MX348547B - Nuevo proceso para cultivar bacterias para el mejoramiento del rendimiento de las poliosas capsulares. - Google Patents
Nuevo proceso para cultivar bacterias para el mejoramiento del rendimiento de las poliosas capsulares.Info
- Publication number
- MX348547B MX348547B MX2014007268A MX2014007268A MX348547B MX 348547 B MX348547 B MX 348547B MX 2014007268 A MX2014007268 A MX 2014007268A MX 2014007268 A MX2014007268 A MX 2014007268A MX 348547 B MX348547 B MX 348547B
- Authority
- MX
- Mexico
- Prior art keywords
- novel process
- yield improvement
- cultivating bacteria
- polyoses
- capsular
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La presente invención se refiere a un método para cultivar bacterias capsuladas para la producción volumétrica mayor de poliosas capsulares (CP) en comparación con la fermentación en modo por lotes, caracterizado porque comprende: (a) proporcionar un inóculo de una cepa de las bacterias que expresan la CP; (b) cultivar la cepa mediante fermentación a pH 7.2, en donde la velocidad de adición del medio de alimentación es equivalente a la velocidad de adición de la mezcla de álcali para mantener un pH preestablecido, en donde la mezcla de álcali contiene carbonato de sodio; (c) fermentar el medio de cultivo a 35.38°C bajo agitación a 50-150 RPM con una velocidad de flujo de aire de 0.1-05 vvm, en donde las bacterias son desarrolladas en el cultivo de lote alimentado.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IN2011/000861 WO2013088448A1 (en) | 2011-12-15 | 2011-12-15 | A novel process of cultivating bacteria for yield improvement of capsular polyoses |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014007268A MX2014007268A (es) | 2014-10-13 |
MX348547B true MX348547B (es) | 2017-06-19 |
Family
ID=48611955
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014007268A MX348547B (es) | 2011-12-15 | 2011-12-15 | Nuevo proceso para cultivar bacterias para el mejoramiento del rendimiento de las poliosas capsulares. |
Country Status (10)
Country | Link |
---|---|
US (1) | US9249439B2 (es) |
EP (1) | EP2791317B1 (es) |
JP (1) | JP5979684B2 (es) |
KR (1) | KR101849642B1 (es) |
CN (1) | CN104080904B (es) |
BR (1) | BR112014014656B1 (es) |
CA (1) | CA2859124C (es) |
MX (1) | MX348547B (es) |
WO (1) | WO2013088448A1 (es) |
ZA (1) | ZA201405160B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2841820C (en) | 2011-07-13 | 2017-01-03 | Foodchek Systems Inc. | Culture medium, method for culturing listeria, and method for detecting listeria |
JP6391957B2 (ja) * | 2014-03-20 | 2018-09-19 | コスモAla株式会社 | 5−アミノレブリン酸又はその塩の製造方法 |
JP6391956B2 (ja) * | 2014-03-20 | 2018-09-19 | コスモAla株式会社 | 5−アミノレブリン酸又はその塩の製造方法 |
AU2016357567B2 (en) * | 2015-11-17 | 2020-05-07 | Pfizer Inc. | Media and fermentation methods for producing polysaccharides in bacterial cell culture |
CN107936128B (zh) * | 2017-11-22 | 2020-07-03 | 成都欧林生物科技股份有限公司 | 一种简便有效的细菌疫苗纯化方法 |
CN107746824A (zh) * | 2017-11-30 | 2018-03-02 | 成都欧林生物科技股份有限公司 | 肺炎链球菌的液体培养基 |
US20210070890A1 (en) | 2019-09-06 | 2021-03-11 | Serum Institute Of India Private Limited | Method for obtaining purified bacterial polysaccharides |
WO2021229604A1 (en) | 2020-05-14 | 2021-11-18 | Serum Institute Of India Private Limited | Methods for simultaneous fragmentation and purification of bacterial polysaccharides |
CN111893084A (zh) * | 2020-08-21 | 2020-11-06 | 上海荣盛生物药业有限公司 | 肺炎链球菌高密度发酵培养基及其方法 |
CN115011496A (zh) * | 2021-03-04 | 2022-09-06 | 华东理工大学 | 高密度培养海洋病原菌大菱鲆弧菌的培养基及培养方法 |
CN114350571B (zh) * | 2022-02-09 | 2024-04-19 | 广州知易生物科技有限公司 | 非动物源性培养基及用其培养嗜黏蛋白阿克曼氏菌的方法 |
EP4450082A1 (en) | 2023-04-17 | 2024-10-23 | Serum Institute Of India Private Limited | Methods for improving the adsorption of polysaccharide-protein conjugates and multivalent vaccine formulation obtained thereof |
CN117821342B (zh) * | 2024-02-29 | 2024-06-04 | 北京民海生物科技有限公司 | 一种14型肺炎链球菌的发酵方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2426084C (en) * | 2000-10-20 | 2013-12-10 | Bioteknologisk Institut | Improved fermentation method for production of heterologous gene products in lactic acid bacteria |
ATE460498T1 (de) * | 2003-09-11 | 2010-03-15 | Staat Der Nederlanden Vert Doo | Verfahren zur herstellung eines kapselpolysaccharids zur verwendung in konjugat- impfstoffen |
GB0502096D0 (en) * | 2005-02-01 | 2005-03-09 | Chiron Srl | Purification of streptococcal capsular polysaccharide |
GB0522303D0 (en) * | 2005-11-01 | 2005-12-07 | Chiron Srl | Culture method |
GB0818453D0 (en) * | 2008-10-08 | 2008-11-12 | Novartis Ag | Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom |
WO2010080486A2 (en) * | 2008-12-18 | 2010-07-15 | Wyeth Llc | Method for controlling streptococcus pneumoniae serotype 19a polysaccharide molecular weight |
-
2011
- 2011-12-15 MX MX2014007268A patent/MX348547B/es active IP Right Grant
- 2011-12-15 WO PCT/IN2011/000861 patent/WO2013088448A1/en active Application Filing
- 2011-12-15 JP JP2014546735A patent/JP5979684B2/ja active Active
- 2011-12-15 BR BR112014014656-0A patent/BR112014014656B1/pt active IP Right Grant
- 2011-12-15 EP EP11877405.8A patent/EP2791317B1/en active Active
- 2011-12-15 US US14/365,959 patent/US9249439B2/en active Active
- 2011-12-15 CN CN201180076292.1A patent/CN104080904B/zh active Active
- 2011-12-15 KR KR1020147019651A patent/KR101849642B1/ko active IP Right Grant
- 2011-12-15 CA CA2859124A patent/CA2859124C/en active Active
-
2014
- 2014-07-15 ZA ZA2014/05160A patent/ZA201405160B/en unknown
Also Published As
Publication number | Publication date |
---|---|
CA2859124C (en) | 2017-07-11 |
EP2791317B1 (en) | 2017-02-01 |
JP5979684B2 (ja) | 2016-08-24 |
EP2791317A1 (en) | 2014-10-22 |
KR101849642B1 (ko) | 2018-04-17 |
EP2791317A4 (en) | 2015-08-12 |
CA2859124A1 (en) | 2013-06-20 |
BR112014014656A2 (pt) | 2017-06-13 |
BR112014014656B1 (pt) | 2020-03-17 |
CN104080904B (zh) | 2017-06-30 |
CN104080904A (zh) | 2014-10-01 |
KR20140109967A (ko) | 2014-09-16 |
US9249439B2 (en) | 2016-02-02 |
JP2015500649A (ja) | 2015-01-08 |
US20140342411A1 (en) | 2014-11-20 |
WO2013088448A1 (en) | 2013-06-20 |
ZA201405160B (en) | 2015-12-23 |
MX2014007268A (es) | 2014-10-13 |
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