WO2013005209A3 - Enhanced lipid production by algae - Google Patents

Enhanced lipid production by algae Download PDF

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Publication number
WO2013005209A3
WO2013005209A3 PCT/IL2012/050230 IL2012050230W WO2013005209A3 WO 2013005209 A3 WO2013005209 A3 WO 2013005209A3 IL 2012050230 W IL2012050230 W IL 2012050230W WO 2013005209 A3 WO2013005209 A3 WO 2013005209A3
Authority
WO
WIPO (PCT)
Prior art keywords
algae
lipid production
enhanced lipid
present
triglyceride
Prior art date
Application number
PCT/IL2012/050230
Other languages
French (fr)
Other versions
WO2013005209A2 (en
Inventor
Uri Pick
Tatyana RACHUTIN ZALOGIN
Original Assignee
Yeda Research And Development Co. Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research And Development Co. Ltd. filed Critical Yeda Research And Development Co. Ltd.
Publication of WO2013005209A2 publication Critical patent/WO2013005209A2/en
Publication of WO2013005209A3 publication Critical patent/WO2013005209A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6463—Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention provides methods for efficient production of triglycerides by microalgae, useful as a source for biodiesel. Particularly, the present invention discloses the use of cytochrome oxidase inhibitor to induce triglyceride accumulation while maintaining high growth rate, resulting in high triglyceride yield.
PCT/IL2012/050230 2011-07-04 2012-07-03 Enhanced lipid production by algae WO2013005209A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161504253P 2011-07-04 2011-07-04
US61/504,253 2011-07-04

Publications (2)

Publication Number Publication Date
WO2013005209A2 WO2013005209A2 (en) 2013-01-10
WO2013005209A3 true WO2013005209A3 (en) 2013-04-11

Family

ID=46642593

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2012/050230 WO2013005209A2 (en) 2011-07-04 2012-07-03 Enhanced lipid production by algae

Country Status (1)

Country Link
WO (1) WO2013005209A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3447124B1 (en) * 2015-03-31 2021-12-22 Corbion Biotech, Inc. Microalgae adapted for heterotrophic culture conditions
WO2017033188A1 (en) 2015-08-24 2017-03-02 Yeda Research And Development Co. Ltd. Algal oil and biofuel and methods of producing same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090148928A1 (en) 2007-11-29 2009-06-11 Hackworth Cheryl A Heterotrophic Shift
CN101280328B (en) 2008-05-27 2011-06-29 清华大学 Method for producing biodiesel by autotrophic culture and heterotrophic culture of chlorella
WO2010080377A1 (en) 2008-12-19 2010-07-15 Alpha-J Research Limited Partnership Optimization of algal product production through uncoupling cell proliferation and algal product production
US20120095245A1 (en) 2009-05-11 2012-04-19 Phycal, Inc. Biofuel production from algae

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HU QIANG ET AL: "Microalgal triacylglycerols as feedstocks for biofuel production: perspectives and advances", THE PLANT JOURNAL, BLACKWELL SCIENTIFIC PUBLICATIONS, OXFORD, GB, vol. 54, no. 4, 1 May 2008 (2008-05-01), pages 621 - 639, XP009130325, ISSN: 0960-7412, DOI: 10.1111/J.1365-313X.2008.03492.X *
SHARMA K.K. ET AL.: "High lipid induction in microalgae for biodiesel production", ENERGIES, vol. 5, 18 May 2012 (2012-05-18), pages 1532 - 1553, XP002689116 *
TAKAGI M ET AL: "Effect of salt concentration on intracellular accumulation of lipids and triacylglyceride in marine microalgae Dunaliella cells", JOURNAL OF BIOSCIENCE AND BIOENGINEERING, ELSEVIER, AMSTERDAM, NL, vol. 101, no. 3, 1 March 2006 (2006-03-01), pages 223 - 226, XP028042319, ISSN: 1389-1723, [retrieved on 20060301], DOI: 10.1263/JBB.101.223 *
WEI-LUEN YU ET AL: "Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae", MICROBIAL CELL FACTORIES, BIOMED CENTRAL, LONDON, NL, vol. 10, no. 1, 2 November 2011 (2011-11-02), pages 91, XP021112003, ISSN: 1475-2859, DOI: 10.1186/1475-2859-10-91 *

Also Published As

Publication number Publication date
WO2013005209A2 (en) 2013-01-10

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