JP6463359B2 - 補体関連病態を治療するための組成物及び方法 - Google Patents

補体関連病態を治療するための組成物及び方法 Download PDF

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JP6463359B2
JP6463359B2 JP2016533496A JP2016533496A JP6463359B2 JP 6463359 B2 JP6463359 B2 JP 6463359B2 JP 2016533496 A JP2016533496 A JP 2016533496A JP 2016533496 A JP2016533496 A JP 2016533496A JP 6463359 B2 JP6463359 B2 JP 6463359B2
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snp
allele
polymorphism
seq
antibody
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JP2016537006A (ja
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ブライアン ヤスパン，
ブライアン ヤスパン，
ロバート ロイヤル グレアム，
ロバート ロイヤル グレアム，
エイミー ドレッセン，
エイミー ドレッセン，
チョンロン リー，
チョンロン リー，
エーリヒ シュトラウス，
エーリヒ シュトラウス，
テオドリカ ブガワン，
テオドリカ ブガワン，
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Genentech Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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  • Investigating Or Analysing Biological Materials (AREA)
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JP2016533496A 2013-08-12 2014-08-11 補体関連病態を治療するための組成物及び方法 Expired - Fee Related JP6463359B2 (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201361864941P 2013-08-12 2013-08-12
US61/864,941 2013-08-12
US201361866651P 2013-08-16 2013-08-16
US61/866,651 2013-08-16
US201361872098P 2013-08-30 2013-08-30
US61/872,098 2013-08-30
US201461988012P 2014-05-02 2014-05-02
US61/988,012 2014-05-02
US201462021487P 2014-07-07 2014-07-07
US62/021,487 2014-07-07
PCT/US2014/050579 WO2015023596A1 (en) 2013-08-12 2014-08-11 Compositions and method for treating complement-associated conditions

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JP6463359B2 true JP6463359B2 (ja) 2019-01-30

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JP2017222267A Withdrawn JP2018064566A (ja) 2013-08-12 2017-09-28 補体関連病態を治療するための組成物及び方法
JP2019154149A Pending JP2020028293A (ja) 2013-08-12 2019-07-30 補体関連病態を治療するための組成物及び方法

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EP (1) EP3033436A1 (cg-RX-API-DMAC7.html)
JP (3) JP6463359B2 (cg-RX-API-DMAC7.html)
KR (2) KR20180021234A (cg-RX-API-DMAC7.html)
CN (1) CN107318267B (cg-RX-API-DMAC7.html)
AU (1) AU2014306867B2 (cg-RX-API-DMAC7.html)
BR (1) BR112016002845A2 (cg-RX-API-DMAC7.html)
CA (1) CA2920666A1 (cg-RX-API-DMAC7.html)
CL (1) CL2016000326A1 (cg-RX-API-DMAC7.html)
CR (1) CR20160132A (cg-RX-API-DMAC7.html)
EA (1) EA201690213A1 (cg-RX-API-DMAC7.html)
IL (1) IL243928A0 (cg-RX-API-DMAC7.html)
MX (1) MX2016001854A (cg-RX-API-DMAC7.html)
PE (1) PE20160192A1 (cg-RX-API-DMAC7.html)
PH (1) PH12016500302A1 (cg-RX-API-DMAC7.html)
SG (1) SG11201601044XA (cg-RX-API-DMAC7.html)
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Cited By (1)

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JP2020028293A (ja) * 2013-08-12 2020-02-27 ジェネンテック， インコーポレイテッド 補体関連病態を治療するための組成物及び方法

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CN108472382A (zh) 2015-10-30 2018-08-31 豪夫迈·罗氏有限公司 抗-因子d抗体变体缀合物及其用途
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CN108289951A (zh) 2015-10-30 2018-07-17 豪夫迈·罗氏有限公司 抗-因子d抗体和缀合物
CN106885910B (zh) * 2015-12-15 2018-12-21 上海吉涛生物科技有限公司 肿瘤易感微环境检测装置及试剂盒
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CN109706238B (zh) * 2017-10-26 2023-04-07 珠海岐微生物科技有限公司 一种老年性黄斑病变的检测与治疗方法
TWI831792B (zh) * 2018-06-12 2024-02-11 合一生技股份有限公司 靶向淋巴細胞活化基因3(lag-3)的核酸適體及其用途
CN109243567B (zh) * 2018-08-14 2021-11-02 山东科技大学 一种基于处方数据挖掘的药物推荐方法
CN109448781B (zh) * 2018-11-06 2021-09-14 云南大学 一种流感病毒抗原变化的预测方法
WO2020098630A1 (en) 2018-11-14 2020-05-22 Zhuhai Qiwei Bio-Technology Ltd. Animal models, screening methods, and treatment methods for intraocular diseases or disorders
EP3990433A4 (en) 2019-06-25 2023-07-26 Translatum Medicus Inc. METHODS FOR THE MANUFACTURE OF 2-((1-BENZYL-1H-INDAZOL-3-YL)METHOXY)-2-METHYLPROPANOIC ACID AND ITS DERIVATIVES
CN114395620B (zh) * 2021-12-20 2022-09-20 温州谱希医学检验实验室有限公司 一种检测高度近视易感人群的生物标志物组合
CN117235479A (zh) * 2023-08-25 2023-12-15 上海金仕达软件科技股份有限公司 目标因子筛选方法及装置

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