JP6415979B2 - ヒドラジノ1h−イミダゾキノリン−4−アミン及びこれから調製された複合体 - Google Patents

ヒドラジノ1h−イミダゾキノリン−4−アミン及びこれから調製された複合体 Download PDF

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JP6415979B2
JP6415979B2 JP2014513746A JP2014513746A JP6415979B2 JP 6415979 B2 JP6415979 B2 JP 6415979B2 JP 2014513746 A JP2014513746 A JP 2014513746A JP 2014513746 A JP2014513746 A JP 2014513746A JP 6415979 B2 JP6415979 B2 JP 6415979B2
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JP2014515406A5 (OSRAM
JP2014515406A (ja
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ディー.ワイトマン ポール
ディー.ワイトマン ポール
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3M Innovative Properties Co
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
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    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
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    • A61K47/646Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
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    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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  • Nitrogen Condensed Heterocyclic Rings (AREA)
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JP2014513746A 2011-06-03 2012-06-01 ヒドラジノ1h−イミダゾキノリン−4−アミン及びこれから調製された複合体 Active JP6415979B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161493051P 2011-06-03 2011-06-03
US201161493143P 2011-06-03 2011-06-03
US61/493,143 2011-06-03
US61/493,051 2011-06-03
PCT/US2012/040461 WO2012167081A1 (en) 2011-06-03 2012-06-01 Hydrazino 1h-imidazoquinolin-4-amines and conjugates made therefrom

Related Child Applications (1)

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JP2017078814A Division JP6430574B2 (ja) 2011-06-03 2017-04-12 ヒドラジノ1h−イミダゾキノリン−4−アミン及びこれから調製された複合体

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JP2014515406A JP2014515406A (ja) 2014-06-30
JP2014515406A5 JP2014515406A5 (OSRAM) 2015-07-23
JP6415979B2 true JP6415979B2 (ja) 2018-10-31

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JP2014513746A Active JP6415979B2 (ja) 2011-06-03 2012-06-01 ヒドラジノ1h−イミダゾキノリン−4−アミン及びこれから調製された複合体
JP2017078814A Expired - Fee Related JP6430574B2 (ja) 2011-06-03 2017-04-12 ヒドラジノ1h−イミダゾキノリン−4−アミン及びこれから調製された複合体
JP2017078817A Pending JP2017160220A (ja) 2011-06-03 2017-04-12 ポリエチレングリコールセグメントを有するヘテロ2官能性リンカー及び該リンカーから調製された免疫反応調節複合体

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JP2017078817A Pending JP2017160220A (ja) 2011-06-03 2017-04-12 ポリエチレングリコールセグメントを有するヘテロ2官能性リンカー及び該リンカーから調製された免疫反応調節複合体

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US (3) US9107958B2 (OSRAM)
EP (3) EP3366311B1 (OSRAM)
JP (3) JP6415979B2 (OSRAM)
CN (1) CN103582640B (OSRAM)
AU (1) AU2012261959B2 (OSRAM)
BR (1) BR112013031039B1 (OSRAM)
CA (1) CA2838023C (OSRAM)
MX (1) MX355623B (OSRAM)
WO (1) WO2012167081A1 (OSRAM)
ZA (1) ZA201309687B (OSRAM)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8871782B2 (en) 2003-10-03 2014-10-28 3M Innovative Properties Company Alkoxy substituted imidazoquinolines
US8541438B2 (en) 2004-06-18 2013-09-24 3M Innovative Properties Company Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
WO2012024284A1 (en) 2010-08-17 2012-02-23 3M Innovative Properties Company Lipidated immune response modifier compound compositions, formulations, and methods
JP6460789B2 (ja) * 2011-06-03 2019-01-30 スリーエム イノベイティブ プロパティズ カンパニー ポリエチレングリコールセグメントを有するヘテロ2官能性リンカー及び該リンカーから調製された免疫反応調節複合体
JP6415979B2 (ja) * 2011-06-03 2018-10-31 スリーエム イノベイティブ プロパティズ カンパニー ヒドラジノ1h−イミダゾキノリン−4−アミン及びこれから調製された複合体
EP2968239B1 (en) 2013-03-14 2019-04-24 The University of Massachusetts Methods of inhibiting cataracts and presbyopia
US9642895B2 (en) 2013-08-12 2017-05-09 3M Innovative Properties Company Peptides for enhancing transdermal delivery
RU2687279C2 (ru) 2013-11-05 2019-05-13 3М Инновейтив Пропертиз Компани Инъекционные композиции на основе кунжутного масла
PL3134402T3 (pl) 2014-04-22 2020-11-02 F.Hoffmann-La Roche Ag Związki 4-amino-imidazochinolinowe
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