021-11-16 2023-12-12 Regeneron Pharmaceuticals, Inc. Wearable autoinjector
GB2621636B (en) * 2022-08-19 2024-11-27 Shaily Uk Ltd Medicament delivery device
WO2024102815A1 (en) * 2022-11-09 2024-05-16 The General Hospital Corporation Systems and methods for hair transplantation with split needle device
US20250195752A1 (en) * 2023-12-19 2025-06-19 Becton, Dickinson And Company Fillable medicament delivery device

Family Cites Families (305)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6241704B1 (en) 1901-11-22 2001-06-05 Sims Deltec, Inc. Drug pump systems and methods
US4386606A (en) 1979-12-26 1983-06-07 Waters Instruments, Inc. Syringe lock
US4417889A (en) 1980-12-31 1983-11-29 Choi Soo Bong Device for a portable automatic syringe
US4703008A (en) 1983-12-13 1987-10-27 Kiren-Amgen, Inc. DNA sequences encoding erythropoietin
NZ210501A (en) 1983-12-13 1991-08-27 Kirin Amgen Inc Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
KR850004274A (ko) 1983-12-13 1985-07-11 원본미기재 에리트로포이에틴의 제조방법
US4559038A (en) 1984-10-19 1985-12-17 Deltec Systems, Inc. Drug delivery system
US5222362A (en) 1989-01-10 1993-06-29 Maus Daryl D Heat-activated drug delivery system and thermal actuators therefor
US5856298A (en) 1989-10-13 1999-01-05 Amgen Inc. Erythropoietin isoforms
US7217689B1 (en) 1989-10-13 2007-05-15 Amgen Inc. Glycosylation analogs of erythropoietin
AU646822B2 (en) 1989-10-13 1994-03-10 Kirin-Amgen Inc. Erythropoietin isoforms
IL110669A (en) 1993-08-17 2008-11-26 Kirin Amgen Inc Erythropoietin analogs
US6562596B1 (en) 1993-10-06 2003-05-13 Amgen Inc. Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods
US5773569A (en) 1993-11-19 1998-06-30 Affymax Technologies N.V. Compounds and peptides that bind to the erythropoietin receptor
US5830851A (en) 1993-11-19 1998-11-03 Affymax Technologies N.V. Methods of administering peptides that bind to the erythropoietin receptor
US5582593A (en) 1994-07-21 1996-12-10 Hultman; Barry W. Ambulatory medication delivery system
US5885574A (en) 1994-07-26 1999-03-23 Amgen Inc. Antibodies which activate an erythropoietin receptor
IL114909A (en) 1994-08-12 1999-10-28 Immunomedics Inc Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells
US5730723A (en) 1995-10-10 1998-03-24 Visionary Medical Products Corporation, Inc. Gas pressured needle-less injection device and method
US5686292A (en) 1995-06-02 1997-11-11 Genentech, Inc. Hepatocyte growth factor receptor antagonist antibodies and uses thereof
US5767078A (en) 1995-06-07 1998-06-16 Johnson; Dana L. Agonist peptide dimers
ZA9610374B (en) 1995-12-11 1997-06-23 Elan Med Tech Cartridge-based drug delivery device
US5830187A (en) 1995-12-22 1998-11-03 Science Incorporated Fluid delivery device with conformable ullage and fill assembly
US5879143A (en) 1996-04-26 1999-03-09 Sims Deltec, Inc. Reservoir enclosure adaptors and methods
US6176845B1 (en) 1996-12-18 2001-01-23 Science Incorporated Fluid delivery apparatus with flow indicator and vial fill
US20010039397A1 (en) 1996-12-18 2001-11-08 Kriesell Marshall S. Fluid delivery apparatus with flow indicator and vial fill
US6355019B1 (en) 1996-12-18 2002-03-12 Science Incorporated Variable rate infusion apparatus with indicator and adjustable rate control
US6183441B1 (en) 1996-12-18 2001-02-06 Science Incorporated Variable rate infusion apparatus with indicator and adjustable rate control
JPH1121116A (ja) 1997-06-30 1999-01-26 Nippon Steel Corp 窒化ホウ素で被覆された炭素質粉末および炭素質繊維
ATE375363T1 (de) 1997-07-14 2007-10-15 Bolder Biotechnology Inc Derivate des wachstumshormons und verwandte proteine
US6753165B1 (en) 1999-01-14 2004-06-22 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
PT986644E (pt) 1997-07-23 2007-01-31 Roche Diagnostics Gmbh Preparação de eritropoietina por activação genética endógena com promotores virais
US6030086A (en) 1998-03-02 2000-02-29 Becton, Dickinson And Company Flash tube reflector with arc guide
EP1064035B1 (en) 1998-03-23 2003-11-26 ELAN CORPORATION, Plc Drug delivery device
US6310078B1 (en) 1998-04-20 2001-10-30 Ortho-Mcneil Pharmaceutical, Inc. Substituted amino acids as erythropoietin mimetics
CA2330527A1 (en) 1998-06-15 1999-12-23 Genzyme Transgenics Corporation Erythropoietin analog-human serum albumin fusion
US20050181482A1 (en) 2004-02-12 2005-08-18 Meade Harry M. Method for the production of an erythropoietin analog-human IgG fusion proteins in transgenic mammal milk
HK1040944B (en) 1998-10-23 2007-09-07 Amgen Inc. Methods and compositions for the prevention and treatment of anemia
DK1783222T3 (da) 1998-10-23 2012-07-09 Kirin Amgen Inc Dimere trombopoietiske peptidomimetika, der binder til MPL-receptor og har trombopoietisk aktivitet
US7621893B2 (en) 1998-10-29 2009-11-24 Medtronic Minimed, Inc. Methods and apparatuses for detecting occlusions in an ambulatory infusion pump
US7766873B2 (en) 1998-10-29 2010-08-03 Medtronic Minimed, Inc. Method and apparatus for detecting occlusions in an ambulatory infusion pump
NZ512122A (en) 1998-11-27 2003-12-19 Darwin Discovery Ltd Compositions and methods for increasing bone mineralization
EP1006184A1 (en) 1998-12-03 2000-06-07 F. Hoffmann-La Roche Ag IGF-1 receptor interacting proteins (IIPs) genes coding therefor and uses thereof
JP2002544123A (ja) 1999-04-14 2002-12-24 スミスクライン・ビーチャム・コーポレイション エリトロポイエチン受容体抗体
US7297680B2 (en) 1999-04-15 2007-11-20 Crucell Holland B.V. Compositions of erythropoietin isoforms comprising Lewis-X structures and high sialic acid content
CZ299516B6 (cs) 1999-07-02 2008-08-20 F. Hoffmann-La Roche Ag Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem
CA2388617A1 (en) 1999-10-22 2001-05-03 Millennium Pharmaceuticals, Inc. Nucleic acid molecules derived from rat brain and programmed cell death models
US20050202538A1 (en) 1999-11-12 2005-09-15 Merck Patent Gmbh Fc-erythropoietin fusion protein with improved pharmacokinetics
AU2154401A (en) 1999-11-12 2001-05-30 Merck Patent Gmbh Erythropoietin forms with improved properties
US7223593B2 (en) 2000-01-21 2007-05-29 Biovex Limited Herpes virus strains for gene therapy
US6758810B2 (en) 2000-01-21 2004-07-06 Medtronic Minimed, Inc. Ambulatory medical apparatus and method using a robust communication protocol
AUPQ599700A0 (en) 2000-03-03 2000-03-23 Super Internet Site System Pty Ltd On-line geographical directory
US6586398B1 (en) 2000-04-07 2003-07-01 Amgen, Inc. Chemically modified novel erythropoietin stimulating protein compositions and methods
EP2292651A1 (en) 2000-04-21 2011-03-09 Amgen Inc. Methods and compositions for the prevention and treatment of anemia
US6756480B2 (en) 2000-04-27 2004-06-29 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
US7078376B1 (en) 2000-08-11 2006-07-18 Baxter Healthcare S.A. Therapeutic methods for treating subjects with a recombinant erythropoietin having high activity and reduced side effects
JP2004518621A (ja) 2000-09-08 2004-06-24 グリフォン セラピューティクス，インコーポレーテッド 「擬似」天然型化学的ライゲーション
ES2287156T3 (es) 2000-09-08 2007-12-16 Insulet Corporation Dispositivos y sistemas para la infusion de un paciente.
US7271689B1 (en) 2000-11-22 2007-09-18 Fonar Corporation Magnet structure
DE60144439D1 (de) 2000-12-20 2011-05-26 Hoffmann La Roche Konjugate von erythropoietin (epo) mit polyethylenglykol (peg)
MX337162B (es) 2001-01-05 2016-02-15 Pfizer Anticuerpos contra el receptor del factor de crecimiento similar a insulina.
AU2002319142B2 (en) 2001-04-04 2008-02-21 Genodyssee New polynucleotides and polypeptides of the erythropoietin gene
US20040035491A1 (en) 2002-08-26 2004-02-26 Penjet Corporation Method and apparatus for needle-less injection with a degassed fluid
CN100448891C (zh) 2001-05-11 2009-01-07 安姆根有限公司 与tall-1结合的肽和相关分子
US20120209197A1 (en) 2002-01-04 2012-08-16 Lanigan Richard J Infusion pump assembly
US8034026B2 (en) 2001-05-18 2011-10-11 Deka Products Limited Partnership Infusion pump assembly
NZ530765A (en) 2001-06-26 2006-11-30 Amgen Fremont Inc Antibodies that bind OPGL and compositions and methods for the treatment of bone diseases
US6900292B2 (en) 2001-08-17 2005-05-31 Lee-Hwei K. Sun Fc fusion proteins of human erythropoietin with increased biological activities
NZ531211A (en) 2001-08-23 2007-04-27 Genmad As Human antibodies specific for interleukin 15 (IL-15)
US7247304B2 (en) 2001-08-23 2007-07-24 Genmab A/S Methods of treating using anti-IL-15 antibodies
US6930086B2 (en) 2001-09-25 2005-08-16 Hoffmann-La Roche Inc. Diglycosylated erythropoietin
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7521053B2 (en) 2001-10-11 2009-04-21 Amgen Inc. Angiopoietin-2 specific binding agents
US7138370B2 (en) 2001-10-11 2006-11-21 Amgen Inc. Specific binding agents of human angiopoietin-2
US7429258B2 (en) 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US7204823B2 (en) 2001-12-19 2007-04-17 Medtronic Minimed, Inc. Medication delivery system and monitor
WO2003055526A2 (en) 2001-12-21 2003-07-10 Maxygen Aps Erythropoietin conjugates
US7241444B2 (en) 2002-01-18 2007-07-10 Pierre Fabre Medicament Anti-IGF-IR antibodies and uses thereof
EP1806364B1 (fr) 2002-01-18 2013-07-31 Pierre Fabre Medicament Nouveaux anticorps anti-igf-ir et leurs applications
EP1470232A1 (en) 2002-01-31 2004-10-27 Oxford Biomedica (UK) Limited Physiologically regulated erythropoietin-expressing vector for the treatment of anaemia
GB0202252D0 (en) 2002-01-31 2002-03-20 Oxford Biomedica Ltd Anemia
ATE402724T1 (de) 2002-02-18 2008-08-15 Danfoss As Vorrichtung zur verabreichung eines medikaments in flüssiger form
US20050027264A1 (en) 2002-02-28 2005-02-03 Fleury Michael T. Huber needle with anti-rebound safety mechanism
US6878136B2 (en) 2002-02-28 2005-04-12 Medical Product Specialists Huber needle with anti-rebound safety mechanism
US6918894B2 (en) 2002-02-28 2005-07-19 Medical Product Specialists Huber needle with anti-rebound safety mechanism
US7033338B2 (en) 2002-02-28 2006-04-25 Smiths Medical Md, Inc. Cartridge and rod for axially loading medication pump
ATE363541T1 (de) 2002-03-26 2007-06-15 Lek Tovarna Farmacevtskih Verfahren für die herstellung eines gewünschten profils von erythropoietin glyko-isoformen
KR100954975B1 (ko) 2002-03-29 2010-04-30 구미아이 가가쿠 고교 가부시키가이샤 아세토락테이트 합성효소를 암호화하는 유전자
WO2003084477A2 (en) 2002-03-29 2003-10-16 Centocor, Inc. Mammalian cdr mimetibodies, compositions, methods and uses
US20040009902A1 (en) 2002-05-13 2004-01-15 Irving Boime CTP extended erythropoietin
EP2316922B1 (en) 2002-05-24 2013-05-22 Merck Sharp & Dohme Corp. Neutralizing human anti-IGFR antibody
US8034904B2 (en) 2002-06-14 2011-10-11 Immunogen Inc. Anti-IGF-I receptor antibody
US7538195B2 (en) 2002-06-14 2009-05-26 Immunogen Inc. Anti-IGF-I receptor antibody
EP1545608A4 (en) 2002-06-28 2006-09-13 Centocor Inc CH1-DELETED MAMMED MUICETIC BODIES, COMPOSITIONS, METHODS AND APPLICATIONS
CA2490411A1 (en) 2002-06-28 2004-01-08 Centocor, Inc. Mammalian epo mimetic ch1 deleted mimetibodies, compositions, methods and uses
AU2003246486A1 (en) 2002-07-19 2004-02-09 Cangene Corporation Pegylated erythropoietic compounds
WO2004018667A1 (ja) 2002-08-26 2004-03-04 Kirin Beer Kabushiki Kaisha ペプチド及びこれを含む医薬
SG2013096847A1 (en) 2002-09-06 2017-05-30 Medarex Llc Therapeutic human anti-il-1r1 monoclonal antibody
KR101045401B1 (ko) 2002-09-11 2011-06-30 프레제니우스 카비 도이치란트 게엠베하 하이드록시알킬 전분 유도체
AU2003278798A1 (en) 2002-09-12 2004-04-30 Children's Hospital Medical Center Method and device for painless injection of medication
US6919426B2 (en) 2002-09-19 2005-07-19 Amgen Inc. Peptides and related molecules that modulate nerve growth factor activity
US7396913B2 (en) 2002-10-14 2008-07-08 Abbott Laboratories Erythropoietin receptor binding antibodies
TWI320716B (en) 2002-10-14 2010-02-21 Abbott Lab Erythropoietin receptor binding antibodies
US20040071694A1 (en) 2002-10-14 2004-04-15 Devries Peter J. Erythropoietin receptor binding antibodies
US20040091961A1 (en) 2002-11-08 2004-05-13 Evans Glen A. Enhanced variants of erythropoietin and methods of use
WO2004058988A2 (en) 2002-12-20 2004-07-15 Amgen, Inc. Binding agents which inhibit myostatin
MXPA05009837A (es) 2003-03-14 2005-12-05 Pharmacia Corp Anticuerpos para el receptor del factor de crecimiento tipo insulina-i, para el tratamiento de canceres.
CA2519113C (en) 2003-04-02 2012-06-05 F. Hoffmann-La Roche Ag Antibodies against insulin-like growth factor i receptor and uses thereof
US7220410B2 (en) 2003-04-18 2007-05-22 Galaxy Biotech, Llc Monoclonal antibodies to hepatocyte growth factor
CA2524305C (en) 2003-05-01 2015-12-08 Imclone Systems Incorporated Fully human antibodies directed against the human insulin-like growth factor-1 receptor
TWI353991B (en) 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
EP1626983B8 (en) 2003-05-12 2010-12-22 Affymax, Inc. Novel poly (ethylene glycol) modified erythropoietin agonists and uses thereof
UA88146C2 (ru) 2003-05-12 2009-09-25 Афимакс, Инк. Новые пептиды, которые связываются с рецептором эритропоэтина
WO2004101611A2 (en) 2003-05-12 2004-11-25 Affymax, Inc. Peptides that bind to the erythropoietin receptor
US7074755B2 (en) 2003-05-17 2006-07-11 Centocor, Inc. Erythropoietin conjugate compounds with extended half-lives
WO2004108667A2 (en) 2003-05-30 2004-12-16 Centocor, Inc. Formation of novel erythropoietin conjugates using transglutaminase
DE10325106A1 (de) 2003-06-03 2004-12-30 Disetronic Licensing Ag Vorrichtung und Verfahren zur Erkennung eines Benutzers eines medizinischen Geräts
WO2005001136A1 (en) 2003-06-04 2005-01-06 Irm Llc Methods and compositions for modulating erythropoietin expression
WO2005000384A1 (en) 2003-06-05 2005-01-06 University Of Florida Auto-injection devices and methods for intramuscular administration of medications
MXPA05013437A (es) 2003-06-09 2007-08-24 Nipro Diabetes Systems Inc Sistema de acoplamiento para una bomba de infusion.
AR046071A1 (es) 2003-07-10 2005-11-23 Hoffmann La Roche Anticuerpos contra el receptor i del factor de crecimiento de tipo insulinico y los usos de los mismos
DK1648509T3 (da) 2003-07-15 2013-01-07 Amgen Inc Humane anti-NGF-neutraliserende antistoffer som selektive NGF-pathway-inhibitorer
KR101254371B1 (ko) 2003-07-18 2013-05-02 암젠 프레몬트 인코포레이티드 간세포 성장인자에 결합하는 분리된 항체
US20050019914A1 (en) 2003-07-24 2005-01-27 Aventis Pharma Deutschland Gmbh Perfusion process for producing erythropoietin
GB0317511D0 (en) 2003-07-25 2003-08-27 Biovex Ltd Viral vectors
EP1502613A1 (en) * 2003-08-01 2005-02-02 Novo Nordisk A/S Needle device with retraction means
ES2822181T3 (es) 2003-08-12 2021-04-29 Becton Dickinson Co Dispositivo de infusión a modo de parche
JP2007512001A (ja) 2003-08-28 2007-05-17 バイオレクシス ファーマシューティカル コーポレイション Ｅｐｏミメティックペプチドおよび融合タンパク質
CN1882355A (zh) 2003-09-09 2006-12-20 沃伦药品公司 保持内源性促红细胞生成素组织保护活性的长效促红细胞生成素
UA89481C2 (uk) 2003-09-30 2010-02-10 Центокор, Инк. Еритропоетинові міметичні шарнірно-серцевинні міметитіла людини, композиції, способи та застосування
US20060127404A1 (en) 2003-09-30 2006-06-15 Chichi Huang Hinge core mimetibodies, compositions, methods and uses
NZ547588A (en) 2003-11-07 2009-05-31 Immunex Corp Antibodies that bind interleukin-4 receptor
AR046639A1 (es) 2003-11-21 2005-12-14 Schering Corp Combinaciones terapeuticas de anticuerpo anti- igfr1
KR20060120141A (ko) 2003-11-24 2006-11-24 네오스 테크놀로지스, 인크. 글리코페질화 에리트로포이에틴
US8633157B2 (en) 2003-11-24 2014-01-21 Novo Nordisk A/S Glycopegylated erythropoietin
WO2005058967A2 (en) 2003-12-16 2005-06-30 Pierre Fabre Medicament Novel anti-insulin/igf-i hybrid receptor or anti-insulin/igf-i hybrid receptor and igf-ir antibodies and uses thereof
EP1548031A1 (en) 2003-12-22 2005-06-29 Dubai Genetics FZ-LLC Nature-identical erythropoietin
RU2370276C2 (ru) 2003-12-31 2009-10-20 Мерк Патент Гмбх Fc-ЭРИТРОПОЭТИН СЛИТЫЙ БЕЛОК С УЛУЧШЕННОЙ ФАРМАКОКИНЕТИКОЙ
CN1902311A (zh) 2003-12-31 2007-01-24 森托科尔公司 具有n－末端游离硫羟基的新的重组蛋白
US7423139B2 (en) 2004-01-20 2008-09-09 Insight Biopharmaceuticals Ltd. High level expression of recombinant human erythropoietin having a modified 5′-UTR
WO2005070451A1 (en) 2004-01-22 2005-08-04 Zafena Aktiebolag Pharmaceutical composition comprising non-glycosylated erythropoietin
WO2005084711A1 (en) 2004-03-02 2005-09-15 Chengdu Institute Of Biological Products A pegylated recombinant erythropoietin that has in vivo activity
TW200603818A (en) 2004-03-11 2006-02-01 Fresenius Kabi De Gmbh Conjugates of hydroxyethyl starch and erythropoietin
US20050227289A1 (en) 2004-04-09 2005-10-13 Reilly Edward B Antibodies to erythropoietin receptor and uses thereof
GB2413328A (en) 2004-04-23 2005-10-26 Cambridge Antibody Tech Erythropoietin protein variants
US7220245B2 (en) 2004-05-26 2007-05-22 Kriesel Marshall S Infusion apparatus
SI1781697T1 (sl) 2004-07-07 2009-08-31 Lundbeck & Co As H Novi karbamilirani epo in postopek za njegovo izdelavo
FR2873699B1 (fr) 2004-07-29 2009-08-21 Pierre Fabre Medicament Sa Nouveaux anticorps anti igf ir rt leurs utilisations
US20060073563A1 (en) 2004-09-02 2006-04-06 Xencor, Inc. Erythropoietin derivatives with altered immunogenicity
EP1805563B1 (en) 2004-10-28 2015-12-09 Hewlett-Packard Development Company, L.P. Adhesive primer coating for printing
WO2006050959A2 (en) 2004-11-10 2006-05-18 Aplagen Gmbh Molecules which promote hematopoiesis
MY146381A (en) 2004-12-22 2012-08-15 Amgen Inc Compositions and methods relating relating to anti-igf-1 receptor antibodies
EP1841455A1 (en) 2005-01-24 2007-10-10 Amgen Inc. Humanized anti-amyloid antibody
EP1843812A4 (en) * 2005-02-01 2008-12-03 Intelliject Llc DEVICES, SYSTEMS AND METHOD FOR DISPOSING MEDICAMENTS
US8147451B2 (en) 2005-02-11 2012-04-03 Stryker Corporation Reprogrammable fluid delivery system and method of use
US7592429B2 (en) 2005-05-03 2009-09-22 Ucb Sa Sclerostin-binding antibody
US7618393B2 (en) 2005-05-03 2009-11-17 Pharmajet, Inc. Needle-less injector and method of fluid delivery
CN101500597A (zh) 2005-06-17 2009-08-05 伊姆克罗尼系统公司 治疗转移性骨癌的受体拮抗剂
AU2006262335A1 (en) 2005-06-21 2007-01-04 Eli Lilly And Company Apparatus and method for injecting a pharmaceutical
WO2007000328A1 (en) 2005-06-27 2007-01-04 Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa Antibodies that bind to an epitope on insulin-like growth factor 1 receptor and uses thereof
CA2854576A1 (en) 2005-07-18 2007-01-25 Haichun Huang Human anti-b7rp1 neutralizing antibodies
FR2888850B1 (fr) 2005-07-22 2013-01-11 Pf Medicament Nouveaux anticorps anti-igf-ir et leurs applications
US20070038181A1 (en) 2005-08-09 2007-02-15 Alexander Melamud Method, system and device for delivering a substance to tissue
PE20071101A1 (es) 2005-08-31 2007-12-21 Amgen Inc Polipeptidos y anticuerpos
US7944366B2 (en) 2005-09-19 2011-05-17 Lifescan, Inc. Malfunction detection with derivative calculation
DE102005052502A1 (de) 2005-11-03 2007-05-16 Tecpharma Licensing Ag Autoinjektor-Aktivierung Auslöseelement
US20150057615A1 (en) 2005-11-08 2015-02-26 Asante Solutions Infusion Pump System
US8088096B2 (en) 2006-01-31 2012-01-03 Ares Trading S.A. Injection device with a capacitive proximity sensor
CA2641574C (en) 2006-02-09 2015-05-05 Deka Products Limited Partnership Patch-sized fluid delivery systems and methods
US9839743B2 (en) 2006-02-09 2017-12-12 Deka Products Limited Partnership Apparatus, system and method for fluid delivery
CN101405044B (zh) 2006-03-20 2013-10-16 诺沃-诺迪斯克有限公司 注射针位置的测定
TWI395754B (zh) 2006-04-24 2013-05-11 Amgen Inc 人類化之ｃ-ｋｉｔ抗體
US20070270744A1 (en) 2006-05-17 2007-11-22 Bruno Dacquay Limited Reuse Assembly For Ophthalmic Injection Device
RU2008150314A (ru) 2006-05-19 2010-06-27 Гликофи, Инк. (Us) Композиции эритропоэтина
US20070282269A1 (en) 2006-05-31 2007-12-06 Seattle Medical Technologies Cannula delivery apparatus and method for a disposable infusion device
US9308325B2 (en) 2006-06-19 2016-04-12 Corium International, Inc. Methods, devices, and kits for microjet drug delivery
CL2007002567A1 (es) 2006-09-08 2008-02-01 Amgen Inc Proteinas aisladas de enlace a activina a humana.
JP2010504798A (ja) 2006-09-29 2010-02-18 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 経皮ドラッグデリバリーのための電気的に活性化されたゲル配列
US20080234625A1 (en) 2006-10-16 2008-09-25 Bruno Dacquay Fuse Assembly For Single Use Medical Device
EP2083800A4 (en) 2006-10-19 2016-10-12 Ambu As DEVICE AND METHOD FOR PATIENT-ACTIVATED BOLUS ADMINISTRATION
WO2008133647A2 (en) 2006-11-07 2008-11-06 Merck & Co., Inc. Antagonists of pcsk9
CA2667869A1 (en) 2006-11-07 2008-05-15 Merck & Co., Inc. Antagonists of pcsk9
CN101636179B (zh) 2006-11-07 2012-10-10 默沙东公司 Pcsk9拮抗剂
CA2668131A1 (en) 2006-11-07 2008-05-15 Merck & Co., Inc. Antagonists of pcsk9
US7946985B2 (en) 2006-12-29 2011-05-24 Medtronic Minimed, Inc. Method and system for providing sensor redundancy
EP2136863A2 (en) 2007-03-19 2009-12-30 Insuline Medical Ltd. Device for drug delivery and associated connections thereto
CN101678168B (zh) * 2007-03-22 2013-03-06 特克法马许可公司 具有受控制的注射针拉回功能的注射装置
EP2137218A2 (en) 2007-04-13 2009-12-30 Novartis Ag Molecules and methods for modulating proprotein convertase subtilisin/kexin type 9 (pcsk9)
EP2144646A1 (en) 2007-05-10 2010-01-20 Medx-Set Ltd. Infusion set self-occlusion mechanism
US7981102B2 (en) 2007-05-21 2011-07-19 Asante Solutions, Inc. Removable controller for an infusion pump
US7794426B2 (en) 2007-05-21 2010-09-14 Asante Solutions, Inc. Infusion pump system with contamination-resistant features
WO2009013736A1 (en) 2007-07-20 2009-01-29 Medingo Ltd. Manually operable portable infusion device
US8683381B2 (en) 2007-08-09 2014-03-25 Alfred E. Mann Foundation For Scientific Research Drug delivery safety system
US20090082730A1 (en) 2007-09-24 2009-03-26 Li Nguyen Needle injection assembly
US8226606B2 (en) 2007-09-28 2012-07-24 Calibra Medical, Inc. Disposable infusion device with tactile dosage volume indicator
US7771391B2 (en) 2007-09-28 2010-08-10 Calibra Medical, Inc. Disposable infusion device with snap action actuation
US20090099525A1 (en) 2007-10-11 2009-04-16 Animas Corporation Drug Delivery System with Breakaway Plunger Extractor
JP2011501952A (ja) 2007-10-26 2011-01-20 シェーリング コーポレイション 脂質障害およびコレステロール障害を治療するための抗ｐｃｓｋ９および方法
US7875022B2 (en) 2007-12-12 2011-01-25 Asante Solutions, Inc. Portable infusion pump and media player
US7976505B2 (en) 2007-12-19 2011-07-12 Calibra Medical, Inc. Disposable infusion device negative pressure filling apparatus and method
US10188787B2 (en) 2007-12-31 2019-01-29 Deka Products Limited Partnership Apparatus, system and method for fluid delivery
US20090177142A1 (en) 2008-01-09 2009-07-09 Smiths Medical Md, Inc Insulin pump with add-on modules
AR070315A1 (es) 2008-02-07 2010-03-31 Merck & Co Inc Anticuerpos 1b20 antagonistas de pcsk9
AR070316A1 (es) 2008-02-07 2010-03-31 Merck & Co Inc Antagonistas de pcsk9 (proproteina subtilisina-kexina tipo 9)
US8540673B2 (en) 2008-03-18 2013-09-24 Calibra Medical, Inc. Disposable infusion device with actuation lock-out
US7976500B2 (en) 2008-06-26 2011-07-12 Calibra Medical, Inc. Disposable infusion device with redundant valved safety
US8231577B2 (en) 2008-06-26 2012-07-31 Calibra Medical, Inc. Disposable infusion device with automatically releasable cannula driver
US8361030B2 (en) 2008-06-26 2013-01-29 Calibra Medical, Inc. Disposable infusion device with occlusion detector
GB0814747D0 (en) * 2008-08-13 2008-09-17 Owen Mumford Ltd Autoinjection devices
ES2498741T3 (es) 2008-09-10 2014-09-25 F. Hoffmann-La Roche Ag Dispositivo de administración para uso con un fármaco terapéutico
TWI516501B (zh) 2008-09-12 2016-01-11 禮納特神經系統科學公司 Ｐｃｓｋ９拮抗劑類
US8262616B2 (en) 2008-10-10 2012-09-11 Deka Products Limited Partnership Infusion pump assembly
US8016789B2 (en) 2008-10-10 2011-09-13 Deka Products Limited Partnership Pump assembly with a removable cover assembly
US8223028B2 (en) 2008-10-10 2012-07-17 Deka Products Limited Partnership Occlusion detection system and method
US20100121274A1 (en) 2008-11-12 2010-05-13 Baxter International Inc. Prefillable constant pressure ambulatory infusion pump
JO3672B1 (ar) 2008-12-15 2020-08-27 Regeneron Pharma أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9).
US9370621B2 (en) 2008-12-16 2016-06-21 Medtronic Minimed, Inc. Needle insertion systems and methods
JO3382B1 (ar) 2008-12-23 2019-03-13 Amgen Inc أجسام مضادة ترتبط مع مستقبل cgrp بشري
WO2010107761A1 (en) 2009-03-18 2010-09-23 Acelrx Pharmaceuticals, Inc. Improved storage and dispensing devices for administration of oral transmucosal dosage forms
US7976493B2 (en) 2009-05-05 2011-07-12 Calibra Medical, Inc. Disposable infusion device with resettable last dose lock-out
US8344847B2 (en) 2009-07-09 2013-01-01 Medtronic Minimed, Inc. Coordination of control commands in a medical device system having at least one therapy delivery device and at least one wireless controller device
US8932256B2 (en) 2009-09-02 2015-01-13 Medtronic Minimed, Inc. Insertion device systems and methods
US10071198B2 (en) 2012-11-02 2018-09-11 West Pharma. Servicees IL, Ltd. Adhesive structure for medical device
ES2393278T3 (es) * 2009-09-25 2012-12-20 Carebay Europe Limited Dispositivo de administración médica
US20120219558A1 (en) 2009-09-25 2012-08-30 Yan Ni Antagonists of pcsk9
CN104474606B (zh) 2009-10-13 2017-04-26 瓦莱里塔斯公司 流体输送装置
US7967773B2 (en) 2009-10-13 2011-06-28 Smiths Medical Asd, Inc. Two piece medication cassette closure apparatus and method
US8877900B2 (en) 2009-10-30 2014-11-04 Merck Sharp & Dohme Corp. AX132 PCSK9 antagonists
JP2013509191A (ja) 2009-10-30 2013-03-14 メルク・シャープ・エンド・ドーム・コーポレイション Ａｘ１およびａｘ１８９ｐｃｓｋ９アンタゴニストおよびバリアント
US8449504B2 (en) 2009-11-11 2013-05-28 Calibra Medical, Inc. Wearable infusion device and system
AR079336A1 (es) 2009-12-11 2012-01-18 Irm Llc Antagonistas de la pro-proteina convertasa-subtilisina/quexina tipo 9 (pcsk9)
DK3527239T3 (da) 2009-12-16 2021-04-26 Becton Dickinson Co Selvinjektionsindretning
WO2011075100A1 (en) 2009-12-16 2011-06-23 Becton, Dickinson And Company Self-injection device
WO2011075105A1 (en) 2009-12-16 2011-06-23 Becton, Dickinson And Company Self-injection device
DK2512579T3 (en) 2009-12-16 2017-03-13 Becton Dickinson Co Self Injection Device
WO2011075102A1 (en) 2009-12-16 2011-06-23 Becton, Dickinson And Company Self- injection device
US8070723B2 (en) 2009-12-31 2011-12-06 Medtronic Minimed, Inc. Activity guard
WO2011082370A1 (en) 2009-12-31 2011-07-07 Abbott Diabetes Care Inc. Injection port device adapted for use with insulin pump
EP2525844B1 (en) * 2010-01-22 2017-12-20 DEKA Products Limited Partnership Infusion pump system comprising temperature compensation for adjusting infusion rate
EP2536451B1 (en) * 2010-02-18 2018-03-28 Sanofi-Aventis Deutschland GmbH Auto-injector with a torsion spring
CA2790912A1 (en) 2010-02-25 2011-09-01 Lifescan Scotland Limited Analyte testing method and system with safety warnings for insulin dosing
WO2011111007A2 (en) 2010-03-11 2011-09-15 Rinat Neuroscience Corporation ANTIBODIES WITH pH DEPENDENT ANTIGEN BINDING
AU2011242602B2 (en) 2010-04-21 2015-06-18 Abbvie Biotechnology Ltd Wearable automatic injection device for controlled delivery of therapeutic agents
US8821454B2 (en) 2010-05-12 2014-09-02 Bioquiddity, Inc. Apparatus for dispensing medicinal fluids and method of making same
US9737659B2 (en) 2010-05-12 2017-08-22 Bioq Pharma Incorporated Apparatus for dispensing medicinal fluids and method of making same
MX2012014180A (es) * 2010-06-07 2013-05-06 Amgen Inc Dispositivo de administracion de farmacos.
WO2012032411A2 (en) 2010-09-07 2012-03-15 Tecpharma Licensing Ag Automatic injection device
US9498573B2 (en) 2010-09-24 2016-11-22 Perqflo, Llc Infusion pumps
US9216249B2 (en) 2010-09-24 2015-12-22 Perqflo, Llc Infusion pumps
US9381300B2 (en) 2010-09-24 2016-07-05 Perqflo, Llc Infusion pumps
US8915879B2 (en) 2010-09-24 2014-12-23 Perqflo, Llc Infusion pumps
EP2438945A1 (en) * 2010-10-08 2012-04-11 Sanofi-Aventis Deutschland GmbH Reusable engine for an auto-injector
US9211378B2 (en) 2010-10-22 2015-12-15 Cequr Sa Methods and systems for dosing a medicament
WO2012054438A1 (en) 2010-10-22 2012-04-26 Schering Corporation Anti-pcsk9
US9750898B2 (en) 2010-11-03 2017-09-05 Sanofi-Aventis Deutschland Gmbh Medicated module with interlock
US8905972B2 (en) 2010-11-20 2014-12-09 Perqflo, Llc Infusion pumps
GB201020475D0 (en) 2010-12-02 2011-01-19 Oval Medical Technologies Ltd Delivery mechanism for an autoinjector
EA201390929A1 (ru) 2010-12-22 2013-12-30 Дженентек, Инк. Антитела к pcsk9 и способы их применения
MX366458B (es) 2011-01-28 2019-07-10 Sanofi Biotechnology Composiciones farmaceuticas que comprenden anticuerpos humanos frente a pcsk9.
AU2012214251A1 (en) 2011-02-11 2013-09-12 Novartis Ag PCSK9 antagonists
MX345747B (es) * 2011-04-21 2017-02-14 Abbvie Inc Dispositivo de inyección automático portable.
US9821116B2 (en) 2011-07-25 2017-11-21 Preciflex Sa Fluid dispenser
CN103764200B (zh) 2011-09-02 2016-12-21 尤尼特拉克特注射器控股有限公司 用于具有积体式状态指示的药品输送帮浦的驱动机构
US9814832B2 (en) * 2011-09-02 2017-11-14 Unl Holdings Llc Drive mechanism for drug delivery pumps with integrated status indication
WO2013029999A1 (en) 2011-09-02 2013-03-07 F. Hoffmann-La Roche Ag Dosing unit for an ambulatory infusion device
US9707335B2 (en) * 2011-09-02 2017-07-18 Unitract Syringe Pty Ltd Drive mechanism for drug delivery pumps with integrated status indication
WO2013030000A1 (en) 2011-09-02 2013-03-07 F. Hoffmann-La Roche Ag Dosing unit for an ambulatory infusion device
CA2848242C (en) 2011-09-09 2019-12-24 Merck Patent Gmbh Reloadable auto-injector
JP6424089B2 (ja) 2011-11-07 2018-11-14 イーライ リリー アンド カンパニー 人間工学的改善を施した注射器具
DE102011119000A1 (de) 2011-11-21 2013-05-23 Liebherr-Verzahntechnik Gmbh Verzahnmaschine und Verfahren zur Herstellung oder Bearbeitung von Verzahnungen
JP2014533539A (ja) 2011-11-22 2014-12-15 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング その駆動のためのコントローラと時間ロックアウト機構とを備えたペン型薬物注射デバイス
WO2013114221A2 (en) 2012-01-31 2013-08-08 Preciflex Sa Injection device using dry carrier
WO2013115843A1 (en) 2012-01-31 2013-08-08 Medimop Medical Projects Ltd. Time dependent drug delivery apparatus
EP2628494A1 (en) 2012-02-17 2013-08-21 Sensile Pat AG Liquid storage and delivery system
WO2013127428A1 (en) 2012-02-27 2013-09-06 F. Hoffmann-La Roche Ag Spring force assembly for biasing or actuating stoppers of syringes, injection pen cartridges and the like
US9072827B2 (en) 2012-03-26 2015-07-07 Medimop Medical Projects Ltd. Fail safe point protector for needle safety flap
EP2836261B1 (en) 2012-04-13 2020-01-15 Becton, Dickinson and Company Infusion device with safety feature for preventing inadvertent activation
US9335910B2 (en) 2012-04-23 2016-05-10 Tandem Diabetes Care, Inc. System and method for reduction of inadvertent activation of medical device during manipulation
US9715327B2 (en) 2012-06-07 2017-07-25 Tandem Diabetes Care, Inc. Preventing inadvertent changes in ambulatory medical devices
EP2674179A1 (en) 2012-06-15 2013-12-18 Ares Trading S.A. Injection device
US8454557B1 (en) 2012-07-19 2013-06-04 Asante Solutions, Inc. Infusion pump system and method
WO2014022053A1 (en) 2012-07-31 2014-02-06 Nipro Healthcare Systems, Llc. Device and method for dispensing fluid from an infusion pump
WO2014025796A2 (en) 2012-08-06 2014-02-13 Minipumps, Llc. Piston pump devices
US9867929B2 (en) 2012-08-15 2018-01-16 Becton, Dickinson And Company Pump engine with metering system for dispensing liquid medication
US20140088508A1 (en) 2012-09-24 2014-03-27 Patrick Ryan Drug-delivery devices with integrated needle-insertion mechanism
US9782538B2 (en) 2012-09-27 2017-10-10 Becton, Dickinson And Company Angled inserter for drug infusion
EP2716317A1 (en) 2012-10-04 2014-04-09 Sanofi-Aventis Deutschland GmbH Medicament delivery device with trigger button
US9789250B2 (en) 2012-10-05 2017-10-17 Becton, Dickinson And Company Infusion set with safety device
GB201218913D0 (en) 2012-10-22 2012-12-05 Ucb Pharma Sa Auto-injector and drive unit therefor
JP6205701B2 (ja) 2012-10-22 2017-10-04 セイコーエプソン株式会社 流体注入装置
JP2014087449A (ja) 2012-10-30 2014-05-15 Seiko Epson Corp 液体輸送装置及びカテーテルの抜け判定方法
US9987436B2 (en) * 2012-12-21 2018-06-05 Carebay Europe Ltd Medicament delivery device
WO2014106056A2 (en) 2012-12-27 2014-07-03 Kaleo, Inc. Devices, systems and methods for locating and interacting with medicament delivery systems
DE202013000411U1 (de) 2013-01-16 2013-01-24 H & B Electronic Gmbh & Co. Kg Dauerinfusionsvorrichtung
CA2899370A1 (en) 2013-01-25 2014-07-31 Unitract Syringe Pty Ltd Fluid restriction mechanisms for drug delivery pumps
HK1217924A1 (zh) 2013-01-25 2017-01-27 Unitract Syringe Pty Ltd 用於药物输送泵的整体式的滑动密封流体通道连接件和药物容器
PL2764881T3 (pl) 2013-02-06 2018-02-28 Medirio Sa System leczenia medycznego
US9446186B2 (en) 2013-03-01 2016-09-20 Bigfoot Biomedical, Inc. Operating an infusion pump system
US20140276423A1 (en) 2013-03-14 2014-09-18 Tandem Diabetes Care, Inc. Infusion system and methods
US9889252B2 (en) 2013-06-14 2018-02-13 Medtronic, Inc. Infusion device assembly
US20150005703A1 (en) 2013-06-28 2015-01-01 Animas Corporation Drug infusion device with safety interlock
EP2865325B1 (en) 2013-10-23 2017-11-22 F. Hoffmann-La Roche AG Skin-adherable cradle for infusion pump or continuous blood glucose monitor having optical indication means
US20150182688A1 (en) 2013-12-31 2015-07-02 Abbvie Inc. Devices and methods for delivering a beneficial agent to a user
US10195342B2 (en) 2014-04-24 2019-02-05 Becton, Dickinson And Company Cannula deployment mechanism
EP3848072A1 (en) 2014-12-19 2021-07-14 Amgen Inc. Drug delivery device with proximity sensor

Also Published As

Publication number Publication date
US10765801B2 (en) 2020-09-08
ES2898469T3 (es) 2022-03-07
JP7049395B2 (ja) 2022-04-06
US20200353160A1 (en) 2020-11-12
US20170361015A1 (en) 2017-12-21
EP3233163A1 (en) 2017-10-25
JP7049394B2 (ja) 2022-04-06
US20160175515A1 (en) 2016-06-23
JP2017538511A (ja) 2017-12-28
JP7371158B2 (ja) 2023-10-30
EP3233163B1 (en) 2021-10-13
JP2020151506A (ja) 2020-09-24
US20240245865A1 (en) 2024-07-25
US12415039B2 (en) 2025-09-16
JP2020151507A (ja) 2020-09-24
JP2022084835A (ja) 2022-06-07
US10799630B2 (en) 2020-10-13
US11944794B2 (en) 2024-04-02
US20160175527A1 (en) 2016-06-23
EP3848072A1 (en) 2021-07-14
WO2016100781A1 (en) 2016-06-23

Similar Documents

Publication Publication Date Title
JP7371158B2 (ja) 近接センサ付き薬物送達装置
US20230372607A1 (en) Drug delivery device with sterile fluid flowpath and related method of assembly
US11813426B2 (en) Drug delivery device including seal member for needle of syringe
EP3691717B1 (en) Flow adapter for drug delivery device
US12318593B2 (en) Hydraulic-pneumatic pressurized chamber drug delivery system
US11369736B2 (en) Cannula insertion and retraction mechanisms
US11103636B2 (en) Needle insertion mechanism for drug delivery device
US11571511B2 (en) Insertion mechanism and method of inserting a needle of a drug delivery device
EP3694578B1 (en) Drug delivery device with drive assembly and related method of assembly
US12329944B2 (en) Drug delivery device having pressurized vessel
JP2025179199A (ja) 調整可能な注入時間を有する薬物送達システム及び使用方法

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20181022

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20181022

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20190820

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20190816

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20191119

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20200512

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20200610

R150 Certificate of patent or registration of utility model

Ref document number: 6716566

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250