JP6170494B2 - ピロロベンゾジアゼピン - Google Patents

ピロロベンゾジアゼピン Download PDF

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JP6170494B2
JP6170494B2 JP2014531224A JP2014531224A JP6170494B2 JP 6170494 B2 JP6170494 B2 JP 6170494B2 JP 2014531224 A JP2014531224 A JP 2014531224A JP 2014531224 A JP2014531224 A JP 2014531224A JP 6170494 B2 JP6170494 B2 JP 6170494B2
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JP2014527974A5 (https=
JP2014527974A (ja
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フィリップ・ウィルソン・ハワード
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MedImmune Ltd
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MedImmune Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
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  • Animal Behavior & Ethology (AREA)
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  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
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  • Molecular Biology (AREA)
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  • Diabetes (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
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  • Heart & Thoracic Surgery (AREA)
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JP2014531224A 2011-09-20 2012-09-20 ピロロベンゾジアゼピン Expired - Fee Related JP6170494B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161536669P 2011-09-20 2011-09-20
US61/536,669 2011-09-20
PCT/EP2012/068506 WO2013041606A1 (en) 2011-09-20 2012-09-20 Pyrrolobenzodiazepines as unsymmetrical dimeric pbd compounds for inclusion in targeted conjugates

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JP2014527974A JP2014527974A (ja) 2014-10-23
JP2014527974A5 JP2014527974A5 (https=) 2015-11-12
JP6170494B2 true JP6170494B2 (ja) 2017-07-26

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US9399641B2 (en) 2016-07-26
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BR112014006703A8 (pt) 2018-01-09
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US20150158869A1 (en) 2015-06-11
MX2014003349A (es) 2015-04-10
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CA2849039C (en) 2018-09-18
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