ZA201006868B - Aminodihydrothiazine derivatives as bace inhibitors for the treatment of alzheimer's disease - Google Patents

Aminodihydrothiazine derivatives as bace inhibitors for the treatment of alzheimer's disease

Info

Publication number
ZA201006868B
ZA201006868B ZA2010/06868A ZA201006868A ZA201006868B ZA 201006868 B ZA201006868 B ZA 201006868B ZA 2010/06868 A ZA2010/06868 A ZA 2010/06868A ZA 201006868 A ZA201006868 A ZA 201006868A ZA 201006868 B ZA201006868 B ZA 201006868B
Authority
ZA
South Africa
Prior art keywords
alzheimer
disease
treatment
bace inhibitors
aminodihydrothiazine derivatives
Prior art date
Application number
ZA2010/06868A
Other languages
English (en)
Inventor
James Edmund Audia
Dustin James Mergott
Scott Martin Sheehan
Brian Morgan Watson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40839645&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA201006868(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA201006868B publication Critical patent/ZA201006868B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
    • C07D279/06—1,3-Thiazines; Hydrogenated 1,3-thiazines not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA2010/06868A 2008-05-02 2010-09-27 Aminodihydrothiazine derivatives as bace inhibitors for the treatment of alzheimer's disease ZA201006868B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4988108P 2008-05-02 2008-05-02
PCT/US2009/040589 WO2009134617A1 (en) 2008-05-02 2009-04-15 Aminodihydrothiazine derivatives as bace inhibitors for the treatment of alzheimer's disease

Publications (1)

Publication Number Publication Date
ZA201006868B true ZA201006868B (en) 2012-03-28

Family

ID=40839645

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2010/06868A ZA201006868B (en) 2008-05-02 2010-09-27 Aminodihydrothiazine derivatives as bace inhibitors for the treatment of alzheimer's disease

Country Status (32)

Country Link
US (1) US7648983B2 (enExample)
EP (1) EP2297120B1 (enExample)
JP (3) JP5658139B2 (enExample)
KR (1) KR101253835B1 (enExample)
CN (1) CN102015667B (enExample)
AR (1) AR071187A1 (enExample)
AU (1) AU2009241515B2 (enExample)
CA (1) CA2723207C (enExample)
CL (1) CL2009000860A1 (enExample)
CO (1) CO6311079A2 (enExample)
CR (1) CR11776A (enExample)
DK (1) DK2297120T3 (enExample)
DO (1) DOP2010000328A (enExample)
EA (1) EA016955B1 (enExample)
EC (1) ECSP10010582A (enExample)
ES (1) ES2549087T3 (enExample)
HR (1) HRP20150941T1 (enExample)
HU (1) HUE025520T2 (enExample)
IL (1) IL208350A (enExample)
MA (1) MA32351B1 (enExample)
MX (1) MX2010011972A (enExample)
NZ (1) NZ588300A (enExample)
PE (1) PE20091816A1 (enExample)
PL (1) PL2297120T3 (enExample)
PT (1) PT2297120E (enExample)
RS (1) RS54260B1 (enExample)
SI (1) SI2297120T1 (enExample)
SV (1) SV2010003718A (enExample)
TW (1) TWI431004B (enExample)
UA (1) UA102251C2 (enExample)
WO (1) WO2009134617A1 (enExample)
ZA (1) ZA201006868B (enExample)

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Also Published As

Publication number Publication date
JP5658139B2 (ja) 2015-01-21
PL2297120T3 (pl) 2016-01-29
JP2011519854A (ja) 2011-07-14
JP2017048212A (ja) 2017-03-09
EP2297120A1 (en) 2011-03-23
CR11776A (es) 2011-01-28
KR101253835B1 (ko) 2013-04-15
ECSP10010582A (es) 2010-11-30
DOP2010000328A (es) 2010-11-15
SI2297120T1 (sl) 2015-11-30
JP2015051980A (ja) 2015-03-19
CN102015667A (zh) 2011-04-13
DK2297120T3 (en) 2015-10-12
HRP20150941T1 (hr) 2015-10-09
IL208350A (en) 2014-05-28
UA102251C2 (ru) 2013-06-25
US20090275566A1 (en) 2009-11-05
AU2009241515B2 (en) 2012-04-19
CL2009000860A1 (es) 2010-05-07
AR071187A1 (es) 2010-06-02
EA201071264A1 (ru) 2011-04-29
ES2549087T3 (es) 2015-10-22
HUE025520T2 (en) 2016-02-29
MX2010011972A (es) 2010-11-25
PT2297120E (pt) 2015-10-26
EP2297120B1 (en) 2015-08-19
CN102015667B (zh) 2013-06-12
CA2723207A1 (en) 2009-11-05
CA2723207C (en) 2016-07-12
NZ588300A (en) 2012-07-27
IL208350A0 (en) 2010-12-30
US7648983B2 (en) 2010-01-19
AU2009241515A1 (en) 2009-11-05
TW200946522A (en) 2009-11-16
RS54260B1 (sr) 2016-02-29
SV2010003718A (es) 2011-02-14
CO6311079A2 (es) 2011-08-22
KR20100125475A (ko) 2010-11-30
TWI431004B (zh) 2014-03-21
WO2009134617A1 (en) 2009-11-05
MA32351B1 (fr) 2011-06-01
PE20091816A1 (es) 2009-11-25
EA016955B1 (ru) 2012-08-30

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