CN104080904B - 培养细菌以提高荚膜多糖产率的新方法 - Google Patents

培养细菌以提高荚膜多糖产率的新方法 Download PDF

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CN104080904B
CN104080904B CN201180076292.1A CN201180076292A CN104080904B CN 104080904 B CN104080904 B CN 104080904B CN 201180076292 A CN201180076292 A CN 201180076292A CN 104080904 B CN104080904 B CN 104080904B
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CN104080904A (zh
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K·S·维纳亚克
J·S·库马尔
A·K·斯里瓦斯塔瓦
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN201180076292.1A 2011-12-15 2011-12-15 培养细菌以提高荚膜多糖产率的新方法 Active CN104080904B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2011/000861 WO2013088448A1 (en) 2011-12-15 2011-12-15 A novel process of cultivating bacteria for yield improvement of capsular polyoses

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CN104080904A CN104080904A (zh) 2014-10-01
CN104080904B true CN104080904B (zh) 2017-06-30

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US (1) US9249439B2 (enExample)
EP (1) EP2791317B1 (enExample)
JP (1) JP5979684B2 (enExample)
KR (1) KR101849642B1 (enExample)
CN (1) CN104080904B (enExample)
BR (1) BR112014014656B1 (enExample)
CA (1) CA2859124C (enExample)
IN (1) IN2014MN02530A (enExample)
MX (1) MX348547B (enExample)
WO (1) WO2013088448A1 (enExample)
ZA (1) ZA201405160B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101602286B1 (ko) 2011-07-13 2016-03-10 푸드체크 시스템스, 아이엔씨. 리스테리아를 배양하기 위한 배양 배지, 방법, 및 리스테리아를 검출하기 위한 방법
JP6391956B2 (ja) * 2014-03-20 2018-09-19 コスモＡｌａ株式会社 ５−アミノレブリン酸又はその塩の製造方法
JP6391957B2 (ja) * 2014-03-20 2018-09-19 コスモＡｌａ株式会社 ５−アミノレブリン酸又はその塩の製造方法
IL259404B2 (en) * 2015-11-17 2025-08-01 Pfizer Media and fermentation methods for producing polysaccharides in bacterial cell culture
CN107936128B (zh) * 2017-11-22 2020-07-03 成都欧林生物科技股份有限公司 一种简便有效的细菌疫苗纯化方法
CN107746824A (zh) * 2017-11-30 2018-03-02 成都欧林生物科技股份有限公司 肺炎链球菌的液体培养基
US12473379B2 (en) 2019-09-06 2025-11-18 Serum Institute Of India Private Limited Method for obtaining purified bacterial polysaccharides
WO2021229604A1 (en) 2020-05-14 2021-11-18 Serum Institute Of India Private Limited Methods for simultaneous fragmentation and purification of bacterial polysaccharides
CN111893084A (zh) * 2020-08-21 2020-11-06 上海荣盛生物药业有限公司 肺炎链球菌高密度发酵培养基及其方法
CN115011496A (zh) * 2021-03-04 2022-09-06 华东理工大学 高密度培养海洋病原菌大菱鲆弧菌的培养基及培养方法
CN114350571B (zh) * 2022-02-09 2024-04-19 广州知易生物科技有限公司 非动物源性培养基及用其培养嗜黏蛋白阿克曼氏菌的方法
CA3232076A1 (en) 2023-04-17 2025-04-14 Serum Institute Of India Private Limited Methods for improving the adsorption of polysaccharide-protein conjugates and multivalent vaccine formulation obtained thereof
CN117821342B (zh) * 2024-02-29 2024-06-04 北京民海生物科技有限公司 一种14型肺炎链球菌的发酵方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101932698A (zh) * 2007-12-20 2010-12-29 诺华有限公司 培养链球菌的发酵工艺以及从中提取cps的纯化工艺
CN102257155A (zh) * 2008-12-18 2011-11-23 惠氏有限责任公司 控制肺炎链球菌血清型19a多糖分子量的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1356073T3 (da) * 2000-10-20 2010-04-06 Bioneer As Fermenteringsfremgangsmåde til fremstilling af heterologe genprodukter i mælkesyrebakterier
EP1664319B1 (en) * 2003-09-11 2010-03-10 De Staat der Nederlanden, vert. door de minister van VWS Process for producing a capsular polysaccharide for use in conjugate vaccines
GB0502096D0 (en) * 2005-02-01 2005-03-09 Chiron Srl Purification of streptococcal capsular polysaccharide
GB0522303D0 (en) * 2005-11-01 2005-12-07 Chiron Srl Culture method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101932698A (zh) * 2007-12-20 2010-12-29 诺华有限公司 培养链球菌的发酵工艺以及从中提取cps的纯化工艺
CN102257155A (zh) * 2008-12-18 2011-11-23 惠氏有限责任公司 控制肺炎链球菌血清型19a多糖分子量的方法

Also Published As

Publication number Publication date
US9249439B2 (en) 2016-02-02
CN104080904A (zh) 2014-10-01
WO2013088448A1 (en) 2013-06-20
EP2791317B1 (en) 2017-02-01
CA2859124C (en) 2017-07-11
IN2014MN02530A (enExample) 2015-07-24
BR112014014656A8 (pt) 2017-06-13
EP2791317A4 (en) 2015-08-12
MX2014007268A (es) 2014-10-13
KR20140109967A (ko) 2014-09-16
MX348547B (es) 2017-06-19
BR112014014656A2 (pt) 2017-06-13
EP2791317A1 (en) 2014-10-22
KR101849642B1 (ko) 2018-04-17
JP5979684B2 (ja) 2016-08-24
CA2859124A1 (en) 2013-06-20
US20140342411A1 (en) 2014-11-20
ZA201405160B (en) 2015-12-23
BR112014014656B1 (pt) 2020-03-17
JP2015500649A (ja) 2015-01-08

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