JP5979684B2 - 莢膜多糖の収量向上のための細菌培養方法 - Google Patents

莢膜多糖の収量向上のための細菌培養方法 Download PDF

Info

Publication number
JP5979684B2
JP5979684B2 JP2014546735A JP2014546735A JP5979684B2 JP 5979684 B2 JP5979684 B2 JP 5979684B2 JP 2014546735 A JP2014546735 A JP 2014546735A JP 2014546735 A JP2014546735 A JP 2014546735A JP 5979684 B2 JP5979684 B2 JP 5979684B2
Authority
JP
Japan
Prior art keywords
range
fed
culture method
batch
bacterial culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2014546735A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015500649A (ja
Inventor
カプレ サブハッシュ ヴィナヤック,
カプレ サブハッシュ ヴィナヤック,
スワパン クマール ジャーナ,
スワパン クマール ジャーナ,
アマール クマール スリバスタバ,
アマール クマール スリバスタバ,
Original Assignee
セラム インスティチュート オブ インディア プライベイト リミテッド
セラム インスティチュート オブ インディア プライベイト リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by セラム インスティチュート オブ インディア プライベイト リミテッド, セラム インスティチュート オブ インディア プライベイト リミテッド filed Critical セラム インスティチュート オブ インディア プライベイト リミテッド
Publication of JP2015500649A publication Critical patent/JP2015500649A/ja
Application granted granted Critical
Publication of JP5979684B2 publication Critical patent/JP5979684B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2014546735A 2011-12-15 2011-12-15 莢膜多糖の収量向上のための細菌培養方法 Active JP5979684B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2011/000861 WO2013088448A1 (en) 2011-12-15 2011-12-15 A novel process of cultivating bacteria for yield improvement of capsular polyoses

Publications (2)

Publication Number Publication Date
JP2015500649A JP2015500649A (ja) 2015-01-08
JP5979684B2 true JP5979684B2 (ja) 2016-08-24

Family

ID=48611955

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014546735A Active JP5979684B2 (ja) 2011-12-15 2011-12-15 莢膜多糖の収量向上のための細菌培養方法

Country Status (11)

Country Link
US (1) US9249439B2 (enExample)
EP (1) EP2791317B1 (enExample)
JP (1) JP5979684B2 (enExample)
KR (1) KR101849642B1 (enExample)
CN (1) CN104080904B (enExample)
BR (1) BR112014014656B1 (enExample)
CA (1) CA2859124C (enExample)
IN (1) IN2014MN02530A (enExample)
MX (1) MX348547B (enExample)
WO (1) WO2013088448A1 (enExample)
ZA (1) ZA201405160B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101602286B1 (ko) 2011-07-13 2016-03-10 푸드체크 시스템스, 아이엔씨. 리스테리아를 배양하기 위한 배양 배지, 방법, 및 리스테리아를 검출하기 위한 방법
JP6391956B2 (ja) * 2014-03-20 2018-09-19 コスモAla株式会社 5−アミノレブリン酸又はその塩の製造方法
JP6391957B2 (ja) * 2014-03-20 2018-09-19 コスモAla株式会社 5−アミノレブリン酸又はその塩の製造方法
IL259404B2 (en) * 2015-11-17 2025-08-01 Pfizer Media and fermentation methods for producing polysaccharides in bacterial cell culture
CN107936128B (zh) * 2017-11-22 2020-07-03 成都欧林生物科技股份有限公司 一种简便有效的细菌疫苗纯化方法
CN107746824A (zh) * 2017-11-30 2018-03-02 成都欧林生物科技股份有限公司 肺炎链球菌的液体培养基
US12473379B2 (en) 2019-09-06 2025-11-18 Serum Institute Of India Private Limited Method for obtaining purified bacterial polysaccharides
WO2021229604A1 (en) 2020-05-14 2021-11-18 Serum Institute Of India Private Limited Methods for simultaneous fragmentation and purification of bacterial polysaccharides
CN111893084A (zh) * 2020-08-21 2020-11-06 上海荣盛生物药业有限公司 肺炎链球菌高密度发酵培养基及其方法
CN115011496A (zh) * 2021-03-04 2022-09-06 华东理工大学 高密度培养海洋病原菌大菱鲆弧菌的培养基及培养方法
CN114350571B (zh) * 2022-02-09 2024-04-19 广州知易生物科技有限公司 非动物源性培养基及用其培养嗜黏蛋白阿克曼氏菌的方法
CA3232076A1 (en) 2023-04-17 2025-04-14 Serum Institute Of India Private Limited Methods for improving the adsorption of polysaccharide-protein conjugates and multivalent vaccine formulation obtained thereof
CN117821342B (zh) * 2024-02-29 2024-06-04 北京民海生物科技有限公司 一种14型肺炎链球菌的发酵方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1356073T3 (da) * 2000-10-20 2010-04-06 Bioneer As Fermenteringsfremgangsmåde til fremstilling af heterologe genprodukter i mælkesyrebakterier
EP1664319B1 (en) * 2003-09-11 2010-03-10 De Staat der Nederlanden, vert. door de minister van VWS Process for producing a capsular polysaccharide for use in conjugate vaccines
GB0502096D0 (en) * 2005-02-01 2005-03-09 Chiron Srl Purification of streptococcal capsular polysaccharide
GB0522303D0 (en) * 2005-11-01 2005-12-07 Chiron Srl Culture method
GB0818453D0 (en) * 2008-10-08 2008-11-12 Novartis Ag Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
WO2010080486A2 (en) * 2008-12-18 2010-07-15 Wyeth Llc Method for controlling streptococcus pneumoniae serotype 19a polysaccharide molecular weight

Also Published As

Publication number Publication date
US9249439B2 (en) 2016-02-02
CN104080904A (zh) 2014-10-01
CN104080904B (zh) 2017-06-30
WO2013088448A1 (en) 2013-06-20
EP2791317B1 (en) 2017-02-01
CA2859124C (en) 2017-07-11
IN2014MN02530A (enExample) 2015-07-24
BR112014014656A8 (pt) 2017-06-13
EP2791317A4 (en) 2015-08-12
MX2014007268A (es) 2014-10-13
KR20140109967A (ko) 2014-09-16
MX348547B (es) 2017-06-19
BR112014014656A2 (pt) 2017-06-13
EP2791317A1 (en) 2014-10-22
KR101849642B1 (ko) 2018-04-17
CA2859124A1 (en) 2013-06-20
US20140342411A1 (en) 2014-11-20
ZA201405160B (en) 2015-12-23
BR112014014656B1 (pt) 2020-03-17
JP2015500649A (ja) 2015-01-08

Similar Documents

Publication Publication Date Title
JP2015500649A (ja) 莢膜多糖の収量向上のための細菌培養方法
JP7728007B2 (ja) 難培養性嫌気性微生物の高収率培養のための培地サプリメント及びそれを含む培地組成物
HK1259103A1 (zh) 用於在细菌细胞培养物中生产多糖的培养基和发酵方法
US20080274515A1 (en) Animal component free meningococcal polysaccharide fermentation and seedbank development
KR102637436B1 (ko) Crm197의 높은 수준의 생산을 위한 개선된 방법
KR20150036311A (ko) 헤모필루스 인플루엔자에 비형 항원의 생산 방법
EP2952586A1 (en) Bacterial capsular polysaccharide yield enhancement by addition of defoaming agents
CN104093416B (zh) 发酵方法
CN118497089B (zh) 一种通过细菌发酵产生细菌外膜囊泡的方法
JP7151049B2 (ja) 微生物を増殖させる方法
CN119955690B (zh) 一种生产外膜囊泡的化学限定培养基及其用途
JP5681637B2 (ja) 二酸化炭素が濃縮された空気の供給下の液体培養培地中でアクチノバシラス・プルロニューモニエ毒素ApxIまたはApcIIIを産生させる方法
CN101319235B (zh) 一种添加葡萄糖酸钠提高发酵法生产丙酮酸产量的方法
WO2004033623A2 (en) Animal component free meningococcal polysaccharide fermentation and seedbank development
CA3060723C (en) An improved method for high level production of crm197
EA045614B1 (ru) Улучшенный способ крупномасштабного производства crm197
CN106520865A (zh) 一种链霉素的生物发酵方法

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20141208

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20160105

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160405

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20160426

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160526

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20160621

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20160720

R150 Certificate of patent or registration of utility model

Ref document number: 5979684

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250