JP5658139B2 - Ｂａｃｅ阻害剤 - Google Patents

Ｂａｃｅ阻害剤 Download PDF

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Publication number
JP5658139B2
JP5658139B2 JP2011507529A JP2011507529A JP5658139B2 JP 5658139 B2 JP5658139 B2 JP 5658139B2 JP 2011507529 A JP2011507529 A JP 2011507529A JP 2011507529 A JP2011507529 A JP 2011507529A JP 5658139 B2 JP5658139 B2 JP 5658139B2
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compound
methyl
mmol
dihydro
formula
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Japanese (ja)
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JP2011519854A5 (enExample
JP2011519854A (ja
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ジェイムズ・エドマンド・オーディア
ダスティン・ジェイムズ・マーゴット
スコット・マーティン・シーハン
ブライアン・モーガン・ワトソン
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イーライ リリー アンド カンパニー
イーライ リリー アンド カンパニー
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
    • C07D279/06—1,3-Thiazines; Hydrogenated 1,3-thiazines not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2011507529A 2008-05-02 2009-04-15 Ｂａｃｅ阻害剤 Expired - Fee Related JP5658139B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4988108P 2008-05-02 2008-05-02
US61/049,881 2008-05-02
PCT/US2009/040589 WO2009134617A1 (en) 2008-05-02 2009-04-15 Aminodihydrothiazine derivatives as bace inhibitors for the treatment of alzheimer's disease

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014208277A Division JP2015051980A (ja) 2008-05-02 2014-10-09 Ｂａｃｅ阻害剤

Publications (3)

Publication Number Publication Date
JP2011519854A JP2011519854A (ja) 2011-07-14
JP2011519854A5 JP2011519854A5 (enExample) 2012-06-07
JP5658139B2 true JP5658139B2 (ja) 2015-01-21

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ID=40839645

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2011507529A Expired - Fee Related JP5658139B2 (ja) 2008-05-02 2009-04-15 Ｂａｃｅ阻害剤
JP2014208277A Pending JP2015051980A (ja) 2008-05-02 2014-10-09 Ｂａｃｅ阻害剤
JP2016211189A Withdrawn JP2017048212A (ja) 2008-05-02 2016-10-28 Ｂａｃｅ阻害剤

Family Applications After (2)

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JP2014208277A Pending JP2015051980A (ja) 2008-05-02 2014-10-09 Ｂａｃｅ阻害剤
JP2016211189A Withdrawn JP2017048212A (ja) 2008-05-02 2016-10-28 Ｂａｃｅ阻害剤

Country Status (32)

Country Link
US (1) US7648983B2 (enExample)
EP (1) EP2297120B1 (enExample)
JP (3) JP5658139B2 (enExample)
KR (1) KR101253835B1 (enExample)
CN (1) CN102015667B (enExample)
AR (1) AR071187A1 (enExample)
AU (1) AU2009241515B2 (enExample)
CA (1) CA2723207C (enExample)
CL (1) CL2009000860A1 (enExample)
CO (1) CO6311079A2 (enExample)
CR (1) CR11776A (enExample)
DK (1) DK2297120T3 (enExample)
DO (1) DOP2010000328A (enExample)
EA (1) EA016955B1 (enExample)
EC (1) ECSP10010582A (enExample)
ES (1) ES2549087T3 (enExample)
HR (1) HRP20150941T1 (enExample)
HU (1) HUE025520T2 (enExample)
IL (1) IL208350A (enExample)
MA (1) MA32351B1 (enExample)
MX (1) MX2010011972A (enExample)
NZ (1) NZ588300A (enExample)
PE (1) PE20091816A1 (enExample)
PL (1) PL2297120T3 (enExample)
PT (1) PT2297120E (enExample)
RS (1) RS54260B1 (enExample)
SI (1) SI2297120T1 (enExample)
SV (1) SV2010003718A (enExample)
TW (1) TWI431004B (enExample)
UA (1) UA102251C2 (enExample)
WO (1) WO2009134617A1 (enExample)
ZA (1) ZA201006868B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015051980A (ja) * 2008-05-02 2015-03-19 イーライ リリー アンド カンパニー Ｂａｃｅ阻害剤

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