JP6043043B2 - 皮膚、特に、デコルタージュ治療用の組成物、キット、及びレジメン - Google Patents
皮膚、特に、デコルタージュ治療用の組成物、キット、及びレジメン Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/362—Polycarboxylic acids
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- A61K8/602—Glycosides, e.g. rutin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/88—Two- or multipart kits
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Description
本出願は、2008年1月4日出願の米国特許仮出願第61/019,047号、及び2008年12月10日出願の米国実用新案出願第12/331,781号に基づく優先権を主張するものである。
多金属錯体含有組成物としては、局所的に許容される担体及び少なくとも1つの多金属錯体が挙げられる。多金属錯体は、多官能性化合物(実施形態では、多官能性酸、又はアミノ酸)と2つ以上の異なる配位元素の反応生成物であり、同一分子中に少なくとも2つの異なる金属カチオンを有する化合物を生じる。
実施形態では、マロン酸を水溶液中で銅及び亜鉛成分を含有する化合物と反応させる。マロン酸:銅成分:亜鉛成分は少なくとも約3:1:1のモル比で存在させた場合に、マロン酸銅−亜鉛が高収率且つ高結晶純度で得られることが判った。
マロン酸は1,3−プロパン二酸とも称し、CH2(COOH)2の構造をもつジカルボン酸、即ち、
同一分子内に少なくとも2つの金属カチオンを有する得られた化合物は、ここに記載されている皮膚の治療レジメンに使用される多金属錯体含有組成物中の有効成分として機能する。そのような有効成分は、多くの原料成分と組み合わせることによって多くの化学用途、例えば、触媒剤、ポリマーの架橋剤、超伝導電気材料、医薬品、補助食品等の製品を形成する。適当な組成物中の有効成分は、ヒトや他の哺乳動物の皮膚、或いは他の組織に局所的に塗布することができる。そのような製品としては、皮膚科学的又は薬学的に許容される担体、賦形剤、又は媒体、例えば、塗布する組織と適合する担体、賦形剤、又は媒体を挙げることができる。本明細書で使用する「皮膚科学的又は薬学的に許容される」なる語は、そのように記載されている組成物又はその成分が、一般的に、過度の毒性、不適合性、不安定性、アレルギー反応等がなく、これらの組織と接触して使用する、或いは患者に使用するのに適当であることを意味している。実施形態では、本開示による組成物は、化粧品及び/又は皮膚科で従来使用されている任意の原料成分を含むことができる。実施形態では、有効成分は、溶液中で結晶のみならず、固形をもたらすように調合される。
**ニュージャージー州イスリン所在のEngelhard Corporationから市販のFlamenco Satin Green P860;ニュージャージー州サウスプレーンフィールド所在のKobo Productsから市販のKobo BPD 500、及び/又は、ニュージャージー州サマセット所在のPresperse Inc.から市販のCloverleaf AR−80として存在する場合もある。
多金属錯体含有組成物の塗布に先立ち、レチノイドとヒドロキノンの両方を塗布することで本レジメンに従って皮膚を治療する。レチノイドは、レチノイド、及び皮膚科学的又は薬学的に許容される担体を含有する組成物として塗布することができる。
本発明の治療レジメンで使用するのに適当なヒドロキノン組成物としては、限定的ではないが、例えば、GLYTONE(登録商標)Fading Lotion(2% HQ)、La Roche−PosayによるMELA−D(登録商標)、ExuvianceによるESSENTIAL SKIN LIGHTENER(登録商標)、PCA SKINによるPIGMENT GEL−Phaze 13(登録商標)、Physician’s Complexによる6% SKIN BLEACHING CREAM、BiomedicによるCONDITIONING GEL PLUS、pH AdvantageによるPIGMENTAION FADER、LumediaによるLUMEDIA、Peter Thomas RothによるPOTENT SKIN LIGHTENING GEL COMPLEX、NeoStrataによるHQ SKIN LIGHTENING GEL PHA、B.KaminsによるSKIN LIGHTENING TREATMENTなどの市販製品が挙げられる。
式中、Rは、ヒドロキノンの美白機能性を維持し、かつ、ユーザ皮膚の局所塗布に適当な非毒性化合物をもたらす基である。
本開示によるデコルタージュの治療レジメンは、レチノイド及びヒドロキノンをデコルタージュに順次塗布した後に多金属錯体含有組成物を塗布することを含む。レチノイド及び/又はヒドロキノンを塗布する前に多金属錯体を塗布してもよいことは当然理解されるべきである。
マロン酸(CH2(COOH)2)1.8gを塩基性炭酸銅(CuCO3・Cu(OH)2)0.632g、炭酸亜鉛(3Zn(OH)2・2ZnCO3)0.676g、及び水100mlと混合し、分散液を生成した。この溶液を反応物が溶液に溶けるまで加熱した。くっきりとした深青色結晶が沈殿し、室温で保持していたマロン酸、塩基性炭酸銅、及び炭酸亜鉛(3:1:1のモル比)の水溶液から分離した。同一分子中で酸性基を銅及び亜鉛カチオンに置換することで二重塩を生成した。深青色結晶は、約210℃の融点をもつことが分かった。
マロン酸(CH2(COOH)2)1.8gを塩基性炭酸銅(CuCO3・Cu(OH)2)0.632g、炭酸亜鉛(3Zn(OH)2・2ZnCO3)0.676g、及び熱湯100mlと混合した。室温で一週間保持しておいたマロン酸、塩基性炭酸銅、及び炭酸亜鉛(3:1:1のモル比)の水溶液からくっきりとした深青色結晶を分離した。
熱湯100ml(およそ95〜100℃)を含有する撹拌反応槽内で、マロン酸3モルを(炭酸第二銅として)銅1モル及び(炭酸亜鉛として)亜鉛1モルと完全に混合した。冷却しながら短い反応時間の後、マロン酸銅−亜鉛が高収率で溶液から沈殿した。濾過工程を用いて、粉末剤として錯体を単離した。融点が約210℃の深青色結晶を得た。
以下の表5に示した量で記載の原料成分を有する多金属錯体含有組成物を調製する。
2ニュージャージー州サマセット所在のPresperse Inc.から市販のPermethyl 101A
3ペンシルベニア州アンブラー所在のCognis Chemicalから市販のCetiol LC
4ニュージャージー州サマセット所在のPresperse Inc.から市販のGemseal 25
5ニュージャージー州パターソン所在のLipo Chemicals,Inc.から市販
6ニュージャージー州イスリン所在のEngelhard Corporationから市販
7ニュージャージー州サウスプレーンフィールド所在のKobo Productsから市販
8ニュージャージー州サマセット所在のPresperse Inc.から市販
本開示による治療レジメンの耐容性を評価するためランダム化比較試験を行った。治療レジメンには、実施例7の組成物、市販の2%ヒドロキノン及びトレチノイン含有OBAGI NU−DERM(登録商標)BLENDER(登録商標)を0.025%又は0.05%のいずれかで塗布することを含めた。40〜60歳の女性40人が試験に参加し、対象者の半分には0.025%トレチノインを使用し、残りの半分には0.05%トレチノインを使用した。対象者自身(自己評価)により、及び後述する治療を適用した熟練医師によって耐容性を評価した。
1)「10セント」サイズの量のヒドロキノン含有配合物と、「10セント」サイズの量のトレチノインを絞り取って手のひらに乗せ、指先で一緒に混合した。次に、反対の手の指先を用いて、プレミックス製品をデコルタージュに均一に塗布し、製品を首までフェザーリングして終えた。
2)2ポンプ分の多金属錯体含有組成物を手のひらに注出した。反対の手の指先を用いて、製品全量をデコルタージュに塗布し、製品を首までたっぷりとフェザーリングして終えた。
3)治療システム製品を塗布した後に手を洗い、眼や口に触れないように注意した。
1)「10セント」サイズの量のヒドロキノン含有配合物を指先に絞り取ってデコルタージュに均一に塗布し、製品を首までフェザーリングして終えた。
2)2ポンプ分の多金属錯体含有組成物を手のひらに注出した。反対の手の指先を用いて、製品全量をデコルタージュに塗布し、製品を首までたっぷりとフェザーリングして終えた。
3)治療システム製品を塗布した後に手を洗い、眼や口に触れないように注意した。
朝と夕の塗布間隔は少なくとも8時間置いた。
Claims (16)
- シワやシミを治療するデコルタージュ治療用キットあって、デコルタージュ領域に塗布する第1の治療と;
第1の治療適用後、所定の時間後にデコルタージュ領域に塗布する第2の治療を含み、
前記第1の治療はトレチノイン、ヒドロキノン、及び二金属錯体を局所的に塗布することを含み、且つ
前記第2の治療はヒドロキノン及び二金属錯体を局所的に塗布することを含む、ここで前記第1の治療及び前記第2の治療において使用される二金属錯体はマロン酸の中央ユニットを含み、ここでマロン酸の中央ユニットは配位結合によって銅成分及び亜鉛成分と架橋することを特徴とするデコルタージュ治療用キット。 - 請求項1に記載のデコルタージュ治療用キットであって、第1の治療と第2の治療との間の前記所定の時間は、少なくとも4時間であることを特徴とするデコルタージュ治療用キット。
- 第1の治療を朝に行う請求項1に記載のデコルタージュ治療用キット。
- 第2の治療を夕に行う請求項3に記載のデコルタージュ治療用キット。
- 第1の治療を夕に行う請求項1に記載のデコルタージュ治療用キット。
- 前記第1の治療には前記トレチノイン、その後前記ヒドロキノン、さらに前記二金属錯体の順次塗布が含まれることを特徴とする請求項1に記載のデコルタージュ治療用キット。
- 請求項1に記載のデコルタージュ治療用キットであって、前記第1の治療の前記トレチノインおよび前記ヒドロキノンは、デコルタージュ領域へ塗布する前にプレミックスすることを特徴とするデコルタージュ治療用キット。
- 前記ヒドロキノンが1重量%〜5重量%の量で存在する、請求項1に記載のデコルタージュ治療用キット。
- 前記トレチノインが0.025重量%〜0.05重量%の量で存在する、請求項1に記載のデコルタージュ治療用キット。
- 前記ヒドロキノンがアルブチンである請求項1に記載のデコルタージュ治療用キット。
- シワやシミを治療するデコルタージュ治療用キットであって、デコルタージュの領域に塗布するトレチノイン及びヒドロキノンを含む第1の組成物を含み;且つ
少なくとも1つの二金属錯体を含む第2の組成物を含み、前記第2の組成物は第1の組成物を用いて事前に治療された前記デコルタージュの領域に適用し、
前記二金属錯体はマロン酸の中央ユニットを含み、
前記マロン酸の中央ユニットは、配位結合によって銅成分及び亜鉛成分と架橋するものであることを特徴とするキット。 - 前記トレチノイン及び前記ヒドロキノンが前記デコルタージュの領域に順次塗布される、請求項11に記載のキット。
- 前記トレチノイン及びヒドロキノンが前記デコルタージュの領域に同時に塗布される請求項11に記載のキット。
- 前記ヒドロキノンが1重量%〜5重量%の量で存在する、請求項11に記載のキット。
- 前記トレチノインが0.025重量%〜0.05重量%の量で存在する請求項11に記載のキット。
- ヒドロキノンとはアルブチンである請求項11に記載のキット。
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US1904708P | 2008-01-04 | 2008-01-04 | |
US61/019,047 | 2008-01-04 | ||
US12/331,781 US8273791B2 (en) | 2008-01-04 | 2008-12-10 | Compositions, kits and regimens for the treatment of skin, especially décolletage |
US12/331,781 | 2008-12-10 |
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US (2) | US8273791B2 (ja) |
EP (1) | EP2087880A3 (ja) |
JP (1) | JP6043043B2 (ja) |
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Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20160184354A1 (en) * | 2009-01-23 | 2016-06-30 | Jr Chem, Llc | Rosacea treatments and kits for performing them |
US20110008271A1 (en) | 2009-07-13 | 2011-01-13 | Jr Chem, Llc | Rosacea treatments using polymetal complexes |
KR101213219B1 (ko) | 2009-12-17 | 2012-12-17 | 주식회사 제노포커스 | 하이드로퀴논 유도체 및 이의 제조방법 |
US8952057B2 (en) | 2011-01-11 | 2015-02-10 | Jr Chem, Llc | Compositions for anorectal use and methods for treating anorectal disorders |
US10674747B2 (en) | 2012-12-14 | 2020-06-09 | Hill's Pet Nutrition, Inc. | Anti-aging foods for companion animals |
US9474282B2 (en) | 2013-12-13 | 2016-10-25 | Tony John Hall | Acid-solubilized copper-ammonium complexes and copper-zinc-ammonium complexes, compositions, preparations, methods, and uses |
US20150282592A1 (en) * | 2014-04-04 | 2015-10-08 | Jessica A. McCallum | Dispensing system and method |
US10076479B1 (en) | 2018-05-08 | 2018-09-18 | Avon Products, Inc. | Methods for treating skin |
CN107405281A (zh) * | 2015-03-05 | 2017-11-28 | 雅芳产品公司 | 用于处理皮肤的方法 |
FR3035788B1 (fr) * | 2015-05-04 | 2019-11-22 | Total Marketing Services | Nano-emulsion cosmetique |
MX2017015797A (es) | 2015-06-08 | 2018-11-09 | Myco Sciences Ltd | Composiciones antimicrobianas y agroquimicas. |
KR101880447B1 (ko) * | 2015-12-01 | 2018-07-23 | 김배용 | 생리활성물질 복합체, 이의 제조방법 및 이를 포함한 화장료 조성물 |
Family Cites Families (449)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US992937A (en) * | 1911-05-23 | Brodbeck Company | Nursery-powder compound. | |
US284335A (en) * | 1883-09-04 | Eye-water | ||
US173607A (en) * | 1876-02-15 | Improvement in deodorizing, disinfecting, and antiseptic powders | ||
US229014A (en) * | 1880-06-22 | Salve | ||
US92065A (en) | 1869-06-29 | Improved compound to be used in the cure op rheumatism | ||
US140768A (en) * | 1873-07-15 | Improvement in eye-washes | ||
US128385A (en) * | 1872-06-25 | Improvement in medical compounds | ||
US55889A (en) * | 1866-06-26 | Improved eye-water | ||
US46494A (en) * | 1865-02-21 | Improved eye-water | ||
US238015A (en) * | 1881-02-22 | Ointment | ||
US264783A (en) * | 1882-09-19 | Eye-wash | ||
US149857A (en) * | 1874-04-21 | Improvement in medical compounds or liniments | ||
US232807A (en) * | 1880-10-05 | Herbert e | ||
US2870151A (en) | 1959-01-20 | Mqrpholine -ethers | ||
US415208A (en) * | 1889-11-19 | Ointment | ||
US81008A (en) * | 1868-08-11 | Improved eye-wateb | ||
US145749A (en) * | 1873-12-23 | Improvement in medical compounds or eye-washes | ||
US432611A (en) * | 1890-07-22 | Salve | ||
US88973A (en) * | 1869-04-13 | Improved salve for cure of foot-rot in sheep | ||
US62065A (en) * | 1867-02-12 | phillippi | ||
US87343A (en) * | 1869-03-02 | Improved medical compound | ||
US411657A (en) * | 1889-09-24 | Lotion | ||
US116875A (en) * | 1871-07-11 | Improvement in medical compounds | ||
US277221A (en) * | 1883-05-08 | Cosmetic wash | ||
US51868A (en) * | 1866-01-02 | Improved remedy for sore eyes | ||
US430048A (en) * | 1890-06-10 | Medical bandage | ||
US124751A (en) * | 1872-03-19 | Improvement in medical compounds or salves | ||
US143133A (en) * | 1873-09-23 | Improvement in medical compounds or powders for infants | ||
US127925A (en) * | 1872-06-11 | Improvement in medical compounds for treating ringworm | ||
US320836A (en) * | 1885-06-23 | Ointment | ||
US254636A (en) * | 1882-03-07 | Lamp-shade holder | ||
US171875A (en) * | 1876-01-04 | Improvement in cattle-washes | ||
US318468A (en) * | 1885-05-19 | Eye remedy | ||
US3184376A (en) | 1965-05-18 | Method of producing antiseptic composition | ||
US93300A (en) * | 1869-08-03 | Improved eye-sirup | ||
US81711A (en) * | 1868-09-01 | Improved m medical compound for treating horses, cattle | ||
US209331A (en) * | 1878-10-29 | Improvement in medical compounds | ||
US627296A (en) * | 1899-06-20 | Arthur camnitzer | ||
US928539A (en) * | 1908-04-16 | 1909-07-20 | Gennaro Pucciarelli | Lotion. |
US944738A (en) * | 1909-08-16 | 1909-12-28 | Windeler Loose | Medicament for diseases of the mucous membrane. |
US1059841A (en) * | 1912-09-23 | 1913-04-22 | Henry Crookes | Production of colloidal metals. |
US1086900A (en) * | 1913-02-28 | 1914-02-10 | Kalil David | Remedy for syphilis. |
US1332190A (en) * | 1918-06-21 | 1920-02-24 | Meda Mfg Company | Cosmetic |
US1627963A (en) * | 1920-01-30 | 1927-05-10 | Henry C Fuller | Medicinal product |
US1488897A (en) * | 1921-02-07 | 1924-04-01 | Rodney J Wood | Filing system |
US1411577A (en) * | 1921-02-23 | 1922-04-04 | Ervin L Mullins | Ointment |
US1488097A (en) | 1922-03-09 | 1924-03-25 | Henry N Creger | Dentifrice |
US1593485A (en) * | 1925-06-29 | 1926-07-20 | Crosnier Georges Eugene Edme | Antiseptic product |
US1584173A (en) * | 1925-12-05 | 1926-05-11 | Albert C Holzapfel | Antiseptic |
US1809082A (en) * | 1927-05-04 | 1931-06-09 | Epstein & Harris | Product for treating the skin |
US2002829A (en) * | 1929-05-28 | 1935-05-28 | Chemical Foundation Inc | Medicinal preparation |
US1908176A (en) * | 1929-05-28 | 1933-05-09 | Chemical Foundation Inc | Process of making a purified coal tar ointment |
US1949797A (en) * | 1929-07-30 | 1934-03-06 | Kaufmann Hans | Process of producing compositions of matter containing sulphur in colloidal distribution |
US1947568A (en) * | 1930-09-27 | 1934-02-20 | Drug Products Co Inc | Carron oil compound chlorinated cream |
US2153653A (en) * | 1932-01-05 | 1939-04-11 | Stux Gustav | Irradiated dusting powder |
US1982148A (en) * | 1932-08-22 | 1934-11-27 | Jr Angel Zimbron | Medicament for external use and method of producing the same |
US2054989A (en) * | 1933-12-30 | 1936-09-22 | Us Ind Alcohol Co | Compositions for application to the human skin |
US2087162A (en) * | 1935-11-25 | 1937-07-13 | Us Ind Alcohol Co | Perspiration-inhibiting composition |
US2095092A (en) * | 1936-02-21 | 1937-10-05 | Clorox Chemical Co | Ointment |
US2129836A (en) | 1936-07-02 | 1938-09-13 | Cosmetic Res Inc | Cosmetic cream rase |
US2194218A (en) * | 1936-09-21 | 1940-03-19 | Dickeson Thurstan Wyatt | Stable emulsions of water with liquid or liquefiable substances which are immiscible with water |
US2114490A (en) * | 1937-09-27 | 1938-04-19 | Benjamin R Harris | Emulsion |
US2267739A (en) * | 1938-04-05 | 1941-12-30 | George B White | Composition of matter for treating skin diseases |
US2289125A (en) * | 1938-04-18 | 1942-07-07 | Wilfred B Kell | Therapeutic agent for the treatment of fungus infection |
US2254636A (en) | 1938-05-11 | 1941-09-02 | Verl D Vangunten | Medicinal product |
US2223142A (en) * | 1938-07-11 | 1940-11-26 | C B Dolge Company | Fungicidal preparation |
US2241331A (en) * | 1939-01-27 | 1941-05-06 | Wm S Merrell Co | Suppository |
US2299604A (en) * | 1939-12-01 | 1942-10-20 | C B Doige Company | Fungicidal composition |
US2344830A (en) * | 1940-08-15 | 1944-03-21 | Wisconsin Alumni Res Found | Composition of matter for the chemical fixation of diseased tissue preparatory for surgical removal |
US2372807A (en) * | 1941-07-05 | 1945-04-03 | Atlas Powder Co | Absorption bases |
US2370561A (en) * | 1941-07-11 | 1945-02-27 | Schuylkill Chemical Co | Therapeutic product and method of making same |
US2377188A (en) * | 1941-08-07 | 1945-05-29 | Schering Corp | Stabilized filter preparations |
US2376884A (en) * | 1941-08-07 | 1945-05-29 | Schering Corp | Hydroquinone composition |
US2361161A (en) * | 1943-09-21 | 1944-10-24 | Anderson David Charles | Basic filling for tooth cavities |
US2420389A (en) * | 1944-05-18 | 1947-05-13 | Bernard V Travis | Insect repellent composition |
US2420271A (en) * | 1944-05-18 | 1947-05-06 | Bernard V Travis | Insect repellent composition |
US2527686A (en) | 1945-12-26 | 1950-10-31 | Max H Sandberg | Mouthwash |
US2469228A (en) * | 1946-02-18 | 1949-05-03 | Samuel I Gertler | Insect repellent |
US2527685A (en) * | 1946-09-06 | 1950-10-31 | John H Roush | Package wrapper |
US2673364A (en) * | 1948-05-04 | 1954-03-30 | Twix Inc | Dental cleaning pad |
US2556567A (en) * | 1949-04-01 | 1951-06-12 | Tampax Inc | Douche composition |
US2649398A (en) * | 1949-04-01 | 1953-08-18 | Tampax Inc | Douche composition |
US2652355A (en) * | 1950-01-31 | 1953-09-15 | Warner Hudnut Inc | Fungicides |
US2703777A (en) | 1950-05-02 | 1955-03-08 | Iso Sol Company Inc | Ophthalmological preparations and vehicles and method of making the same |
US2602039A (en) * | 1950-05-24 | 1952-07-01 | Dome Chemicals Inc | Crude coal tar dermatological compositions |
US2846322A (en) | 1952-04-29 | 1958-08-05 | Edgar Schaefer | Bactericidal dental cements |
US2748781A (en) | 1953-08-24 | 1956-06-05 | Collat Edgar | Means for dental hygiene |
US2838440A (en) | 1953-10-29 | 1958-06-10 | Rohm & Haas | Dusting powder of carboxylic cationexchange resin and powder base |
US2843522A (en) | 1953-11-17 | 1958-07-15 | Sterling Drug Inc | Peri-anal ointment |
US2870150A (en) | 1954-11-29 | 1959-01-20 | Abbott Lab | Morpholine ethers |
US2736681A (en) | 1955-02-11 | 1956-02-28 | Merck & Co Inc | Chemical compounds |
BE558210A (ja) | 1956-06-08 | |||
US3137622A (en) | 1957-12-23 | 1964-06-16 | Kline | Topical therapeutic composition |
US3035988A (en) | 1958-03-19 | 1962-05-22 | Dover Chemical Corp | Method of forming friction film on hand |
US2991224A (en) | 1958-08-18 | 1961-07-04 | Dale V Bell | Gingival pack |
NL99185C (ja) | 1959-07-30 | |||
US3084105A (en) | 1959-12-18 | 1963-04-02 | Morey E Slodki | Dispersants comprising phosphoric acid monoesters of mannose polymers |
US3013883A (en) | 1960-10-17 | 1961-12-19 | Clyde J Welcker | Process for chemically opening bivalves |
US3164523A (en) | 1961-03-22 | 1965-01-05 | Warner Lambert Pharmaceutical | Composition for skin beautification and treatment |
US3033755A (en) | 1961-04-14 | 1962-05-08 | Kolmar Laboratories | Process for removing the water soluble materials from a keratin structure and cosmetic or pharmaceutical product formed therefrom |
US3146168A (en) | 1962-04-10 | 1964-08-25 | Fmc Corp | Manufacture of pharmaceutical preparations containing cellulose crystallite aggregates |
US3210248A (en) | 1963-09-04 | 1965-10-05 | Merck & Co Inc | Emollient gel comprising lanolin alcohol, microcrystalline wax and a liqquid fatty acid ester |
US3255079A (en) | 1963-06-17 | 1966-06-07 | American Cyanamid Co | Therapeutic dental cement and a method for treating carious teeth |
US3215599A (en) | 1963-07-02 | 1965-11-02 | Warner Lambert Pharmaceutical | Process for preparing polymer waxmodified petroleum oil unctuous base |
US3366114A (en) | 1964-06-29 | 1968-01-30 | Saul L. Kanter | Ileostomy appliance |
US3317372A (en) | 1965-09-29 | 1967-05-02 | Una L Hart | Household deodorant |
US3590123A (en) | 1967-03-09 | 1971-06-29 | Rewo Chem Fab Gmbh | Human hair,skin and nail treatment with sulfosuccinate compositions |
US3903268A (en) | 1968-02-12 | 1975-09-02 | Lescarden Ltd | Chitin and chitin derivatives for promoting wound healing |
US3826845A (en) | 1969-02-08 | 1974-07-30 | Sankyo Co | Ointment base |
US3821371A (en) | 1970-02-02 | 1974-06-28 | Avicon Inc | Pharmaceutical compositions containing microcrystalline collagen,a water-insoluble,ionizable,partial salt of collagen |
US3856934A (en) | 1970-06-24 | 1974-12-24 | A Kligman | Skin depigmentation |
US3749772A (en) | 1970-12-04 | 1973-07-31 | Univ Akron | Dermal protective film |
US3821370A (en) | 1971-03-11 | 1974-06-28 | L Tenta | Topical composition for treating seborrheic keratosis |
US3949072A (en) | 1971-03-11 | 1976-04-06 | Tenta Louis T | Topical composition for treatment of seborrheic keratosis |
US3755560A (en) | 1971-06-30 | 1973-08-28 | Dow Chemical Co | Nongreasy cosmetic lotions |
US4298601A (en) | 1972-03-06 | 1981-11-03 | Technutra, S.A. | Method and formulations for the treatment of obesity |
US3896238A (en) | 1972-04-05 | 1975-07-22 | Procter & Gamble | Dermatological compositions |
US3856941A (en) | 1972-05-23 | 1974-12-24 | Sobel J | Astringent gel, its preparation and use |
US4048300A (en) | 1973-01-11 | 1977-09-13 | Colgate-Palmolive Company | Dental preparation containing materials having calcium and phosphate components |
US4100269A (en) | 1973-06-28 | 1978-07-11 | Lever Brothers Company | Anticalculus dentifrice |
US4309989A (en) | 1976-02-09 | 1982-01-12 | The Curators Of The University Of Missouri | Topical application of medication by ultrasound with coupling agent |
US4138477A (en) | 1976-05-28 | 1979-02-06 | Colgate Palmolive Company | Composition to control mouth odor |
US4166108A (en) | 1977-01-31 | 1979-08-28 | Robert Brown | Styptic composition |
US4136166A (en) | 1977-04-18 | 1979-01-23 | Helena Rubinstein, Inc. | Skin lightening composition |
LU77562A1 (de) | 1977-06-17 | 1979-03-26 | Ciba Geigy Ag | Verfahren zur herstellung von neuen pharmazeutischen praeparaten |
US4331653A (en) | 1977-08-18 | 1982-05-25 | Robert Brown | Composition for a topical cream for curtailing bleeding and treating skin disorders |
US4146607A (en) | 1977-11-07 | 1979-03-27 | Lever Brothers Company | Synergistic anti-plaque mixture with tetradecylamine plus aluminum and/or zinc |
US4273763A (en) | 1978-01-23 | 1981-06-16 | Efamol Limited | Pharmaceutical and dietary compositions |
US4444755A (en) | 1978-01-23 | 1984-04-24 | Efamol Limited | Treatment for skin disorders |
US4160821A (en) | 1978-02-27 | 1979-07-10 | Johnson & Johnson | Treatment for gingivitis |
US4154911A (en) | 1978-06-12 | 1979-05-15 | Mooney Chemicals, Inc. | Elastomers with improved metal adhesion |
US4229427A (en) | 1978-06-28 | 1980-10-21 | The Procter & Gamble Company | Radioactive scanning agents with hydroquinone stabilizer |
US4285967A (en) | 1978-06-30 | 1981-08-25 | Estee Lauder Inc. | Cosmetic preparation for reducing redness of blemishes |
US4315916A (en) | 1978-07-18 | 1982-02-16 | Lucille L. Filson | Topical salve |
US4229437A (en) | 1978-07-18 | 1980-10-21 | Lucille Likens Filson | Paste or dough-like salve for treating skin |
US4161526A (en) | 1978-07-20 | 1979-07-17 | Sterling Drug Inc. | Zinc salt prevention or removal of discoloration in pyrithione, pyrithione salt and dipyrithione compositions |
US4229430A (en) | 1978-08-21 | 1980-10-21 | Fahim Mostafa S | Oral composition for improving oral health |
US4226889A (en) | 1978-12-19 | 1980-10-07 | Dragoco, Inc. | Cosmetic stick composition |
US4322400A (en) | 1978-12-19 | 1982-03-30 | Dragoco Inc. | Cosmetic stick composition |
JPS55106543A (en) | 1979-02-10 | 1980-08-15 | Mitsubishi Gas Chem Co Inc | Preparation of catalyst for synthesizing methanol |
US4255418A (en) | 1979-05-14 | 1981-03-10 | Bailey Florence H | Anti-acne lotion |
US4226851A (en) | 1979-07-11 | 1980-10-07 | Sompayrac Hewitt A | Stable dental composition containing hydrogen peroxide |
US4335110A (en) | 1979-08-23 | 1982-06-15 | Orewa Inc. | Pharmaceutical compositions of sanguinaria galangal and zinc chloride |
US4330527A (en) | 1979-11-13 | 1982-05-18 | Teruo Arima | Wound treatment agent |
US4512978A (en) | 1980-01-24 | 1985-04-23 | Inwood Louis R | Dermatological composition useful in the treatment of psoriasis |
US4310516A (en) | 1980-02-01 | 1982-01-12 | Block Drug Company Inc. | Cosmetic and pharmaceutical vehicle thickened with solid emulsifier |
US4349536A (en) | 1980-03-11 | 1982-09-14 | Hausler Kenneth J | Method of promoting suntan using a cream containing zinc and copper salts |
JPS56139423A (en) | 1980-04-02 | 1981-10-30 | Toyo Seiyaku Kasei Kk | Hemostatic agent for dental oral use |
US4291025A (en) | 1980-04-11 | 1981-09-22 | Laclede Professional Products, Inc. | Agar gel topical dressing |
DE3018969A1 (de) | 1980-05-17 | 1981-11-26 | Beiersdorf Ag, 2000 Hamburg | Mischung fuer halbstarre medizinische stuetzverbaende, damit erhaltene medizinische binde und verfahren zu deren herstellung |
US4406881A (en) | 1980-05-20 | 1983-09-27 | Vipont Laboratories | Antimicrobial agent |
GB2080682B (en) | 1980-07-30 | 1984-03-28 | Ciba Geigy Ag | Antiherpetically active lipstick |
US4376115A (en) | 1980-08-05 | 1983-03-08 | Mccrorey Howard S | Method and composition for treating teeth and method for preparing same |
GB2084870B (en) | 1980-10-10 | 1985-05-09 | Muhlemann R Hans | Oral compositions containing pyrimidine amine compounds and zinc salts |
US4372296A (en) | 1980-11-26 | 1983-02-08 | Fahim Mostafa S | Treatment of acne and skin disorders and compositions therefor |
JPS57145803A (en) | 1981-03-05 | 1982-09-09 | Sunstar Inc | External decoloring agent for skin |
HU195618B (en) | 1981-03-17 | 1988-06-28 | Human Oltoanyagtermelo | Process for producing composition for treating epidermic lesions of skin |
US4477439A (en) | 1981-04-13 | 1984-10-16 | Walter J. Monacelli | Treatment of irritated and excoriated areas around the stoma of ostomy patients |
US4375968A (en) | 1981-07-10 | 1983-03-08 | Manhart Mark J | Therapeutic calcium hydroxide dental preparation and method |
US4421769A (en) | 1981-09-29 | 1983-12-20 | The Procter & Gamble Company | Skin conditioning composition |
US4515779A (en) | 1981-10-23 | 1985-05-07 | Arkansas Medical Research & Development Corporation | Skin tumor removal and healing compositions and processes |
US4430324A (en) | 1981-11-27 | 1984-02-07 | Lever Brothers Company | Ammonium fluorometallate containing compositions |
US4466955A (en) | 1982-06-09 | 1984-08-21 | Germaine Monteil Cosmetiques Corporation | Skin bleaching stick containing hydroquinone |
US4428933A (en) | 1982-08-02 | 1984-01-31 | King John R | Composition for treating acne, method of manufacturing said composition, and method of treating skin |
US4678664A (en) | 1982-09-30 | 1987-07-07 | Basf Corporation | Mineral oil gels |
ZA837627B (en) | 1982-10-15 | 1984-06-27 | Procter & Gamble | Storage stable topical pharmaceutical composition containing low dielectric solvents |
DE3307382C2 (de) | 1983-03-02 | 1990-01-25 | Hans-Peter 8022 Grünwald Walter | Arzneimittel, geeignet zur Behandlung von entzündlichen Veränderungen der Bronchialschleimhaut |
JPS6028999A (ja) | 1983-06-30 | 1985-02-14 | Maruho Kk | 細胞増殖促進作用を有するたんぱく質、その組成物と製造方法 |
JPH0832621B2 (ja) | 1985-02-28 | 1996-03-29 | 株式会社資生堂 | 皮膚外用剤 |
JPS6056912A (ja) * | 1983-09-07 | 1985-04-02 | Shiseido Co Ltd | 皮膚外用剤 |
NZ210840A (en) | 1984-01-18 | 1987-05-29 | Johnson & Johnson Baby Prod | Composition comprising synergistic combination of miconazole nitrate and zinc oxide |
US4568540A (en) | 1984-04-18 | 1986-02-04 | Johnson & Johnson | Oral hygiene compositions |
US4661354A (en) | 1984-06-21 | 1987-04-28 | Finnerty Edmund F | Topical treatment of herpes simplex with a zinc sulfate-camphor water solution |
US4652444A (en) | 1984-12-14 | 1987-03-24 | National Research Laboratories | Methods and compositions for treating dental structures |
US4708864A (en) | 1984-12-14 | 1987-11-24 | National Research Laboratories | Method and compositions for treating dental structures |
JPS61159943A (ja) | 1984-12-29 | 1986-07-19 | 株式会社資生堂 | 皮膚外用剤 |
US4937230A (en) | 1985-01-24 | 1990-06-26 | Procyte Corporation | Method of healing wounds in horses |
US4760051A (en) | 1985-01-24 | 1988-07-26 | Pickart Loren R | Use of GHL-Cu as a wound-healing and anti-inflammatory agent |
US5120831A (en) | 1985-02-08 | 1992-06-09 | Procyte Corporation | Metal-peptide compositions |
US5348943A (en) | 1985-02-08 | 1994-09-20 | Procyte Corporation | Cosmetic and skin treatment compositions |
US4810693A (en) | 1985-02-08 | 1989-03-07 | Procyte Corporation | Method for inducing biological coverings in wounds |
US5214032A (en) | 1985-02-08 | 1993-05-25 | Procyte Corporation | GHL-CU pharmaceutical compositions and compounds |
US5550183A (en) | 1985-02-08 | 1996-08-27 | Procyte Corporation | Metal-peptide compositions and methods for stimulating hair growth |
US5177061A (en) | 1985-02-08 | 1993-01-05 | Procyte Corporation | Method for stimulating hair growth using GHL-Cu complexes |
US4767753A (en) | 1985-02-08 | 1988-08-30 | Procyte Corporation | Methods and compositions for preventing ulcers |
US4877770A (en) | 1985-02-08 | 1989-10-31 | Procyte Corporation | Chemical derivatives of GHL-Cu |
US4665054A (en) | 1985-02-08 | 1987-05-12 | Bioheal, Inc. | Chemical derivatives of GHL-Cu |
US4895727A (en) | 1985-05-03 | 1990-01-23 | Chemex Pharmaceuticals, Inc. | Pharmaceutical vehicles for exhancing penetration and retention in the skin |
US5154932A (en) | 1985-07-05 | 1992-10-13 | The Dow Chemical Company | Antimicrobial positively charged particles |
US4683133A (en) | 1985-08-20 | 1987-07-28 | Vipont Laboratories, Inc. | Method for treating periodontal disease |
US4654213A (en) | 1985-09-11 | 1987-03-31 | Cheesebrough-Pond's Inc. | Novel anti-microbial systems containing the magnesium sulfate adduct of 2,2'-dithiobis-pyridine-1,1'-dioxide and a water soluble zinc salt |
US4713242A (en) | 1985-11-07 | 1987-12-15 | Tecma Laboratories, Inc. | Skin therapeutic mixture containing eupatorium extract |
US4647452A (en) | 1985-11-08 | 1987-03-03 | Lever Brothers Company | Oral compositions of salicylamides and zinc salts for the synergistic inhibition of dental plaque |
US4792443A (en) | 1985-12-20 | 1988-12-20 | Warner-Lambert Company | Skin bleaching preparations |
US4847083A (en) | 1986-04-02 | 1989-07-11 | Dermasciences, Inc. | Two-step procedure for indolent wound healing and aqueous medium and topical ointment used in connection therewith |
US4863987A (en) | 1986-04-07 | 1989-09-05 | Dainichiseika Color & Chemicals Mfg. Co., Ltd. | Deodorizing coating formulations and deodorizing sheets making use of same |
US4855138A (en) | 1986-06-24 | 1989-08-08 | Tecma Laboratories, Inc. | Skin therapeutic mixture containing matico extract |
US5389677B1 (en) | 1986-12-23 | 1997-07-15 | Tristrata Inc | Method of treating wrinkles using glycalic acid |
US5091171B2 (en) | 1986-12-23 | 1997-07-15 | Tristrata Inc | Amphoteric compositions and polymeric forms of alpha hydroxyacids and their therapeutic use |
US5385938B1 (en) | 1986-12-23 | 1997-07-15 | Tristrata Inc | Method of using glycolic acid for treating wrinkles |
US4874361A (en) | 1986-12-29 | 1989-10-17 | Obagi Zein E | Method for healing damaged skin |
US5166176A (en) | 1986-12-29 | 1992-11-24 | Obagi Zein E | Composition for healing damaged skin |
EP0314755B1 (en) | 1987-05-11 | 1994-08-24 | Procyte Corporation | Use of derivatives of GHL-Cu for the manufacture of a medicament for stimulating hair growth |
US4816254A (en) | 1987-07-29 | 1989-03-28 | Moss Thomas D | Ointment for treating skin irritations |
US5093099A (en) | 1987-11-16 | 1992-03-03 | Kao Corporation | Flaky powder of zinc oxide and its composition for external use |
US4849211A (en) | 1988-03-16 | 1989-07-18 | Schrauzer Gerhard N | Product and method for the treatment of acne and other skin disorders |
DE3929411A1 (de) | 1988-09-22 | 1990-03-29 | Siegfried Natterer | Pharmazeutische zubereitung sowie verfahren zu ihrer herstellung |
US4938969A (en) | 1988-11-14 | 1990-07-03 | Milor Scientific, Ltd. | Method for the treatment of aging or photo-damaged skin |
US4956354A (en) | 1988-12-06 | 1990-09-11 | Thomas G. Kottke | Therapeutic preparation for use on skin |
GB8902300D0 (en) | 1989-02-02 | 1989-03-22 | Bryce Smith Derek | Antirhinoviral preparations |
US5232691A (en) | 1989-04-26 | 1993-08-03 | Lemole Gerald M | Protective gel composition |
US5209932A (en) | 1989-05-30 | 1993-05-11 | Moleculon, Inc. | Foot care compositions |
US5624675A (en) | 1989-06-06 | 1997-04-29 | Kelly; Patrick D. | Genital lubricants containing zinc salts to reduce risk of HIV infection |
US5000944A (en) | 1989-06-09 | 1991-03-19 | Colgate-Palmolive Company | Zinc-containing oral products with reduced astringency |
IL91047A (en) | 1989-07-19 | 1993-06-10 | Yissum Res Dev Co | Zinc complexes for the treatment of free radical- induced diseases |
FR2651125B1 (fr) | 1989-08-23 | 1992-10-02 | Roussel Uclaf | Compositions pharmaceutiques de type "pates a l'eau". |
US5023237A (en) | 1989-08-30 | 1991-06-11 | Procyte Corporation | Methods and compositions for healing ulcers |
US5145838A (en) | 1989-08-30 | 1992-09-08 | Procyte Corporation | Methods and compositions for healing ulcers |
US5554647A (en) | 1989-10-12 | 1996-09-10 | Perricone; Nicholas V. | Method and compositions for treatment and/or prevention of skin damage and aging |
US5059588A (en) | 1989-10-13 | 1991-10-22 | Procyte Corporation, Incorporated | Methods and compositions for healing bone using gly his lys: copper |
US4992259A (en) | 1990-01-03 | 1991-02-12 | Johnson & Johnson Consumer Products, Inc. | Stable oral composition of zinc |
US5310546A (en) | 1990-02-07 | 1994-05-10 | 7-L Corporation | Mouthrinse and method of preparation |
US5104644A (en) | 1990-02-07 | 1992-04-14 | 7-L Corporation | Mouthrinse composition |
US5174990A (en) | 1990-02-07 | 1992-12-29 | 7-L Corporation | Mouthrinse and method of preparation |
US5118665A (en) | 1990-02-09 | 1992-06-02 | Procyte Corporation | Anti-oxidative and anti-inflammatory metal:peptide complexes and uses thereof |
US5164367A (en) | 1990-03-26 | 1992-11-17 | Procyte Corporation | Method of using copper(ii) containing compounds to accelerate wound healing |
US6103273A (en) | 1990-07-03 | 2000-08-15 | Antoun; Jacques | Pharmaceutical composition comprising starch, a compound comprising boron, a compound comprising zinc, and water, and a method of using same to encourage hair growth |
US5401730A (en) | 1990-07-06 | 1995-03-28 | The Hope Heart Institute | Method for reducing platelet aggregation |
JPH0474515A (ja) | 1990-07-13 | 1992-03-09 | Toray Ind Inc | 酸素吸収体 |
US5165914A (en) | 1991-03-04 | 1992-11-24 | David G. Vlock | Oral compositions containing zinc lactate complexes |
FR2675997B1 (fr) | 1991-05-03 | 1993-12-24 | Oreal | Composition topique anti radicaux libres a base de superoxyde-dismutase et d'un derive phosphonique. |
FR2679133B1 (fr) | 1991-07-17 | 1993-10-15 | Oreal | Utilisation de derives d'acides (2,5-dihydroxyphenyl)carboxyliques, leurs homologues et leurs sels dans la preparation d'une composition cosmetique ou dermatologique a action depigmentante. |
US5980477A (en) | 1991-07-29 | 1999-11-09 | Patrick Kelly | Genital lubricants with zinc salts as anti-viral additives |
FR2679775B1 (fr) | 1991-08-01 | 1994-11-18 | Grimbert Georges | Medicament a base de derives soufres neutralises. |
GB9117140D0 (en) | 1991-08-08 | 1991-09-25 | Unilever Plc | Treatment of periodontitis |
US5244651A (en) | 1991-09-04 | 1993-09-14 | Kao Corporation | Method of desensitizing hypersensitive dentin |
US5270031A (en) | 1991-12-20 | 1993-12-14 | Block Drug Company Inc. | Dentinal desensitizing compositions |
US5523077A (en) | 1992-02-06 | 1996-06-04 | Yale University | Composition and method for whitening skin |
DE4205828A1 (de) | 1992-02-26 | 1993-09-02 | Henkel Kgaa | Viruswirksame desinfektionsmittel |
US5696169A (en) | 1992-03-13 | 1997-12-09 | Otsuka Pharmaceutical Co., Ltd. | Antibacterial and antifungal activity method, therapeutic method of infectious diseases and preserving method of cosmetics |
US5227156A (en) | 1992-04-14 | 1993-07-13 | Amway Corporation | Use of zinc compounds to stabilize a thiazolinone preservative in an anti-dandruff shampoo |
US5688492A (en) | 1992-05-22 | 1997-11-18 | The Boots Company Plc, | Oral hygiene composition |
US6221403B1 (en) | 1992-08-08 | 2001-04-24 | Seton Healthcare Group Plc | Topical composition |
DE4231622C2 (de) | 1992-09-22 | 1996-09-05 | Bakelite Ag | Verfahren zur Herstellung von Metallneutralkomplexen mit hoher Koordinationszahl und deren Verwendung |
US5382431A (en) | 1992-09-29 | 1995-01-17 | Skin Biology, Inc. | Tissue protective and regenerative compositions |
FR2697161B1 (fr) | 1992-10-26 | 1995-01-13 | Jouvance Daniel | Produit cosmétique à potentiel redox stabilisé. |
US7014870B1 (en) | 1992-11-06 | 2006-03-21 | Greystone Medical Group, Inc. | Compositions of oak bark extract related synthetic compositions and method of using same |
ATE191850T1 (de) | 1992-11-06 | 2000-05-15 | Greystone Medical Group Inc | Eichenrindenextraktverwandte synthetische zubereitungen und verfahren zur verwendung |
US5468860A (en) | 1992-11-19 | 1995-11-21 | Merck & Co., Inc. | New finasteride processes |
JPH06192062A (ja) | 1992-12-24 | 1994-07-12 | Shiseido Co Ltd | 皮膚外用剤 |
WO1994020068A1 (en) | 1993-03-10 | 1994-09-15 | Yale University | Composition and method for whitening skin |
EP0697861B1 (en) | 1993-05-13 | 1998-08-26 | Unilever N.V. | Oral compositions containing triclosan for the treatment of aphthous ulcers |
US5385727A (en) | 1993-05-19 | 1995-01-31 | Church & Dwight Co., Inc. | Dentifrices containing zinc oxide particles and sodium bicarbonate |
US5330748A (en) | 1993-05-19 | 1994-07-19 | Church & Dwight Co., Inc. | Dentifrices containing zinc oxide particles |
US5302373A (en) | 1993-06-10 | 1994-04-12 | Church & Dwight Co., Inc. | Liquid mouthwash containing a particulate bicarbonate suspension |
US5424077A (en) | 1993-07-13 | 1995-06-13 | Church & Dwight Co., Inc. | Co-micronized bicarbonate salt compositions |
US5496539A (en) | 1993-07-22 | 1996-03-05 | The Procter & Gamble Company | Oral compositions |
US5484597A (en) | 1993-07-30 | 1996-01-16 | Chesebrough-Pond's Usa Co. | Clear hydroalcholic cosmetic microemulsions |
US5480975A (en) | 1994-02-08 | 1996-01-02 | Brigham And Women's Hospital | Induction of vascular endothelial growth factor (VEGF) by transition metals |
US5663213A (en) | 1994-02-28 | 1997-09-02 | Rohm And Haas Company | Method of improving ultraviolet radiation absorption of a composition |
FR2717079B1 (fr) | 1994-03-11 | 1996-04-12 | Oreal | Composition contenant un oxyde de métal non photocatalytique et du tocophérol, son utilisation dans le domaine cosmétique et/ou dermatologique et procédés la mettant en Óoeuvre. |
EP0788305B1 (en) | 1994-03-28 | 2004-11-03 | The Trustees of Columbia University in the City of New York | Composition for inactivating irritants in fluids |
AU2231495A (en) | 1994-03-28 | 1995-10-17 | Skin Biology, Inc. | Starch-metal complexes for skin and hair |
FR2719481B1 (fr) | 1994-05-05 | 1996-05-31 | Oreal | Composition à base de composés antifongiques et de composés antibactériens halogènes pour diminuer la chute des cheveux. |
US5645840A (en) | 1994-05-25 | 1997-07-08 | Church & Dwight Co., Inc. | Ultrafine sodium bicarbonate powder |
WO1995033688A1 (fr) | 1994-06-06 | 1995-12-14 | Nippon Shokubai Co., Ltd. | Fines particules d'oxyde de zinc, procede de production de ces particules et leur utilisation |
US5632972A (en) | 1994-06-30 | 1997-05-27 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Method for treating gingival and periodontal tissues |
US5482720A (en) | 1994-10-11 | 1996-01-09 | Church & Dwight Co., Inc. | Encapsulated co-micronized bicarbonate salt compositions |
US5686083A (en) | 1994-12-08 | 1997-11-11 | Schering-Plough Healthcare Products Inc. | Compositions for treating corns and calluses |
US5597550A (en) | 1994-12-09 | 1997-01-28 | Buxing Mo | Apparatus and method for administering minerals |
FR2728163A1 (fr) | 1994-12-20 | 1996-06-21 | Oreal | Composition cosmetique, dermatologique ou pharmaceutique stable contenant du disulfure de selenium et au moins un sel de zinc |
GB9502253D0 (en) | 1995-02-06 | 1995-03-29 | Giltech Ltd | The effects of antibacterial agents on the behaviour of mouse fibroblasts in vitro |
US5552147A (en) | 1995-04-25 | 1996-09-03 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Petroleum jelly with alpha hydroxy carboxylic acids |
US5951990A (en) | 1995-05-15 | 1999-09-14 | Avon Products, Inc. | Ascorbyl-phosphoryl-cholesterol |
US5747005A (en) | 1995-08-02 | 1998-05-05 | Barels; Ronald R. | Oil-based, anti-plaque dentifrice composition |
US5631013A (en) | 1995-08-07 | 1997-05-20 | Church & Dwight Co., Inc. | Cosmetic deodorant products containing encapsulated co-micronized bicarbonate ingredient |
WO1997009032A1 (fr) | 1995-09-07 | 1997-03-13 | L'oreal | Utilisation d'un extrait d'une bacterie filamenteuse non photosynthetique et composition le contenant |
US6750209B1 (en) | 1995-09-12 | 2004-06-15 | Kansas University Medical Center | Advanced glycation end-product intermediaries and post-amadori inhibition |
US5827884A (en) | 1995-09-15 | 1998-10-27 | Omp Acquisition Corporation | Skin peel maintenance composition and method |
US6083490A (en) | 1995-11-06 | 2000-07-04 | M&J Consultants Pty Ltd | UV absorbing compositions |
FR2747044B1 (fr) | 1996-04-03 | 1998-06-26 | Coletica | Utilisation de graines de vegetaux apres germination comme source de superoxyde dismutase et compositions cosmetiques, pharmaceutiques ou agroalimentaires contenant une telle superoxyde dismutase vegetale, et procede d'extraction |
US5762945A (en) | 1996-04-05 | 1998-06-09 | Ashley; Eline | Composition and method for treating diaper rash |
JP2822317B2 (ja) | 1996-04-15 | 1998-11-11 | 日鉄鉱業株式会社 | 抗菌性チタニア及びその製造方法 |
US5955067A (en) | 1996-07-23 | 1999-09-21 | Oge; Eray | Potassium-containing composition useful in the treatment of acne, psoriasis and seborrhea |
US6040333A (en) | 1996-07-30 | 2000-03-21 | Energetics, Inc. | Dietary supplements |
ES2180794T3 (es) | 1996-08-21 | 2003-02-16 | Childrens Hosp Medical Center | Composiciones para el aclarado de la piel. |
US5888522A (en) | 1996-08-23 | 1999-03-30 | Skin Biology, Inc. | Tissue protective and regenerative compositions |
US5698184A (en) | 1996-08-23 | 1997-12-16 | Skin Biology, Inc. | Compositions and methods for skin tanning and protection |
US5837270A (en) | 1996-08-26 | 1998-11-17 | Burgess; Nelson Leon | Topical anti-acne composition |
US5753637A (en) | 1996-10-09 | 1998-05-19 | Ideal Ideas, Inc. | Method of treating acne conditions |
JP3187440B2 (ja) | 1996-10-23 | 2001-07-11 | カネボウ株式会社 | 活性抑制型酸化亜鉛粉体および化粧料 |
US5911976A (en) | 1996-10-24 | 1999-06-15 | The Procter & Gamble Company | Compositions for reducing body odor |
US5882638A (en) | 1996-10-24 | 1999-03-16 | The Proctor & Gamble Company | Methods using uncomplexed cyclodextrin solutions for controlling environmental odors |
US5897855A (en) | 1996-10-24 | 1999-04-27 | The Procter & Gamble Company | Methods and compositions for reducing body odor |
US5874067A (en) | 1996-10-24 | 1999-02-23 | The Procter & Gamble Company | Methods for controlling environmental odors on the body |
US5879666A (en) | 1996-10-24 | 1999-03-09 | The Procter & Gamble Company | Methods and compositions for reducing body odor |
US5897856A (en) | 1996-10-24 | 1999-04-27 | The Procter & Gamble Company | Methods and compositions for reducing body odor |
US5780020A (en) | 1996-10-28 | 1998-07-14 | The Proctor & Gamble Company | Methods and compositions for reducing body odor |
US6497860B1 (en) | 1996-11-04 | 2002-12-24 | Children's Hospital Medical Center | Skin lightening compositions |
US6471972B1 (en) | 1996-11-07 | 2002-10-29 | Lvmh Recherche | Cosmetic treatment method for fighting against skin ageing effects |
US5804594A (en) | 1997-01-22 | 1998-09-08 | Murad; Howard | Pharmaceutical compositions and methods for improving wrinkles and other skin conditions |
IN186803B (ja) | 1997-02-05 | 2001-11-10 | Panacea Biotec Ltd | |
GB9706318D0 (en) | 1997-03-26 | 1997-05-14 | Bryant Andrew E | Therapeutic formulations |
US6030605A (en) | 1997-04-03 | 2000-02-29 | Nabisco, Inc. | Breath freshening compositions and methods using them |
US6046178A (en) | 1997-04-18 | 2000-04-04 | Deroyal Industries, Inc. | Method and compound for treating wounds with starch hydrolysate medication |
US6372234B1 (en) | 1997-05-27 | 2002-04-16 | Sembiosys Genetics Inc. | Products for topical applications comprising oil bodies |
US6599513B2 (en) | 1997-05-27 | 2003-07-29 | Sembiosys Genetics Inc. | Products for topical applications comprising oil bodies |
US6071543A (en) | 1997-06-02 | 2000-06-06 | Cellegy Pharmaceuticals, Inc. | Pyridine-thiols reverse mucocutaneous aging |
US5861145A (en) | 1997-06-09 | 1999-01-19 | The Procter & Gamble Company | Method of reducing body odor using perfumed, odor absorbing, two phase compositions |
US5861144A (en) | 1997-06-09 | 1999-01-19 | The Procter & Gamble Company | Perfumed compositions for reducing body odors and excess moisture |
US5874070A (en) | 1997-06-09 | 1999-02-23 | The Procter & Gamble Company | Compositions for reducing body odor |
US5871719A (en) | 1997-06-09 | 1999-02-16 | The Procter & Gamble Company | Perfume-free two phase compositions for reducing body odor |
US5858335A (en) | 1997-06-09 | 1999-01-12 | The Procter & Gamble Company | Method of reducing body odor using perfume-free two phase compositions |
US5942214A (en) | 1997-06-09 | 1999-08-24 | The Procter & Gamble Company | Methods for controlling environmental odors on the body using compositions comprising uncomplexed cyclodextrins and perfume |
US5897854A (en) | 1997-06-09 | 1999-04-27 | The Procter & Gamble Company | Methods for reducing body odor |
US5861146A (en) | 1997-06-09 | 1999-01-19 | The Procter & Gamble Company | Method for reducing body odor |
US5861147A (en) | 1997-06-09 | 1999-01-19 | The Procter & Gamble Company | Methods for controlling environmental odors on the body using compositions comprising uncomplexed cyclodextrins and perfume |
US5871718A (en) | 1997-06-09 | 1999-02-16 | The Procter & Gamble Company | Perfumed two phase compositions for reducing body odor |
US5928631A (en) | 1997-06-09 | 1999-07-27 | The Procter & Gamble Company | Methods for controlling environmental odors on the body using compositions comprising uncomplexed cyclodextrins |
US5861143A (en) | 1997-06-09 | 1999-01-19 | The Procter & Gamble Company | Methods for reducing body odors and excess moisture |
US6331567B1 (en) | 1997-06-13 | 2001-12-18 | Mars Uk Limited | Edible composition containing zinc and linoleic acid |
JP3848742B2 (ja) | 1997-07-03 | 2006-11-22 | メルク株式会社 | 紫外線遮蔽用顔料 |
US6248370B1 (en) | 1997-07-24 | 2001-06-19 | Leroy Harris | Skin treatment and methods |
AU8588898A (en) | 1997-07-28 | 1999-02-16 | Mary L. Redmond | Composition and process for the treatment of epidermal traumas such as decubitusulcers |
US5874094A (en) | 1997-08-05 | 1999-02-23 | Costello; Jeremiah | Cream formulation for topical application |
US5948390A (en) | 1997-08-25 | 1999-09-07 | Pfizer Inc. | Stable zinc/citrate/CPC oral rinse formulations |
JP4034430B2 (ja) | 1997-09-10 | 2008-01-16 | 三好化成株式会社 | 有機ケイ素化合物処理粉体基材、その製造方法及び前記基材を含有する化粧料 |
US5855873A (en) | 1997-10-27 | 1999-01-05 | Church Dwight & Co., Inc. | Stable solution of zinc and bicarbonate ions |
US6113636A (en) | 1997-11-20 | 2000-09-05 | St. Jude Medical, Inc. | Medical article with adhered antimicrobial metal |
US6267782B1 (en) | 1997-11-20 | 2001-07-31 | St. Jude Medical, Inc. | Medical article with adhered antimicrobial metal |
US5928658A (en) | 1997-12-05 | 1999-07-27 | U.S. Cosmetics | Oil-free wax-free solid cosmetic composition |
US5888515A (en) | 1997-12-11 | 1999-03-30 | Albros, L.P. | Rhus dermatitis treatment composition and method |
US5994403A (en) | 1997-12-17 | 1999-11-30 | Donatiello; Steven T. | Tannin (tannic acid) treatment of athlete's foot and other fungal infections |
US6191167B1 (en) | 1997-12-29 | 2001-02-20 | Tristrata Technology, Inc. | Pharmaceutical compositions containing hydroxycarboxylic acid and/or ketocarboxylic acids and methods of using the same |
FR2777178B1 (fr) | 1998-04-10 | 2000-06-02 | Oreal | Kit de maquillage associant un pigment goniochromatique et un pigment monocolore ayant une des couleurs du pigment goniochromatique, ses utilisations |
EP0960572A1 (en) | 1998-05-12 | 1999-12-01 | N.V. Nutricia | Nutritional composition for the treatment of pressure ulcers |
US20030190371A1 (en) | 1998-05-21 | 2003-10-09 | The Boots Company Plc | Antimicrobial agent |
US6123925A (en) | 1998-07-27 | 2000-09-26 | Healthshield Technologies L.L.C. | Antibiotic toothpaste |
FR2782642B1 (fr) | 1998-08-31 | 2001-12-07 | Xavier Forceville | Utilisation du selenium pour le traitement de patients atteints d'un syndrome de reponse inflammatoire systemique (sirs), et composition pour la mise en oeuvre du traitement |
US6060079A (en) | 1998-09-09 | 2000-05-09 | Freeman; Frank | Device for topical localized administration of zinc to tissue |
AU1033400A (en) | 1998-09-23 | 2000-04-17 | Joiner, Andrew | Oral composition with an improved teeth whitening effect |
US6607716B1 (en) | 1998-09-29 | 2003-08-19 | Tech Labs, Inc. | Pediculicidal compositions, a kit, and methods of use |
US6183785B1 (en) | 1998-11-12 | 2001-02-06 | Geoffrey J. Westfall | Teat disinfectant |
US5965137A (en) | 1998-11-16 | 1999-10-12 | Advanced Medical Instruments | Insect repellent composition and method for inhibiting the transmission and treatment of symptoms of vector-borne diseases |
FR2787995B1 (fr) | 1998-12-30 | 2002-05-03 | Oreal | Compostion cosmetique hydrophobe anhydre sous forme de poudre compacte |
US6217914B1 (en) | 1999-03-19 | 2001-04-17 | Bioderm, Inc. | Ascorbic acid composition and method for treatment of aging or damaged skin |
EP1162936B1 (en) | 1999-03-23 | 2011-07-13 | Pyramid Productions Inc. | Body coating composition |
US6680073B1 (en) | 1999-04-08 | 2004-01-20 | Bryon J. Tarbet | Composition and method for the treatment of onychomycosis in animals |
CA2272732C (en) | 1999-05-25 | 2008-07-29 | Sylvain Simoneau | Hemorrhoidal treatment composition |
US6558710B1 (en) | 1999-06-14 | 2003-05-06 | Helen Rebecca Godfrey | Topical zinc compositions and methods of use |
US7026308B1 (en) | 1999-06-25 | 2006-04-11 | The Procter & Gamble Company | Topical anti-microbial compositions |
US6627178B1 (en) | 1999-07-30 | 2003-09-30 | Garret D. Cawthon | Methods, compositions and systems for the prevention and treatment of diaper rash |
US7115535B1 (en) | 1999-08-02 | 2006-10-03 | The Procter & Gamble Company | Personal care articles comprising batting |
US6322588B1 (en) | 1999-08-17 | 2001-11-27 | St. Jude Medical, Inc. | Medical devices with metal/polymer composites |
US6375942B1 (en) | 1999-08-31 | 2002-04-23 | Michael C. Rico | Skin healing ointment |
US6479058B1 (en) | 1999-09-02 | 2002-11-12 | Mccadden Michael E. | Composition for the topical treatment of poison ivy and other forms of contact dermatitis |
US6303651B1 (en) | 1999-09-23 | 2001-10-16 | Thione International, Inc. | Synergistic antioxidant veterinary compositions |
US6517849B1 (en) | 1999-10-19 | 2003-02-11 | The Procter & Gamble Company | Tissue products containing antiviral agents which are mild to the skin |
US20010014356A1 (en) | 1999-12-24 | 2001-08-16 | Yuzo Yoshida | Plasminogen activator inhibitor and external preparation for skin comprising the same |
JP4558122B2 (ja) | 2000-01-14 | 2010-10-06 | 株式会社資生堂 | 抗菌防カビ剤及び抗菌防カビ組成物 |
US6521265B1 (en) | 2000-02-09 | 2003-02-18 | Biolife, L.L.C. | Method for applying a blood clotting agent |
US7405080B2 (en) | 2000-03-23 | 2008-07-29 | Voellmy Richard W | Compositions and methods relating to prevention of chemotherapy-induced alopecia |
US6579541B2 (en) | 2000-03-28 | 2003-06-17 | Marantech Holding, Llc | Oxidative fluorinator compounds as antimicrobials |
US6361800B1 (en) | 2000-04-13 | 2002-03-26 | Cooper Concepts, Inc. | Multi-vitamin and mineral supplement |
EP1278504A2 (en) | 2000-05-05 | 2003-01-29 | R.P. Scherer Technologies, Inc. | Oil-in-water emulsion formulation containing hydroquinone and retinol |
AU4871501A (en) | 2000-05-08 | 2001-11-20 | Pfizer Prod Inc | Skin protectant spray compositions |
US20040058015A1 (en) | 2000-06-01 | 2004-03-25 | Yuanjin Tao | Compositions and methods for treating eye discomfort and eye disease |
US6833362B2 (en) | 2000-06-12 | 2004-12-21 | Ward Beryl Bowen, Jr. | Method and composition for the accelerated in vivo removal of ethanol |
EP2036540A3 (en) | 2000-06-16 | 2009-12-16 | Jagotec AG | Improved injectable dispersions of propofol |
JP3822782B2 (ja) | 2000-07-06 | 2006-09-20 | 三好化成株式会社 | 皮脂吸着性粉体及びその使用 |
US20040220100A1 (en) | 2000-07-21 | 2004-11-04 | Essentia Biosystems, Inc. | Multi-component biological transport systems |
US20030215412A1 (en) | 2000-07-21 | 2003-11-20 | Essentia Biosystems, Inc. | Induction of hair growth with vascular endothelial growth factor |
US7008647B2 (en) | 2001-04-23 | 2006-03-07 | Nucryst Pharmaceuticals Corp. | Treatment of acne |
ATE395901T1 (de) | 2000-09-11 | 2008-06-15 | Showa Denko Kk | Kosmetische sonnenschutz-zubereitung |
TWI292322B (en) | 2000-09-25 | 2008-01-11 | Shiseido Co Ltd | Metal oxide/silica complex and cosmetics containing the same |
US6660306B2 (en) | 2000-10-12 | 2003-12-09 | Mickey L. Peshoff | Wound healing compound |
GB0029018D0 (en) | 2000-11-28 | 2001-01-10 | Strakan Group Plc | Dermatological formulations |
DE10063090A1 (de) | 2000-12-18 | 2002-06-20 | Henkel Kgaa | Nanoskaliges ZnO in Hygiene-Produkten |
WO2002064104A1 (en) | 2001-02-15 | 2002-08-22 | Pickart Loren R | Methods for treating fingernails and toenails |
NL1017487C2 (nl) | 2001-03-02 | 2002-09-06 | Caral B V I O | Preparaat met polydimethylsiloxaan voor aandoeningen van nagels, kraakbeen, botten, gewrichten, spieren en pezen. |
US6780439B2 (en) | 2001-03-06 | 2004-08-24 | J. Ronald Wilk | Wound treatment solution and method for using same |
GB2374008B (en) | 2001-04-04 | 2005-03-16 | John Carter | Pharmaceutical compositions comprising copper and zinc |
US6800301B2 (en) | 2001-04-09 | 2004-10-05 | Sadie N. Smith | Multi-purpose skin balm including skin balm for psoriasis |
US7056339B2 (en) | 2001-04-20 | 2006-06-06 | The Board Of Trustees Of The Leland Stanford Junior University | Drug delivery platform |
JP2004529930A (ja) | 2001-04-23 | 2004-09-30 | ニュクリスト ファーマシューティカルズ コーポレーション | 炎症性皮膚状態の治療のための金属の使用 |
WO2002089741A2 (en) | 2001-05-04 | 2002-11-14 | Theralife, Inc. | Compositions and methods for enhancing drug delivery |
FR2824474B1 (fr) | 2001-05-11 | 2004-01-02 | Fabre Pierre Dermo Cosmetique | Composition cosmetique a base de sucralfate et de sulfates de cuivre et de zinc |
US7189759B2 (en) | 2001-05-23 | 2007-03-13 | Medicis Pharmaceutical Corporation | Compositions for the treatment of pigmentation disorders and methods for their manufacture |
US6475526B1 (en) | 2001-06-05 | 2002-11-05 | Jeffrey B. Smith | Zinc containing compositions for anti-viral use |
DK1399128T3 (da) | 2001-06-15 | 2007-01-08 | Innovent Technology Ltd | Sammensætning til behandling af sygdomme, der angriber dyrs hove/klove |
US6416744B1 (en) | 2001-06-21 | 2002-07-09 | Colgate Palmolive Company | Tooth whitening chewing gum |
US20030026848A1 (en) | 2001-07-06 | 2003-02-06 | Joshi Ashok V. | Beneficial materials for topical or internal use by a human or other animal |
TNSN02063A1 (en) | 2001-07-07 | 2005-12-23 | Egyptian Natural Oil Co Natoil | The medical effect of jojoba oil |
US6699464B1 (en) | 2001-07-30 | 2004-03-02 | Stiefel Laboratories, Inc. | Compositions for treatment of hyperpigmentation and methods for making and using such compositions |
US6605291B2 (en) | 2001-08-01 | 2003-08-12 | Parker Holding Services Corp. | Therapeutic pad and a method for treatment of common illnesses |
US6929800B2 (en) | 2001-08-06 | 2005-08-16 | Abdul Rasoul Salman | Nasal passage cleaning composition |
US20040076686A1 (en) | 2001-08-10 | 2004-04-22 | Thomas Riesinger | Treatment solution used for caring wounds in addition to dressing material for use with said treatment solution |
ATE332879T1 (de) | 2001-08-22 | 2006-08-15 | Schott Ag | Antimikrobielles, entzündungshemmendes, wundheilendes glaspulver und dessen verwendung |
US6699509B1 (en) | 2001-09-17 | 2004-03-02 | Silvia Melinte | Tattoo removal |
US20030082219A1 (en) | 2001-10-01 | 2003-05-01 | The Procter & Gamble Company | Skin care compositions comprising low concentrations of skin treatment agents |
US6849277B2 (en) | 2001-10-09 | 2005-02-01 | Juan Carlos Roig | Composition for moist skin |
US20050238730A1 (en) | 2001-11-21 | 2005-10-27 | Agnes Le Fur | Compositions comprising an ethanolamine derivative and organic metal salts |
US6696071B2 (en) | 2001-11-27 | 2004-02-24 | Patrick D. Kelly | Pre-coital and post-coital rinse with anti-viral and skin-protective zinc salts |
CA2468390A1 (en) | 2001-11-29 | 2003-06-05 | Greystone Medical Group, Inc. | Treatment of wounds and compositions employed |
US20040170703A1 (en) | 2001-11-29 | 2004-09-02 | Greystone Medical Group, Inc. | Reduction of reactive oxygen species in chronic wound management |
ITBS20010111A1 (it) | 2001-12-20 | 2003-06-20 | Paoli Ambrosi Gianfranco De | Composizione per uso topico a base dell'estere etilico dell'acido linoleico e e del trietil estere dell'acido citrico associati con opportun |
DE10163256A1 (de) | 2001-12-21 | 2003-07-10 | Henkel Kgaa | Oberflächenmodifiziertes Zinkoxid zur Herstellung nanopartikulärer Dispersionen |
FR2834445B1 (fr) * | 2002-01-09 | 2004-04-02 | Sofradim Production | Anneau gastrique de traitement de l'obesite |
US20030161892A1 (en) | 2002-02-27 | 2003-08-28 | Mcfarland Connie L. | Topical clotting ointment and method |
DE10212680A1 (de) | 2002-03-22 | 2003-10-09 | Degussa | Nanoskaliges Zinkoxid, Verfahren zu seiner Herstellung und Verwendung |
US20030194446A1 (en) | 2002-04-10 | 2003-10-16 | Akes Lindy K. | Zinc oxide compositions for dermatheraputics |
CA2481994C (en) | 2002-04-22 | 2009-12-08 | The Procter & Gamble Company | Personal care compositions comprising a zinc containing material in an aqueous surfactant composition |
US20030199488A1 (en) | 2002-04-23 | 2003-10-23 | Trotta Gina M. | Treatment of hyperproliferative disorders/inflammatory dermatoses |
US6592852B1 (en) | 2002-04-25 | 2003-07-15 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Zinc citrate beads in oral compositions |
US20030224023A1 (en) | 2002-05-29 | 2003-12-04 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Cosmetic compositions with hydroxy amine salts of malonic acid |
US20030224027A1 (en) | 2002-05-29 | 2003-12-04 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Cosmetic compositions with ammonium malonates |
CA2487475A1 (fr) | 2002-05-31 | 2003-12-11 | Rhodia Chimie | Procede de formation d'une liaison carbone-carbone ou carbone-heteroatome |
US6964782B1 (en) | 2002-07-23 | 2005-11-15 | Tec Labs, Inc. | Stable hydrogen peroxide compositions, products and methods of use |
US20040185016A1 (en) | 2002-07-30 | 2004-09-23 | Popp Karl F | Compositions for treatment of hyperpigmentation and methods for making and using such compositions |
US6911196B2 (en) | 2002-07-31 | 2005-06-28 | Samir I. Hamtini | Topical medicament for treating nappy rash |
US6932976B2 (en) | 2002-08-08 | 2005-08-23 | Kimberly-Clark Worldwide, Inc. | Enzyme blocking skin protectant cream |
US7208170B2 (en) | 2002-09-20 | 2007-04-24 | Petersson Lennart G | Powder teat dip germicide, fungicide and skin conditioner |
JP3874412B2 (ja) | 2002-09-30 | 2007-01-31 | 株式会社資生堂 | 皮膚外用剤 |
US6743416B2 (en) | 2002-09-30 | 2004-06-01 | Bonnie Riedl | Sunscreen for animals |
JP4168170B2 (ja) * | 2002-10-10 | 2008-10-22 | 独立行政法人産業技術総合研究所 | アルブチンエステル化合物及びその製造方法 |
SG172478A1 (en) | 2002-10-25 | 2011-07-28 | Revance Therapeutics Inc | Modulation of zinc levels to improve tissue properties |
US6855341B2 (en) | 2002-11-04 | 2005-02-15 | Jeffrey B. Smith | Anti-viral compositions and methods of making and using the anti-viral compositions |
US20040091551A1 (en) | 2002-11-13 | 2004-05-13 | Al-Karim Damji | Topical composition and application system |
US20040101541A1 (en) | 2002-11-27 | 2004-05-27 | Heffernan Michael Scully | Electrolytic cream |
US6979468B1 (en) | 2002-12-06 | 2005-12-27 | Sirius Laboratories | Oral composition and method for the treatment of inflammatory cutaneous disorders |
US20040185015A1 (en) | 2003-03-17 | 2004-09-23 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Sunscreen cosmetic compositions storage stabilized with malonate salts |
US20040185074A1 (en) | 2003-03-17 | 2004-09-23 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Odor control in amine salt containing cosmetic compositions |
US20040202689A1 (en) | 2003-03-17 | 2004-10-14 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Terpenoid fragrance components stabilized with malonic acid salts |
US20070059381A1 (en) | 2003-06-20 | 2007-03-15 | Barker Ronnie C | Treatment of amd with combination of ingredients |
WO2005002597A1 (en) | 2003-07-02 | 2005-01-13 | Polycord, Inc. | Method for delivering polymerized therapeutic agent compositions and compositions thereof |
DE20311089U1 (de) * | 2003-07-18 | 2004-08-26 | Proagil Gmbh | Kosmetische Zusammensetzung enthaltend mindestens einen phytosteroidhaltigen Extrakt |
EP1651237B1 (en) | 2003-08-04 | 2012-09-19 | Johnson & Johnson Consumer Companies, Inc. | Methods for treatment of dermatological conditions |
US20050100571A1 (en) | 2003-11-10 | 2005-05-12 | Larry Keyes | Method and device to treat skin affected by a corn |
US7258875B2 (en) | 2003-12-04 | 2007-08-21 | Chiou Consulting, Inc. | Compositions and methods for topical treatment of skin infection |
US20050175719A1 (en) | 2004-02-05 | 2005-08-11 | Ying Sun | Procyanidins for treatment and prevention of enzymatic irritation to the skin |
US7404949B2 (en) | 2004-03-15 | 2008-07-29 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Methods and compositions useful to prevent in-grown hair arising from shaving |
WO2006022899A2 (en) | 2004-08-12 | 2006-03-02 | King Industries, Inc. | Organometallic compositions and coating compositions |
US20070154419A1 (en) * | 2005-12-30 | 2007-07-05 | Judy Hattendorf | Method of treating skin requiring chemical peel procedure |
US20070154417A1 (en) * | 2005-12-30 | 2007-07-05 | Judy Hattendorf | Method of treating skin requiring non-ablative procedure |
US7687650B2 (en) * | 2006-02-03 | 2010-03-30 | Jr Chem, Llc | Chemical compositions and methods of making them |
US7897800B2 (en) * | 2006-02-03 | 2011-03-01 | Jr Chem, Llc | Chemical compositions and methods of making them |
AU2006337161B2 (en) | 2006-02-03 | 2012-06-07 | Obagi Cosmeceuticals Llc | Anti-aging treatment using copper and zinc compositions |
US20070190190A1 (en) | 2006-02-14 | 2007-08-16 | Ramirez Jose E | Conditioning compositions and methods of use thereof |
US7867522B2 (en) | 2006-09-28 | 2011-01-11 | Jr Chem, Llc | Method of wound/burn healing using copper-zinc compositions |
-
2008
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- 2008-12-19 EP EP08022201A patent/EP2087880A3/en not_active Withdrawn
- 2008-12-19 MX MX2008016502A patent/MX2008016502A/es unknown
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2012
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AU2009200009B2 (en) | 2014-10-30 |
US20090176876A1 (en) | 2009-07-09 |
AU2009200009A1 (en) | 2009-07-23 |
JP2009161529A (ja) | 2009-07-23 |
US20120312717A1 (en) | 2012-12-13 |
AU2009200009C1 (en) | 2015-12-17 |
EP2087880A2 (en) | 2009-08-12 |
EP2087880A3 (en) | 2011-05-04 |
US8505730B2 (en) | 2013-08-13 |
US8273791B2 (en) | 2012-09-25 |
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